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31. 发明授权

US08426568B2 Rhamnose substituents of SL0101 and therapeutic uses thereof 有权
标题翻译： SL0101的鼠李糖取代基及其治疗用途
公开(公告)号：US08426568B2
公开(公告)日：2013-04-23
申请号：US12301656
申请日：2007-05-22
申请人： Jeffrey A. Smith , Sidney M. Hecht , Deborah A. Lannigan-Macara , David J. Maloney
发明人： Jeffrey A. Smith , Sidney M. Hecht , Deborah A. Lannigan-Macara , David J. Maloney
IPC分类号： C07H17/07 , A61K31/7048
CPC分类号： C07H17/07
摘要： The present invention provides compositions and methods useful for preparing and using analogs, derivatives, and modifications of kaempferols that have anti-neoplastic activity. More specifically, the compounds are analogs, derivatives, and modifications of SLO1O1. The invention further provides compounds that are inhibitors of rsk activity. The invention further provides compounds that selectively inhibit excessive rsk activity in cancers. The present invention further provides methods for treating cancer using compounds of the invention.
摘要翻译：本发明提供了可用于制备和使用具有抗肿瘤活性的山奈酚类似物，衍生物和修饰物的组合物和方法。更具体地说，这些化合物是SLO1O1的类似物，衍生物和修饰物。本发明还提供了作为rsk活性抑制剂的化合物。本发明还提供了选择性抑制癌症中过量的rsk活性的化合物。本发明还提供了使用本发明化合物治疗癌症的方法。

32. 发明授权

US08281927B2 Shipping and display tray with article support 有权
标题翻译：装运和展示托盘与文章支持
公开(公告)号：US08281927B2
公开(公告)日：2012-10-09
申请号：US12963155
申请日：2010-12-08
申请人： Jeffrey A. Smith
发明人： Jeffrey A. Smith
IPC分类号： B65D79/00
CPC分类号： B65D5/5021
摘要： The present invention is directed to a shipping and display tray for holding a plurality of articles contained therein in an upright position at a point of sale. The shipping and display tray is made of paperboard and defined by a one-piece shallow tray having a bottom wall, a front wall, a back wall, and opposite side walls foldably joined with one another. A plurality of parallel spaced apart bumpers are foldably joined to the respective opposite side walls and forming two rows, an aisle, and a plurality of channels when positioned on the bottom wall. The plurality of the channels engages with bottom edges of the plurality of articles to hold the article in standing upright position and prevent the articles from falling over when one of the articles is removed from the display tray. The front wall of the tray includes a flap panel foldably joined thereto and has a pair of openings used to engage with the bumpers.
摘要翻译：本发明涉及一种用于在销售点处以直立位置容纳其中容纳的多个物品的运输和显示托盘。运输和展示托盘由纸板制成，并由具有底壁，前壁，后壁和可折叠地彼此连接的相对侧壁的单件浅托盘限定。多个平行的间隔开的缓冲器可折叠地连接到相应的相对侧壁并且当定位在底壁上时形成两排，通道和多个通道。多个通道与多个物品的底部边缘接合以将物品保持在直立位置，并且当物品从展示托盘中取出时防止物品掉落。托盘的前壁包括可折叠地连接到其上的挡板，并且具有用于与保险杠接合的一对开口。

33. 发明申请

US20090278017A1 SADDLE-ADJUSTING MECHANISM OF A FITNESS APPARATUS 失效
标题翻译：适应性装置的调节机制（SADDLE-ADJUSTINGS A FITNESS APPARATUS）
公开(公告)号：US20090278017A1
公开(公告)日：2009-11-12
申请号：US12117736
申请日：2008-05-08
申请人： Jeffrey A. Smith , Leao Wang
发明人： Jeffrey A. Smith , Leao Wang
IPC分类号： F16M13/02
CPC分类号： A63B22/00 , A63B22/0046 , A63B2225/09 , A63B2225/093
摘要： A saddle-adjusting mechanism of a fitness apparatus having: a) a set of upper and lower parallel slide rails pivotally attached to a front and a rear connecting rod; and b) a saddle support with guide rollers and an engaging gear such that the upper and lower parallel slide rails may be adjusted at a certain angle. Meanwhile, a saddle can be moved forward and backward and maintained at a certain angle so that the operators have a comfortable sitting. Moreover, a back pad support is installed in such a way that a fine adjustment of the backing angle of a back pad is achieved by moving it upward and downward.
摘要翻译：一种健身器具的鞍座调节机构，具有：a）一组上下平行滑轨，其可旋转地安装在前连杆和后连杆上; 以及b）具有引导辊和接合齿轮的鞍形支撑件，使得上和下平行滑轨可以以一定角度被调节。同时，鞍座可以向前和向后移动并保持在一定的角度，使操作者舒适的坐姿。此外，背垫支撑件以这样的方式安装，即通过向上和向下移动来实现背垫的后背角的微调。

