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31. 发明申请

US20070123539A1 Treatment of Restenosis and Stenosis with Dasatinib 审中-公开
标题翻译：用达沙替尼治疗再狭窄和狭窄
公开(公告)号：US20070123539A1
公开(公告)日：2007-05-31
申请号：US11551116
申请日：2006-10-19
申请人： Jie Wu , Zhengming Chen , Kapil Bhalla
发明人： Jie Wu , Zhengming Chen , Kapil Bhalla
IPC分类号： A61K31/506
CPC分类号： A61K31/506
摘要： A method for treating or inhibiting artery obstructive disease, such as restenosis after angioplasty and stenting procedures and stenosis after coronary artery bypass surgery, in a subject by administering to the subject a therapeutically effective amount of dasatinib or a derivative thereof Also provided are drug-eluting medical devices, including stents, having a therapeutically effective amount of dasatinib.
摘要翻译：用于治疗或抑制动脉阻塞性疾病的方法，例如血管成形术和冠状动脉搭桥术后的再狭窄，以及冠状动脉搭桥手术后的狭窄，通过向受试者施用治疗有效量的达沙替尼或其衍生物。还提供了药物洗脱具有治疗有效量的达沙替尼的医疗装置，包括支架。

32. 发明申请

US20060069664A1 Method and system for processing queries intiated by users of mobile devices 有权
标题翻译：用于处理移动设备用户所提出的查询的方法和系统
公开(公告)号：US20060069664A1
公开(公告)日：2006-03-30
申请号：US10957115
申请日：2004-09-30
申请人： Benjamin Ling , Jie Wu , Jian Deng , Hanping Feng
发明人： Benjamin Ling , Jie Wu , Jian Deng , Hanping Feng
IPC分类号： G06F17/30
CPC分类号： G06F17/30867 , G06F17/30979 , G06F17/30991 , H04L51/066 , H04W4/14 , H04W48/16
摘要： In one embodiment, a method for processing queries initiated by users of mobile devices includes receiving an incoming message containing a query initiated be a user of a mobile device, and extracting the query from the received message. The message further includes obtaining a result of the query and creating an outgoing message with the result of the query for delivery to the mobile device.
摘要翻译：在一个实施例中，用于处理由移动设备的用户发起的查询的方法包括：接收包含作为移动设备的用户的发起的查询的传入消息，以及从所接收的消息中提取查询。该消息还包括获得查询的结果并创建具有用于传送到移动设备的查询结果的传出消息。

33. 发明授权

US06926780B2 Method of surface self-nanocrystallization of metallic materials 有权
标题翻译：金属材料表面自我纳米化方法
公开(公告)号：US06926780B2
公开(公告)日：2005-08-09
申请号：US10202241
申请日：2002-07-23
申请人： Tianying Xiong , Tiefan Li , Jie Wu , Huazi Jin , Minjie Wu , Jinsheng Chen , Ming Li
发明人： Tianying Xiong , Tiefan Li , Jie Wu , Huazi Jin , Minjie Wu , Jinsheng Chen , Ming Li
IPC分类号： C21D7/06 , C23C24/04 , C21D1/74
CPC分类号： C21D7/06 , C21D2201/03 , C23C24/04
摘要： The present invention relates to a method of surface treatment of metallic materials, more particularly, to a method of the surface self-nanocrystallization of metallic materials by the bombarding of supersonic fine particles. The method comprises the step of bombarding the surface of metallic substrate material with fine particles at supersonic speed of 300-1200 m/s carried by a compressed gas, which is ejected from a nozzle. The present method can be used for the surface self-nanocrystallization of metallic parts with a complicated structure or a large area, and the nanometer layer obtained is homogeneous. In addition, it can be operated in a simple way with low energy consumption, low cost, high efficiency of production and high surface nanocrystallization rate of from 1 cm2 to 10 cm2/min.
摘要翻译：金属材料的表面处理方法技术领域本发明涉及一种金属材料的表面处理方法，更具体地说，涉及通过轰击超音速微粒而使金属材料的表面自纳晶化的方法。该方法包括用喷射器喷射的压缩气体携带的300-1200m / s超声速度的细颗粒轰击金属基材表面的步骤。本方法可以用于具有复杂结构或大面积的金属部件的表面自纳米结构，并且所获得的纳米层是均匀的。另外，能够以低能耗，低成本，高效率的生产和1cm 2〜10cm 2以上的高表面纳米化速度的简单方式进行操作 > / min。

