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31. 发明申请

US20060116344A1 Remedy and preventive for diseases caused by NF-kB 审中-公开
标题翻译：补救和预防由NF-kB引起的疾病
公开(公告)号：US20060116344A1
公开(公告)日：2006-06-01
申请号：US11324230
申请日：2006-01-04
申请人： Ryuichi Morishita , Toshio Ogiwara , Toshiko Sugimoto , Kazuhiro Maeda , Ikuo Kawamura , Toshiyuki Chiba
发明人： Ryuichi Morishita , Toshio Ogiwara , Toshiko Sugimoto , Kazuhiro Maeda , Ikuo Kawamura , Toshiyuki Chiba
IPC分类号： A61K48/00 , C07H21/02
CPC分类号： A61K31/00 , A61K38/00 , A61K48/005 , C12N15/113 , C12N2310/13 , C12N2310/315
摘要： Administration of a decoy, i.e. a compound which specifically antagonizes the nucleic acid domain to which NF-κB is bound, is effective in the treatment and prevention of diseases caused by the transcriptional regulatory factor NF-κB, such as ischemic diseases, inflammatory diseases, autoimmune diseases, cancer metastasis and invasion, and cachexia.
摘要翻译：施用诱饵，即特异性拮抗NF-κB结合的核酸结构域的化合物在治疗和预防由转录调节因子NF-κB引起的疾病中是有效的，例如缺血性疾病，炎性疾病，自身免疫性疾病，癌症转移和侵袭以及恶病质。

32. 发明授权

US07034795B2 Matrix image display device 失效
公开(公告)号：US07034795B2
公开(公告)日：2006-04-25
申请号：US10208757
申请日：2002-08-01
申请人： Kazuhiro Maeda , Hajime Washio , Yasushi Kubota
发明人： Kazuhiro Maeda , Hajime Washio , Yasushi Kubota
IPC分类号： G06G3/36
CPC分类号： G09G3/3648 , G09G3/3614 , G09G2310/021 , G09G2310/0251 , G09G2320/0209 , G09G2340/0414
摘要： The scanning signal line driving circuit sequentially carries out active driving with respect to each set of a certain number of scanning signal lines which are adjacent to each other in a vertical direction, and when carrying out an actual writing with respect to a first set of a certain number of pixel lines adjacent to each other in the vertical direction, carries out pre-charging with respect to a second set of the certain number of pixel lines to which the actual writing is carried out next with a potential of a same polarity as that of the first set of the certain number of pixel lines. In this manner, it is possible to provide a matrix image display device with no irregularities in display quality and is capable of matching the apparent vertical resolution of the device to that of the image source, when using an image signal of vertical resolution lower than the maximum physical vertical resolution of the device.

33. 发明授权

US06989401B2 Sulfonic acid derivatives of hydroxamic acids and their use as medicinal products 失效
公开(公告)号：US06989401B2
公开(公告)日：2006-01-24
申请号：US10333266
申请日：2001-07-19
申请人： Kazuhiro Maeda , Shuji Sonda , Tadahiro Takemoto , Tomokazu Goto , Fujio Kobayashi , Masahiko Kajii , Naruyasu Komorita , Fumihiro Hirayama
发明人： Kazuhiro Maeda , Shuji Sonda , Tadahiro Takemoto , Tomokazu Goto , Fujio Kobayashi , Masahiko Kajii , Naruyasu Komorita , Fumihiro Hirayama
IPC分类号： A61K31/403 , C07D207/408
CPC分类号： C07D209/48 , A61K31/185 , C07C309/11 , C07C309/15 , C07C309/51
摘要： The present invention relates to a novel sulfonic acid derivative of hydroxamic acid or a pharmacologically acceptable salt thereof. More particularly, the present invention relates to a sulfonic acid derivative of hydroxamic acid or a pharmacologically acceptable salt thereof, which is useful as an inhibitor of lipopolysaccharides (LPS). In addition, the present invention relates to a novel intermediate compound useful for the synthesis of this sulfonic acid derivative of hydroxamic acid.

