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31. 发明授权

US07539153B1 Method and apparatus for longest prefix matching based on a trie 有权
标题翻译：基于特里的最长前缀匹配的方法和装置
公开(公告)号：US07539153B1
公开(公告)日：2009-05-26
申请号：US12241513
申请日：2008-09-30
申请人： Jun Liang , Shijun Shen , Meng Li , Juan Zhang , Rui Hu , Jun Gong
发明人： Jun Liang , Shijun Shen , Meng Li , Juan Zhang , Rui Hu , Jun Gong
IPC分类号： G01R31/08
CPC分类号： H04L45/00 , H04L45/7457
摘要： The present invention discloses a method and apparatus for longest prefix matching. The method includes (A) reading a current-level trie node (TNODE) in the trie, (B) determining whether an offset field of the TNODE indicates that a matched prefix exists in an upper level node and, if so, adding the offset field of the TNODE to a pointer that points to a leaf array in the upper level node, updating a current best match pointer with the computation result and executing block (C), otherwise, executing block (C), (C) determining whether the TNODE has a child node according to a child bitmap, when it is determined that a branch flag of the TNODE matches a corresponding bit of a search keyword, and (D) when it is determined that the TNODE has no child node, reading the internal bitmap of the TNODE, computing a longest matched prefix in the TNODE according to the internal bitmap and a pointer that points to a leaf array in the TNODE, updating the current best match pointer with the computation result, and computing an address of a leaf node (LNODE) associated with the current best match pointer.
摘要翻译：本发明公开了一种用于最长前缀匹配的方法和装置。该方法包括：（A）读取该特技中的当前级别的特里节点（TNODE），（B）确定TNODE的偏移字段是否表示在上层节点中存在匹配的前缀，如果是，将TNODE的字段指向指向上级节点中的叶阵列的指针，用计算结果和执行块（C）更新当前最佳匹配指针，否则执行块（C），（C）确定是否当确定TNODE的分支标志与搜索关键字的相应位匹配时，TNODE具有根据子位图的子节点，以及（D）当确定TNODE没有子节点时，读取内部 TNODE的位图，根据内部位图计算TNODE中最长的匹配前缀，以及指向TNODE中的叶阵列的指针，使用计算结果更新当前最佳匹配指针，并计算叶节点的地址（LNODE） nt最佳匹配指针。

32. 发明申请

US20050065075A1 Long lasting fusion peptide inhibitors for hiv infection 失效
标题翻译：持久的融合肽抑制剂用于HIV感染
公开(公告)号：US20050065075A1
公开(公告)日：2005-03-24
申请号：US10478811
申请日：2002-05-31
申请人： John Erickson , Dominique Bridon , Martin Robitaille , Grant Krafft , Dong Xie , Elena Afonina , Jun Liang , Sandra DeMeyer
发明人： John Erickson , Dominique Bridon , Martin Robitaille , Grant Krafft , Dong Xie , Elena Afonina , Jun Liang , Sandra DeMeyer
IPC分类号： A61K47/48 , A61K38/00 , A61P31/14 , A61P31/18 , C07K1/113 , C07K14/00 , C07K14/16 , A61K38/16 , C07K14/47
CPC分类号： C07K14/005 , A61K38/00 , C07K2319/00 , C12N2740/16122
摘要： The present invention relates to C34 peptide derivatives that are inhibitors of viral infection and/or exhibit antifusogenic properties. In particular, this invention relates to C34 derivatives having inhibiting activity against human immunodeficiency virus (HIV), respiratory syncytial virus (RSV), human parainfluenza virus (HPV), measles virus (MeV), and simian immunodeficiency virus (SIV) with long duration of action for the treatment of the respective viral infections.
摘要翻译：本发明涉及作为病毒感染抑制剂和/或显示抗融合性质的C34肽衍生物。特别地，本发明涉及具有长期持续时间的针对人免疫缺陷病毒（HIV），呼吸道合胞病毒（RSV），人副流感病毒（HPV），麻疹病毒（MeV）和猿猴免疫缺陷病毒（SIV））具有抑制活性的C34衍生物的治疗各自病毒感染的作用。

