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31. 发明申请

US20100329422A1 Radiotherapeutic apparatus 有权
公开(公告)号：US20100329422A1
公开(公告)日：2010-12-30
申请号：US12739206
申请日：2007-10-24
申请人： Kevin Brown , Ralph Streamer , Paul Boxall , Duncan Bourne , Christopher James Gibson
发明人： Kevin Brown , Ralph Streamer , Paul Boxall , Duncan Bourne , Christopher James Gibson
IPC分类号： A61N5/10
CPC分类号： A61N5/103 , A61N5/1036 , A61N5/1042
摘要： A radiotherapeutic apparatus comprises a source able to emit a beam of therapeutic radiation along a beam axis, a multi-leaf collimator arranged to collimate the beam to a desired shape, wherein the source is rotateable about a rotation axis that is substantially orthogonal and intersects with the beam axis thereby to describe an arc around that axis, and further comprises a control means able to control the dose/time rate of the source, the rotation speed of the source, and the multi-leaf collimator position. The control means is arranged to receive a treatment plan in which the arc is divided into a plurality of notional arc-segments, and specifying the total dose for the arc-segment and a Start and end MLC position. It then controls the source in accordance with that plan over an first arc-segment such that at least one of the rotation speed and dose rate are constant and the multi-leaf collimator changes shape, and a second arc segment such that at least one of the rotation speed and dose rate are constant at a level different to the constant level adopted during the first arc-segment. It achieves this by calculating the total time required for the arc segment for a plurality of factors including an MLC leaf movement from a prescribed position at the start of the arc-segment to a prescribed position at the end of the arc-segment, at a maximum leaf speed, rotation of the source from the start to the end of the arc-segment at a maximum source rotation speed, delivery of the dose at a maximum dose rate per time, selecting the factor dictating the longest time, and Controlling the apparatus so that the selected factor operates at its respective maximum and the remaining factors are operated at a reduced rate selected to match that longest time, wherein the total time required for the arc segment for at least one factor relating to a moving geometry item is the greater of (a); a time required to complete the segment at a continuous defined upper speed for the geometry item and (b) a time required to accelerate the geometry item until it is travelling at the defined upper speed. Generally, the time required to accelerate the geometry item to the defined upper speed will include a time to accelerate the geometry item to that speed, and a further time to accelerate the geometry item beyond that speed and subsequently decelerate it until travelling at that speed.

32. 发明授权

US07807079B2 Method of forming orifice plate for fluid ejection device 失效
标题翻译：形成流体喷射装置孔板的方法
公开(公告)号：US07807079B2
公开(公告)日：2010-10-05
申请号：US11030036
申请日：2005-01-05
申请人： John Rausch , Kevin Brown , Rio Rivas
发明人： John Rausch , Kevin Brown , Rio Rivas
IPC分类号： B29C41/20 , B29C41/22
CPC分类号： B41J2/1625 , B41J2/162 , B41J2/1626 , B41J2/1631
摘要： A method of forming an orifice plate for a fluid ejection device includes depositing and patterning a mask material on a conductive surface, forming a first layer on the conductive surface, forming a second layer on the first layer, and removing the first layer and the second layer from the conductive surface, wherein the first layer includes a metallic material and the second layer includes a polymer material.
摘要翻译：一种形成用于流体喷射装置的孔板的方法包括在导电表面上沉积和图案化掩模材料，在导电表面上形成第一层，在第一层上形成第二层，并除去第一层和第二层层，其中所述第一层包括金属材料，并且所述第二层包括聚合物材料。

