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31. 发明申请

US20070032738A1 Adaptive patient training routine for biological interface system 审中-公开
标题翻译：生物界面系统的适应性患者训练程序
公开(公告)号：US20070032738A1
公开(公告)日：2007-02-08
申请号：US11315226
申请日：2005-12-23
申请人： J. Flaherty , Mijail Serruya , Daniel Morris , Abraham Caplan , Maryam Saleh , John Donoghue
发明人： J. Flaherty , Mijail Serruya , Daniel Morris , Abraham Caplan , Maryam Saleh , John Donoghue
IPC分类号： A61B5/04
CPC分类号： A61B5/04001 , A61B5/0482 , G06F3/015
摘要： Various embodiments of a biological interface system and related methods are disclosed. The system may comprise a sensor comprising a plurality of electrodes for detecting multicellular signals emanating from one or more living cells of a patient and a processing unit configured to receive the multicellular signals from the sensor and process the multicellular signals to produce a processed signal. The processing unit may be configured to transmit the processed signal to a controlled device that is configured to receive the processed signal. The system is configured to perform an integrated patient training routine to generate one or more system configuration parameters that are used by the processing unit to produce the processed signal.
摘要翻译：公开了生物界面系统和相关方法的各种实施例。该系统可以包括传感器，其包括用于检测从患者的一个或多个活细胞发出的多细胞信号的多个电极和被配置为从传感器接收多细胞信号并处理多细胞信号以产生经处理的信号的处理单元。处理单元可以被配置为将经处理的信号发送到被配置为接收经处理的信号的受控设备。该系统被配置为执行综合的患者训练程序，以产生一个或多个系统配置参数，该系统配置参数由处理单元用于产生经处理的信号。

32. 发明申请

US20060189901A1 Biological interface system with surrogate controlled device 审中-公开
标题翻译：具有替代控制装置的生物界面系统
公开(公告)号：US20060189901A1
公开(公告)日：2006-08-24
申请号：US11320711
申请日：2005-12-30
申请人： J. Flaherty , Abraham Caplan
发明人： J. Flaherty , Abraham Caplan
IPC分类号： A61B5/103
CPC分类号： G06F3/015 , A61F2/50 , A61F2/68 , A61F2002/704 , A61F2002/7615 , G06N3/061 , G09B19/00 , G09B23/28
摘要： Various embodiments of a biological interface system and related methods are disclosed. The system may include a sensor comprising a plurality of electrodes for detecting multicellular signals emanating from one or more living cells of a patient, and a processing unit configured to receive the multicellular signals from the sensor and process the multicellular signals to produce a processed signal. The processing unit may be configured to transmit the processed signal to a controlled device. The system further includes a first controlled device configured to receive the processed signal, and a second controlled device configured to receive the processed signal. The first controlled device may provide feedback to the patient to improve control of the second controlled device.
摘要翻译：公开了生物界面系统和相关方法的各种实施例。该系统可以包括传感器，其包括用于检测从患者的一个或多个活细胞发出的多细胞信号的多个电极，以及处理单元，被配置为从传感器接收多细胞信号并处理多细胞信号以产生经处理的信号。处理单元可以被配置为将经处理的信号发送到受控设备。该系统还包括被配置为接收经处理的信号的第一受控设备和被配置为接收经处理的信号的第二受控设备。第一受控装置可以向患者提供反馈以改善对第二受控装置的控制。

33. 发明申请

US20060167530A1 Patient training routine for biological interface system 有权
标题翻译：生物界面系统的患者训练程序
公开(公告)号：US20060167530A1
公开(公告)日：2006-07-27
申请号：US11315225
申请日：2005-12-23
申请人： J. Flaherty , Mijail Serruya , Daniel Morris , Abraham Caplan , Maryam Saleh , John Donoghue
发明人： J. Flaherty , Mijail Serruya , Daniel Morris , Abraham Caplan , Maryam Saleh , John Donoghue
IPC分类号： A61N1/18
CPC分类号： A61B5/04001 , A61B5/0482 , G06F3/015
摘要： Various embodiments of a biological interface system and related methods are disclosed. The system may comprise a sensor comprising a plurality of electrodes for detecting multicellular signals emanating from one or more living cells of a patient and a processing unit configured to receive the multicellular signals from the sensor and process the multicellular signals to produce a processed signal. The processing unit may be configured to transmit the processed signal to a controlled device that is configured to receive the processed signal. The system is configured to perform an integrated patient training routine to generate one or more system configuration parameters that are used by the processing unit to produce the processed signal.
摘要翻译：公开了生物界面系统和相关方法的各种实施例。该系统可以包括传感器，其包括用于检测从患者的一个或多个活细胞发出的多细胞信号的多个电极和被配置为从传感器接收多细胞信号并处理多细胞信号以产生经处理的信号的处理单元。处理单元可以被配置为将经处理的信号发送到被配置为接收经处理的信号的受控设备。该系统被配置为执行综合的患者训练程序，以产生一个或多个系统配置参数，该系统配置参数由处理单元用于产生经处理的信号。