33. 发明授权

US08697708B2 Azabenzothiazole compounds, compositions and methods of use 失效
标题翻译：偶氮苯并噻唑化合物，组合物和使用方法
公开(公告)号：US08697708B2
公开(公告)日：2014-04-15
申请号：US13232778
申请日：2011-09-14
申请人： Toby Jonathan Blench , Charles Ellwood , Simon Charles Goodacre , Yingjie Lai , Jun Liang , Calum Macleod , Steven R. Magnuson , Vickie H. Tsui , Karen Williams , Birong Zhang
发明人： Toby Jonathan Blench , Charles Ellwood , Simon Charles Goodacre , Yingjie Lai , Jun Liang , Calum Macleod , Steven R. Magnuson , Vickie H. Tsui , Karen Williams , Birong Zhang
IPC分类号： A01N43/90 , A61K31/519 , C07D471/00 , C07D487/00 , C07D491/00 , C07D495/00
CPC分类号： A61K31/5377 , A61K31/437 , A61K31/501 , A61K31/506 , A61K31/519 , C07D513/04
摘要： Provided are compounds of Formula I, stereoisomers, tautomers, solvates, prodrugs and pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, R4 and R5 are defined herein, a pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, methods of using the compound or composition in therapy, and methods of manufacturing a compound of Formula I.
摘要翻译：提供式I化合物，立体异构体，互变异构体，溶剂合物，前药和药学上可接受的盐，其中A，X，R 1，R 2，R 4和R 5在本文中定义，药物组合物包括式I化合物和药学上可接受的载体，佐剂或载体，在治疗中使用化合物或组合物的方法，以及制备式I化合物的方法。

34. 发明授权

US08609687B2 Triazolopyridine JAK inhibitor compounds and methods 有权
标题翻译：三唑并吡嗪JAK抑制剂化合物及方法
公开(公告)号：US08609687B2
公开(公告)日：2013-12-17
申请号：US13471269
申请日：2012-05-14
申请人： Bing-Yan Zhu , Michael Siu , Steven R. Magnuson , Richard Pastor , He Haiying , Xiao Yisong , Zheng Jifu , Xu Xing , Zhao Junping , Christopher Hurley , Jun Liang , Wendy Liu , Joseph P. Lyssikatos
发明人： Bing-Yan Zhu , Michael Siu , Steven R. Magnuson , Richard Pastor , He Haiying , Xiao Yisong , Zheng Jifu , Xu Xing , Zhao Junping , Christopher Hurley , Jun Liang , Wendy Liu , Joseph P. Lyssikatos
IPC分类号： A61K31/437 , C07D471/02
CPC分类号： C07D471/04 , A61K31/437 , A61K31/496 , A61K31/5377 , C07D487/04
摘要： A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are defined herein, are useful as JAK kinase inhibitors. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of JAK kinase activity in a patient are disclosed.
摘要翻译：其中R 1，R 2，R 3，R 4和R 5在本文中定义的式I化合物，对映异构体，非对映异构体，互变异构体或其药学上可接受的盐可用作JAK激酶抑制剂。公开了包含式I化合物和药学上可接受的载体，佐剂或载体的药物组合物，以及治疗或减轻对患者中JAK激酶活性的抑制作用的疾病或病症的严重程度的方法。

35. 发明申请

US20130216265A1 DRIVING FORCE TRANSMISSION MECHANISM AND PROCESS CARTRIDGE CONTAINING THE SAME 有权
标题翻译：驱动力传动机构和包含该传动机构的过程盒
公开(公告)号：US20130216265A1
公开(公告)日：2013-08-22
申请号：US13823259
申请日：2011-09-27
申请人： Qingfei Peng , Jun Liang
发明人： Qingfei Peng , Jun Liang
IPC分类号： G03G15/00
CPC分类号： F16D1/10 , F16D1/108 , F16D2001/102 , G03G21/186
摘要： A driving force transmission mechanism comprising a photosensitive drum driving member, wherein the photosensitive drum driving member is engaged with an image forming apparatus driving member and receives the driving force from the image forming apparatus driving member; the image forming apparatus driving member comprises a triangular groove having a triangular cross-section and driving force transmission portion disposed in three vertex angles of the triangular groove; the photosensitive drum driving member comprises a non-distorting protrusion which is axially extended from the end face of a drum shaft and engaged with the groove on the image forming apparatus driving member; the protrusion has a position-limiting mechanism and a stressed mechanism; a projecting tooth obliquely disposed on said non-distorting protrusion is taken as the stressed mechanism; and each projecting tooth also has a mating surface which is engaged with the driving force transmission component to transmit the driving force.
摘要翻译：一种驱动力传递机构，包括感光鼓驱动构件，其中感光鼓驱动构件与图像形成装置驱动构件接合并接收来自图像形成装置驱动构件的驱动力; 图像形成装置驱动构件包括具有三角形横截面的三角形槽和设置在三角形槽的三个顶角的驱动力传递部分; 感光鼓驱动构件包括从鼓轴的端面轴向延伸并与图像形成装置驱动构件上的凹槽接合的非变形突起; 突起具有位置限制机构和应力机构; 倾斜地设置在所述非扭曲突起上的突出齿被用作应力机构; 并且每个突出齿还具有与驱动力传递部件接合以传递驱动力的配合表面。