34. 发明公开

US20230181519A1 Compositions And Methods For Treating Nicotine-Related Disorders And Symptoms Using Dihydromyricetin 审中-公开
公开(公告)号：US20230181519A1
公开(公告)日：2023-06-15
申请号：US17548550
申请日：2021-12-12
申请人： Jie Wu
发明人： Jie Wu
IPC分类号： A61K31/353 , A61P25/34
CPC分类号： A61K31/353 , A61P25/34
摘要： The invention relates to pharmaceutical compositions comprising dihydromyricetin, methods for making such compositions, and methods for using such compositions to treat nicotine-related disorders and habits, such as nicotine addiction, nicotine withdrawal symptoms and the reduction and/or cessation of smoking, vaping, patch, and/or chewing tobacco products.

35. 发明申请

US20200207903A1 AQUEOUS POLYURETHANE DISPERSION ADHESIVE COMPOSITIONS 审中-公开
公开(公告)号：US20200207903A1
公开(公告)日：2020-07-02
申请号：US16612535
申请日：2017-05-11
申请人： Chenyan Bai , Zhaohui Qu , Jie Wu , Kalyan Sehanobish , Hongyu Chen , Xinchun Liu , Chao Zhang
发明人： Chenyan Bai , Zhaohui Qu , Jie Wu , Kalyan Sehanobish , Hongyu Chen , Xinchun Liu , Chao Zhang
IPC分类号： C08G18/10 , C08G18/28 , C08G18/32 , C08G18/73 , C08G18/76 , C08G18/75 , C09J175/06 , C09J175/08 , B32B7/12
摘要： An aqueous polyurethane dispersion compositions are disclosed. The compositions include a polyurethane prepolymer dispersed in an aqueous medium, the polyurethane prepolymer comprising an isocyanate and a crystalline polyester polyol having a hydroxyl content of 20 to 150 mg KOH/g and a melt temperature of less than or equal to 90° C. Methods of forming a laminate are also disclosed. The methods include providing an aqueous polyurethane dispersion, applying the polyurethane dispersion to a surface of the first substrate, bringing the side of the first substrate into contract with a surface of the second substrate, and curing the aqueous dispersion, thereby laminating the first substrate to the second substrate. Laminates formed by the methods and including the compositions are also disclosed.

36. 发明授权

US09174969B2 Indoline scaffold SHP-2 inhibitors and cancer treatment method 有权
标题翻译：吲哚酚支架SHP-2抑制剂和癌症治疗方法
公开(公告)号：US09174969B2
公开(公告)日：2015-11-03
申请号：US13055113
申请日：2009-07-21
申请人： Jie Wu , Nicholas J. Lawrence , Said M. Sebti
发明人： Jie Wu , Nicholas J. Lawrence , Said M. Sebti
IPC分类号： A61K31/496 , C07D209/08 , C07D215/36 , C07D405/06
CPC分类号： C07D405/06 , C07D209/08 , C07D215/36
摘要： The subject invention concerns methods and compounds for inhibiting Shp2. In one embodiment, a compound of the invention has a chemical structure as shown in formula I or II: wherein X, Y, and Z are independently N or S; R1 is cycloalkyl, heterocycloalkyl, aryl, or heteroaryl, any of which can be optionally substituted with one or more of halogen; alkyl; heteroalkyl; —COOH; —C(R3)3, wherein R3 can independently be any of —H or halogen; or —OR4, wherein R4 can be any of H, alkyl, or heteroalkyl; R2 is alkyl, alkylcarbonyl, heteroalkylcarbonyl, aryl, arylcarbonyl, heterocycloalkylcarbonyl, cycloalkylcarbonyl, or —C(O)NR6R7, any of which can be optionally substituted with one or more of halogen; alkyl; heteroalkyl; carbonyl; —OR4, wherein R4 can be —H, alkyl, or heteroalkyl; —OH; —C(R3)3, wherein R3 can independently be any of —H or halogen; aryl, which can be substituted with one or more of halogen or —OR4; heterocycloalkyl; or —C(O)OR5, wherein R5 can be —H or alkyl; R6 and R7 are independently —H, alkyl, heteroalkyl, aryl, or heteroaryl; and R′ is H or alkyl; or a pharmaceutically acceptable salt or hydrate thereof.
摘要翻译：本发明涉及抑制Shp2的方法和化合物。在一个实施方案中，本发明的化合物具有如式I或II所示的化学结构：其中X，Y和Z独立地为N或S; R 1是环烷基，杂环烷基，芳基或杂芳基，其中任何一个可以任选被一个或多个卤素取代; 烷基; 杂烷基; -COOH; -C（R 3）3，其中R 3可以独立地为-H或卤素; 或-OR 4，其中R 4可以是H，烷基或杂烷基中的任何一个; R 2是烷基，烷基羰基，杂烷基羰基，芳基，芳基羰基，杂环烷基羰基，环烷基羰基或-C（O）NR 6 R 7，其中任何一个可以任选被一个或多个卤素取代; 烷基; 杂烷基; 羰; -OR4，其中R4可以是-H，烷基或杂烷基; -哦; -C（R 3）3，其中R 3可以独立地为-H或卤素; 芳基，其可被一个或多个卤素或-OR 4取代; 杂环烷基; 或-C（O）OR 5，其中R 5可以是-H或烷基; R6和R7独立地是-H，烷基，杂烷基，芳基或杂芳基; 和R'是H或烷基; 或其药学上可接受的盐或水合物。

