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31. 发明申请

US20110313447A1 SYSTEM AND METHOD FOR MECHANICALLY POSITIONING INTRAVASCULAR IMPLANTS 有权
标题翻译：用于机械定位静脉内植入物的系统和方法
公开(公告)号：US20110313447A1
公开(公告)日：2011-12-22
申请号：US13221852
申请日：2011-08-30
申请人： Brian Michael Strauss , Earl Howard Slee , Ramon Torres Carrillo , Khoa Dang Vu , William Robert Patterson , Jessica Liang , Richard Stephen Bein , Todd Jeffrey Hewitt , Stacy Leon Faught , Vince Divino , Darrell Christopher Drysen , Mark Philip Ashby , Justin Arthur Klotz , Maria De Jesus Sanson , Scott William Brennan , Lawrason Charles Wilbur , Lester Eugene Oestreich
发明人： Brian Michael Strauss , Earl Howard Slee , Ramon Torres Carrillo , Khoa Dang Vu , William Robert Patterson , Jessica Liang , Richard Stephen Bein , Todd Jeffrey Hewitt , Stacy Leon Faught , Vince Divino , Darrell Christopher Drysen , Mark Philip Ashby , Justin Arthur Klotz , Maria De Jesus Sanson , Scott William Brennan , Lawrason Charles Wilbur , Lester Eugene Oestreich
IPC分类号： A61F2/01
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B17/12145 , A61B17/12154 , A61B17/12172 , A61B90/39 , A61B2017/1205 , A61B2017/12054 , A61B2017/2913 , A61B2017/2924 , A61F2/01 , A61F2/82 , A61F2230/0006
摘要： An intravascular implant delivery system carries an implant by retaining an engagement member engaging the implant in a position proximal of an aperture at a distal end of the delivery system. The engagement member is retained proximal to the aperture by a cord that obstructs the movement of the engagement member through the aperture. The engagement member is free to rotate and move within an area defined by the delivery system, allowing the implant to react to forces imparted to the implant by the movement of the delivery system and implant through a delivery catheter. Once the implant is in a desired implant position, the cord is moved away from an aperture and the engagement member is allowed to move away from the delivery system.
摘要翻译：血管内植入物递送系统通过将接合植入物的接合构件保持在输送系统的远端处的孔附近的位置来承载植入物。接合构件通过阻碍接合构件通过孔的运动的绳索保持在孔的近侧。接合构件在由输送系统限定的区域内自由旋转和移动，允许植入物通过输送系统的移动和植入物通过输送导管对施加到植入物的力作出反应。一旦植入物处于期望的植入位置，则绳索被移动远离孔，并且接合构件被允许远离输送系统移动。

32. 发明申请

US20110245863A1 Multi-Layer Coaxial Vaso-Occlusive Device 有权
标题翻译：多层同轴血管闭塞装置
公开(公告)号：US20110245863A1
公开(公告)日：2011-10-06
申请号：US13164446
申请日：2011-06-20
申请人： George Martinez
发明人： George Martinez
IPC分类号： A61F2/01
CPC分类号： A61L31/145 , A61B17/12022 , A61B17/12145 , A61B17/1215 , A61B17/12154 , A61B17/12177 , A61B17/1219 , A61B2017/00004 , A61B2017/0084 , A61B2017/00867 , A61B2017/12054 , A61L31/14 , A61L2430/36
摘要： A vaso-occlusive device includes inner, intermediate, and outer elements arranged coaxially. The inner element is a filamentous element, preferably a microcoil. The intermediate element is made of a non-metallic material, preferably an expansile polymer. The outer element is substantially non-expansile and defines at least one gap or opening through which the intermediate element is exposed. In a preferred embodiment, when the intermediate element is expanded, it protrudes through the at least one gap or opening in the outer element and assumes a configuration with an undulating, convexly-curved outer surface defining a chain of arcuate segments, each having a diameter significantly greater than the diameter of the outer element. The expanded configuration of the intermediate element minimizes friction when the device is deployed through a microcatheter, thereby reducing the likelihood of buckling while maintaining excellent flexibility. The result is a device with enhanced pushability and trackability when deployed through a microcatheter.
摘要翻译：血管闭塞装置包括同轴布置的内部，中间和外部元件。内部元件是丝状元件，优选为微线圈。中间元件由非金属材料制成，优选为可膨胀聚合物。外部元件基本上是非膨胀的并且限定了中间元件暴露于其中的至少一个间隙或开口。在优选实施例中，当中间元件膨胀时，其突出穿过外部元件中的至少一个间隙或开口，并呈现出具有起伏的凸形弯曲的外表面的构造，该外表面限定了弓形链节段，每个弧形段具有直径明显大于外部元件的直径。中间元件的膨胀结构在器件通过微导管部署时使摩擦最小化，从而降低屈曲的可能性，同时保持优异的柔性。结果是当通过微导管部署时具有增强的推动性和可追踪性的装置。

