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31. 发明授权

US07693698B2 Method for identifying or designing a candidate agent that interacts with LINGO-1 polypeptide using a LINGO-1 three-dimensional structure 失效
标题翻译：使用LINGO-1三维结构识别或设计与LINGO-1多肽相互作用的候选试剂的方法
公开(公告)号：US07693698B2
公开(公告)日：2010-04-06
申请号：US11701635
申请日：2007-02-01
申请人： Lidia Mosyak , Brian Dwyer , Mark Johnson , Xiaotian Zhong , Eleonora Presman , James M. Wilhelm , Mark Stahl , William Stuart Somers
发明人： Lidia Mosyak , Brian Dwyer , Mark Johnson , Xiaotian Zhong , Eleonora Presman , James M. Wilhelm , Mark Stahl , William Stuart Somers
IPC分类号： G06G7/58 , G01N31/00
CPC分类号： C07K14/4703 , C07K14/705 , C07K2299/00
摘要： This disclosure relates to LINGO-1 polypeptides, LINGO-1 polypeptide/ligand complexes, crystals of LINGO-1 polypeptides, crystals of LINGO-1 polypeptide/ligand complexes, and related methods and software systems.
摘要翻译：本公开涉及LINGO-1多肽，LINGO-1多肽/配体复合物，LINGO-1多肽的晶体，LINGO-1多肽/配体复合物的晶体，以及相关方法和软件系统。

32. 发明授权

US07641758B2 Method for thermal seaming of polyimides 有权
标题翻译：聚酰亚胺热接缝方法
公开(公告)号：US07641758B2
公开(公告)日：2010-01-05
申请号：US11740267
申请日：2007-04-25
申请人： Gregory Laue , William Clayton , Mark Johnson , Timothy Wright , Kevin Melton , Garrett Poe
发明人： Gregory Laue , William Clayton , Mark Johnson , Timothy Wright , Kevin Melton , Garrett Poe
IPC分类号： G03G15/01
CPC分类号： B29C66/21 , B29C65/006 , B29C65/02 , B29C65/18 , B29C66/0044 , B29C66/1122 , B29C66/232 , B29C66/344 , B29C66/348 , B29C66/43 , B29C66/71 , B29C66/712 , B29C66/73111 , B29C66/73115 , B29C66/73117 , B29C66/80 , B29C66/81422 , B29C66/8341 , B29C66/836 , B29C66/8362 , B29C66/91411 , B29C66/91421 , B29C66/919 , B29C66/91935 , B29C66/91943 , B29K2065/00 , B29K2067/00 , B29K2071/00 , B29K2077/00 , B29K2079/08 , B29K2079/085 , B29K2081/04 , B29L2031/3097 , B64G1/407 , B64G1/44 , B64G1/54 , C08J5/121 , C08J2379/08
摘要： The present invention is a method for seaming a polyimide material. The method involves forming an interface between multiple the polyimide materials. Next, heat is applied to the interface to soften the polyimide material. The temperature of the heat source is below the melting point of the polyimide material. Finally, pressure is applied to the interface to create a seam between the polyimide materials.
摘要翻译：本发明是一种聚酰亚胺材料的接缝方法。该方法包括在多个聚酰亚胺材料之间形成界面。接下来，将热量施加到界面以软化聚酰亚胺材料。热源的温度低于聚酰亚胺材料的熔点。最后，将压力施加到界面以在聚酰亚胺材料之间形成接缝。