36. 发明申请

US20120225855A1 TRIAZOLOPYRIDINE JAK INHIBITOR COMPOUNDS AND METHODS 有权
公开(公告)号：US20120225855A1
公开(公告)日：2012-09-06
申请号：US13471269
申请日：2012-05-14
申请人： Bing-Yan Zhu , Michael Siu , Steven R. Magnuson , Richard Pastor , He Haiying , Xiao Yisong , Zheng Jifu , Xu Xing , Zhao Junping , Christopher Hurley , Jun Liang , Wendy Liu , Joseph P. Lyssikatos
发明人： Bing-Yan Zhu , Michael Siu , Steven R. Magnuson , Richard Pastor , He Haiying , Xiao Yisong , Zheng Jifu , Xu Xing , Zhao Junping , Christopher Hurley , Jun Liang , Wendy Liu , Joseph P. Lyssikatos
IPC分类号： C07D471/04 , A61K31/496 , A61K31/5377 , A61P9/00 , A61P3/10 , A61P37/00 , A61P25/00 , A61P1/16 , A61P37/08 , A61P25/28 , A61P19/08 , A61P31/00 , A61P35/04 , A61P35/02 , A61P9/10 , A61P25/16 , A61P17/00 , A61K31/437
CPC分类号： C07D471/04 , A61K31/437 , A61K31/496 , A61K31/5377 , C07D487/04
摘要： A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are defined herein, are useful as JAK kinase inhibitors. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of JAK kinase activity in a patient are disclosed.

37. 发明申请

US20120202788A1 AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE 失效
标题翻译： AZABENZOTHIAZOLE化合物，组合物和使用方法
公开(公告)号：US20120202788A1
公开(公告)日：2012-08-09
申请号：US13232778
申请日：2011-09-14
申请人： Toby Jonathan Blench , Charles Ellwood , Simon Charles Goodacre , Yingjie Lai , Jun Liang , Calum Macleod , Steven R. Magnuson , Vickie H. Tsui , Karen Williams , Birong Zhang
发明人： Toby Jonathan Blench , Charles Ellwood , Simon Charles Goodacre , Yingjie Lai , Jun Liang , Calum Macleod , Steven R. Magnuson , Vickie H. Tsui , Karen Williams , Birong Zhang
IPC分类号： A61K31/437 , A61K31/506 , A61K31/5377 , A61K31/541 , A61P29/00 , A61P25/00 , A61P1/00 , A61P1/04 , A61P17/06 , A61P37/08 , A61P17/00 , A61P19/04 , C07D513/04 , A61P11/06
CPC分类号： A61K31/5377 , A61K31/437 , A61K31/501 , A61K31/506 , A61K31/519 , C07D513/04
摘要： Provided are compounds of Formula I, stereoisomers, tautomers, solvates, prodrugs and pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, R4 and R5 are defined herein, a pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, methods of using the compound or composition in therapy, and methods of manufacturing a compound of Formula I.
摘要翻译：提供式I化合物，立体异构体，互变异构体，溶剂合物，前药和药学上可接受的盐，其中A，X，R 1，R 2，R 4和R 5在本文中定义，药物组合物包括式I化合物和药学上可接受的载体，佐剂或载体，在治疗中使用化合物或组合物的方法，以及制备式I化合物的方法。

38. 发明授权

US08008317B2 Inhibitors of akt activtiy 有权
标题翻译：抑制剂的活性
公开(公告)号：US08008317B2
公开(公告)日：2011-08-30
申请号：US11921352
申请日：2006-06-07
申请人： Donna J. Armstrong , Essa H. Hu , Michael J. Kelly, III , Mark E. Layton , Yiwei Li , Jun Liang , Kevin J. Rodzinak , Michael J. Rossi , Philip E. Sanderson , Jiabing Wang
发明人： Donna J. Armstrong , Essa H. Hu , Michael J. Kelly, III , Mark E. Layton , Yiwei Li , Jun Liang , Kevin J. Rodzinak , Michael J. Rossi , Philip E. Sanderson , Jiabing Wang
IPC分类号： A61K31/437 , A61K31/4375 , C07D471/14 , C07D471/16
CPC分类号： C07D471/14 , C07D487/14
摘要： The instant invention provides for substituted naphthyridine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.
摘要翻译：本发明提供抑制Akt活性的取代的萘啶化合物。特别地，所公开的化合物选择性地抑制一种或两种Akt同种型。本发明还提供了包含这种抑制化合物的组合物和通过将该化合物给予需要治疗癌症的患者来抑制Akt活性的方法。