33. 发明授权

US07685103B2 Method, system, and program for predicate processing by iterator functions 失效
标题翻译：迭代器函数进行谓词处理的方法，系统和程序
公开(公告)号：US07685103B2
公开(公告)日：2010-03-23
申请号：US10675265
申请日：2003-09-29
申请人： Kevin Brown , Raghupathi Keshava Murthy
发明人： Kevin Brown , Raghupathi Keshava Murthy
IPC分类号： G06F17/30
CPC分类号： G06F17/30705 , G06F17/30707 , G06F17/30896 , Y10S707/99933
摘要： Disclosed is a technique for processing predicates in an iterator function. When an iterator function included in a statement is invoked, one or more predicates included in the statement are obtained. The one or more predicates are applied to a row of data. If applying the one or more predicates results in a match, the row of data is returned. If applying the one or more predicates does not result in a match, a search is performed for another row of data for which application of the one or more predicates results in a match. Also disclosed is a technique for processing predicates in which a statement including an iterator function and one or more predicates is received. A qualification descriptor that describes the one or more predicates and one or more functions that are to be used to evaluate the one or more predicates is created. Then, the iterator function is invoked one or more times, until receiving a done indicator from the iterator function.
摘要翻译：公开了一种在迭代器函数中处理谓词的技术。当一个语句中包含的迭代器函数被调用时，会获得语句中包含的一个或多个谓词。一个或多个谓词被应用于一行数据。如果应用一个或多个谓词导致匹配，则返回数据行。如果应用一个或多个谓词不会导致匹配，则对另一行数据执行搜索，为一个或多个谓词的应用导致匹配。还公开了一种用于处理谓词的技术，其中包括迭代器函数和一个或多个谓词的语句被接收。创建描述一个或多个谓词和用于评估一个或多个谓词的一个或多个函数的限定描述符。然后，迭代器函数被调用一次或多次，直到从迭代器函数接收完成的指示符。

34. 发明授权

US07606157B2 Apparatus and method for communicating arbitrarily encoded data over a 1-gigabit ethernet 有权
标题翻译：通过1千兆以太网传送任意编码数据的装置和方法
公开(公告)号：US07606157B2
公开(公告)日：2009-10-20
申请号：US10748290
申请日：2003-12-31
申请人： Kevin Brown , Richard G Thousand
发明人： Kevin Brown , Richard G Thousand
IPC分类号： G08C15/00
CPC分类号： H04L12/40097 , H04L12/2856 , H04L12/2874 , H04L12/40117 , H04L12/6418
摘要： Methods and Systems for transmitting data originating according to a first communications standard over a physical layer using a second communications standard are provided. A data stream is received from a physical transmission medium that uses particular first communications standard. Next, a data type identification (DTID) is appended to each byte in the data stream, thereby creating a technology independent data stream having a particular bit rate. This bit rate is then matched to a different bit rate that corresponds to a second communications standard. The technology independent data stream is then transmitted over a physical transmission medium that uses the second communications standard.
摘要翻译：提供了用于使用第二通信标准在物理层上发送根据第一通信标准发起的数据的方法和系统。从使用特定的第一通信标准的物理传输介质接收数据流。接下来，将数据类型识别（DTID）附加到数据流中的每个字节，从而创建具有特定比特率的与技术无关的数据流。然后，该比特率被匹配到对应于第二通信标准的不同比特率。然后通过使用第二通信标准的物理传输介质来传送与技术无关的数据流。

35. 发明申请

US20090245274A1 Apparatus and method for auto-negotiation in a communication system 有权
标题翻译：通信系统中自动协商的装置和方法
公开(公告)号：US20090245274A1
公开(公告)日：2009-10-01
申请号：US12457093
申请日：2009-06-01
申请人： Walter Hurwitz , Richard G. Thousand , Kevin Brown , Gary Huff
发明人： Walter Hurwitz , Richard G. Thousand , Kevin Brown , Gary Huff
IPC分类号： H04L12/413 , H04J3/22
CPC分类号： H04L12/44 , H04L29/06 , H04L69/24
摘要： A communication system includes a first device and a second device that can advertise multiple capabilities using communication links. A first type of auto-negotiation between the first and second devices is performed using a first communication link between the devices. A second communication link between the devices is used to facilitate a second type of auto-negotiation. For example, the first communication link can include pairs A and B of an IEEE Std. 802.3 four twisted pair cable. The second communication link can include pairs C and D of the cable.
摘要翻译：通信系统包括可以使用通信链路来发布多个能力的第一设备和第二设备。使用设备之间的第一通信链路来执行第一和第二设备之间的第一类型的自动协商。设备之间的第二通信链路用于促进第二种类型的自动协商。例如，第一通信链路可以包括IEEE标准的对A和B。 802.3四条双绞线。第二通信链路可以包括电缆的对C和D。

