专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明申请

US20070112047A1 SUBSTITUTED 1H-BENZIMIDAZOLE-4-CARBOXAMIDES ARE POTENT PARP INHIBITORS 有权
公开(公告)号：US20070112047A1
公开(公告)日：2007-05-17
申请号：US11560166
申请日：2006-11-15
申请人： Thomas Penning , Sheela Thomas , Gui-Dong Zhu , Jianchun Gong , Vincent Giranda , Viraj Gandhi
发明人： Thomas Penning , Sheela Thomas , Gui-Dong Zhu , Jianchun Gong , Vincent Giranda , Viraj Gandhi
IPC分类号： A61K31/427 , A61K31/4184 , C07D413/04 , C07D235/04
CPC分类号： C07D235/18 , C07D409/04 , C07D413/04 , C07D417/04
摘要： Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of Formula (I), and methods of inhibiting the PARP enzyme comprising compounds of Formula (I).

32. 发明申请

US20070249597A1 PYRAZOLOQUINOLONES ARE POTENT PARP INHIBITORS 有权
标题翻译：吡唑啉酮是残留的PARP抑制剂
公开(公告)号：US20070249597A1
公开(公告)日：2007-10-25
申请号：US11675570
申请日：2007-02-15
申请人： THOMAS PENNING , Gui-Dong Zhu , Virajkumar Gandhi , Jianchun Gong , Vincent Giranda
发明人： THOMAS PENNING , Gui-Dong Zhu , Virajkumar Gandhi , Jianchun Gong , Vincent Giranda
IPC分类号： A61K31/47 , A61K31/497 , A61K31/53 , A61K31/535 , A61P29/00
CPC分类号： C07D471/04 , A61K31/47 , A61K31/497 , A61K31/53 , A61K31/535 , C07D491/04 , C07D495/04
摘要： Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of Formula (I), and methods of inhibiting the PARP enzyme comprising compounds of Formula (I).
摘要翻译：式（I）的化合物抑制PARP酶，并且可用于治疗与PARP相关的疾病或病症。还公开了包含式（I）化合物，包含式（I）化合物的治疗方法的药物组合物，以及抑制包含式（I）化合物的PARP酶的方法。

33. 发明授权

US06878700B1 Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds 失效
标题翻译：细胞粘附抑制抗炎和免疫抑制化合物
公开(公告)号：US06878700B1
公开(公告)日：2005-04-12
申请号：US09541795
申请日：2000-03-31
申请人： James Link , Gang Liu , ZhongHua Pei , Tom von Geldern , Martin Winn , Zhili Xin , Steven A. Boyd , Gui-Dong Zhu , Jennifer C. Freeman , Indrani W. Gunawardana , Michael A. Staeger , Hwan-Soo Jae , John K. Lynch , Sheldon Wang
发明人： James Link , Gang Liu , ZhongHua Pei , Tom von Geldern , Martin Winn , Zhili Xin , Steven A. Boyd , Gui-Dong Zhu , Jennifer C. Freeman , Indrani W. Gunawardana , Michael A. Staeger , Hwan-Soo Jae , John K. Lynch , Sheldon Wang
IPC分类号： A61K31/454 , A61K31/495 , A61K31/496 , A61K31/537 , A61K31/54 , C07C323/62 , C07D205/04 , C07D207/09 , C07D207/14 , C07D207/26 , C07D207/27 , C07D209/08 , C07D211/20 , C07D211/46 , C07D211/60 , C07D213/40 , C07D213/81 , C07D217/06 , C07D241/04 , C07D295/185 , C07D295/26 , C07D401/04 , C07D521/00 , A61K31/33 , A61K31/415 , C07D221/02 , C07D265/30 , C07D319/00
CPC分类号： C07D207/27 , A61K31/454 , A61K31/495 , A61K31/496 , A61K31/537 , A61K31/54 , C07C323/62 , C07C2601/02 , C07D205/04 , C07D207/09 , C07D207/14 , C07D209/08 , C07D211/20 , C07D211/46 , C07D211/60 , C07D213/40 , C07D213/81 , C07D217/06 , C07D231/12 , C07D233/56 , C07D241/04 , C07D249/08 , C07D295/185 , C07D295/26 , C07D401/04
摘要： The present invention relates to novel cinnamide compounds that are useful for treating inflammatory and immunune diseases, to pharmaceutical compositions containing these compounds, and to methods of inhibiting inflammation or suppressing immune response in a mammal.
摘要翻译：本发明涉及可用于治疗炎性和免疫疾病的新型肉桂酰胺化合物，含有这些化合物的药物组合物，以及抑制哺乳动物炎症或抑制免疫应答的方法。