39. 发明申请

US20110202669A1 Method for Network Domain Name Resolution and the Resolution Device Thereof 有权
标题翻译：网络域名解析方法及其解决方法
公开(公告)号：US20110202669A1
公开(公告)日：2011-08-18
申请号：US13058532
申请日：2008-10-30
申请人： Jun Liang , Yuan Lin
发明人： Jun Liang , Yuan Lin
IPC分类号： G06F15/16
CPC分类号： H04L29/12066 , H04L12/6418 , H04L29/12594 , H04L61/1511 , H04L61/303
摘要： The invention relates to a method for network domain name resolution, the domain name comprises a first portion domain name and a second portion domain name, and the resolution method comprising following steps: In a first network system, resolving the first portion domain name into a first network address; In the first network system, searching for a first network node corresponding to the first network address according to the resolved first network address; In a second network system, resolving the second portion domain name into a second network node address, and the domain name resolution system of the second network system being independent of the domain name resolution system of the first network system. As the resolution structure of the domain name in the Intranet is independent of the resolution structure of the domain name in the Internet, the IP address of the Intranet will not occupy the IP address resource of the Internet.
摘要翻译：本发明涉及一种网络域名解析方法，该域名包括第一部分域名和第二部分域名，该解析方法包括以下步骤：在第一网络系统中，将第一部分域名解析为第一个网络地址; 在第一网络系统中，根据解决的第一网络地址搜索对应于第一网络地址的第一网络节点; 在第二网络系统中，将第二部分域名解析为第二网络节点地址，第二网络系统的域名解析系统独立于第一网络系统的域名解析系统。由于Intranet域名解析结构与互联网域名解析结构无关，因此Intranet的IP地址不会占用Internet的IP地址资源。

40. 发明授权

US07910561B2 Inhibitors of Akt activity 失效
标题翻译： Akt活性抑制剂
公开(公告)号：US07910561B2
公开(公告)日：2011-03-22
申请号：US11792121
申请日：2005-12-09
申请人： Jeannie M. Arruda , Brian T. Campbell , Nicholas D. P. Cosford , Jacob M. Hoffman , Essa H. Hu , Mark E. Layton , Yiwei Li , Jun Liang , Kevin J. Rodzinak , Tony Siu , Brian A. Stearns , Lida R. Tehrani , Mark T. Bilodeau , Peter J. Manley
发明人： Jeannie M. Arruda , Brian T. Campbell , Nicholas D. P. Cosford , Jacob M. Hoffman , Essa H. Hu , Mark E. Layton , Yiwei Li , Jun Liang , Kevin J. Rodzinak , Tony Siu , Brian A. Stearns , Lida R. Tehrani , Mark T. Bilodeau , Peter J. Manley
IPC分类号： A01N43/04 , A01N43/58 , A01N43/42 , A61K31/541 , A61K31/70 , A61K31/50 , A61K31/495 , A61K31/52 , C09B25/00 , C07D487/00 , C07D491/00 , C07H15/00
CPC分类号： C07D471/04
摘要： The present invention is directed to compounds which contain substituted naphthyridines which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention. These substituted naphthyridines have unexpected advantageous properties when compared to other naphthyridines reported in PCT publication WO2003/086394, such unexpected advantageous properties may include increased cellular potency/solubility, greater selectivity, enhanced pharmacokinetic properties, lack of off target activity and so on.
摘要翻译：本发明涉及含有抑制Akt（丝氨酸/苏氨酸蛋白激酶）活性的取代萘啶的化合物。本发明还涉及含有本发明化合物的治疗组合物和治疗癌症的方法，包括施用本发明化合物。与PCT公开WO2003 / 086394中报道的其它萘啶类相比，这些取代的萘啶具有意想不到的有利性质，这种意想不到的有利性质可包括增加的细胞效力/溶解度，更大的选择性，增强的药物动力学性质，缺乏目标活性等。

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