36. 发明申请

US20090240056A1 METHODS FOR MAKING 4-TETRAZOLYL-4-PHENYLPIPERIDINE COMPOUNDS 有权
标题翻译：制备4-四甲基-4-苯基哌啶化合物的方法
公开(公告)号：US20090240056A1
公开(公告)日：2009-09-24
申请号：US12466797
申请日：2009-05-15
申请人： Kevin Brown , Timothy J. Doyle , John W.F. Whitehead
发明人： Kevin Brown , Timothy J. Doyle , John W.F. Whitehead
IPC分类号： C07D401/02 , C07D257/04 , C09K3/00
CPC分类号： C07D211/64 , C07D257/04 , C07D307/22 , C07D401/04
摘要： Methods, composition, and intermediates are disclosed that are useful for making 4-Tetrazolyl-4-phenylpiperidine Compounds according to Formula I, where Ar1 is —C3-C8 cycloalkyl, phenyl, naphthyl, anthryl, phenanthryl or -(5-7-membered) heteroaryl, each being unsubstituted or substituted with one or more R2 groups; Ar2 is phenyl, naphthyl, anthryl, phenanthryl or -(5-7-membered) heteroaryl, each being unsubstituted or substituted with one or more R2 groups; Z1 and Z2 are each independently a —(C1-C4 alkyl) group; R1 is —(CH2)nC(O)N(R3)(R4) where R3 and R4 are each independently H or —(C1-C4 alkyl); R2 is halogen, —C1-C3 alkyl, —O—(C1-C3 alkyl), —NH(C1-C3 alkyl) or —N(C1-C3 alkyl)2; n is an integer ranging from 1 to 4; m is an integer ranging from 0 to 4; and, in certain embodiments, the phenyl moiety attached to the 4-position of the piperidine ring of a compound according to Formula I can be optionally substituted with one or more R2 groups.
摘要翻译：公开了可用于制备根据式I的4-四唑基-4-苯基哌啶化合物的方法，组合物和中间体，其中Ar 1是-C 3 -C 8环烷基，苯基，萘基，蒽基，菲基或 - （5-7-元））杂芳基，各自为未取代的或被一个或多个R 2基团取代; Ar 2是苯基，萘基，蒽基，菲基或 - （5-7-元）杂芳基，各自是未取代的或被一个或多个R 2基团取代; Z 1和Z 2各自独立地为 - （C 1 -C 4烷基）基团; R1是 - （CH2）nC（O）N（R3）（R4）其中R3和R4各自独立地是H或 - （C1-C4烷基）; R2是卤素，-C1-C3烷基，-O-（C1-C3烷基），-NH（C1-C3烷基）或-N（C1-C3烷基）2; n为1〜4的整数; m为0〜4的整数; 并且在某些实施方案中，连接到根据式I的化合物的哌啶环的4-位的苯基部分可以任选地被一个或多个R 2基团取代。

