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    • 31. 发明申请
    • MEANS AND METHODS FOR CONTROLLING COMMENSALES
    • 用于控制通信的手段和方法
    • US20110105442A2
    • 2011-05-05
    • US12867766
    • 2009-02-18
    • Ute DechertJurgen EckMichael Krohn
    • Ute DechertJurgen EckMichael Krohn
    • A61K31/122C07C49/647A61K31/60A61K31/17A61Q19/00A01P1/00A01N35/06
    • A61K8/35A61L27/54A61L29/16A61L31/16A61L2300/404A61Q17/005
    • The present invention relates to a cosmetic composition for the cleaning of the skin, said composition comprising or consisting of one or more compounds of formula (I) wherein represents a single bond or double bond; R1 and R2 are independently selected from H, linear or branched C1 to C4 alkyl, linear or branched C1 to C4 alkenyl, linear or branched C1 to C4 alkinyl, and linear or branched C1 to C4 alkanoyl; R4 is selected from H, linear or branched C1 to C4 alkyl, linear or branched C1 to C4 alkenyl, and linear or branched C1 to C4 alkinyl; and R3 and R5 are independently selected from H, OH and halogen, or R3 and R5 together are O to form an epoxid, wherein represents a single bond in case R3 and R5 together are O. Also provided are means and methods for the prevention or reduction of biofilm formation on an intracorporeal device and/or for the removal of biofilm from an intracorporeal device, wherein said biofilm comprises or consists of bacteria of the genus Propionibacterium. Furthermore provided is an intracorporeal device which is coated and/or loaded with one or more compounds as defined above.
    • 本发明涉及一种用于清洁皮肤的化妆品组合物,所述组合物包含一种或多种式(I)化合物或其组合,其中代表单键或双键; R 1和R 2独立地选自H,直链或支链C 1至C 4烷基,直链或支链C 1至C 4烯基,直链或支链C 1至C 4炔基,和直链或支链C 1至C 4烷酰基; R4选自H,直链或支链C1至C4烷基,直链或支链C1至C4烯基,直链或支链C1至C4炔基; 并且R 3和R 5独立地选自H,OH和卤素,或者R 3和R 5一起为O以形成环氧化物,其中在R 3和R 5一起为O的情况下表示单键。还提供了用于预防或 在体内装置中减少生物膜形成和/或从体内装置去除生物膜,其中所述生物膜包含丙酸杆菌属的细菌或由其构成。 此外,提供了一种体外装置,其被涂覆和/或加载一种或多种如上所定义的化合物。
    • 33. 发明授权
    • Child-resistant packaging for tablets
    • 片剂防儿童包装
    • US06679382B1
    • 2004-01-20
    • US09926582
    • 2002-06-03
    • Peter KancsarLaurenz ZellwegerMichael KrohnClaudia SchmauderSusanne Marti
    • Peter KancsarLaurenz ZellwegerMichael KrohnClaudia SchmauderSusanne Marti
    • B65D8304
    • B65D75/5844B65D75/326B65D75/327B65D75/38B65D2215/04B65D2575/3218B65D2575/3227
    • A child-resistant yet senior-friendly packaging for tablets, capsules or similar pharmaceutical products. The packaging is a blister pack (122) with at least one cup (134) that receives tablets (130) in an external package (120), arranged between a base part (124) and a cover part (128), and that is closed by a cover film (136) that can be pressed through. An intermediate part (126) is covered by a cover part (18). A first adhesive (30) is arranged between the base part (14) or the blister pack (122) and the base part (124). The intermeiae part (126) includes a first opening tongue (142) that is preferably linked with the intermediate part (126) via a first perforated line (144) so that it can be detached, and, within said first opening tongue (142), a second opening tongue (146) that is preferably linked with the first opening tongue (142) via a second perforated line (148) so that it can be detached. The second opening tongue (146) can be detached from the first opening tongue (142) once the first opening tongue (142) is removed from the intermediate part (126) and exposes the cover film (136).
    • 适用于片剂,胶囊或类似药物产品的防儿童耐用包装。 包装是具有至少一个杯(134)的泡罩包装(122),其容纳布置在基部(124)和盖部分(128)之间的外包装(120)中的片(130),即, 由能够被按压的盖膜(136)封闭。 中间部分(126)由盖部分(18)覆盖。 第一粘合剂(30)布置在基部(14)或泡罩包装(122)和基部(124)之间。 中间部分(126)包括第一开口舌(142),其优选地经由第一穿孔线(144)与中间部分(126)连接,使得其可以被分离,并且在所述第一开口舌(142)内, ,第二开口舌(146),其优选地经由第二穿孔线(148)与所述第一开口舌片(142)连接,使得其可以被分离。 一旦第一开口舌片(142)从中间部分(126)移除并暴露覆盖薄膜(136),第二开口舌146可以从第一开口舌142分离。