34. 发明申请

US20060058627A1 Biological interface systems with wireless connection and related methods 审中-公开
标题翻译：具有无线连接和相关方法的生物界面系统
公开(公告)号：US20060058627A1
公开(公告)日：2006-03-16
申请号：US11201283
申请日：2005-08-11
申请人： J. Flaherty , John Donoghue
发明人： J. Flaherty , John Donoghue
IPC分类号： A61B5/05
CPC分类号： G09B21/00 , A61B5/0017 , A61B5/0031 , A61B5/04001 , A61B5/0476 , A61B5/0478 , A61B5/0488 , A61B5/0496 , A61B2560/0219 , A61B2560/0271 , A61N1/08 , A61N1/36003 , A61N1/36082 , A61N1/361 , G16H40/40 , G16H40/63
摘要： Various embodiments of a biological interface system and their related methods are disclosed. A biological interface system may include a sensor including a plurality of electrodes configured to detect multicellular signals emanating from one or more living cells of a patient and a processing unit configured to receive the multicellular signals from the sensor, to process the multicellular signals to produce processed signals, and to transmit the processed signals. The system may also include a controlled device configured to receive the processed signals from the processing unit. The processing unit may include a processing unit first portion and a processing unit second portion, where the processing unit first portion is implanted under the scalp on the skull of the patient, and the processing unit second portion is placed above the scalp of the patient at a location proximal to the processing unit first portion.
摘要翻译：公开了生物界面系统的各种实施例及其相关方法。生物界面系统可以包括传感器，其包括被配置成检测从患者的一个或多个活细胞发出的多细胞信号的多个电极和被配置为从传感器接收多细胞信号的处理单元，以处理多细胞信号以产生经处理信号，并传送经处理的信号。该系统还可以包括被配置为从处理单元接收经处理的信号的受控设备。处理单元可以包括处理单元第一部分和处理单元第二部分，其中处理单元第一部分植入患者头骨上的头皮下，并且处理单元第二部分放置在患者的头皮上方位于处理单元第一部分附近的位置。

35. 发明申请

US20050273890A1 Neural interface system and method for neural control of multiple devices 审中-公开
标题翻译：神经接口系统及多器件神经控制方法
公开(公告)号：US20050273890A1
公开(公告)日：2005-12-08
申请号：US11194544
申请日：2005-08-02
申请人： J. Flaherty , L. Capachione , Daniel Morris , Abraham Caplan , Maryam Saleh , K. Guillory
发明人： J. Flaherty , L. Capachione , Daniel Morris , Abraham Caplan , Maryam Saleh , K. Guillory
IPC分类号： A61B5/00 , A61B5/04 , B25J11/00 , G06K9/46
CPC分类号： A61B5/0031 , A61B5/04001 , A61B2560/0223 , A61B2560/045 , A61B2562/08
摘要： A system and method for a neural interface system with a unique identification code includes a sensor including a plurality of electrodes to detect multicellular signals, an processing unit to process the signals from the sensor into a suitable control signal for a controllable device such as a computer or prosthetic limb. The unique identification code is embedded in one or more discrete components of the system. Internal and external system checks for compatibility and methods of ensuring safe and effective performance of a system with detachable components are also disclosed.
摘要翻译：一种用于具有唯一识别码的神经接口系统的系统和方法包括：传感器，包括用于检测多细胞信号的多个电极;处理单元，用于将来自传感器的信号处理成用于诸如计算机之类的可控设备的合适的控制信号或假肢。唯一的识别码嵌入在系统的一个或多个分立组件中。还公开了内部和外部系统检查兼容性以及确保具有可拆卸部件的系统的安全和有效性能的方法。

