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31. 发明授权

US07019524B2 Method, system and computer product for k-space correction of gradient non-linearities 有权
公开(公告)号：US07019524B2
公开(公告)日：2006-03-28
申请号：US10147665
申请日：2002-05-17
申请人： David H. Gurr , Jean H. Brittain , John M. Pauly
发明人： David H. Gurr , Jean H. Brittain , John M. Pauly
IPC分类号： G01V3/00
CPC分类号： G01R33/56375 , G01R33/56518
摘要： One aspect of the invention is a method for reconstructing a moving table MR image. The method comprises receiving an input array that includes a plurality of uncorrected k-space data points. The method further comprises clearing a summation array. For uncorrected k-space data points in the input array the following steps are performed. A kernel associated with the k-space data point is obtained. Corrected data is created in response to the k-space data point, the input array and the kernel. Creating the corrected data includes correcting the uncorrected k-space data point for gradient non-linearities, where the correction is performed in k-space, and correcting the uncorrected k-space data point for table movement. The corrected data is added into the summation array. The image is reconstructed in response to the data in the summation array.

32. 发明授权

US06853191B1 Method of removing dynamic nonlinear phase errors from MRI data 有权
标题翻译：从MRI数据中去除动态非线性相位误差的方法
公开(公告)号：US06853191B1
公开(公告)日：2005-02-08
申请号：US10733011
申请日：2003-12-10
申请人： Karla L. Miller , John M. Pauly
发明人： Karla L. Miller , John M. Pauly
IPC分类号： G01R33/565 , G01R33/567 , G01V3/00
CPC分类号： G01R33/56509 , G01R33/5676
摘要： Disclosed is a generalized reconstruction method that corrects for non-linear phase errors based on least-squares estimation. An approximation of the least squares estimate utilizes refocusing reconstruction in which high-resolution data is multiplied by the phase conjugate of a navigator in image-space. The multiplication rephases the unaliased signal in the high-resolution data. The high-resolution data can then be added together coherently. The multiplication can be effected in k-space as a convolution using a gridding reconstruction of the high-resolution data using the low resolution navigator.
摘要翻译：公开了一种基于最小二乘估计校正非线性相位误差的广义重建方法。最小二乘估计的近似采用重聚焦重建，其中高分辨率数据乘以导航器在图像空间中的相位共轭。该乘法再分辨高分辨率数据中的未混淆信号。然后可以将高分辨率数据相加加在一起。乘法可以在k空间中作为使用低分辨率导航器的高分辨率数据的网格化重建的卷积来实现。

33. 发明授权

US5905377A Method and apparatus for correcting gradient system and static magnetic field in magnetic resonance imaging 失效
标题翻译：用于校正磁共振成像中梯度系统和静磁场的方法和装置
公开(公告)号：US5905377A
公开(公告)日：1999-05-18
申请号：US690528
申请日：1996-07-31
申请人： Adam B. Kerr , John M. Pauly
发明人： Adam B. Kerr , John M. Pauly
IPC分类号： G01R33/389 , G01R33/565 , G01V3/00
CPC分类号： G01R33/389 , G01R33/56518 , G01R33/56563
摘要： Time-varying error between a prescribed magnetic field and an actual magnetic field is identified from a self-encoding technique and the measurement of detected responses to various magnetic read-out gradients. The gradients can be a sinusoidal, step function, or other suitable form which enables the actual responses to be obtained from which transfer functions can be defined. In one embodiment, the data can effectively frequency sample the transfer function of the system. A gradient-recalled echo occurs each time the self-encode lobe is refocussed, and the phase of the echo peak is used to estimate the time variation of the main magnetic field, B.sub.0 (t).
摘要翻译：从自编码技术和对各种磁读出梯度的检测到的响应的测量来识别规定磁场和实际磁场之间的时变误差。梯度可以是正弦，阶梯函数或其他合适的形式，其使得能够从可以定义传递函数获得实际响应。在一个实施例中，数据可以有效地对系统的传递函数进行频率采样。每次自编码波瓣重新聚焦时都会发生梯度回波，回波峰值的相位用于估计主磁场B0（t）的时间变化。