33. 发明申请

US20090313528A1 Method and System for Cooperative Communications with Minimal Coordination 有权
标题翻译：最小协调协作通信方法与系统
公开(公告)号：US20090313528A1
公开(公告)日：2009-12-17
申请号：US12245993
申请日：2008-10-06
申请人： Keith M. Chugg , Mark Johnson
发明人： Keith M. Chugg , Mark Johnson
IPC分类号： H03M13/03 , H04B15/00 , H04L27/34 , G06F11/10 , H03M13/15 , H03M13/05 , G06F7/58
CPC分类号： H04B7/026
摘要： A method and system are provided in a wireless communications system comprising a plurality of nodes (users) working cooperatively. The system provides cooperative diversity by allowing nodes to actively share their antennas and other resources to obtain spatial diversity. The nodes receive the same message (information data) from a common source. Each node enhances the reliability of the message with a modern forward error correction (FEC) code, converts the FEC encoded message into an ensemble of symbols, divides the ensemble of symbols into packets, modulates, dithers and transmits the packets to a receiving node. The dithering process is performed by varying the signal amplitude, phase, frequency and/or symbol timing of the modulated packets. A unique dither pattern is assigned to each node. The receiving node captures a composite signal comprising the transmitted packets of all or most of the transmitting nodes in the cooperative communications system. Because the transmitted packets are dithered independently in phase and/or amplitude, spatial diversity is transformed into temporal diversity.
摘要翻译：在包括多个合作工作的节点（用户）的无线通信系统中提供了一种方法和系统。该系统通过允许节点主动共享其天线和其他资源以获得空间分集来提供协作分集。节点从公共源接收相同的消息（信息数据）。每个节点通过现代前向纠错（FEC）码增强消息的可靠性，将FEC编码的消息转换为符号集合，将符号集合分成包，调制，抖动，并将数据包发送到接收节点。通过改变调制分组的信号幅度，相位，频率和/或符号定时来执行抖动处理。为每个节点分配唯一的抖动模式。接收节点捕获包括合作通信系统中所有或大多数发射节点的传输分组的复合信号。由于发送的分组在相位和/或幅度上独立地抖动，空间分集被转换成时间分集。

34. 发明申请

US20090125501A1 RANKER SELECTION FOR STATISTICAL NATURAL LANGUAGE PROCESSING 有权
标题翻译：用于统计自然语言处理的排名选择
公开(公告)号：US20090125501A1
公开(公告)日：2009-05-14
申请号：US11938811
申请日：2007-11-13
申请人： Jianfeng Gao , Galen Andrew , Mark Johnson , Kristina Toutanova
发明人： Jianfeng Gao , Galen Andrew , Mark Johnson , Kristina Toutanova
IPC分类号： G06F7/10
CPC分类号： G06F17/2715
摘要： Systems and methods for selecting a ranker for statistical natural language processing are provided. One disclosed system includes a computer program configured to be executed on a computing device, the computer program comprising a data store including reference performance data for a plurality of candidate rankers, the reference performance data being calculated based on a processing of test data by each of the plurality of candidate rankers. The system may further include a ranker selector configured to receive a statistical natural language processing task and a performance target, and determine a selected ranker from the plurality of candidate rankers based on the statistical natural language processing task, the performance target, and the reference performance data.
摘要翻译：提供了用于选择用于统计自然语言处理的游戏者的系统和方法。一种公开的系统包括被配置为在计算设备上执行的计算机程序，该计算机程序包括数据存储器，该数据存储器包括用于多个候选排名者的参考演出数据，该参考演出数据是基于每个测试数据的处理来计算的多个候选排名。该系统可以进一步包括配置成接收统计自然语言处理任务和性能目标的排队选择器，并且基于统计自然语言处理任务，性能目标和参考性能来确定来自多个候选排名者的选定队员数据。

35. 发明申请

US20080255028A1 Collagen Receptor I-Domain Binding Modulators 审中-公开
标题翻译：胶原受体I结构域结合调节剂
公开(公告)号：US20080255028A1
公开(公告)日：2008-10-16
申请号：US12066955
申请日：2004-09-15
申请人： Jyrki Heino , Mark Johnson , Jarmo Kapyla , Anne Marjamaki , Tommi Nyronen , Marika Ojala , Olli Pentikainen , Liisa Nissinen
发明人： Jyrki Heino , Mark Johnson , Jarmo Kapyla , Anne Marjamaki , Tommi Nyronen , Marika Ojala , Olli Pentikainen , Liisa Nissinen
IPC分类号： A61K38/02 , G06G7/60 , A61P29/00 , A61P7/02 , A61P35/00
CPC分类号： C07C311/21 , C07C311/53 , C07K14/705 , G01N33/6803 , G01N2333/7055 , G16H50/50 , Y02A90/26
摘要： The present invention relates to a refined and detailed molecular model of the α2⊕1 integrin I-domain, especially the MIDAS and to the use of such a model for designing novel integrin modulators, especially α2β1 integrin modulators. The present invention further relates to novel α2β1 I-domain modulators, which are of therapeutic potential. The present invention further relates to specific families of small molecule modulators interacting with collagen receptors, tetracyclic polyketides and sulfonamides. The present invention further relates to the use of such modulators for the manufacture of medicaments for thrombosis, inflammation and/or cancer
摘要翻译：本发明涉及α2⊕1整合素I结构域，特别是MIDAS的精制和详细的分子模型，以及使用这种模型来设计新的整联蛋白调节剂，特别是α2β1整合素调节剂。本发明还涉及具有治疗潜力的新型α2β1I结构域调节剂。本发明还涉及与胶原受体，四环聚酮化合物和磺酰胺相互作用的小分子调节剂的特定家族。本发明还涉及这种调节剂用于制造用于血栓形成，炎症和/或癌症的药物的用途