34. 发明授权

US07381164B2 Rowing device with a lifting device 失效
标题翻译：具有升降装置的划船装置
公开(公告)号：US07381164B2
公开(公告)日：2008-06-03
申请号：US10887422
申请日：2004-07-09
申请人： Jeffrey A. Smith , Leao Wang
发明人： Jeffrey A. Smith , Leao Wang
IPC分类号： A63B69/06
CPC分类号： A63B22/16 , A63B22/0023 , A63B22/0076 , A63B2022/0079 , A63B2225/09 , Y10S482/908
摘要： A rowing machine having a supporting frame with a seat movable thereon. The supporting frame is pivotally attached to an upright support of a base frame. A lifting device is pivotably interposed between the supporting frame and the base frame for adjusting the angle of the supporting frame relative to the base frame.
摘要翻译：一种划船机，其具有可移动到其上的座椅的支撑框架。支撑框架枢转地附接到基架的直立支撑件。提升装置可枢转地插入在支撑框架和基架之间，用于调节支撑框架相对于基架的角度。

35. 发明授权

US06311843B1 Packaging boxes and components with internal resilient elements 失效
标题翻译：包装盒和具有内部弹性元件的组件
公开(公告)号：US06311843B1
公开(公告)日：2001-11-06
申请号：US09410782
申请日：1999-10-01
申请人： Jeffrey A. Smith , Richard N. Beneroff , Eric Kim , Brian M. Carli
发明人： Jeffrey A. Smith , Richard N. Beneroff , Eric Kim , Brian M. Carli
IPC分类号： B65D8102
CPC分类号： B65D81/075 , B65D5/5028 , B65D75/28
摘要： A series of packaging designs are provided, comprising relatively rigid sheets surrounded by a resilient element, such as a sleeve or tube. The relatively rigid sheets may have appropriately configured end panels, side panels, fold lines, divider panels, or other desired features. Products may be secured inside the sleeve, against the relatively rigid sheet, or against the outside of the sleeve.
摘要翻译：提供了一系列包装设计，包括由弹性元件（例如套筒或管）包围的相对刚性的片材。相对刚性的片材可以具有适当构造的端板，侧板，折叠线，分隔板或其它期望的特征。产品可以固定在套筒内，抵靠相对刚性的片材或套筒外部。

36. 发明授权

US6047884A Boxes with angled inner panels 失效
标题翻译：带有内角的内盒
公开(公告)号：US6047884A
公开(公告)日：2000-04-11
申请号：US160217
申请日：1998-09-24
申请人： Jeffrey A. Smith , Richard N. Beneroff , Eric Kim
发明人： Jeffrey A. Smith , Richard N. Beneroff , Eric Kim
IPC分类号： B65D5/02 , B65D5/4805 , B65D5/50 , B65D5/58 , B65D5/66 , B65D5/28
CPC分类号： B65D5/0281 , B65D5/48008 , B65D5/5004 , B65D5/5014 , B65D5/5016 , B65D5/5035 , B65D5/505 , B65D5/58 , B65D5/6605
摘要： A box with a side panels and at least one closing panel has at least one inner panel associated with one of the closing panels, wherein when the closing panel is in its open position, the inner panel is substantially parallel to that closing panel, and when that closing panel is folded to its closed position, the inner panel is moved toward the center of the box to a distanced position. When the inner panel is in the distanced position, at least a portion of the inner panel is at an oblique angle with respect to both the closing panel with which it is associated and the outer side panel to which that closing panel is connected.
摘要翻译：具有侧板和至少一个封闭板的盒具有至少一个与封闭板中的一个相关联的内板，其中当封闭板处于其打开位置时，内板基本上平行于该关闭板，并且当该关闭面板被折叠到其关闭位置，内部面板朝向盒子的中心移动到远离位置。当内板处于远离位置时，内板的至少一部分相对于与其关联的关闭板和与该关闭板连接的外侧板成两个倾斜角。

37. 发明授权

US5871147A Double panel boxes 失效
标题翻译：双面板盒
公开(公告)号：US5871147A
公开(公告)日：1999-02-16
申请号：US896775
申请日：1997-07-18
申请人： Jeffrey A. Smith , Richard N. Beneroff , Eric Kim
发明人： Jeffrey A. Smith , Richard N. Beneroff , Eric Kim
IPC分类号： B65D5/02 , B65D5/20 , B65D5/4805 , B65D5/50 , B65D5/58 , B65D5/66 , B65D5/28
CPC分类号： B65D5/2009 , B65D5/0281 , B65D5/48008 , B65D5/5014 , B65D5/5016 , B65D5/5035 , B65D5/505 , B65D5/58 , B65D5/6605
摘要： A box includes a plurality of outer panels collectively bounding an accommodation space for accommodating at least one item. At least some of the outer panels have integrally formed inner panels and distancing flaps for holding the item accommodated at a distance from the respective outer panel. The inner panels are distanced from their respective outer panels by folding an associated closing panel or distancing flap with respect to the outer panel.
摘要翻译：盒子包括多个外部面板，它们共同地包围住容纳空间以容纳至少一个物品。至少一些外板具有一体形成的内板和间隔板，用于保持容纳在距相应外板一定距离处的物品。通过相对于外板折叠相关的封闭板或间隔板，内板与它们各自的外板隔开。

