专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明授权

US5549649A Programmable pacemaker including an atrial rate filter for deriving a filtered atrial rate used for switching pacing modes 失效
标题翻译：可编程起搏器，包括用于导出用于切换起搏模式的滤波心房率的心房速率滤波器
公开(公告)号：US5549649A
公开(公告)日：1996-08-27
申请号：US258014
申请日：1994-06-10
申请人： Joseph J. Florio , Gene A. Bornzin , Paul A. Levine , J. Jeffrey Barlow
发明人： Joseph J. Florio , Gene A. Bornzin , Paul A. Levine , J. Jeffrey Barlow
IPC分类号： A61N1/362 , A61N1/36
CPC分类号： A61N1/3622
摘要： An implantable dual-chamber pacemaker programmed to operate primarily in an atrial tracking mode is provided, where the pacemaker includes an atrial rate smoothing filter for producing a filtered atrial rate from an intrinsic atrial rate, and where the pacemaker automatically switches its mode of operation from the atrial tracking mode to a non-atrial tracking mode in the event the filtered atrial rate exceeds a prescribed upper rate limit. The pacemaker switches from a primary set of operational parameter settings for the primary mode, to an alternate set of operational parameters for the alternate mode when the mode is switched from the primary mode to the alternate mode. The pacemaker also includes the capability of recording and storing mode switching events and data pertaining to the mode switching events.
摘要翻译：提供了一种被编程为主要以心房跟踪模式操作的可植入双室心脏起搏器，其中起搏器包括心房速率平滑滤波器，用于从固有心房率产生经滤波的心房率，并且起搏器自动将其操作模式从在过滤心房率超过规定的上限速率的情况下，将心房跟踪模式转换为非心房跟踪模式。当模式从主模式切换到备用模式时，起搏器从主模式的主要操作参数设置切换到备用模式的备用操作参数集。起搏器还包括记录和存储模式切换事件和与模式切换事件有关的数据的能力。

32. 发明授权

US5514162A System and method for automatically determining the slope of a transfer function for a rate-responsive cardiac pacemaker 失效
标题翻译：用于自动确定速率响应心脏起搏器的传递函数的斜率的系统和方法
公开(公告)号：US5514162A
公开(公告)日：1996-05-07
申请号：US255194
申请日：1994-06-07
申请人： Gene A. Bornzin , Elia R. Arambula , Joseph J. Florio
发明人： Gene A. Bornzin , Elia R. Arambula , Joseph J. Florio
IPC分类号： A61N1/365 , A61N1/36
CPC分类号： A61N1/36542
摘要： A rate-responsive pacemaker measures a patient's level of activity and stores the results in an activity level histogram. The patient's average level of activity is maintained as a running average. Based on a prescribed base pacing rate, a prescribed maximum pacing rate, the average level of activity, and the measured levels of activity stored in the activity level histogram, the rate-responsive pacemaker automatically calculates the slope of the pacemaker transfer function. An activity deviation histogram is also maintained. Analysis of the activity deviation histogram allows the pacemaker to determine if the patient was usually inactive for an extended period of time, and to inhibit an automatic slope calculation under such conditions. If a patient desires to reach a prescribed target heart rate during exercise, the slope may be calculated using the target heart rate and a prescribed fraction of time each week that the patient devotes to exercise.
摘要翻译：速率敏感的起搏器测量患者的活动水平，并将结果存储在活动级直方图中。患者的平均活动水平维持在平均水平。根据规定的基准起搏速率，规定的最大起搏速率，平均活动水平和存储在活动水平直方图中的测量活动水平，速率响应起搏器自动计算起搏器传递函数的斜率。也保持活动偏差直方图。活动偏差直方图的分析允许起搏器确定患者是否通常长时间不活动，并且抑制在这种情况下的自动斜率计算。如果患者希望在运动期间达到规定的目标心率，则可以使用目标心率和患者每周锻炼的规定的时间段来计算斜率。