34. 发明授权

US5856744A Method and apparatus for B.sub.0 eddy current compensation by B.sub.1 phase modulation 失效
标题翻译：通过B1相位调制进行B0涡流补偿的方法和装置
公开(公告)号：US5856744A
公开(公告)日：1999-01-05
申请号：US772684
申请日：1996-12-23
申请人： Walter F. Block , Adam B. Kerr , John M. Pauly
发明人： Walter F. Block , Adam B. Kerr , John M. Pauly
IPC分类号： G01R33/565 , G01V3/00
CPC分类号： G01R33/56518
摘要： In accordance with the invention, spatially invariant B.sub.0 eddy currents induced by a slice-selection gradient, G.sub.Z in an MRI system, are compensated by phase modulating the RF excitation pulse with a compensating function. In one embodiment, the compensating function is based on a measure of the integral of the B.sub.0 eddy current. In another embodiment, a scaled copy of the excitation gradient can be used as an approximation of the compensating function.
摘要翻译：根据本发明，通过利用补偿功能对RF激励脉冲进行相位调制来补偿由MRI系统中的切片选择梯度GZ引起的空间不变的B0涡流。在一个实施例中，补偿功能基于B0涡流的积分的度量。在另一个实施例中，可以使用激励梯度的缩放副本作为补偿功能的近似。

35. 发明授权

US5025216A Magnetic resonance imaging of short T.sub.2 species 失效
标题翻译：短T2物种的磁共振成像
公开(公告)号：US5025216A
公开(公告)日：1991-06-18
申请号：US386901
申请日：1989-07-28
申请人： John M. Pauly , Dwight G. Nishimura
发明人： John M. Pauly , Dwight G. Nishimura
IPC分类号： G01R33/48 , G01R33/50 , G01R33/561
CPC分类号： G01R33/446 , G01R33/50
摘要： Magnetic resonance signals for imaging species having short spin-spin relaxation times (T.sub.2) are obtained without the need for a refocusing lobe. A series of RF excitation pulses are applied to the species with magnetic resonance signals being detected after each RF excitation pulse is applied. The magnetic resonance signals are then combined to provide the imaging signals. In one embodiment, each RF excitation pulse is half of a conventional slice-selective pulse with each pulse being slewed to zero.
摘要翻译：获得具有短自旋 - 自旋弛豫时间（T2）的成像物质的磁共振信号，而不需要重新聚焦波瓣。在施加每个RF激励脉冲之后，对具有磁共振信号的物种施加一系列RF激励脉冲。然后将磁共振信号组合以提供成像信号。在一个实施例中，每个RF激励脉冲是常规切片选择脉冲的一半，其中每个脉冲被转换为零。

36. 发明申请

US20180286037A1 Quality of Medical Images Using Multi-Contrast and Deep Learning 审中-公开
公开(公告)号：US20180286037A1
公开(公告)日：2018-10-04
申请号：US15475760
申请日：2017-03-31
申请人： Greg Zaharchuk , Enhao Gong , John M. Pauly
发明人： Greg Zaharchuk , Enhao Gong , John M. Pauly
IPC分类号： G06T7/00 , G06T3/60
摘要： A method of improving diagnostic and functional imaging is provided by obtaining at least two input images of a subject, using a medical imager, where each input image includes a different contrast, generating a plurality of copies of the input images using non-local mean (NLM) filtering, using an appropriately programmed computer, where each input image copy of the subject includes different spatial characteristics, obtaining at least one reference image of the subject, using the medical imager, where the reference image includes imaging characteristics that are different form the input images of the subject, training a deep network model, using data augmentation on the appropriately programmed computer, to adaptively tune model parameters to approximate the reference image from an initial set of the input and reference images, with the goal of outputting an improved quality image of other sets of low SNR low resolution images, for analysis by a physician.

37. 发明授权

US08379951B2 Auto calibration parallel imaging reconstruction method from arbitrary k-space sampling 有权
标题翻译：自动校准平行成像重建方法从任意k空间采样
公开(公告)号：US08379951B2
公开(公告)日：2013-02-19
申请号：US12024919
申请日：2008-02-01
申请人： Michael Lustig , John M. Pauly
发明人： Michael Lustig , John M. Pauly
IPC分类号： G06K9/00 , G06K9/40 , G06K9/36
CPC分类号： G01R33/5611 , G01R33/4824
摘要： A method for obtaining an image by parallel acquisition magnetic resonance imaging (MRI) is provided. Precessing nuclear spins are excited in a region of a subject. A plurality of response signals, representing magnetic resonance signals arising from the precessing nuclear spins, are simultaneously obtained from the region respectively with a plurality of RF reception coils, with each response signal representing a reduced data set of a totality of all of said response signals. Calibration data points are additionally obtained for each data set. A filter is synthesized using the calibration data points. The synthesizing filter is applied to the reduced data set to obtain a plurality of coupled simultaneous linear equations with a plurality of unknowns. The plurality of coupled simultaneously linear equations with the plurality of unknowns is solved to obtain a complete data set.
摘要翻译：提供了一种通过并行采集磁共振成像（MRI）获得图像的方法。核自旋过程在一个主题的地区兴奋起来。分别从具有多个RF接收线圈的区域中同时获得表示从进动的核自旋产生的表示磁共振信号的多个响应信号，每个响应信号表示所有所述响应信号的总和的减少的数据集。为每个数据集额外获得校准数据点。使用校准数据点合成滤波器。将合成滤波器应用于缩减数据集，以获得具有多个未知数的多个耦合的联立线性方程组。解决了具有多个未知数的多个耦合的同时线性方程式以获得完整的数据集。