33. 发明申请

US20110213406A1 ANCHOR ASSEMBLIES IN STRETCH-RESISTANT VASO-OCCLUSIVE COILS 审中-公开
标题翻译：锚固组件在抗拉索性能的线圈中
公开(公告)号：US20110213406A1
公开(公告)日：2011-09-01
申请号：US13103394
申请日：2011-05-09
申请人： Nestor Aganon , Ann Huang , Maria Pizarro , John L. Minck, JR.
发明人： Nestor Aganon , Ann Huang , Maria Pizarro , John L. Minck, JR.
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/12154 , A61B2017/1205 , A61B2017/12063 , A61B2017/12095
摘要： Vaso-occlusive devices are provided for occluding an aneurysm within the human vasculature. The vaso-occlusive device also includes a stretch-resisting member that extends through at least a portion of a lumen of the primary coil and is directly or indirectly attached to the primary coil at two locations axially separated from each other to prevent or minimize axial stretching of the primary coil. At one location, the stretch-resisting member is coupled to the primary coil via a flexible anchor assembly disposed within the lumen. In one embodiment, the anchor assembly may comprise an anchor coil and a link directly or indirectly coupled between the anchor coil and the stretch-resisting member. Alternatively, the anchor assembly may comprise a chain of twisted links.
摘要翻译：提供血管闭塞装置用于阻塞人脉管系统内的动脉瘤。血管闭塞装置还包括延伸穿过初级线圈的内腔的至少一部分并且在轴向彼此分离的两个位置处直接或间接附接到初级线圈的抗拉构件，以防止或最小化轴向拉伸的初级线圈。在一个位置处，抗拉构件通过设置在内腔内的柔性锚固组件耦合到初级线圈。在一个实施例中，锚固组件可以包括锚固线圈和直接或间接地联接在锚定线圈和抗拉构件之间的连杆。或者，锚固组件可以包括扭绞链节链。

34. 发明申请

US20110184454A1 EMBOLIC IMPLANTS 审中-公开
标题翻译：嵌入式植入物
公开(公告)号：US20110184454A1
公开(公告)日：2011-07-28
申请号：US12695035
申请日：2010-01-27
申请人： David BARRY , Ben Tompkins , Delilah Hui , Arthur John Lockhart
发明人： David BARRY , Ben Tompkins , Delilah Hui , Arthur John Lockhart
IPC分类号： A61F2/01 , B23P11/00
CPC分类号： A61B17/12022 , A61B17/12027 , A61B17/12113 , A61B17/12145 , A61B17/12154 , A61B2017/00867 , Y10T29/49826
摘要： Embolic coils are disclosed. The coils include an inner coil, an outer coil, and a stretch resistant member. Some embodiments include a large diameter outer coil formed from a small diameter wire. The inner coils may be either closed pitch or open pitch. Alternative coils include an inner coil that is shape set to a diameter that is larger than the diameter of the outer coil. Another alternative coil has multiple stretch resistant members.
摘要翻译：公开了栓塞线圈。线圈包括内线圈，外线圈和抗拉构件。一些实施例包括由小直径导线形成的大直径外部线圈。内部线圈可以是闭合间距或开放节距。替代线圈包括形状设定为大于外部线圈直径的直径的内部线圈。另一替代线圈具有多个抗拉构件。

35. 发明授权

US07938845B2 Anchor assemblies in stretch-resistant vaso-occlusive coils 失效
标题翻译：拉伸抗血管闭塞线圈的锚固组件
公开(公告)号：US07938845B2
公开(公告)日：2011-05-10
申请号：US11618362
申请日：2006-12-29
申请人： Nestor Aganon , Ann Huang , Maria Pizarro , John L. Minck, Jr.
发明人： Nestor Aganon , Ann Huang , Maria Pizarro , John L. Minck, Jr.
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/12154 , A61B2017/1205 , A61B2017/12063 , A61B2017/12095
摘要： Vaso-occlusive devices are provided for occluding an aneurysm within the human vasculature. The vaso-occlusive device also includes a stretch-resisting member that extends through at least a portion of a lumen of the primary coil and is directly or indirectly attached to the primary coil at two locations axially separated from each other to prevent or minimize axial stretching of the primary coil. At one location, the stretch-resisting member is coupled to the primary coil via a flexible anchor assembly disposed within the lumen. In one embodiment, the anchor assembly may comprise an anchor coil and a link directly or indirectly coupled between the anchor coil and the stretch-resisting member. Alternatively, the anchor assembly may comprise a chain of twisted links.
摘要翻译：提供血管闭塞装置用于阻塞人脉管系统内的动脉瘤。血管闭塞装置还包括延伸穿过初级线圈的内腔的至少一部分并且在轴向彼此分离的两个位置处直接或间接附接到初级线圈的抗拉构件，以防止或最小化轴向拉伸的初级线圈。在一个位置处，抗拉构件通过设置在内腔内的柔性锚固组件耦合到初级线圈。在一个实施例中，锚固组件可以包括锚固线圈和直接或间接地联接在锚定线圈和抗拉构件之间的连杆。或者，锚固组件可以包括扭绞链节链。