34. 发明授权

US06831175B2 Kinase inhibitors 有权
标题翻译：激酶抑制剂
公开(公告)号：US06831175B2
公开(公告)日：2004-12-14
申请号：US10317914
申请日：2002-12-12
申请人： Qun Li , Keith W. Woods , Gui-Dong Zhu , John P. Fischer , Jianchun Gong , Tongmei Li , Virajkumar Gandhi , Sheela A. Thomas , Garrick K. Packard , Xiaohong Song , Jason N. Abrams , Robert B. Diebold , Jürgen Dinges , Charles W. Hutchins , Vincent S. Stoll , Saul H. Rosenberg , Vincent L. Giranda
发明人： Qun Li , Keith W. Woods , Gui-Dong Zhu , John P. Fischer , Jianchun Gong , Tongmei Li , Virajkumar Gandhi , Sheela A. Thomas , Garrick K. Packard , Xiaohong Song , Jason N. Abrams , Robert B. Diebold , Jürgen Dinges , Charles W. Hutchins , Vincent S. Stoll , Saul H. Rosenberg , Vincent L. Giranda
IPC分类号： C07D21136
CPC分类号： C07D401/04 , C07D213/63 , C07D401/12 , C07D401/14 , C07D403/14 , C07D409/14 , C07D471/04 , C07D475/02
摘要： Compounds having the formula are useful for inhibiting protein kinases. Also disclosed are compositions which inhibit protein kinases and methods of inhibiting protein kinases in a patient.
摘要翻译：具有该化学式的化合物可用于抑制蛋白激酶。还公开了抑制蛋白激酶的组合物和抑制患者蛋白激酶的方法。

35. 发明申请

US20060229351A1 2-Substituted-1 H-benzimidazile-4-carboxamides are PARP inhibitors 有权
标题翻译： 2-取代的-1H-苯并咪唑-4-甲酰胺是PARP抑制剂
公开(公告)号：US20060229351A1
公开(公告)日：2006-10-12
申请号：US11401635
申请日：2006-04-11
申请人： Gui-Dong Zhu , Virajkumar Gandhi , Jianchun Gong , Thomas Penning , Vincent Giranda , Sheela Thomas
发明人： Gui-Dong Zhu , Virajkumar Gandhi , Jianchun Gong , Thomas Penning , Vincent Giranda , Sheela Thomas
IPC分类号： A61K31/4184
CPC分类号： C07D235/14 , C07D401/04 , C07D401/12 , C07D403/06
摘要： Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), method of treatment comprising compounds of Formula (I), and methods of inhibiting the PARP enzyme comprising compound of Formula (I).
摘要翻译：式（I）的化合物抑制PARP酶，并且可用于治疗与PARP相关的疾病或病症。还公开了包含式（I）化合物，包括式（I）化合物的治疗方法的药物组合物，以及抑制包含式（I）化合物的PARP酶的方法。

36. 发明授权

US08320564B2 Encrypted signal detection circuit and video device using the same 失效
标题翻译：加密信号检测电路和视频设备使用相同
公开(公告)号：US08320564B2
公开(公告)日：2012-11-27
申请号：US12760531
申请日：2010-04-14
申请人： Gui-Dong Zhu
发明人： Gui-Dong Zhu
IPC分类号： H04N7/167
CPC分类号： H04N7/171 , H04N21/42623 , H04N21/44008 , H04N21/44055
摘要： A video device includes a video signal generation circuit, an encrypted signal detection circuit and a central processing unit (CPU). The encrypted signal detection circuit detects encrypted messages in video signals output from the video signal generation circuit and outputs stable trigger control signals to the CPU, which includes an amplifier circuit, a separation circuit, a reverse circuit, a delay circuit and a trigger circuit. The video signals are amplified via the amplifier circuit and negative phase pulse signals are extracted from the video signals via the separation circuit. The reverse circuit converts the negative phase pulse signals to positive phase pulse signals that are delayed via the delay circuit. The trigger circuit outputs the stable trigger control signals based on the delayed positive phase pulse circuit.
摘要翻译：视频设备包括视频信号产生电路，加密信号检测电路和中央处理单元（CPU）。加密信号检测电路检测从视频信号发生电路输出的视频信号中的加密消息，并向CPU发送稳定的触发控制信号，CPU包括放大器电路，分离电路，反向电路，延迟电路和触发电路。通过放大电路对视频信号进行放大，通过分离电路从视频信号中提取负相脉冲信号。反相电路将负相位脉冲信号转换为通过延迟电路延迟的正相脉冲信号。触发电路基于延迟正相脉冲电路输出稳定的触发控制信号。

