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    • 31. 发明授权
    • Customized refractive correction
    • 定制屈光矫正
    • US07022117B1
    • 2006-04-04
    • US10110894
    • 2000-10-20
    • Kristian HohlaGerhard YoussefiRoland Toennies
    • Kristian HohlaGerhard YoussefiRoland Toennies
    • A61F9/008
    • A61F9/008A61F9/00804A61F9/00817A61F2009/00846A61F2009/00855A61F2009/00872A61F2009/0088A61F2009/00882
    • An aperture card is provided for insertion into a laser refractive ablation system for use in laser ablating the cornea. The aperture card is designed for single surgical use for surgical precautionary considerations and to achieve the highest quality ablations, in addition to reproducibility. The aperture card is loaded into the laser refractive ablation system in a path between the laser system and the eye. The aperture card is precisely located by positioning means and ablative lasing action is inhibited if the card is not positioned within tolerance. Alternatively, the laser system can determine the position of the aperture card and adjust a computed ablation profile or otherwise adjust the optical system to adapt for any misalignment of the apertures in the aperture card. The card contains a “soft spot” aperture capable of shaping a spatial intensity distribution with a unique profile. The profile has a substantially flat top while the sides of the profile slope until an ablation intensity threshold is reached, at which point the sides become substantially vertical. The card can contain more than one soft spot aperture along with a “hard spot” aperture that creates a square-shaped profile used for testing fluence. Each soft spot aperture is formed by a central aperture and a plurality of holes of different sizes surrounding the central aperture and arranged such that the overall diffractive effect produces a soft spot spatial intensity profile compared to the hard, square-sided profile.
    • 提供孔卡用于插入到用于激光烧蚀角膜的激光折射消融系统中。 孔卡被设计用于单次外科手术用于手术预防性考虑,并且除了重现性之外还实现了最高质量的消融。 孔径卡在激光系统和眼睛之间的路径中被加载到激光折射消融系统中。 光圈卡通过定位装置精确定位,如果卡未位于公差范围内,则禁止​​消融激光作用。 或者,激光系统可以确定光圈卡的位置并调整计算的切割轮廓,或者调整光学系统以适应孔径卡中的孔的任何未对准。 该卡包含一个能够形成具有独特轮廓的空间强度分布的“软点”孔。 轮廓具有基本上平坦的顶部,而轮廓的侧面倾斜直到达到消融强度阈值,此时侧面基本上垂直。 该卡可以包含多个软点孔径以及一个“硬点”孔径,创建用于测试注量的方形轮廓。 每个软点孔由围绕中心孔的中心孔和不同尺寸的多个孔形成,并且布置成使得与硬的正方形轮廓相比,整体衍射效应产生软斑空间强度分布。
    • 32. 发明授权
    • Method of controlling apparatus for modifying the surface of the eye
through large beam laser polishing
    • 控制通过大光束激光抛光修饰眼睛表面的装置的方法
    • US5827264A
    • 1998-10-27
    • US487281
    • 1995-06-07
    • Kristian Hohla
    • Kristian Hohla
    • A61B18/20A61B17/00A61F9/00A61F9/007A61F9/008A61F9/01H01S3/00H01S3/10H01S3/225A61N5/02
    • A61F9/008A61F9/00804A61F9/00806A61F9/00817A61B2017/00061A61F2009/00872A61F2009/00882
    • A apparatus and method for controlling an apparatus for removing tissue from the eye performs various types of corrections using a relatively large beam, but oscillating, or dithering, that being to prevent reinforcing ridges from being formed during the tissue removal process. Further, various types of correction, such as hyperopia and astigmatism correction, are performed using a large beam that is scanned over the area to be ablated using overlapping shots. Further, the epithelium in the area to be treated is removed using an infrared fluorescent dye to dye the epithelium, and then observing the fluorescent patterns from the epithelium area to be removed. Once a certain area is no longer fluorescent after laser shots, smaller shots are then applied, selectively removing the epithelium from the remaining regions. Again, the fluorescence patterns are observed, and the process is repeated until no epithelium remains. At this point, all of the epithelium is removed, and further a map is created of the initial epithelial thickness at each point in the area from which the epithelium was removed.
    • 用于控制从眼睛去除组织的装置的装置和方法使用相对大的光束进行各种类型的校正,但是振荡或抖动,以防止在组织去除过程期间形成增强脊。 此外,使用在使用重叠拍摄的要消融的区域上扫描的大束来执行各种类型的校正,例如远视和散光校正。 此外,使用红外荧光染料除去待处理区域中的上皮以染色上皮,然后观察去除上皮区域的荧光图案。 一旦激光照射后某一区域不再荧光,则施加较小的照片,从其余区域选择性地去除上皮。 再次,观察荧光图案,重复该过程,直到没有上皮残留。 此时,除去所有的上皮细胞,并且进一步在去除上皮的区域的每个点处产生初始上皮厚度的图。
    • 34. 发明申请
    • System and Method for Controlled Reduction of Opacities in an Eye
    • 控制减少眼睛不透明度的系统和方法
    • US20130235341A1
    • 2013-09-12
    • US13415679
    • 2012-03-08
    • Frieder LoeselKristian HohlaGwillem Mosedale
    • Frieder LoeselKristian HohlaGwillem Mosedale
    • A61B3/14A61B3/10
    • A61F9/00825A61F9/00834
    • A methodology is provided for correcting the placement of a laser beam's focal point. Specifically, this correction is done to compensate for displacements of the focal point that may be caused when implant material (e.g. an Intraocular Lens (IOL)) is positioned on the optical path of the laser beam. The methodology of the present invention then determines a deviation of the laser beam's refracted target position (uncompensated) from its intended target position. A calculation of the deviation includes considerations of the laser beam's wavelength and refractive/diffractive characteristics introduced by the implant material. This deviation is then added to the refracted target position to make the refracted target position coincide with the intended target position of the focal point. The laser beam will then focus to its intended target position.