36. 发明申请

US20110106098A1 OCCLUSIVE DEVICE DELIVERY SYSTEM 审中-公开
标题翻译： OCCLUSIVE设备交付系统
公开(公告)号：US20110106098A1
公开(公告)日：2011-05-05
申请号：US12913085
申请日：2010-10-27
申请人： Michael D Williams
发明人： Michael D Williams
IPC分类号： A61B17/00
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12145 , A61B17/1215 , A61B17/12154 , A61B2017/12063
摘要： A system for delivering an occlusive device includes a delivery wire assembly configured to be slidably inserted into and through the lumen of a delivery catheter, the delivery wire assembly including a delivery wire conduit defining a conduit lumen and having a conduit distal end forming a first cathode of a position detection circuit, a noble wire disposed in the conduit lumen and having a noble wire distal end forming an anode of the position detection circuit, and a core wire disposed in the conduit lumen and having a core wire distal end, the core wire distal end forming a second cathode of the position detection circuit, wherein an occlusive device is detachably coupled to the core wire distal end.
摘要翻译：用于递送闭塞装置的系统包括被配置为可滑动地插入并穿过输送导管的内腔的输送线组件，输送线组件包括限定导管腔并具有形成第一阴极的导管远端的输送线导管的位置检测电路，位于所述导管腔内的贵金属丝，具有形成所述位置检测电路的阳极的贵金属丝末端，以及设置在所述导管管腔中并具有芯线前端的芯线，所述芯线远端形成位置检测电路的第二阴极，其中闭塞装置可拆卸地联接到芯线远端。

37. 发明申请

US20110092997A1 MICRO-COIL ASSEMBLY 审中-公开
标题翻译：微型线圈组件
公开(公告)号：US20110092997A1
公开(公告)日：2011-04-21
申请号：US12627496
申请日：2009-11-30
申请人： Ho Chang KANG
发明人： Ho Chang KANG
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/12154 , A61B2017/12054
摘要： Disclosed is a micro-coil assembly including: a micro-coil unit which is inserted into an cerebral aneurysm region of a patient and prevents inflow of blood by leading the blood to clot; a coil pusher unit which is arranged adjacent to the micro-coil unit and carries the micro-coil unit to the cerebral aneurysm region of the patient; a tie which connects an end part of the micro-coil unit and the coil pusher unit; and a tensile wire which is relatively movably arranged in the coil pusher unit and coupled to the tie to tense and cut the tie when the micro-coil assembly is separated. Thus, the micro-coil assembly has a simple structure and makes a micro-coil unit and a coil-pusher unit be conveniently and accurately separated, so that the micro-coil unit can be precisely inserted in an cerebral aneurysm region, thereby efficiently meeting a surgical operation of an operator.
摘要翻译：公开了一种微线圈组件，其包括：微线圈单元，其插入到患者的脑动脉瘤区域中，并通过引导血液凝块来防止血液的流入; 线圈推动器单元，其布置成与微型线圈单元相邻并且将微型线圈单元运送到患者的脑动脉瘤区域; 连接微型线圈单元的端部和线圈推动器单元的连接件; 以及拉伸线，其相对可移动地布置在线圈推动器单元中并且当微型线圈组件被分离时联接到系带以拉紧并切断连接。因此，微型线圈组件具有简单的结构，并且可以方便，准确地分离微型线圈单元和线圈推动器单元，从而可以将微型线圈单元精确地插入到脑动脉瘤区域，从而有效地满足操作者的外科手术。

