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31. 发明授权

US5614208A Methods of treatment using di-linoleoyl-mono-gamma-linolenyl glycerol 失效
标题翻译：使用二亚油酰基单一γ-亚麻酸甘油处理的方法
公开(公告)号：US5614208A
公开(公告)日：1997-03-25
申请号：US600004
申请日：1996-02-14
申请人： David F. Horrobin , Yung-Sheng Huang
发明人： David F. Horrobin , Yung-Sheng Huang
IPC分类号： A61K31/23 , A23D9/00 , A23L1/30 , A61K8/00 , A61K8/30 , A61K8/37 , A61K8/96 , A61P13/02 , A61P15/00 , A61P17/00 , A61P25/04 , A61Q5/00 , A61Q19/00 , C07C69/587 , C11B3/10 , C11B7/00 , C11D3/06 , A61K9/70 , A61K9/14 , A61K31/20 , A61K47/12
CPC分类号： A23D9/00 , A61K31/23 , C07C69/587
摘要： Atopic eczema, breast pain or premenstrual syndrome are treated by administering to a person in need of same a composition containing at least 20% di-linoleoyl-mono-gamma-linolenyl glycerol by weight.
摘要翻译：特应性湿疹，乳房疼痛或经前期综合征通过给予需要相同组合物的人治疗，所述组合物含有至少20％重量的二亚油酰基单一γ-亚麻醇甘油。

32. 发明授权

US5552150A Compostions containing di-linoleoyl-mono-gamma-linolenyl-glycerol 失效
标题翻译：含有二亚油酰 - 单-γ-亚麻油基 - 甘油的组合物
公开(公告)号：US5552150A
公开(公告)日：1996-09-03
申请号：US158986
申请日：1993-11-30
申请人： David F. Horrobin , Yung-Sheng Huang
发明人： David F. Horrobin , Yung-Sheng Huang
IPC分类号： A61K31/23 , A23D9/00 , A23L1/30 , A61K8/00 , A61K8/30 , A61K8/37 , A61K8/96 , A61P13/02 , A61P15/00 , A61P17/00 , A61P25/04 , A61Q5/00 , A61Q19/00 , C07C69/587 , C11B3/10 , C11B7/00 , C11D3/06 , A61K31/20 , A61K9/14 , A61K47/12
CPC分类号： A23D9/00 , A61K31/23 , C07C69/587
摘要： A natural or synthetic glycerol oil which comprises at least 20% by weight, preferably at least 25% of di-linoleoyl-mono-gamma-linolenyl-glycerol (DLMG), is used to supplement foods, nutritional compositions and in skin and hair care compositions.
摘要翻译：使用包含至少20重量％，优选至少25％的二亚油酰 - 单γ-亚麻油烯甘油（DLMG）的天然或合成甘油油来补充食物，营养组合物和皮肤和头发护理组合物。

33. 发明申请

US20140138960A1 Method for jump starting a vehicle 审中-公开
标题翻译：跳车启动方法
公开(公告)号：US20140138960A1
公开(公告)日：2014-05-22
申请号：US13694308
申请日：2012-11-19
申请人： Yung-Sheng Huang
发明人： Yung-Sheng Huang
IPC分类号： F02N11/08
CPC分类号： F02N11/0866 , F02N11/14
摘要： A method for jump starting a vehicle comprising causing a control unit to set a reference voltage by choosing a point from a chart plotting voltage across a starting battery versus time during a vehicle start; determining whether the voltage across a starting battery of the vehicle is less than the reference voltage; closing a switch if the determination is positive, thereby causing an external power source to supply high current to the starting battery; adding the high current and current from the starting battery to obtain a total current; and supplying the total current to a starter motor of the vehicle so as to start the vehicle. An apparatus for thus jump starting a vehicle is also disclosed.
摘要翻译：一种用于跳车起动车辆的方法，包括使得控制单元通过从车辆起动期间在起动电池两端的时间上绘制电压的图表中选择点来设定参考电压; 确定所述车辆的起动电池两端的电压是否小于所述参考电压; 如果确定为正，关闭开关，从而使外部电源向起动电池供应高电流; 从起动电池中加入高电流和电流以获得总电流; 并将总电流提供给车辆的起动电动机以起动车辆。还公开了一种用于这样跳起车辆的装置。