38. 发明授权

US5728119A Method and inflatable chamber apparatus for separating layers of tissue 失效
标题翻译：用于分离组织层的方法和充气室装置
公开(公告)号：US5728119A
公开(公告)日：1998-03-17
申请号：US542666
申请日：1995-10-13
申请人： Jeffrey A. Smith , Daniel T. Wallace , Edwin J. Hlavka , Charles Gresl , John P. Lunsford , Albert K. Chin
发明人： Jeffrey A. Smith , Daniel T. Wallace , Edwin J. Hlavka , Charles Gresl , John P. Lunsford , Albert K. Chin
IPC分类号： A61B1/12 , A61B17/00 , A61B17/02 , A61B17/22 , A61B17/30 , A61B17/32 , A61B17/34 , A61B19/00 , A61B19/02 , A61M29/00
CPC分类号： A61B17/3462 , A61B1/00082 , A61B1/015 , A61B1/018 , A61B1/3132 , A61B17/0218 , A61B17/0281 , A61B17/22032 , A61B17/3421 , A61B90/50 , A61B17/00234 , A61B17/3417 , A61B2017/00261 , A61B2017/00535 , A61B2017/00557 , A61B2017/22059 , A61B2017/306 , A61B2017/320044 , A61B2017/320048 , A61B2017/3486 , A61B2090/306 , A61B90/361
摘要： An apparatus for tissue dissection and instrument anchoring, including a dissection balloon having a viewing window (preferably a rigid, transparent window) at its distal end, or including an anchoring or dissection balloon having nonuniform elasticity selected to achieve desired inflated shape and pressure characteristics, and methods for using such apparatus. The window, which can be a lens, is transparent and either rigid or non-rigid but sufficiently strong to retain a desired optical shape while being pushed against tissue layers by a rigid instrument deployed within the balloon. In preferred embodiments, the balloon is a long-necked dissection balloon deployed through a cannula. In other embodiments, the invention is a dissection balloon assembly including a long-necked dissection balloon having a viewing window at its distal end, and a housing to which the dissection balloon's mouth is attached. In use, the distal end of a long-necked dissection balloon is inserted between tissue layers and inflated to dissect the tissue layers.
摘要翻译：一种用于组织解剖和仪器锚定的装置，包括在其远端具有观察窗（优选为刚性的透明窗）的解剖气囊，或包括具有选择的不均匀弹性以获得期望的膨胀形状和压力特性的锚定或解剖球囊，以及使用这种装置的方法。可以是透镜的窗口是透明的，刚性的或非刚性的，但是足够坚固以保持期望的光学形状，同时被部署在气囊内的刚性仪器推压在组织层上。在优选实施例中，气囊是通过插管展开的长颈切开囊。在其它实施例中，本发明是一种解剖气囊组件，其包括在其远端具有观察窗口的长颈解剖气囊，以及与解剖气囊的嘴部连接的外壳。在使用中，将长颈解剖气囊的远端插入组织层之间并充气以解剖组织层。

39. 发明申请

US20100285720A1 MARCHING BAND RIFLE WITH ADJUSTABLE WEIGHTING 审中-公开
标题翻译：具有可调称重的MARCHING带带
公开(公告)号：US20100285720A1
公开(公告)日：2010-11-11
申请号：US12648883
申请日：2009-12-29
申请人： Jeffrey A. Smith , Timothy Mangee
发明人： Jeffrey A. Smith , Timothy Mangee
IPC分类号： A63H33/30
CPC分类号： A63H33/30
摘要： A marching band rifle with adjustable weighting comprising a plastic rifle body includes a stock section and a tip section, where the stock section includes a recess, and a plurality of weights, where each of the weights is removeably and replaceably secured within the recess, and a bolt is removeably and replaceably secured within the recess to secure the plurality of weights to the stock section. Advantageously, the plastic rifle may be more resilient to impact forces caused by the rifle being dropped (for example, not being caught after being thrown) and is less weight than a conventional wooden toy rifle. In addition, the adjustable weighting feature of the rifle allows the rifle weighting to be optimized for each individual to facilitate ease of use.
摘要翻译：具有可调重量的行进带式步枪包括塑料步枪主体，其包括存储部分和尖端部分，其中所述备件部分包括凹部，以及多个重物，其中每个所述重物可移除地且可替换地固定在所述凹部内，以及螺栓可移除地且可替换地固定在凹部内，以将多个重物固定到坯料部分。有利的是，塑料步枪可能对由步枪掉落引起的冲击力（例如，在被扔掉之后不被抓住）更有弹性，并且比常规的木制玩具步枪的重量更小。此外，步枪的可调加权特征允许为每个人优化步枪加权以便于使用。

40. 外观设计

USD624573S1 Vacuum packaging device 有权
公开(公告)号：USD624573S1
公开(公告)日：2010-09-28
申请号：US29356197
申请日：2010-02-22
申请人： Andrew L. Hall , Jeffrey A. Smith , Augusto Picozza , Richard Neil Tobin
设计人： Andrew L. Hall , Jeffrey A. Smith , Augusto Picozza , Richard Neil Tobin

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