34. 发明授权

US06836269B2 Precharge circuit and image display device using the same 有权
标题翻译：预充电电路和使用其的图像显示装置
公开(公告)号：US06836269B2
公开(公告)日：2004-12-28
申请号：US09795658
申请日：2001-02-28
申请人： Kazuhiro Maeda , Hajime Washio , Yasushi Kubota , Yasuyoshi Kaise , Michael James Brownlow , Graham Andrew Cairns
发明人： Kazuhiro Maeda , Hajime Washio , Yasushi Kubota , Yasuyoshi Kaise , Michael James Brownlow , Graham Andrew Cairns
IPC分类号： G09G500
CPC分类号： G09G3/3688 , G09G2310/0248 , G09G2310/0289 , G09G2330/021
摘要： A precharge control circuit constituted by (1) a latch circuit mounted in a precharge circuit and (2) a level shifter circuit of a current drive type controlled through an output of the latch circuit is included. The precharge control circuit changes the latch circuit to an active state to cause the level shifter circuit of a current drive type to operate only during a precharge period and also during immediately preceding and succeeding periods, and outside these periods, changes the latch circuit in a non-active state and the level shifter circuit of a current drive type in an operating state to save power consumption in the level shifter circuit. This enables a low-power-consuming precharge circuit, as well as a low-power-consuming image display device with a high quality display capability, to be offered.
摘要翻译：一种预充电控制电路，包括：（1）安装在预充电电路中的锁存电路和（2）通过锁存电路的输出控制的电流驱动型电平移位电路。预充电控制电路将锁存电路改变为有效状态，使得电流驱动类型的电平移动电路仅在预充电期间以及在紧接之前和之后周期期间操作，并且在这些周期之外，将锁存电路改变为非活动状态和电流驱动类型的电平移位器电路，以在电平移位器电路中节省功耗。这使得能够提供低功耗预充电电路以及具有高质量显示能力的低功耗图像显示装置。

35. 发明授权

US06805214B2 Breather system and straddle-type four wheeled all terrain vehicle comprising breather system 失效
标题翻译：呼吸系统和跨骑式四轮全地形车辆包括呼吸系统
公开(公告)号：US06805214B2
公开(公告)日：2004-10-19
申请号：US10059941
申请日：2002-01-28
申请人： Kazuhiro Maeda , Gaku Yoshimura
发明人： Kazuhiro Maeda , Gaku Yoshimura
IPC分类号： B60K1500
CPC分类号： B62K5/01 , B62J35/00 , Y10S180/908
摘要： Disclosed is a breather system for a fuel tank reliably performing a function of a breather when a vehicle is inclined to the right or to the left and a straddle-type four wheeled all terrain vehicle comprising the breather system in which the fuel tank is provided below a seat, and a fuel inlet and a tank cap covering the fuel inlet is protruded from a rear fender laterally of the seat. The breather system has two breather openings provided in the fuel tank, breather hoses respectively connected to the breather openings, a T-shape joint integrally connecting the breather hoses, and a check valve connected to an ambient side of the T-shape joint, and the two breather openings are provided on the right and left sides of the fuel tank so as to be spaced apart from each other.
摘要翻译：公开了一种用于当车辆向右或向左倾斜时可靠地执行呼吸器功能的燃料箱的呼吸器系统和包括在其中设置燃料箱的通气系统的跨骑式四轮全地形车辆座椅以及覆盖燃料入口的燃料入口和罐盖从座椅横向的后挡泥板突出。通气系统具有设置在燃料箱中的两个通气孔，分别连接到通气孔的通气软管，连接通气软管的T形接头和连接到T形接头的环境侧的止回阀，以及两个通气孔设置在燃料箱的右侧和左侧，以便彼此间隔开。

36. 发明授权

US06724363B1 Two-way shift register and image display device using the same 有权
公开(公告)号：US06724363B1
公开(公告)日：2004-04-20
申请号：US09568889
申请日：2000-05-11
申请人： Masakazu Satoh , Yasushi Kubota , Hajime Washio , Kazuhiro Maeda , Michael James Brownlow , Graham Andrew Cairns
发明人： Masakazu Satoh , Yasushi Kubota , Hajime Washio , Kazuhiro Maeda , Michael James Brownlow , Graham Andrew Cairns
IPC分类号： G09G336
CPC分类号： G11C19/00 , G09G3/3674 , G09G3/3685 , G09G2310/0283 , G09G2310/0289 , G09G2330/021 , G11C19/28
摘要： A shift register is provided with a shift register section composed of a plurality of stages of flip-flops that operate in synchronization with a clock signal, and level shifters for boosting a start signal lower than a driving voltage and for applying the same to both ends of the shift register section, and the shift register is capable of switching the shift direction in accordance with the switching signal. The foregoing level shifters are current-driving-type level shifters that can operate even in the case where the transistor characteristics are inferior or in the case of fast operations, and that can carry out level shifting even with a start signal having a small amplitude. Furthermore, the foregoing level shifters are provided at both ends of the shift register section, respectively, and one of the same stops operating in accordance with a switching signal, so that consumed power should decrease. Consequently, there can be provided a shift register that is capable of shifting in two directions, that can normally operate even with an input signal having a small amplitude, and that therefore consumes less electric power.

