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31. 发明授权

US09284301B2 Soluble guanylate cyclase activators 有权
标题翻译：可溶性鸟苷酸环化酶活化剂
公开(公告)号：US09284301B2
公开(公告)日：2016-03-15
申请号：US13636760
申请日：2011-03-22
申请人： Darby Schmidt , Subharekha Raghavan , John Stelmach , Jian Guo , Jonathan Groeper , Linda Brockunier , Keith Rosauer , Hong Shen , Rui Liang , Fa-Xiang Ding
发明人： Darby Schmidt , Subharekha Raghavan , John Stelmach , Jian Guo , Jonathan Groeper , Linda Brockunier , Keith Rosauer , Hong Shen , Rui Liang , Fa-Xiang Ding
IPC分类号： C07D403/14 , C07D401/14 , C07D403/04 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04
CPC分类号： C07D403/14 , C07D401/14 , C07D403/04 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04
摘要： The invention relates to compounds having the structure of Formula (I) and pharmaceutically acceptable salts thereof, which are soluble guanylate cyclase activators. The compounds are capable of modulating the body's production of cyclic guanosine monophosphate (“cGMP”) and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The compounds are useful for treatment or prevention of cardiovascular diseases, endothelial dysfunction, diastolic dysfunction, atherosclerosis, hypertension, pulmonary hypertension, angina pectoris, thromboses, restenosis, myocardial infarction, strokes, cardiac insufficiency, pulmonary hypertonia, erectile dysfunction, asthma bronchiale, chronic kidney insufficiency, diabetes, or cirrhosis of the liver.
摘要翻译：本发明涉及具有式（I）结构的化合物及其药学上可接受的盐，它们是可溶性鸟苷酸环化酶活化剂。这些化合物能够调节人体的环鸟苷酸（“cGMP”）的产生，并且通常适用于治疗和预防与受干扰的cGMP平衡有关的疾病。该化合物可用于治疗或预防心血管疾病，内皮功能障碍，舒张功能障碍，动脉粥样硬化，高血压，肺动脉高压，心绞痛，血栓形成，再狭窄，心肌梗死，中风，心功能不全，肺性高血压，勃起功能障碍，支气管哮喘，慢性肾功能不全，糖尿病或肝硬化。

32. 发明申请

US20150173621A1 Imaging Fluorescence or Luminescence Lifetime 有权
标题翻译：成像荧光或发光寿命
公开(公告)号：US20150173621A1
公开(公告)日：2015-06-25
申请号：US14344507
申请日：2012-09-12
申请人： Jian Guo , Sameer Sonkusale
发明人： Jian Guo , Sameer Sonkusale
IPC分类号： A61B5/00 , G01N21/64
CPC分类号： A61B5/0071 , A61B5/444 , A61B5/6801 , G01J1/44 , G01J3/2803 , G01J3/4406 , G01N21/6408 , G01N21/6456 , G01N21/6486 , H01L27/1461
摘要： Among other things, devices for use in fluorescence or luminescence lifetime imaging are described. The devices include integrated complementary metal-oxide semiconductor (CMOS) chips that include an imaging region and a time-to-digital converter. The imaging region includes a photodetector for receiving optical signals. The time-to-digital converter provides digital phase output based on the received optical signals.
摘要翻译：其中，描述了用于荧光或发光寿命成像的装置。这些器件包括集成的互补金属氧化物半导体（CMOS）芯片，其包括成像区域和时间 - 数字转换器。成像区域包括用于接收光信号的光电检测器。时间到数字转换器基于接收的光信号提供数字相位输出。