36. 发明申请

US20050171512A1 DEVICES, SYSTEMS AND METHODS FOR PATIENT INFUSION 审中-公开
标题翻译：用于患者输注的装置，系统和方法
公开(公告)号：US20050171512A1
公开(公告)日：2005-08-04
申请号：US10904960
申请日：2004-12-07
申请人： J. Flaherty
发明人： J. Flaherty
IPC分类号： A61M5/00 , A61K9/22 , A61M5/14 , A61M5/142 , A61M5/168 , A61M37/00
CPC分类号： A61M5/14248 , A61M5/16809 , A61M5/16813 , A61M37/00 , A61M2005/1403 , A61M2005/1405 , A61M2005/14268 , A61M2205/35 , A61M2205/3569 , A61M2205/50 , A61M2205/6072 , A61M2209/01
摘要： A method for transcutaneously delivering fluid to a patient including providing at least one disposable infusion pump, wherein the pump includes a housing adapted to be mounted on a patient's skin, a transcutaneous patient access tool for extending through the housing and providing transcutaneous access to the patient, a reservoir prefilled with a therapeutic fluid, a dispenser for causing fluid from the reservoir to flow to the transcutaneous patient access tool, a processor connected to the dispenser and programmed to cause a flow of fluid from the reservoir to the transcutaneous patient access tool based on flow instructions, and a wireless receiver connected to the processor for receiving flow instructions from a remote controller and for delivering the flow instructions to the processor.
摘要翻译：一种用于向患者经皮递送流体的方法，包括提供至少一个一次性输注泵，其中所述泵包括适于安装在患者皮肤上的壳体，经皮患者进入工具，用于延伸穿过所述外壳并提供对患者的经皮通路预先填充有治疗流体的储存器，用于使来自储存器的流体流动到经皮患者通路工具的分配器，连接到分配器的处理器，并被编程为使流体从储存器流动到经皮患者入口工具以及连接到处理器的无线接收器，用于从远程控制器接收流指令并将流指令传送到处理器。

37. 发明申请

US20050090748A1 Methods and apparatus for acute or chronic delivery of substances or apparatus to extravascular treatment sites 有权
标题翻译：将物质或器械急性或慢性传播至血管外治疗部位的方法和装置
公开(公告)号：US20050090748A1
公开(公告)日：2005-04-28
申请号：US10458153
申请日：2003-06-10
申请人： Joshua Makower , Theodore Lamson , J. Flaherty , John Reggie , John Chang , Joseph Catanese , David Tholfsen
发明人： Joshua Makower , Theodore Lamson , J. Flaherty , John Reggie , John Chang , Joseph Catanese , David Tholfsen
IPC分类号： A61M31/00 , A61B17/00 , A61B17/12 , A61B18/24 , A61M5/14 , A61M25/00 , A61M25/01 , A61M25/06 , A61B8/14
CPC分类号： A61M25/065 , A61B17/00491 , A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12122 , A61B17/12136 , A61B17/12186 , A61B18/24 , A61B2017/00243 , A61B2017/00247 , A61B2017/00575 , A61B2018/00392 , A61M25/0069 , A61M25/0084 , A61M25/0102 , A61M2025/018
摘要： Methods and apparatus for delivery of substances or apparatus to target sites located outside blood vessels within the body of a human or animal patient. A vessel wall penetrating catheter is inserted into the vasculature, positioned and oriented within a blood vessel near the target extravascular site and a penetrator is advanced from the catheter so as to penetrate outwardly through the wall of the blood vessel in the direction of the target site. Thereafter, a delivery catheter is passed through a lumen of the penetrator to the target site. A desired substance or apparatus is then delivered to or obtained from the target site. In some applications, the penetrator may be retracted into the vessel wall penetrating catheter and the vessel wall penetrating catheter may be removed, leaving the delivery catheter in place for chronic or continuous delivery of substance(s) to and/or obtaining of information or samples from the target site. Alternatively, a delivery catheter having an occlusion member or balloon may be advanced into a vein or venule and the occlusion member or balloon may be used to occlude the lumen of the vein or venule during and after injection of a substance through the catheter, such that the substance will not be carried away by normal venous blood flow and will remain in the vein or venule for a sufficient period of time to have its intended effect (e.g. to enter adjacent tissues through capillary beds drained by that vein or venule).
摘要翻译：用于将物质或装置输送到位于人或动物患者体内的血管外的位置的方法和装置。将血管壁穿透导管插入脉管系统中，定位并定向在目标血管外部位附近的血管内，并且穿透器从导管前进，以便沿目标部位的方向向外穿过血管壁。此后，输送导管穿过穿透器的内腔到目标部位。然后将所需的物质或装置输送到目标部位或从目标部位获得。在一些应用中，穿透器可以缩回到穿过导管的血管壁中，并且可以移除穿透导管的血管壁，使输送导管留在适当位置，以便将物质慢慢地或连续地递送到和/或获得信息或样品从目标网站。或者，具有闭塞构件或气囊的输送导管可以推入静脉或小静脉中，并且阻塞构件或气囊可以在通过导管注射物质期间和之后用于闭塞静脉或小静脉的内腔，使得该物质不会被正常的静脉血流带走，并将在静脉或小静脉中保持足够的时间以达到其预期效果（例如，通过由该静脉或小静脉排出的毛细血管床进入相邻组织）。