34. 发明申请

US20110256260A2 METHODS AND COMPOSITIONS FOR SYNTHESIS OF LONG CHAIN POLYUNSATURATD FATTY ACIDS 失效
标题翻译：用于合成长链多糖脂肪酸的方法和组合物
公开(公告)号：US20110256260A2
公开(公告)日：2011-10-20
申请号：US12414274
申请日：2009-03-30
申请人： Deborah Knutzon , Pradip Mukerji , Yung-Sheng Huang , Jennifer Thurmond , Sunita Chaudhary , Amanda Leonard
发明人： Deborah Knutzon , Pradip Mukerji , Yung-Sheng Huang , Jennifer Thurmond , Sunita Chaudhary , Amanda Leonard
IPC分类号： A23L1/30 , A23K1/18 , A23D9/00 , C07C57/02 , C11B1/00
CPC分类号： C12N9/0083 , A01K2217/05 , A23D9/00 , A23K20/158 , A23L33/12 , A23L33/40 , A61K38/00 , C12N15/81 , C12N15/8247 , C12P7/6427 , C12P7/6472
摘要： The present invention relates to fatty acid desaturases able to catalyze the conversion of oleic acid linoleic acid, linoleic acid to γ-linolenic acid, or of alpha-linolenic acid to stearidonic acid. Nucleic acid sequences encoding desaturases, nucleic acid sequences which hybridize thereto, DNA constructs comprising a desaturase gene, and recombinant host microorganism or animal expressing increased levels of a desaturase are described. Methods for desaturating a fatty acid and for producing a desaturated fatty acid by expressing increased levels of a desaturase are disclosed. Fatty acids, and oils containing them, which have been desaturated by a desaturase produced by recombinant host microorganisms or animals are provided. Pharmaceutical compositions, infant formulas or dietary supplements containing fatty acids which have been desaturated by a desaturase produced by a recombinant host microorganism or animal also are described.
摘要翻译：本发明涉及能够催化油酸亚油酸，亚油酸与γ-亚麻酸或α-亚麻酸向十八碳四烯酸的转化的脂肪酸去饱和酶。描述了编码去饱和酶的核酸序列，与其杂交的核酸序列，包含去饱和酶基因的DNA构建体和表达增加的去饱和酶水平的重组宿主微生物或动物。公开了通过表达增加的去饱和酶水平使脂肪酸去饱和并产生去饱和脂肪酸的方法。提供了通过由重组宿主微生物或动物产生的去饱和酶已经去饱和的含有它们的脂肪酸和油。还描述了通过由重组宿主微生物或动物产生的去饱和酶已经去饱和的含有脂肪酸的药物组合物，婴儿配方食品或膳食补充剂。

35. 发明申请

US20110003360A1 DELTA-6 DESATURASE AND USES THEREOF 有权
标题翻译： DELTA-6 DESATURASE及其用途
公开(公告)号：US20110003360A1
公开(公告)日：2011-01-06
申请号：US12878807
申请日：2010-09-09
申请人： Pradip Mukerji , Yung-Sheng Huang , Tapas Das , Jennifer Thurmond , Suzette L. Pereira
发明人： Pradip Mukerji , Yung-Sheng Huang , Tapas Das , Jennifer Thurmond , Suzette L. Pereira
IPC分类号： C12N9/02 , C07H21/04
CPC分类号： C12N9/0083 , C12N15/8247 , C12P7/6427 , C12P7/6472
摘要： The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., “Δ5-desaturase”) and at carbon 6 (i.e., “Δ6-desaturase”) and to uses thereof. In particular, Δ5-desaturase may be utilized, for example, in the conversion of dihomo-γ-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20:4n-3 to eicosapentaenoic acid (EPA). Delta-6 desaturase may be used, for example, in the conversion of linoleic (LA) to γ-linolenic acid (GLA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
摘要翻译：本发明涉及在碳5（即“＆Dgr.5-去饱和酶”）和碳6（即“＆Dgr; 6-去饱和酶”）上参与多不饱和脂肪酸去饱和的基因的鉴定及其用途。特别地，可以使用＆Dgr。5-去饱和酶，例如在将dihomo-γ-亚麻酸（DGLA）转化为花生四烯酸（AA）和将20:4n-3转化成二十碳五烯酸（EPA）的过程中，。 Δ-6去饱和酶可用于例如亚油酸（LA）转化成γ-亚麻酸（GLA）。由其制备的AA或多不饱和脂肪酸可以加入到药物组合物，营养组合物，动物饲料中，以及其它产品如化妆品中。