37. 发明授权

US06559824B1 Matrix type image display device 有权
标题翻译：矩阵式图像显示装置
公开(公告)号：US06559824B1
公开(公告)日：2003-05-06
申请号：US09666376
申请日：2000-09-20
申请人： Yasushi Kubota , Hajime Washio , Kazuhiro Maeda , Graham Andrew Cairns , Michael James Brownlow
发明人： Yasushi Kubota , Hajime Washio , Kazuhiro Maeda , Graham Andrew Cairns , Michael James Brownlow
IPC分类号： G09G336
CPC分类号： G09G3/3688 , G09G3/20 , G09G3/3677 , G09G2300/0408 , G09G2310/0232 , G09G2310/0248 , G09G2310/0289 , G09G2330/021
摘要： A matrix type image display device has a structure in which the internal states of all of shift registers (the outputs of flip-flops included in the shift registers) in a scanning signal line drive circuit and data signal line drive circuit are made inactive by the use of an initializing signal generated by a NAND gate based on a combination of signals, which do not affect a displayed image, from a control circuit. With this structure, since the shift registers are initialized when power is supplied, it is possible to prevent an indefinite state when power is supplied. Therefore, by selectively inputting signals (such as clock signals) for controlling the shift registers, it is possible to prevent an excessive increase in the signal line load. Consequently, the operation of the image display device can be stabilized. Moreover, it is not necessary to improve the drive ability of an external IC incorporating the control circuit and the supply ability of a power supply circuit, thereby achieving a reduction in the cost and power consumption of the external IC.
摘要翻译：矩阵型图像显示装置具有这样的结构，其中扫描信号线驱动电路和数据信号线驱动电路中的所有移位寄存器（包括在移位寄存器中的触发器的输出）的内部状态由基于不影响显示图像的信号的组合，从NAND门产生的初始化信号从控制电路使用。利用这种结构，由于在供电时初始化了移位寄存器，所以可以在供电时防止不确定的状态。因此，通过选择性地输入用于控制移位寄存器的信号（例如时钟信号），可以防止信号线负载的过度增加。因此，能够使图像显示装置的动作稳定。此外，不需要提高包含控制电路的外部IC的驱动能力和电源电路的供给能力，从而实现了外部IC的成本和功耗的降低。

38. 发明授权

US06262033B1 Remedy for diseases associated with NF-&kgr;B 失效
标题翻译：补救与NF-κB相关的疾病
公开(公告)号：US06262033B1
公开(公告)日：2001-07-17
申请号：US08945805
申请日：1998-01-06
申请人： Ryuichi Morishita , Toshio Ogiwara , Toshiko Sugimoto , Kazuhiro Maeda , Ikuo Kawamura , Toshiyuki Chiba
发明人： Ryuichi Morishita , Toshio Ogiwara , Toshiko Sugimoto , Kazuhiro Maeda , Ikuo Kawamura , Toshiyuki Chiba
IPC分类号： A61K4800
CPC分类号： A61K31/00 , A61K38/00 , A61K48/005 , C12N15/113 , C12N2310/13 , C12N2310/315
摘要： Administration of a decoy, i.e. a compound which specifically antagonizes the nucleic acid domain to which NF-&kgr;B is bound, is effective in the treatment and prevention of diseases caused by the transcriptional regulatory factor NF-&kgr;B, such as ischemic diseases, inflammatory diseases, autoimmune diseases, cancer metastasis and invasion, and cachexia.
摘要翻译：施用诱饵，即特异性拮抗NF-κB结合的核酸结构域的化合物在治疗和预防由转录调节因子NF-κB引起的疾病中是有效的，例如缺血性疾病，炎性疾病，自身免疫性疾病，癌症转移和侵袭以及恶病质。