33. 发明授权

US08728836B2 Method for preventing electrostatic breakdown, method for manufacturing array substrate and display substrate 有权
标题翻译：防止静电击穿的方法，阵列基板和显示基板的制造方法
公开(公告)号：US08728836B2
公开(公告)日：2014-05-20
申请号：US13338463
申请日：2011-12-28
申请人： Weifeng Zhou , Jian Guo , Xing Ming
发明人： Weifeng Zhou , Jian Guo , Xing Ming
IPC分类号： H01L21/00
CPC分类号： H01L27/0288 , H01L27/124
摘要： An embodiment of the disclosed technology provides a method for preventing electrostatic breakdown during the manufacturing process of the array substrate. The method comprises: when forming a conductive pattern of a substrate, connecting conductive lines for forming the conductive pattern with a closed conductive ring on a same layer as the conductive lines in a peripheral region of the substrate, and wherein when electrostatic charges are generated over the metal line, the electrostatic charges are led to the closed conductive ring.
摘要翻译：所公开的技术的一个实施例提供了一种在阵列基板的制造过程中防止静电破坏的方法。该方法包括：当形成衬底的导电图案时，在衬底的外围区域中，将与用于形成导电图案的导线连接在与导电线相同的层上的闭合导电环上，并且其中当静电电荷产生超过金属线路上，静电电荷被引导到封闭的导电环上。

34. 发明授权

US08692949B2 TFT-LCD array substrate wherein data line segments in adjacent pixel regions within a same column are connected by a first connection bar 有权
标题翻译： TFT-LCD阵列基板，其中同一列内的相邻像素区域中的数据线段通过第一连接条连接
公开(公告)号：US08692949B2
公开(公告)日：2014-04-08
申请号：US12749679
申请日：2010-03-30
申请人： Xin Zhao , Xing Ming , Weifeng Zhou , Wenyu Zhang , Jian Guo
发明人： Xin Zhao , Xing Ming , Weifeng Zhou , Wenyu Zhang , Jian Guo
IPC分类号： G02F1/136 , G02F1/1343
CPC分类号： H01L27/124 , G02F1/13624 , G02F2001/134318 , G02F2201/50 , G09G3/3614 , G09G3/3648 , G09G2300/0434 , G09G2300/0823 , G09G2320/0219 , G09G2320/0247 , H01L27/12 , H01L27/1214
摘要： A TFT-LCD array substrate, a manufacturing method thereof and a liquid crystal display panel are provided in the invention. The TFT-LCD array substrate comprises a plurality of first gate lines and a plurality of first data lines, and a plurality of pixel regions are defined by intersecting the first gate lines and the first data lines with each other. A first pixel electrode and a first TFT are formed in each of the pixel regions, and a second TFT and a second pixel electrode are further comprised in each of the pixel regions. The second TFT is connected with the second pixel electrode, the first pixel electrode and the second pixel electrode form the voltage difference to drive the reversion of the liquid crystal molecules, and the first TFT and the second TFT are turned on or off simultaneously.
摘要翻译：本发明提供TFT-LCD阵列基板及其制造方法和液晶显示面板。 TFT-LCD阵列基板包括多个第一栅极线和多个第一数据线，并且通过使第一栅极线和第一数据线彼此相交来限定多个像素区域。第一像素电极和第一TFT形成在每个像素区域中，并且第二TFT和第二像素电极还包括在每个像素区域中。第二TFT与第二像素电极连接，第一像素电极和第二像素电极形成电压差以驱动液晶分子的反转，并且第一TFT和第二TFT同时导通或截止。

35. 发明申请

US20130012511A1 SOLUBLE GUANYLATE CYCLASE ACTIVATORS 有权
标题翻译：可溶性冠状动脉激素
公开(公告)号：US20130012511A1
公开(公告)日：2013-01-10
申请号：US13636760
申请日：2011-03-22
申请人： Darby Schmidt , Subharekha Raghavan , John Stelmach , Jian Guo , Jonathan Groeper , Linda Brockunier , Keith Rosauer , Hong Shen , Rui Liang , Fa-Xiang Ding
发明人： Darby Schmidt , Subharekha Raghavan , John Stelmach , Jian Guo , Jonathan Groeper , Linda Brockunier , Keith Rosauer , Hong Shen , Rui Liang , Fa-Xiang Ding
IPC分类号： C07D403/14 , A61K31/506 , C07D471/04 , C07D401/14 , C07D413/14 , A61K31/5377 , C07D417/14 , C07D403/04 , A61P9/00 , A61P9/10 , A61P9/12 , A61P9/04 , A61P7/02 , A61P11/00 , A61P15/00 , A61P11/06 , A61P13/12 , A61P3/10 , A61P1/16 , A61P9/08 , A61P7/10 , A61P3/00 , A61P3/06 , C07D487/04
CPC分类号： C07D403/14 , C07D401/14 , C07D403/04 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04
摘要： The invention relates to compounds having the structure of Formula (I) and pharmaceutically acceptable salts thereof, which are soluble guanylate cyclase activators. The compounds are capable of modulating the body's production of cyclic guanosine monophosphate (“cGMP”) and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The compounds are useful for treatment or prevention of cardiovascular diseases, endothelial dysfunction, diastolic dysfunction, atherosclerosis, hypertension, pulmonary hypertension, angina pectoris, thromboses, restenosis, myocardial infarction, strokes, cardiac insufficiency, pulmonary hypertonia, erectile dysfunction, asthma bronchiale, chronic kidney insufficiency, diabetes, or cirrhosis of the liver.
摘要翻译：本发明涉及具有式（I）结构的化合物及其药学上可接受的盐，它们是可溶性鸟苷酸环化酶活化剂。这些化合物能够调节身体产生的环鸟苷酸（cGMP），通常适用于治疗和预防与受干扰的cGMP平衡有关的疾病。该化合物可用于治疗或预防心血管疾病，内皮功能障碍，舒张功能障碍，动脉粥样硬化，高血压，肺动脉高压，心绞痛，血栓形成，再狭窄，心肌梗死，中风，心功能不全，肺性高血压，勃起功能障碍，支气管哮喘，慢性肾功能不全，糖尿病或肝硬化。

