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    • 36. 发明授权
    • Ultrasonic treatment chamber for preparing antimicrobial formulations
    • 用于制备抗菌配方的超声波处理室
    • US08215822B2
    • 2012-07-10
    • US11966447
    • 2007-12-28
    • David William KoenigJohn Glen AhlesThomas David EhlertRobert Allen JanssenPaul Warren RasmussenSteve RoffersScott W. WenzelShiming Zhuang
    • David William KoenigJohn Glen AhlesThomas David EhlertRobert Allen JanssenPaul Warren RasmussenSteve RoffersScott W. WenzelShiming Zhuang
    • B01F11/02
    • B01F11/0258B01F2215/0009B01F2215/045B01F2215/0454
    • An ultrasonic mixing system having a treatment chamber in which antimicrobial agents, particularly, hydrophobic antimicrobial agents, can be mixed with one or more formulations is disclosed. Specifically, the treatment chamber has an elongate housing through which a formulation and antimicrobial agents flow longitudinally from a first inlet port and a second inlet port to an outlet port thereof. An elongate ultrasonic waveguide assembly extends within the housing and is operable at a predetermined ultrasonic frequency to ultrasonically energize the formulation and antimicrobial agents within the housing. An elongate ultrasonic horn of the waveguide assembly is disposed at least in part intermediate the inlet and outlet ports, and has a plurality of discrete agitating members in contact with and extending transversely outward from the horn intermediate the inlet and outlet ports in longitudinally spaced relationship with each other. The horn and agitating members are constructed and arranged for dynamic motion of the agitating members relative to the horn at the predetermined frequency and to operate in an ultrasonic cavitation mode of the agitating members corresponding to the predetermined frequency and the formulation and antimicrobial agents being mixed in the chamber.
    • 公开了一种具有处理室的超声波混合系统,其中抗微生物剂,特别是疏水性抗微生物剂可与一种或多种制剂混合。 具体地说,处理室具有细长的壳体,制剂和抗微生物剂通过其从第一入口和第二入口纵向流到其出口。 细长的超声波波导组件在壳体内延伸并且可以预定的超声频率操作,以超声波地激励壳体内的配方和抗微生物剂。 波导组件的细长超声波喇叭至少部分地设置在入口和出口的中间,并且具有多个离散的搅拌构件,其与入口和出口端口处的喇叭中的接触并横向向外延伸,与纵向间隔开的关系 彼此。 喇叭和搅拌构件被构造和布置成用于以预定频率使搅拌构件相对于喇叭的动态运动,并且在对应于预定频率的搅拌构件的超声空化模式下操作,并将制剂和抗微生物剂混合在 房间。
    • 37. 发明授权
    • Ultrasonic treatment chamber for particle dispersion into formulations
    • 超声波处理室用于颗粒分散成配方
    • US08206024B2
    • 2012-06-26
    • US11966418
    • 2007-12-28
    • Scott W. WenzelJohn Glen AhlesThomas David EhlertRobert Allen JanssenDavid William KoenigPaul Warren RasmussenSteve RoffersShiming Zhuang
    • Scott W. WenzelJohn Glen AhlesThomas David EhlertRobert Allen JanssenDavid William KoenigPaul Warren RasmussenSteve RoffersShiming Zhuang
    • B01F11/02
    • B01F11/0258B01F3/1242B01F5/10B01F2215/045B01F2215/0454
    • An ultrasonic mixing system having a particulate dispensing system to dispense particulates into a treatment chamber and the treatment chamber in which particulates can be mixed with one or more formulations is disclosed. Specifically, the treatment chamber has an elongate housing through which a formulation and particulates flow longitudinally from an inlet port to an outlet port thereof. An elongate ultrasonic waveguide assembly extends within the housing and is operable at a predetermined ultrasonic frequency to ultrasonically energize the formulation and particulates within the housing. An elongate ultrasonic horn of the waveguide assembly is disposed at least in part intermediate the inlet and outlet ports, and has a plurality of discrete agitating members in contact with and extending transversely outward from the horn intermediate the inlet and outlet ports in longitudinally spaced relationship with each other. The horn and agitating members are constructed and arranged for dynamic motion of the agitating members relative to the horn at the predetermined frequency and to operate in an ultrasonic cavitation mode of the agitating members corresponding to the predetermined frequency and the formulation and particulates being mixed in the chamber.
    • 公开了一种超声波混合系统,其具有将颗粒分配到处理室中的颗粒分配系统和其中颗粒可以与一种或多种配方混合的处理室。 具体地说,处理室具有细长的外壳,制剂和微粒从入口端口到其出口纵向流动。 细长的超声波波导组件在壳体内延伸并且可以以预定的超声频率操作以超声波地激励配方和微粒在壳体内。 波导组件的细长超声波喇叭至少部分地设置在入口和出口的中间,并且具有多个离散的搅拌构件,其与入口和出口端口处的喇叭中的接触并横向向外延伸,与纵向间隔开的关系 彼此。 喇叭和搅拌构件被构造和布置成用于搅动构件相对于喇叭以预定频率的动态运动,并且以对应于预定频率的搅拌构件的超声空化模式操作,并且将制剂和微粒混合在 房间。