38. 发明授权

US07883526B2 Embolic coil having stretch resistant member with an attached end and an end with movement freedom 有权
标题翻译：栓塞线圈具有具有附接端部和具有移动自由度的端部的具有抗拉构件
公开(公告)号：US07883526B2
公开(公告)日：2011-02-08
申请号：US11678351
申请日：2007-02-23
申请人： Donald K. Jones , Vladimir Mitelberg , William W. Sowers
发明人： Donald K. Jones , Vladimir Mitelberg , William W. Sowers
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/1214 , A61B17/12154
摘要： A coil device is provided with a stretch resistant feature. The device includes a wound coil defining a lumen and a stretch resistant member at least partially received within the lumen. A headpiece is formed by a joining of the coil and a restrictor member, typically by plasma welding. The restrictor member is also at least partially received within the lumen and defines an aperture adapted to movably receive a portion of the stretch resistant member to allow the wound coil to stretch and elongate. The stretch resistant member includes an enlarged portion that is larger than the aperture and adapted to engage the restrictor member to prevent or resist stretching of the wound coil. The restrictor member may be provided as a separate element fixedly secured to the coil wire, or the coil wire may include one or more minor turns adapted to perform the function of the restrictor member.
摘要翻译：线圈装置具有抗拉特性。该装置包括限定内腔的缠绕线圈和至少部分地容纳在内腔内的抗拉构件。通常通过等离子体焊接，线圈和节流部件的接合形成头盔。限流器构件还至少部分地容纳在内腔内并且限定适于可移动地容纳抗拉构件的一部分以允许缠绕线圈拉伸和伸长的孔。抗拉构件包括比孔大的扩大部分，并且适于接合限制器构件以防止或阻止缠绕线圈的拉伸。限流器构件可以被设置为固定地固定到线圈线的单独元件，或者线圈线可以包括适于执行限制器构件的功能的一个或多个小匝。

39. 发明授权

US07819891B2 Stretch resistant embolic coil delivery system with spring release mechanism 有权
标题翻译：具弹簧释放机构的抗张力线栓输送系统
公开(公告)号：US07819891B2
公开(公告)日：2010-10-26
申请号：US11395924
申请日：2006-03-31
申请人： Keith Balgobin , Donald K. Jones , Vladimir Mitelberg , John H. Thinnes, Jr.
发明人： Keith Balgobin , Donald K. Jones , Vladimir Mitelberg , John H. Thinnes, Jr.
IPC分类号： A61M29/00 , A61F2/06
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12154 , A61B2017/00477 , A61B2017/00862 , A61B2017/12054
摘要： A medical device for placing an embolic device at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member slidably disposed within the lumen of the catheter. An embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes an engagement member attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. A kicker member extends from the distal end of the pusher member and is biased so as to lift the retaining ring off of the engagement member to ensure the release of the embolic device when the detachment member is withdrawn from the aperture of the engagement member.
摘要翻译：一种用于将栓塞装置放置在主体容器内的预定位置处的医疗装置，包括输送导管和可滑动地设置在导管内腔内的柔性推动器构件。栓塞装置通过机械互锁机构保持在输送导管内，该机械互锁机构包括附接到推动器构件的远端的接合构件并延伸穿过栓塞装置的近端处的保持环。分离构件延伸穿过接合构件的远端处的孔，从而将栓塞装置锁定到推动器构件上。推动器构件从推动器构件的远端延伸并且被偏压以便将保持环从接合构件提起，以确保当分离构件从接合构件的孔中取出时栓塞装置的释放。

40. 发明授权

US07799052B2 Stretch resistant embolic coil delivery system with mechanical release mechanism 有权
标题翻译：具有机械释放机制的抗拉伸栓塞线圈输送系统
公开(公告)号：US07799052B2
公开(公告)日：2010-09-21
申请号：US11471801
申请日：2006-06-21
申请人： Keith Balgobin , Vladimir Mitelberg , Dirk Tenne , John H. Thinnes, Jr.
发明人： Keith Balgobin , Vladimir Mitelberg , Dirk Tenne , John H. Thinnes, Jr.
IPC分类号： A61M29/00 , A61F2/06
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12154 , A61B2017/00477 , A61B2017/12054
摘要： A medical device for placing an embolic device at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member slidably disposed within the lumen of the catheter. An embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes an engagement member attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. A kicker tongue which is formed as an extension of a portion of the wall of the pusher member extends distally from the distal end of the pusher member and is biased so as to lift the retaining ring off of the engagement member to ensure the release of the embolic device when the detachment member is withdrawn from the aperture of the engagement member.
摘要翻译：一种用于将栓塞装置放置在主体容器内的预定位置处的医疗装置，包括输送导管和可滑动地设置在导管内腔内的柔性推动器构件。栓塞装置通过机械互锁机构保持在输送导管内，该机械互锁机构包括附接到推动器构件的远端的接合构件并延伸穿过栓塞装置的近端处的保持环。分离构件延伸穿过接合构件的远端处的孔，从而将栓塞装置锁定到推动器构件上。形成为推动器构件的壁的一部分的延伸部的推杆舌片从推动器构件的远端向远侧延伸并且被偏压以将保持环从接合构件提升以确保释放当分离构件从接合构件的孔中取出时，栓塞装置。

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