36. 发明申请

US20090265798A1 Desaturase genes and uses thereof 审中-公开
标题翻译：去饱和酶基因及其用途
公开(公告)号：US20090265798A1
公开(公告)日：2009-10-22
申请号：US11800631
申请日：2007-05-07
申请人： Pradip Mukerji , Yung-Sheng Huang , Tapas Das , Jennifer Thurmond , Suzette L. Pereira
发明人： Pradip Mukerji , Yung-Sheng Huang , Tapas Das , Jennifer Thurmond , Suzette L. Pereira
IPC分类号： A01K67/027 , C12N5/04 , C07C57/00 , A01H5/00 , C12N9/02
CPC分类号： C12N9/0083 , C12N15/8247 , C12P7/6427 , C12P7/6472
摘要： The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., “Δ5-desaturase”) and at carbon 6 (i.e., “Δ6-desaturase”) and to uses thereof. In particular, Δ5-desaturase may be utilized, for example, in the conversion of dihomo-γ-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20:4n-3 to eicosapentaenoic acid (EPA). Delta-6 desaturase may be used, for example, in the conversion of linoleic (LA) to γ-linolenic acid (GLA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
摘要翻译：本发明涉及鉴定参与碳5（即“Δ5-去饱和酶”）和碳6（即“Δ6-去饱和酶”）的多不饱和脂肪酸的去饱和的基因及其用途。特别地，可以使用Δ5-去饱和酶，例如将dihomo-γ-亚麻酸（DGLA）转化为花生四烯酸（AA）和将20:4n-3转化成二十碳五烯酸（EPA）。 Δ-6去饱和酶可用于例如亚油酸（LA）转化为γ-亚麻酸（GLA）。由其制备的AA或多不饱和脂肪酸可以加入到药物组合物，营养组合物，动物饲料中，以及其它产品如化妆品中。

37. 发明授权

US07531347B1 Methods and compositions for synthesis of long chain polyunsaturated fatty acids 失效
标题翻译：用于合成长链多不饱和脂肪酸的方法和组合物
公开(公告)号：US07531347B1
公开(公告)日：2009-05-12
申请号：US09367013
申请日：1998-04-10
申请人： Deborah Knutzon , Pradip Mukerji , Yung-Sheng Huang , Jennifer Thurmond , Sunita Chaudhary , Amanda Eun-Yeong Leonard
发明人： Deborah Knutzon , Pradip Mukerji , Yung-Sheng Huang , Jennifer Thurmond , Sunita Chaudhary , Amanda Eun-Yeong Leonard
IPC分类号： C12N1/16 , C07H21/04
CPC分类号： C12N9/0083 , A01K2217/05 , A23D9/00 , A23K20/158 , A23L33/12 , A23L33/40 , A61K38/00 , C12N15/81 , C12N15/8247 , C12P7/6427 , C12P7/6472
摘要： The present invention relates to fatty acid desaturases able to catalyze the conversion of oleic acid to linoleic acid, linoleic acid to γ-linolenic acid, or of alpha-linolenic acid to stearidonic acid. Nucleic acid sequences encoding desaturases, nucleic acid sequences which hybridize thereto, DNA constructs comprising a desaturase gene, and recombinant host microorganism or animal expressing increased levels of a desaturase are described. Methods for desaturating a fatty acid and for producing a desaturated fatty acid by expressing increased levels of a desaturase are disclosed. Fatty acids, and oils containing them, which have been desaturated by a desaturase produced by recombinant host microorganisms or animals are provided. Pharmaceutical compositions, infant formulas or dietary supplements containing fatty acids which have been desaturated by a desaturase produced by a recombinant host microorganism or animal also are described.
摘要翻译：本发明涉及能够催化油酸向亚油酸，亚麻油酸，γ-亚麻酸或α-亚麻酸转化成十八碳四烯酸的脂肪酸去饱和酶。描述了编码去饱和酶的核酸序列，与其杂交的核酸序列，包含去饱和酶基因的DNA构建体和表达增加的去饱和酶水平的重组宿主微生物或动物。公开了通过表达增加的去饱和酶水平使脂肪酸去饱和并产生去饱和脂肪酸的方法。提供了通过由重组宿主微生物或动物产生的去饱和酶已经去饱和的含有它们的脂肪酸和油。还描述了通过由重组宿主微生物或动物产生的去饱和酶已经去饱和的含有脂肪酸的药物组合物，婴儿配方食品或膳食补充剂。

38. 发明授权

US07456270B2 Δ6-desaturase genes and uses thereof 失效
标题翻译： Delta6-去饱和酶基因及其用途
公开(公告)号：US07456270B2
公开(公告)日：2008-11-25
申请号：US10931626
申请日：2004-09-01
申请人： Pradip Mukerji , Yung-Sheng Huang , Amanda E. Leonard , Suzette L. Pereira , Jennifer M. Thurmond
发明人： Pradip Mukerji , Yung-Sheng Huang , Amanda E. Leonard , Suzette L. Pereira , Jennifer M. Thurmond
IPC分类号： C07H21/24 , C12P21/06 , C12N15/00 , C12N5/04
CPC分类号： C12N15/8247 , C12N9/0083
摘要： The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 6 (i.e., “Δ6-desaturase”). In particular, Δ6-desaturase may be utilized, for example, in the conversion of linoleic acid to γ-linolenic acid and in the conversion of α-linolenic acid stearidonic acid. The polyunsaturated fatty acids produced by use of the enzyme may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
摘要翻译：本发明涉及鉴定参与碳6多不饱和脂肪酸脱饱和基因（即“Δ6-去饱和酶”）的基因。特别地，可以使用Δ6-去饱和酶，例如，将亚油酸转化为γ-亚麻酸和在α-亚麻酸十八碳四烯酸的转化中。通过使用酶产生的多不饱和脂肪酸可以加入到药物组合物，营养组合物，动物饲料中，以及其它产品如化妆品中。