36. 发明申请

US20120204058A1 Method and Device for Backing up User Information 有权
标题翻译：备份用户信息的方法和设备
公开(公告)号：US20120204058A1
公开(公告)日：2012-08-09
申请号：US13501606
申请日：2010-05-12
申请人： Bo Yuan , Liang Fan , Chengxu Zhu , Jian Guo
发明人： Bo Yuan , Liang Fan , Chengxu Zhu , Jian Guo
IPC分类号： G06F11/07 , G06F11/20
CPC分类号： H04L43/0811 , H04L41/0663 , H04L43/10
摘要： A method and apparatus for backing up user information are disclosed. The method includes: establishing a plurality of selection switch protocol groups between a same port of a standby service node and ports of a plurality of main service nodes respectively; the standby service node regularly receiving user information of access users from the ports of the plurality of main service nodes, and storing the user information to a main control unit of the standby service node; keeping a detection relation between the same port of the standby service node and the ports of the plurality of main service nodes; the standby service node sending to an interface unit of the standby service node the user information of the access user of that port stored in the main control unit, and according to the selection switch protocol, switching the same port of the standby service node to be main.
摘要翻译：公开了用于备份用户信息的方法和装置。该方法包括：分别在备用服务节点的同一端口和多个主服务节点的端口之间建立多个选择交换机协议组; 备用业务节点定期从多个主业务节点的端口接收接入用户的用户信息，并将用户信息存储到备用业务节点的主控单元; 保持备用服务节点的同一端口与多个主服务节点的端口之间的检测关系; 备用服务节点向备用服务节点的接口单元发送存储在主控单元中的该端口的接入用户的用户信息，并根据选择交换协议将备用业务节点的同一端口切换为主要。

37. 发明申请

US20100245700A1 TFT-LCD ARRAY SUBSTRATE, MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY PANEL 有权
标题翻译： TFT-LCD阵列基板，其制造方法和液晶显示面板
公开(公告)号：US20100245700A1
公开(公告)日：2010-09-30
申请号：US12749679
申请日：2010-03-30
申请人： Xin Zhao , Xing Ming , Weifeng Zhou , Wenyu Zhang , Jian Guo
发明人： Xin Zhao , Xing Ming , Weifeng Zhou , Wenyu Zhang , Jian Guo
IPC分类号： G02F1/1368
CPC分类号： H01L27/124 , G02F1/13624 , G02F2001/134318 , G02F2201/50 , G09G3/3614 , G09G3/3648 , G09G2300/0434 , G09G2300/0823 , G09G2320/0219 , G09G2320/0247 , H01L27/12 , H01L27/1214
摘要： A TFT-LCD array substrate, a manufacturing method thereof and a liquid crystal display panel are provided in the invention. The TFT-LCD array substrate comprises a plurality of first gate lines and a plurality of first data lines, and a plurality of pixel regions are defined by intersecting the first gate lines and the first data lines with each other. A first pixel electrode and a first TFT are formed in each of the pixel regions, and a second TFT and a second pixel electrode are further comprised in each of the pixel regions. The second TFT is connected with the second pixel electrode, the first pixel electrode and the second pixel electrode form the voltage difference to drive the reversion of the liquid crystal molecules, and the first TFT and the second TFT are turned on or off simultaneously.
摘要翻译：本发明提供TFT-LCD阵列基板及其制造方法和液晶显示面板。 TFT-LCD阵列基板包括多个第一栅极线和多个第一数据线，并且通过使第一栅极线和第一数据线彼此相交来限定多个像素区域。第一像素电极和第一TFT形成在每个像素区域中，并且第二TFT和第二像素电极还包括在每个像素区域中。第二TFT与第二像素电极连接，第一像素电极和第二像素电极形成电压差以驱动液晶分子的反转，并且第一TFT和第二TFT同时导通或截止。