37. 发明申请

US20130231290A1 METHODS OF DIAGNOSING AND TREATING NEURODEGENERATIVE DISEASES 审中-公开
标题翻译：诊断和治疗神经损伤性疾病的方法
公开(公告)号：US20130231290A1
公开(公告)日：2013-09-05
申请号：US13885534
申请日：2011-11-18
申请人： Jie Wu
发明人： Jie Wu
IPC分类号： A61K38/17 , A61K31/13 , G01N33/68 , A61K31/439 , A61K31/47 , C12Q1/68
CPC分类号： A61K38/1703 , A61K31/13 , A61K31/439 , A61K31/47 , A61K31/4748 , A61K38/17 , C12Q1/6883 , C12Q2600/142 , C12Q2600/158 , G01N33/6896
摘要： The present invention relates to methods of diagnosing, treating and prognosing mental disorders, such as Alzheimer's Disease. In one embodiment, the present invention provides a method of treating Alzheimer's Disease by inhibiting dysfunctional signaling of α7 nAChRs in the medial septum region of an individual.
摘要翻译：本发明涉及诊断，治疗和预测精神障碍如阿尔茨海默病的方法。在一个实施方案中，本发明提供了通过抑制个体的内侧隔膜区域中α7nAChRs的功能障碍信号传导来治疗阿尔茨海默氏病的方法。

38. 发明申请

US20130225400A1 METHOD FOR PREPARING HYDROREFINING CATALYST 有权
标题翻译：制备加氢催化剂的方法
公开(公告)号：US20130225400A1
公开(公告)日：2013-08-29
申请号：US13594659
申请日：2012-08-24
申请人： Shunqin Liang , Wei Xie , Zongbao Wang , Huifeng Xue , Guangbi Gong , Tinghai Wang , Jie Wu , Limin Sun , Hongmin Kang , Dehua Huang , Shufeng Wang , Yundi Zheng , Cailan Jiang , Longgang Lv
发明人： Shunqin Liang , Wei Xie , Zongbao Wang , Huifeng Xue , Guangbi Gong , Tinghai Wang , Jie Wu , Limin Sun , Hongmin Kang , Dehua Huang , Shufeng Wang , Yundi Zheng , Cailan Jiang , Longgang Lv
IPC分类号： B01J23/888 , B01J23/887
CPC分类号： B01J23/8885 , B01J23/88 , B01J23/8872 , B01J35/002 , B01J35/1019 , B01J35/1038 , B01J35/1042 , B01J37/0201 , B01J37/0203 , B01J37/08 , C10G45/08 , C10G2300/1037
摘要： A method for preparing hydrorefining catalyst comprises the following steps: (1) mixing an aqueous ammonia solution with a polyamine complexing agent to form a mixed solvent; (2) adding a cobalt salt to the mixed solvent, dissolving the cobalt salt, and then adding a molybdenum salt and optional salts of other active components, and dissolving them to prepare an impregnating solution; and (3) impregnating a support with the impregnating solution, followed by aging, drying, and activating the impregnated support to form a hydrorefining catalyst. The hydrorefining catalyst prepared by this method has good activity, selectivity and stability in use.
摘要翻译：制备加氢精制催化剂的方法包括以下步骤：（1）将氨水溶液与多胺络合剂混合以形成混合溶剂; （2）向混合溶剂中加入钴盐，溶解钴盐，然后加入钼盐和其它活性成分的任意盐，并溶解以制备浸渍溶液; 和（3）用浸渍溶液浸渍载体，然后老化，干燥和活化浸渍的载体以形成加氢精制催化剂。通过该方法制备的加氢精制催化剂在使用中具有良好的活性，选择性和稳定性。