37. 发明授权

US07557219B2 Methods for making 4-tetrazolyl-4-phenylpiperidine compounds 有权
标题翻译：制备4-四唑基-4-苯基哌啶化合物的方法
公开(公告)号：US07557219B2
公开(公告)日：2009-07-07
申请号：US11495221
申请日：2006-07-28
申请人： Kevin Brown , Timothy J. Doyle , John W. F. Whitehead
发明人： Kevin Brown , Timothy J. Doyle , John W. F. Whitehead
IPC分类号： C07D257/04 , A61K31/445
CPC分类号： C07D211/64 , C07D257/04 , C07D307/22 , C07D401/04
摘要： Methods, composition, and intermediates are disclosed that are useful for making 4-Tetrazolyl-4-phenylpiperidine Compounds according to Formula I, where Ar1 is —C3-C8 cycloalkyl, phenyl, naphthyl, anthryl, phenanthryl or -(5-7-membered) heteroaryl, each being unsubstituted or substituted with one or more R2 groups; Ar2 is phenyl, naphthyl, anthryl, phenanthryl or -(5-7-membered) heteroaryl, each being unsubstituted or substituted with one or more R2 groups; Z1 and Z2 are each independently a —(C1-C4 alkyl) group; R1 is —(CH2)nC(O)N(R3)(R4) where R3 and R4 are each independently H or —(C1-C4 alkyl); R2 is halogen, —C1-C3 alkyl, —O—(C1-C3 alkyl), —NH(C1-C3 alkyl) or —N(C1-C3 alkyl)2; n is an integer ranging from 1 to 4; m is an integer ranging from 0 to 4; and, in certain embodiments, the phenyl moiety attached to the 4-position of the piperidine ring of a compound according to Formula I can be optionally substituted with one or more R2 groups.
摘要翻译：公开了可用于制备根据式I的4-四唑基-4-苯基哌啶化合物的方法，组合物和中间体，其中Ar 1是-C 3 -C 8环烷基，苯基，萘基，蒽基，菲基或 - （5-7-元））杂芳基，各自为未取代的或被一个或多个R 2基团取代; Ar 2是苯基，萘基，蒽基，菲基或 - （5-7-元）杂芳基，各自是未取代的或被一个或多个R 2基团取代; Z 1和Z 2各自独立地为 - （C 1 -C 4烷基）基团; R1是 - （CH2）nC（O）N（R3）（R4）其中R3和R4各自独立地是H或 - （C1-C4烷基）; R2是卤素，-C1-C3烷基，-O-（C1-C3烷基），-NH（C1-C3烷基）或-N（C1-C3烷基）2; n为1〜4的整数; m为0〜4的整数; 并且在某些实施方案中，连接到根据式I的化合物的哌啶环的4-位的苯基部分可以任选地被一个或多个R 2基团取代。

38. 发明申请

US20090121155A1 RADIOTHERAPY APPARATUS AND PARTS THEREOF 审中-公开
标题翻译：放射治疗装置及其部件
公开(公告)号：US20090121155A1
公开(公告)日：2009-05-14
申请号：US11937764
申请日：2007-11-09
申请人： Kevin Brown , Paul Boxall , Christopher James Gibson
发明人： Kevin Brown , Paul Boxall , Christopher James Gibson
IPC分类号： A61N5/00
CPC分类号： A61N5/1042 , A61N5/1048
摘要： A geometry item (such as a gantry arm or an MLC leaf) of a radiotherapeutic apparatus needs to be moved in an accurate manner. The effect of inertia introduces a potential inaccuracy. A radiotherapeutic apparatus is therefore disclosed, comprising a geometry item, a radiation source capable of emitting a beam of therapeutic radiation, and a control unit, the geometry item being moveable to adjust the geometry of the beam, the radiation source having a variable dose rate, and the control unit being arranged to cause variations in the speed of movement of the geometry item and to adjust the dose rate of the radiation source for a period of time after a change in the speed of the geometry item.
摘要翻译：需要以准确的方式移动放射治疗装置的几何物体（例如龙门架或MLC叶）。惯性的影响引起了潜在的不准确性。因此，公开了一种放射治疗装置，其包括几何物体，能够发射治疗辐射束的辐射源和控制单元，所述几何物体可移动以调节所述束的几何形状，所述辐射源具有可变剂量率并且所述控制单元被布置成引起所述几何物体的移动速度的变化并且在所述几何物体的速度改变之后的一段时间内调整所述辐射源的剂量率。