33. 发明授权

US08818510B2 Systems and methods for paired/coupled pacing 有权
标题翻译：配对/联合起搏的系统和方法
公开(公告)号：US08818510B2
公开(公告)日：2014-08-26
申请号：US12635474
申请日：2009-12-10
申请人： Gene A. Bornzin , Joseph J. Florio
发明人： Gene A. Bornzin , Joseph J. Florio
IPC分类号： A61N1/365
CPC分类号： A61N1/3712 , A61N1/3627 , A61N1/36578
摘要： A coupled/paired stimulus pulse is delivered to the heart at an inter-pulse interval following one of i) detection of an intrinsic depolarization or ii) delivery of a primary stimulus pulse. Capture resulting from the coupled/paired stimulus pulse is sensed for. In response to capture by a coupled/paired stimulus pulse, the inter-pulse interval is incrementally decreased by a first amount until there is no capture by a coupled/paired stimulus pulse. In response to no capture by a coupled/paired stimulus pulse, the inter-pulse interval is incrementally increased by a second amount greater than the first amount, until capture by a coupled/paired stimulus pulse is detected. Once capture is again detected, paired/coupled pacing is delivered at the inter-pulse interval which resulted in capture for a predetermined period of time or until loss of capture occurs.
摘要翻译：耦合/配对的刺激脉冲按照i）检测到内部去极化或ii）主要刺激脉冲的传送之间的脉冲间隔递送到心脏。感测由耦合/配对刺激脉冲产生的捕获。响应于通过耦合/配对的刺激脉冲的捕获，脉冲间隔逐渐减小第一量，直到没有被耦合/配对的刺激脉冲捕获。响应于没有通过耦合/配对刺激脉冲的捕获，脉冲间隔逐渐增加大于第一量的第二量，直到检测到耦合/配对刺激脉冲的捕获。一旦再次检测到捕获，配对/联合起搏将以脉冲间隔传送，这导致捕获预定时间段或直到发生捕获丢失。

34. 发明授权

US08706224B1 Systems and methods for paired/coupled pacing and dynamic overdrive/underdrive pacing 有权
标题翻译：配对/耦合起搏和动态过载/欠驱动起搏的系统和方法
公开(公告)号：US08706224B1
公开(公告)日：2014-04-22
申请号：US11929719
申请日：2007-10-30
申请人： Gene A. Bornzin , Joseph J. Florio , Peter Boileau
发明人： Gene A. Bornzin , Joseph J. Florio , Peter Boileau
IPC分类号： A61N1/365
CPC分类号： A61N1/3628 , A61N1/3621 , A61N1/365 , A61N1/371
摘要： Techniques are described for use with an implantable cardiac stimulation device for performing paired/coupled pacing either alone or in conjunction with dynamic overdrive/underdrive pacing. In one technique, dynamic overdrive/underdrive pacing is delivered to the ventricles using paired pulses during an episode of atrial fibrillation. The use of paired pulses during dynamic ventricular overdrive/underdrive pacing helps lower and stabilize the ventricular rate to thereby reduce the risk of a ventricular arrhythmia. In another technique, the inter-pulse interval between paired pulses is optimized to lengthen the resulting refractory period to improve hemodynamics. Preferably, the optimized inter-pulse interval is used when applying dynamic ventricular overdrive/underdrive pacing with paired pulses so that the benefits of both techniques are obtained. The optimization technique is also applicable to setting the coupling interval for use with coupled pacing.
摘要翻译：描述技术用于可植入心脏刺激装置，用于单独执行配对/联合起搏，或与动态过载/欠驱动起搏结合使用。在一种技术中，在心房颤动发作期间使用配对脉冲将动态超速/欠驱动起搏递送至心室。在动态心室超速/欠驱动起搏期间使用配对脉冲有助于降低和稳定心室率，从而降低室性心律失常的风险。在另一种技术中，配对脉冲之间的脉冲间隔被优化以延长所得的不应期以改善血液动力学。优选地，当应用具有配对脉冲的动态心室超速/欠驱动起搏时使用优化的脉冲间间隔，从而获得两种技术的益处。优化技术也适用于设置耦合起搏使用的耦合间隔。

35. 发明授权

US08504144B2 Systems and methods for employing multiple filters to detect T-wave oversensing and to improve tachyarrhythmia detection within an implantable medical device 有权
标题翻译：使用多个滤波器来检测T波过度感知并改善可植入医疗装置内的快速性心律失常检测的系统和方法
公开(公告)号：US08504144B2
公开(公告)日：2013-08-06
申请号：US11776266
申请日：2007-07-11
申请人： Rupinder Bharmi , Jeffery D. Snell , Gene A. Bornzin , Joseph J. Florio , Peter Boileau
发明人： Rupinder Bharmi , Jeffery D. Snell , Gene A. Bornzin , Joseph J. Florio , Peter Boileau
IPC分类号： A61B5/0452 , A61B5/0456 , A61B5/0464
CPC分类号： A61B5/0464 , A61B5/04014 , A61B5/0456 , A61N1/3622 , A61N1/3925 , A61N1/3962
摘要： Techniques for detecting tachyarrhythmia and also for preventing T-wave oversensing use signals filtered by a narrowband bradycardia filter in combination with signals filtered by a narrowband tachycardia filter. A separate wideband filter may also be used.
摘要翻译：用于检测快速性心律失常并且还用于预防T波超检的技术使用由窄带心动过缓过滤器滤波的信号与由窄带心动过速过滤器过滤的信号组合。也可以使用单独的宽带滤波器。

