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    • 34. 发明申请
    • Transdermal Systems for the Delivery of Ionic Agents Directly to Open Wounds and Surgically Repaired Incisions
    • 透皮系统用于直接输送离子代谢物以开放伤口和手术修复切口
    • US20110112465A1
    • 2011-05-12
    • US13009999
    • 2011-01-20
    • Carter R. AndersonRussell L. MorrisRobert Cohen
    • Carter R. AndersonRussell L. MorrisRobert Cohen
    • A61N1/30
    • A61N1/0448
    • A transdermal system for the delivery of an anesthetic or other active therapeutic agent directly to a selected site of injured skin tissue by iontophoresis is disclosed, which utilizes a transdermal skin-worn patch including a donor electrode chamber containing a donor electrode and an amount of an active agent in a form suitable for transdermal delivery in electrical communication with the donor electrode and a return electrode. The patch also contains a source of electric current connected in a circuit with the donor and return electrode, a current regulating device is optionally provided in the circuit for controlling the electrical output of the patch and at least the donor electrode chamber includes a provision for absorbing a quantity of fluid associated with weepage from adjacent injured skin tissue.
    • 公开了一种用于通过离子电渗法将麻醉剂或其它活性治疗剂直接递送至受损皮肤组织的选定部位的透皮系统,其利用透皮的皮肤佩戴的贴片,其包括供体电极室,其包含施主电极和 活性剂,其形式适合于与供体电极和返回电极电连通的透皮递送。 贴片还包含与供体和返回电极在电路中连接的电流源,电路中可选地提供电流调节装置,用于控制贴片的电输出,并且至少供体电极室包括用于吸收 与来自相邻受伤皮肤组织的渗漏相关的一定量的流体。
    • 36. 发明授权
    • Transdermal systems for the delivery of ionic agents directly to open wounds and surgically repaired incisions
    • 用于将离子剂直接递送至开放性伤口和手术修复的切口的透皮系统
    • US07904146B2
    • 2011-03-08
    • US11937769
    • 2007-11-09
    • Carter R. AndersonRussell L. MorrisRobert Cohen
    • Carter R. AndersonRussell L. MorrisRobert Cohen
    • A61N1/30A61M31/00A61F13/00
    • A61N1/0448
    • A transdermal system for the delivery of an anesthetic or other active therapeutic agent directly to a selected site of injured skin tissue by iontophoresis is disclosed, which utilizes a transdermal skin-worn patch including a donor electrode chamber containing a donor electrode and an amount of an active agent in a form suitable for transdermal delivery in electrical communication with the donor electrode and a return electrode. The patch also contains a source of electric current connected in a circuit with the donor and return electrode, a current regulating device is optionally provided in the circuit for controlling the electrical output of the patch and at least the donor electrode chamber includes a provision for absorbing a quantity of fluid associated with weepage from adjacent injured skin tissue.
    • 公开了一种用于通过离子电渗法将麻醉剂或其它活性治疗剂直接递送至受损皮肤组织的选定部位的透皮系统,其利用透皮的皮肤佩戴的贴片,其包括供体电极室,其包含施主电极和 活性剂,其形式适合于与供体电极和返回电极电连通的透皮递送。 贴片还包含与供体和返回电极在电路中连接的电流源,电路中可选地提供电流调节装置,用于控制贴片的电输出,并且至少供体电极室包括用于吸收 与来自相邻受伤皮肤组织的渗漏相关的一定量的流体。
    • 37. 发明申请
    • Transdermal Systems for the Delivery of Ionic Agents Directly to Open Wounds and Surgically Repaired Incisions
    • 透皮系统用于直接输送离子代谢物以开放伤口和手术修复切口
    • US20080114284A1
    • 2008-05-15
    • US11937769
    • 2007-11-09
    • Carter R. AndersonRussell L. MorrisRobert Cohen
    • Carter R. AndersonRussell L. MorrisRobert Cohen
    • A61N1/30
    • A61N1/0448
    • A transdermal system for the delivery of an anesthetic or other active therapeutic agent directly to a selected site of injured skin tissue by iontophoresis is disclosed, which utilizes a transdermal skin-worn patch including a donor electrode chamber containing a donor electrode and an amount of an active agent in a form suitable for transdermal delivery in electrical communication with the donor electrode and a return electrode. The patch also contains a source of electric current connected in a circuit with the donor and return electrode, a current regulating device is optionally provided in the circuit for controlling the electrical output of the patch and at least the donor electrode chamber includes a provision for absorbing a quantity of fluid associated with weepage from adjacent injured skin tissue.
    • 公开了一种用于通过离子电渗法将麻醉剂或其它活性治疗剂直接递送至受损皮肤组织的选定部位的透皮系统,其利用透皮的皮肤佩戴的贴片,其包括供体电极室,其包含施主电极和 活性剂,其形式适合于与供体电极和返回电极电连通的透皮递送。 贴片还包含与供体和返回电极在电路中连接的电流源,电路中可选地提供电流调节装置,用于控制贴片的电输出,并且至少供体电极室包括用于吸收 与来自相邻受伤皮肤组织的渗漏相关的一定量的流体。
    • 38. 发明授权
    • Iontophoretic drug delivery system
    • 离子电渗药物输送系统
    • US06745071B1
    • 2004-06-01
    • US10371851
    • 2003-02-21
    • Carter R. AndersonRussell L. MorrisClayton J. AndersonLori A. Grace
    • Carter R. AndersonRussell L. MorrisClayton J. AndersonLori A. Grace
    • A61N130
    • A61N1/30
    • A reliable, self-contained iontophoretic drug delivery system is disclosed which enjoys a long stable shelf life and which is easy for the user to activate and employ. This system includes a wearable iontophoretic device that is prepackaged as a complete self-contained unit which includes the active species or drug to be administered and counter ions. The system includes a provision for isolating moisture sources from the electrodes and from the power source during storage and provides a simple, user-friendly mechanism to connect the drug to be administered and counter ion reservoirs to the electrodes and the device to the skin of a user in order to activate the device circuit. All elements of the device are contained in a single outer package.
    • 公开了一种可靠,独立的离子电渗药物输送系统,其具有长的稳定的保质期,并且易于使用者活化和使用。 该系统包括可佩戴的离子电渗疗法装置,其预先包装为完整的独立单元,其包括要施用的活性物质或药物和抗衡离子。 该系统包括用于在储存期间从电极和电源隔离水分源的设置,并且提供简单的,用户友好的机制,用于将要施用的药物和反离子储存器连接到电极和装置到皮肤的 用户为了激活设备电路。 设备的所有元素都包含在一个外包装中。