36. 发明申请

US20080049489A1 Multi-Bit Spin Memory 失效
标题翻译：多位旋转存储器
公开(公告)号：US20080049489A1
公开(公告)日：2008-02-28
申请号：US11929577
申请日：2007-10-30
申请人： Mark Johnson
发明人： Mark Johnson
IPC分类号： G11C11/02
CPC分类号： H01L43/06 , G01R33/06 , G01R33/1284 , G11B5/378 , G11C11/16 , G11C11/18 , G11C11/5607 , H01L27/222 , H01L27/224 , H01L27/228 , H01L29/66984 , H03K19/18
摘要： A multi-state spin based memory cell uses a pair of ferromagnetic layers. A first ferromagnetic layer can be set to any known state k from a set of n different states by adjusting a magnetic orientation of such layer. The relationship of the first ferromagnetic layer and a second magnetic layer can thus correspond to a value of a data item in a non-volatile multi-bit memory cell.
摘要翻译：基于多状态自旋的存储单元使用一对铁磁层。可以通过调整这种层的磁性取向，将第一铁磁层设置为来自一组n个不同状态的任何已知状态k。因此，第一铁磁层和第二磁性层的关系可以对应于非易失性多位存储单元中的数据项的值。

37. 发明申请

US20080006051A1 PORTABLE COOLER 有权
标题翻译：便携式冷冻机
公开(公告)号：US20080006051A1
公开(公告)日：2008-01-10
申请号：US11773333
申请日：2007-07-03
申请人： Mark Johnson
发明人： Mark Johnson
IPC分类号： F25D3/08 , F25D25/00
CPC分类号： F25D31/006 , F25D2331/802 , F25D2400/38
摘要： The portable cooler is a portable refrigeration system for selectively and adjustably cooling a removable container, such as a beer keg, for example. The portable cooler includes a housing that defines an open interior region for removably receiving the keg. A door is pivotally mounted to the housing, providing the user with selective access to the open interior region. A refrigeration device is mounted within the housing, adjacent the container, and may be powered by an external power supply or by rechargeable batteries, also received within the housing. Wheels are pivotally mounted to a lower end of the housing, and a handle is mounted to an upper end of the housing, allowing the user to selectively transport the housing and keg.
摘要翻译：便携式冷却器是用于选择性地和可调节地冷却例如啤酒桶的可移除容器的便携式制冷系统。便携式冷却器包括限定用于可拆卸地接收小桶的开放内部区域的壳体。门被枢转地安装到壳体，为使用者提供对开放内部区域的选择性接近。制冷装置安装在壳体内，与容器相邻，并且可由外部电源或可充电电池供电，也可以在外壳内容纳。轮子枢转地安装到壳体的下端，并且手柄安装到壳体的上端，允许使用者选择性地运送壳体和小桶。

38. 发明授权

US07313593B1 Method and apparatus for providing full duplex and multipoint IP audio streaming 有权
标题翻译：用于提供全双工和多点IP音频流的方法和装置
公开(公告)号：US07313593B1
公开(公告)日：2007-12-25
申请号：US09695193
申请日：2000-10-24
申请人： Brian Pulito , Mark Johnson , Brian Cline , Jeff Durham , Mark Kressin , Andrew Lochbaum
发明人： Brian Pulito , Mark Johnson , Brian Cline , Jeff Durham , Mark Kressin , Andrew Lochbaum
IPC分类号： G06F15/16
CPC分类号： G06Q10/10
摘要： A conference server enables collaborative communications among a variety of client processes of varying configurations all operatively coupled over a computer network to each other and to the server. The server receives audio streams from participating client processes in a conference, selects which audio streams are active, and broadcasts one or more of the active audio streams to the client processes participating in the conference depending on the clients receiving capabilities and the conference parameters. The client processes receiving multiple active audio streams perform mixing locally at the client node. Without having to perform mixing at the server, resources are saved and the number of simultaneous participating client processes to the conference may be increased accordingly. The server is further capable of simultaneously accommodating multipoint clients and non-multipoint H.323 clients, as well as operating in multiway and “push to talk” modes.
摘要翻译：会议服务器实现各种各样的配置的客户端进程之间的协作通信，这些配置都可以通过计算机网络彼此和服务器可操作地耦合。服务器在会议中从参与的客户端进程接收音频流，选择哪些音频流是活动的，并且根据客户端的接收能力和会议参数，向参与会议的客户端进程广播一个或多个活动音频流。接收多个活动音频流的客户端进程在客户端节点处本地进行混合。无需在服务器上执行混合，节省资源，并可以相应地增加同时参与的会议客户端进程的数量。该服务器还能够同时容纳多点客户端和非多点H.323客户端，以及以多路和“一键通”方式运行。