    • 提供了一种校正激光束焦点位置的方法。 具体地,进行这种校正以补偿当植入材料(例如人造眼镜(IOL))位于激光束的光路上时可能引起的焦点位移。 然后,本发明的方法确定激光束的折射目标位置(未补偿)与其预期目标位置的偏差。 偏差的计算包括激光束的波长和由植入材料引入的折射/衍射特性的考虑。 然后将该偏差加到折射目标位置,以使折射的目标位置与焦点的预期目标位置一致。 然后激光束将聚焦到其预期的目标位置。
    • 36. 发明授权
    • Method and apparatus for online contact lens evaluation
    • 在线隐形眼镜评估方法和装置
    • US07771053B2
    • 2010-08-10
    • US10565877
    • 2004-07-22
    • Hans-Joachim PollandStefan SeitzKristian HohlaGerhard YoussefiErnst HegelsBirte JansenChristoph Sappel
    • Hans-Joachim PollandStefan SeitzKristian HohlaGerhard YoussefiErnst HegelsBirte JansenChristoph Sappel
    • A61B3/00G02C7/04A61B3/10
    • G02C7/021G02C7/04G02C7/047
    • A selectively marked contact lens having, in one aspect, marks in an optical zone region on a surface thereof and, in another aspect, different marks outside an optical zone region of the lens, for an in-vivo lens. With the lens in-vivo, the subject's eye is illuminated and the lens is imaged. A fast algorithm is used to determine the mark coordinates in relation to a measured pupil coordinate to determine position and/or orientation of the contact lens. A wavefront aberration measurement can also be obtained simultaneously with the contact lens position measurement, as well as pupil size. A fast algorithm provides for online measurements; i.e., at a repetition rate of 10 Hz or greater, over a selected time interval. Blinking periods are determined and anomalous lens position and/or wavefront information is discarded. A most frequently occurring wavefront and/or contact lens position/orientation is determined over the selected time interval.
    • 一个选择性标记的隐形眼镜,在一个方面,在其表面上的光学区域中标记,并且在另一方面,对于体内透镜,在透镜的光学区域外部具有不同的标记。 使用镜片在体内,受试者的眼睛被照亮并且镜片被成像。 使用快速算法来确定相对于测量的瞳孔坐标的标记坐标以确定隐形眼镜的位置和/或取向。 也可以与隐形眼镜位置测量以及瞳孔尺寸同时获得波前像差测量。 快速算法提供在线测量; 即在10Hz或更大的重复频率下,在选定的时间间隔内。 确定闪烁周期,并丢弃异常透镜位置和/或波前信息。 在所选择的时间间隔内确定最频繁出现的波前和/或隐形眼镜位置/取向。
    • 39. 发明授权
    • Simulating a laser treatment on the eye by pretreating a contact lens
    • 通过预处理隐形眼镜来模拟眼睛上的激光治疗
    • US5941874A
    • 1999-08-24
    • US814435
    • 1997-03-10
    • Kristian Hohla
    • Kristian Hohla
    • A61B17/00A61F9/01A61N5/06
    • A61F9/008A61F9/00812A61B2017/00707A61F2009/00872A61F2009/00882
    • A technique and apparatus are provided for simulating a laser treatment on the eye by pretreating a contact lens. A proposed laser treatment is developed using a patient's eye data. That laser treatment is then performed by an excimer laser system onto a contact lens blank. The lens blank is then placed on the patient's eye and the patient's resulting visual acuity are measured. If within acceptable limits, the treatment is then performed on the patient's eye. Otherwise, the treatment pattern is adjusted and the either original lens profiled with the difference or a new lens profiled with the new treatment pattern. This is repeated until the error falls within acceptable limits. Alternatively, spectacle lenses can be used instead of contact lenses.
    • 提供了一种通过预处理隐形眼镜来模拟眼睛上的激光治疗的技术和装置。 使用患者的眼睛数据开发出提出的激光治疗。 然后,激光治疗由准分子激光系统进行到隐形眼镜毛坯上。 然后将镜片坯料放置在患者的眼睛上,并测量患者的所得视力。 如果在可接受的范围内,则对患者的眼睛进行治疗。 否则,调整处理图案,并将原始镜片与差异进行成型,或者使用新的处理图案来形成新的镜片。 这是重复的,直到错误落在可接受的限度内。 或者,可以使用眼镜镜来代替隐形眼镜。