36. 发明授权

US08180441B2 System and method for distinguishing among cardiac ischemia, hypoglycemia and hyperglycemia using an implantable medical device 有权
标题翻译：使用可植入医疗器械区分心脏缺血，低血糖和高血糖的系统和方法
公开(公告)号：US08180441B2
公开(公告)日：2012-05-15
申请号：US12360822
申请日：2009-01-27
申请人： Jong Gill , Peter Boileau , Rupinder Bharmi , Xiaoyi Min , Joseph J. Florio , Michael E. Benser , Gene A. Bornzin
发明人： Jong Gill , Peter Boileau , Rupinder Bharmi , Xiaoyi Min , Joseph J. Florio , Michael E. Benser , Gene A. Bornzin
IPC分类号： A61B5/0468
CPC分类号： A61N1/3962 , A61B5/0452 , A61B5/0468 , A61B5/14532 , A61N1/3621 , A61N1/3627 , A61N1/36557 , A61N1/3925
摘要： Techniques are described for detecting ischemia, hypoglycemia or hyperglycemia based on intracardiac electrogram (IEGM) signals. Ischemia is detected based on a shortening of the interval between the QRS complex and the end of a T-wave (QTmax), alone or in combination with a change in ST segment elevation. Alternatively, ischemia is detected based on a change in ST segment elevation combined with minimal change in the interval between the QRS complex and the end of the T-wave (QTend). Hypoglycemia is detected based on a change in ST segment elevation along with a lengthening of either QTmax or QTend. Hyperglycemia is detected based on a change in ST segment elevation along with minimal change in QTmax and in QTend. By exploiting QTmax and QTend in combination with ST segment elevation, changes in ST segment elevation caused by hypo/hyperglycemia can be properly distinguished from changes caused by ischemia.
摘要翻译：描述了基于心内电描记图（IEGM）信号检测缺血，低血糖或高血糖的技术。基于QRS复合体与T波结束（QTmax）之间的间隔的缩短单独或与ST段抬高的变化相结合来检测局部缺血。或者，基于ST段抬高的变化结合QRS复合体与T波结束（QTend）之间的间隔的最小变化来检测局部缺血。基于ST段抬高的变化以及QTmax或QTend的延长来检测低血糖。基于ST段抬高的变化以及QTmax和QTend中的最小变化来检测高血糖。通过利用QTmax和QTend与ST段抬高相结合，可以将由低/高血糖引起的ST段抬高的变化与缺血引起的变化进行适当区分。

37. 发明授权

US07792572B1 Ischemia detection using intra-cardiac signals 有权
标题翻译：使用心脏内信号的缺血检测
公开(公告)号：US07792572B1
公开(公告)日：2010-09-07
申请号：US11130858
申请日：2005-05-16
申请人： Jong Gill , Peter Boileau , Gene A. Bornzin , Joseph J. Florio , Mohssen Fard
发明人： Jong Gill , Peter Boileau , Gene A. Bornzin , Joseph J. Florio , Mohssen Fard
IPC分类号： A61B5/0452
CPC分类号： A61B5/0452 , A61B5/7203 , A61B5/7264 , Y10S128/92
摘要： An implanted cardiac rhythm management device is disclosed that is operative to detect myocardial ischemia. This is done by evaluating electrogram features to detect an electrocardiographic change; specifically, changes in electrogram segment during the early part of an ST segment. The early part of the ST segment is chosen to avoid the T-wave.
摘要翻译：公开了可用于检测心肌缺血的植入式心律管理装置。这通过评估电描记图特征来检测心电图变化来完成; 具体来说，在ST段的早期部分的电描绘片段的变化。选择ST段的早期部分以避免T波。