37. 发明授权

US08013168B2 2-{(R)-2-methylpyrrolidin-2-yl)-1H-benzimidazole-4-carboxamide crystalline form 2 有权
标题翻译： 2 - （（R）-2-甲基吡咯烷-2-基）-1H-苯并咪唑-4-甲酰胺结晶形式2
公开(公告)号：US08013168B2
公开(公告)日：2011-09-06
申请号：US12248988
申请日：2008-10-10
申请人： Gui-Dong Zhu
发明人： Gui-Dong Zhu
IPC分类号： C07D403/04
CPC分类号： C07D487/04
摘要： 2-((R)-2-Methylpyrrolidin-2-yl)-1H-benzimidazole-4-carboxamide Crystalline Form 2, ways to make it, compositions comprising it and made using it, and methods of treating patients having disease using it are disclosed.
摘要翻译： 2 - （（R）-2-甲基吡咯烷-2-基）-1H-苯并咪唑-4-甲酰胺结晶形式2，制备方法，包含它并由其制备的组合物，以及使用其治疗患有疾病的患者的方法是披露

38. 发明授权

US06579882B2 Cell adhesion-inhibiting antiinflammatory compounds 失效
标题翻译：细胞粘附抑制性抗炎化合物
公开(公告)号：US06579882B2
公开(公告)日：2003-06-17
申请号：US09799729
申请日：2001-03-06
申请人： Andrew O. Stewart , Steven A. Boyd , David L. Arendsen , Pramila Bhatia , Kevin R. Condroski , Jennifer C. Freeman , Indrani W. Gunawardana , Gui-Dong Zhu , Kraig Lartey , Catherine M. McCarty , Nicholas A. Mort , Meena V. Patel , Michael A. Staeger , David M. Stout
发明人： Andrew O. Stewart , Steven A. Boyd , David L. Arendsen , Pramila Bhatia , Kevin R. Condroski , Jennifer C. Freeman , Indrani W. Gunawardana , Gui-Dong Zhu , Kraig Lartey , Catherine M. McCarty , Nicholas A. Mort , Meena V. Patel , Michael A. Staeger , David M. Stout
IPC分类号： A61K31519
CPC分类号： C07D493/04 , C07D495/04 , C07D513/04
摘要： Compounds having Formula I are useful for treating inflammation. Also disclosed are pharmaceutical compositions comprising compounds of Formula I, and methods of inhibiting/treating inflammatory diseases in a mammal.
摘要翻译：具有式Iare的化合物可用于治疗炎症。还公开了包含式I化合物的药物组合物，以及哺乳动物抑制/治疗炎性疾病的方法。

39. 发明授权

US06232320B1 Cell adhesion-inhibiting antiinflammatory compounds 有权
标题翻译：细胞粘附抑制性抗炎化合物
公开(公告)号：US06232320B1
公开(公告)日：2001-05-15
申请号：US09325336
申请日：1999-06-03
申请人： Andrew O. Stewart , Steven A. Boyd , David L. Arendsen , Pramila Bhatia , Kevin R. Condroski , Jennifer C. Freeman , Indrani W. Gunawardana , Gui-Dong Zhu , Kraig Lartey , Catherine M. McCarty , Nicholas A. Mort , Meena V. Patel , Michael A. Staeger , David M. Stout
发明人： Andrew O. Stewart , Steven A. Boyd , David L. Arendsen , Pramila Bhatia , Kevin R. Condroski , Jennifer C. Freeman , Indrani W. Gunawardana , Gui-Dong Zhu , Kraig Lartey , Catherine M. McCarty , Nicholas A. Mort , Meena V. Patel , Michael A. Staeger , David M. Stout
IPC分类号： A61K314365
CPC分类号： C07D493/04 , C07D495/04 , C07D513/04
摘要： Compounds having Formula I are useful for treating inflammation. Also disclosed are pharmaceutical compositions comprising compounds of Formula I, and methods of inhibiting/treating inflammatory diseases in a mammal.
摘要翻译：具有式Iare的化合物可用于治疗炎症。还公开了包含式I化合物的药物组合物，以及哺乳动物抑制/治疗炎性疾病的方法。

40. 发明申请

US20090099246A1 2-{(R)-2-METHYLPYRROLIDIN-2-YL)-1H-BENZIMIDAZOLE-4-CARBOXAMIDE CRYSTALLINE FORM 2 有权
标题翻译： 2 - （（R）-2-甲基吡咯烷-2-基）-1H-苯并咪唑-4-羧酰胺结晶形式2
公开(公告)号：US20090099246A1
公开(公告)日：2009-04-16
申请号：US12248988
申请日：2008-10-10
申请人： Gui-Dong Zhu
发明人： Gui-Dong Zhu
IPC分类号： A61K31/4184 , C07D403/02 , A61P35/00
CPC分类号： C07D487/04
摘要： 2-((R)-2-Methylpyrrolidin-2-yl)- I H-benzimidazole-4-carboxamide Crystalline Form 2, ways to make it, compositions comprising it and made using it, and methods of treating patients having disease using it are disclosed.
摘要翻译： 2 - （（R）-2-甲基吡咯烷-2-基）-1H-苯并咪唑-4-甲酰胺结晶形式2，制备方法，包含它并由其制备的组合物，以及使用其治疗患有疾病的患者的方法被披露。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式