38. 发明申请

US20070249985A1 DEVICE AND METHOD FOR ESTABLISHING AN ARTIFICIAL ARTERIO-VENOUS FISTULA 有权
标题翻译：用于建立人造病毒性静脉炎的装置和方法
公开(公告)号：US20070249985A1
公开(公告)日：2007-10-25
申请号：US11696635
申请日：2007-04-04
申请人： Rodney Brenneman , J. Flaherty , Dean Schaefer , Peter Davis , Brad Kellerman
发明人： Rodney Brenneman , J. Flaherty , Dean Schaefer , Peter Davis , Brad Kellerman
IPC分类号： A61M39/18
CPC分类号： A61B17/11 , A61B17/083 , A61B17/10 , A61B17/12009 , A61B2017/00243 , A61B2017/1107 , A61B2017/1139 , C09K8/5083 , C09K8/518 , C09K8/5753 , C09K8/62 , C09K8/68
摘要： A shunt rivet for implantation in the aorta and inferior vena cava to treat chronic obstructive pulmonary disease, and a method of treating chronic obstructive pulmonary disease.
摘要翻译：用于植入主动脉和下腔静脉以治疗慢性阻塞性肺疾病的分流铆钉，以及治疗慢性阻塞性肺疾病的方法。

39. 发明申请

US20070225712A1 Systems and methods for posterior dynamic stabilization of the spine 审中-公开
公开(公告)号：US20070225712A1
公开(公告)日：2007-09-27
申请号：US11801194
申请日：2007-05-09
申请人： Moti Altarac , Stanley Hayes , Joey Reglos , Robert Gutierrez , J. Flaherty
发明人： Moti Altarac , Stanley Hayes , Joey Reglos , Robert Gutierrez , J. Flaherty
IPC分类号： A61B17/58
CPC分类号： A61B17/7052 , A61B17/7004 , A61B17/7005 , A61B17/7019 , A61B17/7032 , A61B17/7037
摘要： A spinal cross-connector for connecting two stabilization rods installed in a patient's spine is provided. The cross-connector includes novel rod attachment elements dynamically connected together by connector elements. The cross-connector provides multi-dimensional adjustability for easy and accurate installation with full lock-down.

40. 发明申请

US20070161991A1 Systems and methods for posterior dynamic stabilization of the spine 有权
公开(公告)号：US20070161991A1
公开(公告)日：2007-07-12
申请号：US11314712
申请日：2005-12-20
申请人： Moti Altarac , Shawn Tebbe , J. Flaherty
发明人： Moti Altarac , Shawn Tebbe , J. Flaherty
IPC分类号： A61F2/30
CPC分类号： A61B17/7065 , A61B17/0206 , A61B17/025 , A61B17/1671 , A61B17/1697 , A61B17/1757 , A61B17/3421 , A61B17/7062 , A61B17/848 , A61B17/8866 , A61B17/8897 , A61B90/39 , A61B2017/00004 , A61B2017/0023 , A61B2017/00261 , A61B2017/00557 , A61B2017/0256 , A61B2017/681 , A61B2090/033 , A61B2090/034 , A61B2090/062 , A61F2/0077
摘要： Devices, systems and methods for dynamically stabilizing the spine are provided. The devices include an expandable spacer having an undeployed configuration and a deployed configuration, wherein the spacer has axial and radial dimensions for positioning between the spinous processes of adjacent vertebrae. The systems include one or more spacers and a mechanical actuation means for delivering and deploying the spacer. The methods involve the implantation of one or more spacers within the interspinous space.

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