38. 发明授权

US08035381B2 Optimized spectral-spatial pulse 有权
标题翻译：优化的光谱空间脉冲
公开(公告)号：US08035381B2
公开(公告)日：2011-10-11
申请号：US12259990
申请日：2008-10-28
申请人： Michael Lustig , Charles H. Cunningham , Albert P. Chen , Daniel B. Vigneron , John M. Pauly
发明人： Michael Lustig , Charles H. Cunningham , Albert P. Chen , Daniel B. Vigneron , John M. Pauly
IPC分类号： G01V3/00
CPC分类号： G01R33/4828 , G01R33/5607
摘要： A computer implemented method for designing a spectral-spatial pulse for exciting at least one passband and minimally exciting at least one stopband is provided. A uniform shaped spectral envelope is generated. For a plurality of kz≠0, kz dependent weights for a spectral envelope that approximate a kz=0 envelope and provides the at least one passband and the at least one stopband for each of the plurality of kz≠0 is generated.
摘要翻译：提供了一种用于设计用于激励至少一个通带和最少激励至少一个阻带的频谱空间脉冲的计算机实现的方法。产生均匀形状的光谱包络。对于多个kz≠0，生成近似kz = 0包络并且为多个kz≠0中的每一个提供至少一个通带和至少一个阻带的频谱包络的kz相关权重。

39. 发明申请

US20100102812A1 OPTIMIZED SPECTRAL-SPATIAL PULSE 有权
标题翻译：优化的光谱空间脉冲
公开(公告)号：US20100102812A1
公开(公告)日：2010-04-29
申请号：US12259990
申请日：2008-10-28
申请人： Michael Lustig , Charles H. Cunningham , Albert P. Chen , Daniel B. Vigneron , John M. Pauly
发明人： Michael Lustig , Charles H. Cunningham , Albert P. Chen , Daniel B. Vigneron , John M. Pauly
IPC分类号： G01R33/483 , G01R33/54
CPC分类号： G01R33/4828 , G01R33/5607
摘要： A computer implemented method for designing a spectral-spatial pulse for exciting at least one passband and minimally exciting at least one stopband is provided. A uniform shaped spectral envelope is generated. For a plurality of kz≠0, kz dependent weights for a spectral envelope that approximate a kz=0 envelope and provides the at least one passband and the at least one stopband for each of the plurality of kz≠0 is generated.
摘要翻译：提供了一种用于设计用于激励至少一个通带和最少激励至少一个阻带的频谱空间脉冲的计算机实现的方法。产生均匀形状的光谱包络。对于多个kz≠0，生成近似kz = 0包络并且为多个kz≠0中的每一个提供至少一个通带和至少一个阻带的频谱包络的kz相关权重。

40. 发明授权

US07692423B2 Self navigating cartesian trajectory 有权
标题翻译：自行笛卡尔轨迹
公开(公告)号：US07692423B2
公开(公告)日：2010-04-06
申请号：US11868617
申请日：2007-10-08
申请人： Charles H. Cunningham , Michael Lustig , John M. Pauly
发明人： Charles H. Cunningham , Michael Lustig , John M. Pauly
IPC分类号： G01V3/00
CPC分类号： G01R33/5676
摘要： A method for magnetic resonance imaging (MRI) is provided. A magnetic resonance excitation is provided. A magnetic field is read out through k-space using winders, wherein some of the winders overlap for a length of the winders. Readout data from overlapping lengths of winders is used to estimate motion. The readout may use a two dimensional discrete Fourier transform acquisition.
摘要翻译：提供了一种用于磁共振成像（MRI）的方法。提供磁共振激励。使用络纱机通过k-空间读出磁场，其中一些络纱机在一定长度的络纱机上重叠。来自重叠长度的络纱机的读出数据用于估计运动。读出可以使用二维离散付里叶变换采集。

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