38. 发明申请

US20100081952A1 DETECTING ISCHEMIA USING AN IMPLANTABLE CARDIAC DEVICE BASED ON MORPHOLOGY OF CARDIAC PRESSURE SIGNAL 有权
标题翻译：使用基于心脏压力信号形态的可植入心脏器械检测异常
公开(公告)号：US20100081952A1
公开(公告)日：2010-04-01
申请号：US12632689
申请日：2009-12-07
申请人： Jong Gill , Peter Boileau , Gene A. Bornzin , Joseph J. Florio , Xiaoyi Min
发明人： Jong Gill , Peter Boileau , Gene A. Bornzin , Joseph J. Florio , Xiaoyi Min
IPC分类号： A61B5/0402
CPC分类号： A61B5/0215 , A61B5/0031 , A61B5/042 , A61B5/7239 , A61N1/36564
摘要： Methods and systems are presented for using an ICD to detect myocardial ischemia. One such method includes sensing via an implantable cardiac-rhythm-management device (ICRMD) a signal indicative of cardiac pressure; determining via a processor associated with the ICRMD, a derivative signal that is a first derivative of the sensed signal; measuring via the processor, a maximum positive value of the derivative signal; measuring via the processor, a maximum negative value of the derivative signal; and indicating via the processor, an ischemia based on a comparison of a ratio of the maximum positive value to the maximum negative value with a predetermined value.
摘要翻译：提出了使用ICD检测心肌缺血的方法和系统。一种这样的方法包括通过可植入心律管理装置（ICRMD）感测指示心脏压力的信号; 通过与ICRMD相关联的处理器确定作为感测信号的一阶导数的导数信号; 通过处理器测量导数信号的最大正值; 通过处理器测量导数信号的最大负值; 并且经由处理器指示基于将最大正值与最大负值的比率与预定值进行比较的缺血。

39. 发明授权

US07313444B2 Self-anchoring coronary sinus lead 有权
标题翻译：自固定冠状动脉窦导联
公开(公告)号：US07313444B2
公开(公告)日：2007-12-25
申请号：US10081457
申请日：2002-02-21
申请人： Anne M. Pianca , Kevin L. Morgan , Gene A. Bornzin , Joseph J. Florio , David J. Vachon
发明人： Anne M. Pianca , Kevin L. Morgan , Gene A. Bornzin , Joseph J. Florio , David J. Vachon
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N1/056 , A61N2001/0578 , A61N2001/0585
摘要： An implantable cardiac lead system suitable for placement in the coronary sinus region of the heart. The lead system comprises a lead having two or more non-helical bends in its distal portion. The two or more non-helical bends cooperate to prevent the lead from dislodgment or displacement inside the coronary sinus. The lead system may further comprise a stylet suitable for steering the lead into at least one of the coronary sinus vein, great cardiac vein, left marginal vein, left posterior ventricular vein, and small cardiac vein. The stylet is tapered in its distal portion to provide enhanced maneuverability and steerability inside the coronary sinus region. The lead system may also comprise an introducer which aids in introducing the lead into the heart.
摘要翻译：适用于放置在心脏冠状静脉窦区域的可植入心脏引导系统。引导系统包括在其远端部分中具有两个或多个非螺旋形弯曲部的引线。两个或更多个非螺旋形弯曲合作以防止铅在冠状窦内发生移位或移位。引导系统还可以包括适于将引线引导到冠状静脉窦静脉，大心静脉，左边缘静脉，左后脑室静脉和小心静脉中的至少一个的探针。探针在其远端部分逐渐变细，以在冠状窦区域内提供增强的机动性和可操纵性。引导系统还可以包括有助于将引入引入心脏的导引器。

40. 发明授权

US07043302B1 Methods and apparatus for overdrive pacing heart tissue using an implantable cardiac stimulation device 有权
公开(公告)号：US07043302B1
公开(公告)日：2006-05-09
申请号：US10323380
申请日：2002-12-18
申请人： Joseph J. Florio , Gene A. Bornzin , John W. Poore , Douglas T. Kurschinski
发明人： Joseph J. Florio , Gene A. Bornzin , John W. Poore , Douglas T. Kurschinski
IPC分类号： A61N1/08
CPC分类号： A61N1/368
摘要： Techniques are described for overdrive pacing the heart using a pacemaker wherein the overdrive pacing rate only increases when at least two intrinsic beats are detected within a determined search period. In one specific technique, an increase in the pacing rate occurs only if two P-waves are detected within X cardiac cycles. In another specific technique, the overdrive pacing rate is increased only if at least two P-waves are detected within a block of N cardiac cycles. In both techniques, the overdrive pacing rate is decreased if no increase has occurred in the last Z cardiac cycles. By increasing the overdrive pacing rate only in response to detection of at least two P-waves within a determined number of cardiac cycles, an excessively high overdrive pacing rate is avoided. Other techniques are described for adaptively adjusting overdrive pacing parameters so as to achieve a determined target degree of pacing of, for example, 95% paced beats. By adaptively adjusting overdrive parameters to maintain a target degree of pacing, the average overdrive pacing rate is minimized while still maintaining a high number of paced beats, thereby reducing the risk of a tachyarrhythmia occurring within the patient.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式