38. 发明申请

US20090176854A1 PYRAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE 有权
标题翻译：吡唑衍生物，含有这些化合物的组合物和使用方法
公开(公告)号：US20090176854A1
公开(公告)日：2009-07-09
申请号：US12405600
申请日：2009-03-17
申请人： Emma R. Parmee , Yusheng Xiong , Jian Guo , Rui Liang , Linda Brockunier
发明人： Emma R. Parmee , Yusheng Xiong , Jian Guo , Rui Liang , Linda Brockunier
IPC分类号： A61K31/415 , A61P3/06
CPC分类号： C07D231/12 , C07D405/04
摘要： Pyrazoles having a naphthyl group attached are disclosed. The compounds are useful for treating type 2 diabetes and related conditions. Pharmaceutical compositions and methods of treatment are also included.
摘要翻译：公开了具有连接的萘基的吡唑。该化合物可用于治疗2型糖尿病及相关病症。还包括药物组合物和治疗方法。

39. 发明申请

US20080108620A1 Substituted Pyrazoles, Compositions Containing such Compounds and Methods of Use 有权
标题翻译：取代吡唑，含有这些化合物的组合物和使用方法
公开(公告)号：US20080108620A1
公开(公告)日：2008-05-08
申请号：US11632198
申请日：2005-07-19
申请人： Linda Brockunier , Jian Guo , Rui Liang , Emma R. Parmee , Subharekha Raghavan , George Scott Tria , Yusheng Xiong
发明人： Linda Brockunier , Jian Guo , Rui Liang , Emma R. Parmee , Subharekha Raghavan , George Scott Tria , Yusheng Xiong
IPC分类号： A61K31/4155 , A61K31/4184 , A61K31/423 , A61K31/428 , A61K31/4709 , A61K31/498 , A61P3/10 , A61P9/10 , C07D401/04 , C07D403/04 , C07D405/02 , C07D413/04 , C07D417/04
CPC分类号： C07D401/04 , C07D403/04 , C07D405/04 , C07D407/04 , C07D413/04 , C07D417/04
摘要： The present invention relates to substituted pyrazoles, compositions containing such compounds and methods of treatment. The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.
摘要翻译：本发明涉及取代的吡唑，含有这些化合物的组合物和处理方法。该化合物是胰高血糖素受体拮抗剂，因此可用于治疗，预防或延缓2型糖尿病的发作。

40. 发明申请

US20070293648A1 Hyaluronic acid-retaining polymers 失效
标题翻译：透明质酸保留聚合物
公开(公告)号：US20070293648A1
公开(公告)日：2007-12-20
申请号：US11796609
申请日：2007-04-27
申请人： Heather Sheardown , Mark Beek , Jian Guo
发明人： Heather Sheardown , Mark Beek , Jian Guo
IPC分类号： C08G73/10 , C08G63/06
CPC分类号： C08F265/04 , C08B37/0072 , C08F283/12 , C08F289/00
摘要： Hyaluronic acid-retaining biopolymer is provided which exhibits low levels of protein adsorption and surface friction. The biopolymer is useful for incorporation in products, such as contact lenses, used in biological environments.
摘要翻译：提供透明质酸保留生物聚合物，其表现出低水平的蛋白质吸附和表面摩擦。生物聚合物可用于掺入生物环境中使用的产品，如隐形眼镜。

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