39. 发明申请

US20130208838A1 DETECTION AND FILTERING OF AN UNDESIRED NARROWBAND SIGNAL CONTRIBUTION IN A WIRELESS SIGNAL RECEIVER 有权
标题翻译：无线信号接收机中未受干扰的窄带信号贡献的检测和滤波
公开(公告)号：US20130208838A1
公开(公告)日：2013-08-15
申请号：US13371311
申请日：2012-02-10
申请人： Jie Wu , Emilija M. Simic , Timothy Paul Pals , Duong A. Hoang
发明人： Jie Wu , Emilija M. Simic , Timothy Paul Pals , Duong A. Hoang
IPC分类号： H04B1/10
CPC分类号： G01S19/21 , H04B1/1036
摘要： Techniques are provided which may be implemented using various methods and/or apparatuses in a device comprising a receiver to scan a spectral band of a received signal comprising a desired signal contribution to determine whether signal data associated with at least a sub-band of the spectral band further comprises at least one undesired signal contribution. In response to determining that the signal data comprises at least one undesired signal contribution, the mobile station may initiate at least one notch filter to affect the undesired signal contribution in subsequent signal data associated with the received signal.
摘要翻译：提供了技术，其可以使用包括接收机的各种方法和/或装置来实现，该接收机扫描包括期望信号贡献的接收信号的频谱带，以确定与至少频谱的子带相关联的信号数据频带还包括至少一个不需要的信号贡献。响应于确定信号数据包括至少一个不需要的信号贡献，移动台可以启动至少一个陷波滤波器以影响与接收信号相关联的后续信号数据中的不期望的信号贡献。

40. 发明授权

US08475944B2 Coated ceramic cutting insert and method for making the same 有权
标题翻译：涂层陶瓷切削刀片及其制造方法
公开(公告)号：US08475944B2
公开(公告)日：2013-07-02
申请号：US12722015
申请日：2010-03-11
申请人： Zhigang Ban , Alfred Gates, Jr. , Yixiong Liu , Jie Wu
发明人： Zhigang Ban , Alfred Gates, Jr. , Yixiong Liu , Jie Wu
IPC分类号： B32B9/00
CPC分类号： B23B27/148 , B23B27/141 , B23B2226/18 , B23B2228/10 , B23B2260/144 , C04B41/009 , C04B41/52 , C04B41/89 , C23C28/044 , C23C28/42 , C23C30/005 , Y10T407/27 , C04B35/584 , C04B35/597 , C04B41/4531 , C04B41/5031 , C04B41/459 , C04B41/5061 , C04B41/5068
摘要： A coated ceramic cutting insert for removing material from a workpiece, as well as a method for making the same, that includes a ceramic substrate with a rake surface and at least one flank surface wherein a cutting edge is at the juncture therebetween. A wear-resistant coating scheme that includes an alumina-containing base coating layer region, which has at least one exposed alumina coating layer, deposited by chemical vapor deposition on the substantially all of the surfaces of the ceramic substrate that experience wear during removal of material from the workpiece. The exposed alumina coating layer exhibits a blasted stress condition ranging between about 50 MPa (tensile stress) and about −2 GPa (compressive) as measured by XRD using the Psi tilt method and the (024) reflection of alumina. The exposed alumina coating layer is the result of wet blasting a titanium-containing outer coating layer region from the surface of the alumina-containing base coating layer region.
摘要翻译：一种用于从工件去除材料的涂覆陶瓷切削刀片及其制造方法，其包括具有前刀面和至少一个侧面的陶瓷基体，其中切削刃处于它们之间的接合处。一种耐磨涂层方案，其包括含氧化铝的基底涂层区域，其具有至少一个暴露的氧化铝涂层，其通过化学气相沉积沉积在陶瓷基底的基本上所有的表面上，在去除材料期间经历磨损从工件。暴露的氧化铝涂层表现出通过使用Psi倾斜法和氧化铝的（024）反射通过XRD测量的约50MPa（拉伸应力）和约-2GPa（压缩）之间的喷砂应力条件。暴露的氧化铝涂层是从含氧化铝的基底涂层区域的表面湿式喷射含钛外涂层区域的结果。

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