39. 发明授权

US07375205B2 Elongase genes and uses thereof 有权
标题翻译：延长酶基因及其用途
公开(公告)号：US07375205B2
公开(公告)日：2008-05-20
申请号：US10912446
申请日：2004-08-05
申请人： Pradip Mukerji , Amanda Eun-Yeong Leonard , Yung-Sheng Huang , Suzette L Pereira
发明人： Pradip Mukerji , Amanda Eun-Yeong Leonard , Yung-Sheng Huang , Suzette L Pereira
IPC分类号： C07H21/04 , C12N9/00 , C12N1/20 , C12N15/00 , C12N5/04 , C12N1/15 , C12P21/00
CPC分类号： A23D9/00 , A01K2217/05 , A23K20/158 , A61K8/361 , A61K8/606 , A61K8/64 , A61K31/202 , A61K38/00 , A61K2800/86 , A61Q19/00 , C12N9/1029 , C12N15/8247 , C12P7/6427 , C12P7/6472
摘要： The subject invention relates to the identification of several genes involved in the elongation of polyunsaturated fatty acids (i.e., “elongases”) and to uses thereof. At least two of these genes are also involved in the elongation of monounsaturated fatty acids. In particular, elongase is utilized in the conversion of gamma linolenic acid (GLA) to dihomogamma linolenic acid (DGLA) and in the conversion of AA to adrenic acid (ADA), or eicosapentaenoic acid (EPA) to ω3-docosapentaenoic acid (DPA). DGLA may be utilized in the production of polyunsaturated fatty acids, such as arachidonic acid (AA), docosahexaenoic acid (DHA), EPA, adrenic acid, ω6-docosapentaenoic acid or ω3-docosapentaenoic acid which may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
摘要翻译：本发明涉及多参与多不饱和脂肪酸（即“延伸酶”）延伸的几个基因的鉴定及其应用。这些基因中至少有两个也参与单不饱和脂肪酸的延伸。特别地，延长酶用于将γ-亚麻酸（GLA）转化为二亚麻酸（DGLA）和将AA转化为肾上腺素（ADA）或二十碳五烯酸（EPA）转化为ω-二十二碳五烯酸（DPA）。 DGLA可用于生产多不饱和脂肪酸，例如花生四烯酸（AA），二十二碳六烯酸（DHA），EPA，肾上腺素，ω6-二十二碳五烯酸或ω3-二十二碳五烯酸，其可加入到药物组合物中，营养组合物，动物饲料，以及化妆品等其他产品。

40. 发明申请

US20080094069A1 Method and apparatus for monitoring the condition of a battery by measuring its internal resistance 有权
标题翻译：通过测量电池的内阻来监测电池状态的方法和装置
公开(公告)号：US20080094069A1
公开(公告)日：2008-04-24
申请号：US11984669
申请日：2007-11-20
申请人： Yung-Sheng Huang
发明人： Yung-Sheng Huang
IPC分类号： G01R31/36 , H01M10/48
CPC分类号： G01R31/3662 , G01R31/3648 , G01R31/3693
摘要： A method for evaluating the condition of a battery comprises coupling a first power transistor as or as part of a first external load in series with the battery, coupling a second power transistor as or as part of a second external load in series with the battery, and conducting each power transistor to draw a transient large current from the battery while sampling the voltage across the battery and voltage across the load, from which the internal resistance of the battery can be determined. The internal resistance of the battery can then be compared with a predetermined nominal value to issue a warning if the battery is weak. The invention enables, for example, a driver to correctly know the actual condition of an automobile battery in substantially real time while consuming a minimum amount of power.
摘要翻译：一种用于评估电池状态的方法包括将第一功率晶体管与第一外部负载串联耦合作为电池，或者作为与电池串联的第二外部负载的一部分的第二功率晶体管，并且对每个功率晶体管进行引导以从电池中抽取瞬时大电流，同时对电池两端的电压进行采样并且跨越负载进行电压测量，从而确定电池的内部电阻。然后可以将电池的内部电阻与预定的标称值进行比较，以在电池较弱时发出警告。本发明使得例如驾驶员能够在消耗最小功率的情况下基本上实时地正确地知道汽车电池的实际状况。

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