39. 发明授权

US4990507A N-containing heterocyclic compounds, and composition comprising the same 失效
标题翻译：含氮杂环化合物及其组合物
公开(公告)号：US4990507A
公开(公告)日：1991-02-05
申请号：US294743
申请日：1989-01-09
申请人： Takao Takaya , Hisashi Takasugi , Kimio Esumi , Atsushi Kuno , Hiroyoshi Sakai , Kazuhiro Maeda , Yoshie Sakamoto
发明人： Takao Takaya , Hisashi Takasugi , Kimio Esumi , Atsushi Kuno , Hiroyoshi Sakai , Kazuhiro Maeda , Yoshie Sakamoto
IPC分类号： C07D213/26 , C07D213/30 , C07D213/36 , C07D213/75 , C07D213/80 , C07D213/82 , C07D237/08 , C07D237/24 , C07D413/12 , C07D471/04 , C07D401/12 , A61K31/44
CPC分类号： C07D213/30 , C07D213/26 , C07D213/36 , C07D213/75 , C07D213/80 , C07D213/82 , C07D237/08 , C07D237/24 , C07D413/12 , C07D471/04
摘要： The invention relates to a pharmaceutical composition as a therapeutic agent for ischemic disease comprising a compound of the formula ##STR1## wherein R.sup.1 is carbamoyl substituted with morpholino (lower) alkyl, thiomorpholino(lower)alkyl or lower alkylamino(lower)alkyl; or ureido substituted with lower alkylamino(lower)alkyl; andR.sup.2 is phenyl substituted with nitro, andR.sup.4 is lower alkyl; orR.sup.2 is lower alkyl, andR.sup.4 is phenyl substituted with nitro;with proviso that R.sup.1 is carbamoyl substituted with thiomorpholino(lower)alkyl or lower alkylamino(lower)alkyl; or ureido substituted with lower alkylamino(lower)alkyl when R.sup.4 is lower alkyl; or its salt, as an active ingredient, in association with a pharmaceutically acceptable, substantially nontoxic carrier or excipient.
摘要翻译：本发明涉及作为缺血性疾病治疗剂的药物组合物，其包含下式化合物其中R 1是被吗啉代（低级）烷基，硫代吗啉代（低级）烷基或低级烷基氨基（低级）烷基取代的氨基甲酰基）或被低级烷基氨基（低级）烷基取代的脲基; R2是被硝基取代的苯基，R4是低级烷基; 或R 2为低级烷基，R 4为被硝基取代的苯基; 条件是R1是被硫代吗啉代（低级）烷基或低级烷基氨基（低级）烷基取代的氨基甲酰基; 或当R 4为低级烷基时被低级烷基氨基（低级）烷基取代的脲基; 或其盐作为活性成分，与药学上可接受的，基本上无毒的载体或赋形剂结合。

40. 发明授权

US09146635B2 Touch panel equipped display device and control method for same 有权
标题翻译：触摸面板配置的显示设备和控制方法相同
公开(公告)号：US09146635B2
公开(公告)日：2015-09-29
申请号：US14110769
申请日：2012-04-09
申请人： Yousuke Nakagawa , Kazuhiro Maeda
发明人： Yousuke Nakagawa , Kazuhiro Maeda
IPC分类号： G06F3/041 , G09G3/36 , G06F3/044 , G02F1/1333
CPC分类号： G06F3/0412 , G02F1/13338 , G06F3/0416 , G06F3/044 , G09G3/3648 , G09G3/3688 , G09G2310/0297 , G09G2310/08
摘要： Provided is a touch panel-equipped display device (10) including: a touch panel (14); a display part (12) including source bus lines (25); a source bus line potential switching part that switches the potential of each source bus line (25) in a source bus line potential switching period (54) that is a partial period of a vertical blanking period (51); and a sensing part that performs sensing for a touch panel in a sensing period (53) that is a period in the vertical blanking period (51) other than the partial period.
摘要翻译：提供了一种具有触摸面板的显示装置（10），包括：触摸面板（14）; 包括源极总线（25）的显示部分（12）; 源极总线线路电势切换部，其将源极总线线路电位切换期间（54）中的每个源极总线（25）的电位切换为垂直消隐期间（51）的部分期间; 以及感测部，其在除了所述部分期间之外的所述垂直消隐期间（51）的周期的感测期间（53）中对触摸面板进行感测。

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