39. 发明申请

US20090110150A1 RADIOTHERAPY APPARATUS AND PARTS THEREOF 有权
标题翻译：放射治疗装置及其部件
公开(公告)号：US20090110150A1
公开(公告)日：2009-04-30
申请号：US11925339
申请日：2007-10-26
申请人： Kevin Brown , Paul Boxall
发明人： Kevin Brown , Paul Boxall
IPC分类号： H05G1/54
CPC分类号： A61N5/1049
摘要： The detected positioning error in a geometry item of a radiotherapy apparatus is generally passed to a transfer function for the system, which outputs a signal that dictates the radiation output. If the detected error is within certain limits then the radiation is permitted whereas outside those limits it is not permitted; this corresponds to a transfer function that is a simple two step function. We propose a transfer function having a result that is (a) substantially zero outside a preset error tolerance, (b) has a maximum result at a point within that tolerance, and (c) has a result that is between zero and that maximum over a range of error values that lie between (i) the error value corresponding to the maximum output and (ii) the preset error tolerance. This means that if an error grows towards (but does not exceed) the error tolerance, the output of the radiation source will reduce and allow time for the geometry item to correct its position.
摘要翻译：放射治疗装置的几何物体中检测到的定位误差通常被传递给系统的传递函数，该系统输出指示辐射输出的信号。如果检测到的误差在一定范围内，则允许辐射，而不允许辐射; 这对应于一个简单的两步函数的传递函数。我们提出一种传递函数，其结果是（a）在预设误差公差之外基本上为零，（b）在该容差内的点处具有最大结果，以及（c）具有在零和最大值之间的结果误差值范围在（i）对应于最大输出的误差值和（ii）预设误差容差之间。这意味着如果误差朝向（但不超过）误差容限增长，则辐射源的输出将减少，并允许几何项的时间来校正其位置。

40. 发明申请

US20070113031A1 Memory management system and method for storing and retrieving messages 审中-公开
标题翻译：用于存储和检索消息的内存管理系统和方法
公开(公告)号：US20070113031A1
公开(公告)日：2007-05-17
申请号：US11274154
申请日：2005-11-16
申请人： Kevin Brown , Michael Spicer
发明人： Kevin Brown , Michael Spicer
IPC分类号： G06F12/00
CPC分类号： G06F12/123 , G06F12/023
摘要： Embodiments of the present invention provide an efficient manner to systematically remove data from a memory that has been transferred or copied to disk storage, thereby facilitating faster querying of data residing in the memory. In particular, memory containing data received from data sources is partitioned into a fixed quantity of buckets each associated with a respective time interval. The buckets represent contiguous intervals of time, where each interval is preferably of the same duration. When data arrives, the data is associated with a timestamp and placed in the appropriate bucket associated with a time interval corresponding to that timestamp. If a timestamp falls outside the range of time intervals associated with the buckets, the data corresponding to that timestamp is placed in an additional bucket. Data within the oldest bucket in memory is periodically removed to provide storage capacity for new incoming information.
摘要翻译：本发明的实施例提供了一种有效的方式来系统地从已经传送或复制到磁盘存储器的存储器中移除数据，从而有助于更快地查询驻留在存储器中的数据。特别地，包含从数据源接收的数据的存储器被分割成固定数量的桶，每个桶与相应的时间间隔相关联。桶表示连续的时间间隔，其中每个间隔优选地具有相同的持续时间。当数据到达时，数据与时间戳相关联，并放置在与该时间戳对应的时间间隔相关联的适当桶中。如果时间戳超出与桶相关联的时间间隔范围，则与该时间戳相对应的数据将放置在附加桶中。定期删除内存中最旧的桶中的数据，以提供新的传入信息的存储容量。

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