39. 发明申请

US20070274918A1 LINGO-1 structure 失效
标题翻译： LINGO-1结构
公开(公告)号：US20070274918A1
公开(公告)日：2007-11-29
申请号：US11701635
申请日：2007-02-01
申请人： Lidia Mosyak , Brian Dwyer , Mark Johnson , Xiaotian Zhong , Eleonora Presman , James Wilhelm , Mark Stahl , William Somers
发明人： Lidia Mosyak , Brian Dwyer , Mark Johnson , Xiaotian Zhong , Eleonora Presman , James Wilhelm , Mark Stahl , William Somers
IPC分类号： C07K14/705 , A61K31/00 , A61K49/00 , G01N33/53 , G06G7/58 , G06F9/44 , G01N33/00 , C07K1/00
CPC分类号： C07K14/4703 , C07K14/705 , C07K2299/00
摘要： This disclosure relates to LINGO-1 polypeptides, LINGO-1 polypeptide/ligand complexes, crystals of LINGO-1 polypeptides, crystals of LINGO-1 polypeptide/ligand complexes, and related methods and software systems.
摘要翻译：本公开涉及LINGO-1多肽，LINGO-1多肽/配体复合物，LINGO-1多肽的晶体，LINGO-1多肽/配体复合物的晶体，以及相关方法和软件系统。

40. 发明申请

US20070273637A1 Rail-Stabilized Driving Scheme With Image Memory For An Electrophoretic Display 审中-公开
标题翻译：轨迹稳定驱动方案与电泳显示的图像存储器
公开(公告)号：US20070273637A1
公开(公告)日：2007-11-29
申请号：US10599058
申请日：2005-03-22
申请人： Guofu Zhou , Rogier Cortie , Mark Johnson , Leendert Hage
发明人： Guofu Zhou , Rogier Cortie , Mark Johnson , Leendert Hage
IPC分类号： G09G3/34
CPC分类号： G09G3/344 , G09G3/2007 , G09G2310/0245 , G09G2310/061 , G09G2310/068 , G09G2340/16
摘要： An image is updated on a bi-stable display (310) such as an electrophoretic display in a transition from a current image state to a subsequent image state. A voltage waveform (600, 620, 640, 660; 700, 720, 740, 760) is selected based on the current and subsequent image states, and a previous image state. The bi-stable display (310) is driven from the current image state to the subsequent image state using the selected voltage waveform. For a given transition from the current to the next image state, different waveforms are stored for different previous states, e.g., black, dark grey, light grey and white. The different waveforms may have different drive pulse (DR) or reset pulse (RE1, RE2) energies. In a trial and error optimization process, different waveforms with different reset and/or drive pulse energies are tested for different previous image states to see which waveform yields the smallest greyscale error.
摘要翻译：在从当前图像状态到后续图像状态的转变中，在双稳态显示器（310）上更新图像，例如电泳显示器。基于当前和后续图像状态以及先前的图像状态来选择电压波形（600,620,640,660,700,720,740,760）。使用所选择的电压波形，双稳态显示器（310）从当前图像状态驱动到后续图像状态。对于从当前图像状态到下一图像状态的给定转换，存储不同的先前状态的不同波形，例如黑色，深灰色，浅灰色和白色。不同的波形可能具有不同的驱动脉冲（DR）或复位脉冲（RE 1，RE 2）能量。在试错误优化过程中，针对不同的先前图像状态测试具有不同复位和/或驱动脉冲能量的不同波形，以查看哪个波形产生最小的灰度误差。

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