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31. 发明申请

US20120294946A1 MODULATOR 有权
标题翻译：调制器
公开(公告)号：US20120294946A1
公开(公告)日：2012-11-22
申请号：US13515884
申请日：2010-12-17
申请人： Christopher Scott , James Johnston , Shaun Spence , Danny McAuley , Francois Fay
发明人： Christopher Scott , James Johnston , Shaun Spence , Danny McAuley , Francois Fay
IPC分类号： A61K31/702 , A61P29/00 , A61P35/00 , A61P35/02 , A61P11/00 , A61P31/06 , A61P11/06 , A61P11/08 , A61P1/00 , A61P31/00 , A61P9/00 , A61P13/12 , A61P17/00 , A61P37/00 , A61P3/10 , A61P25/00 , A61K9/14 , B82Y5/00
CPC分类号： A61K47/48853 , A61K45/06 , A61K47/593 , A61K47/61 , A61K47/6921 , A61K47/6937 , A61K47/6939 , Y10S977/773 , Y10S977/906
摘要： There is provided a method for suppressing a pro-inflammatory immune response in a cell, comprising providing to a cell sialic acid or analogs thereof, wherein the sialic acid or analogs are presented by a substrate such that a pro-inflammatory immune response in a cell is suppressed or an anti-inflammatory immune response is increased in a cell. Further, there is provided a method of treatment of inflammatory disease in a subject in need thereof. There is also provided a drug delivery device and a biomaterial which can modulate the inflammatory response in a subject.
摘要翻译：提供了一种抑制细胞中促炎免疫应答的方法，包括提供给唾液酸或其类似物的细胞，其中唾液酸或类似物由底物呈递，使得细胞中的促炎免疫应答被抑制或抗细胞免疫应答增加。此外，提供了在有需要的受试者中治疗炎症性疾病的方法。还提供了可以调节受试者的炎症反应的药物递送装置和生物材料。

32. 发明授权

US08073125B2 Spatial audio conferencing 有权
标题翻译：空间音频会议
公开(公告)号：US08073125B2
公开(公告)日：2011-12-06
申请号：US11861238
申请日：2007-09-25
申请人： Zhengyou Zhang , James Johnston
发明人： Zhengyou Zhang , James Johnston
IPC分类号： H04M3/42
CPC分类号： H04M3/56 , H04M3/568
摘要： Audio in an audio conference is spatialized using either virtual sound-source positioning or sound-field capture. A spatial audio conference is provided between a local and remote parties using audio conferencing devices (ACDs) interconnected by a network. Each ACD captures spatial audio information from the local party, generates either one, or three or more, audio data streams which include the captured information, and transmits the generated stream(s) to each remote party. Each ACD also receives the generated audio data stream(s) transmitted from each of the remote parties, processes the received streams to generate a plurality of audio signals, and renders the signals to produce a sound-field that is perceived by the local party, where the sound-field includes the spatial audio information captured from the remote parties. A sound-field capture device is also provided which includes at least three directional microphones symmetrically configured about a center axis in a semicircular array.
摘要翻译：音频会议中的音频使用虚拟声源定位或声场捕获进行空间化。使用由网络互连的音频会议设备（ACD）在本地和远程方之间提供空间音频会议。每个ACD捕获来自本地方的空间音频信息，生成包括所捕获的信息的一个或三个或更多个音频数据流，并将生成的流发送到每个远程方。每个ACD还接收从每个远程方发送的生成的音频数据流，处理所接收的流以产生多个音频信号，并且使信号产生由本地方感知的声场，其中声场包括从远程方捕获的空间音频信息。还提供了一种声场捕获装置，其包括围绕半圆形阵列的中心轴对称配置的至少三个定向麦克风。

33. 发明申请

US20090269360A1 THERAPY 有权
标题翻译：治疗
公开(公告)号：US20090269360A1
公开(公告)日：2009-10-29
申请号：US12296704
申请日：2007-04-10
申请人： Shane Olwill , Christopher Scott , Julie Gormley , Jaquin Thomas , Roberta Burden , Darragh McMeel , James Johnston
发明人： Shane Olwill , Christopher Scott , Julie Gormley , Jaquin Thomas , Roberta Burden , Darragh McMeel , James Johnston
IPC分类号： A61K39/395 , A61K33/24 , A61K31/435 , A61K31/495 , A61K31/7088 , C12N9/50 , C12N9/99 , C12N5/06 , G01N33/574
CPC分类号： C07K16/28 , A61K31/00 , A61K39/3955 , A61K39/39558 , A61K2039/505 , C07K16/40 , C07K2317/76 , G01N33/57492 , A61K2300/00
摘要： The invention relates to a method of inhibiting chemotherapy induced upregulation of Cathepsin S on the surface of tumour cells, the method comprising the administration of a Cathepsin S inhibitor to said cells. Also provided is a therapy comprising an anti Cathepsin S antibody, in particular an anti-Cathepsin S antibody which does not inhibit the proteolytic effect of Cathepsin S but nevertheless inhibits angiogenesis and a combination treatment comprising a Cathepsin S inhibitor and a therapeutic agent.
摘要翻译：本发明涉及一种抑制化学疗法诱导肿瘤细胞表面组织蛋白酶S上调的方法，该方法包括向所述细胞施用组织蛋白酶S抑制剂。还提供了包含抗组织蛋白酶S抗体，特别是不抑制组织蛋白酶S的蛋白水解作用但仍然抑制血管生成并且包含组织蛋白酶S抑制剂和治疗剂的组合治疗的抗组织蛋白酶S抗体的治疗剂。

34. 发明申请

US20060115629A1 Fuser-oil sorbent electrophotographic toner receiver layer 有权
标题翻译：定影油吸附剂电子照相调色剂接收层
公开(公告)号：US20060115629A1
公开(公告)日：2006-06-01
申请号：US10999411
申请日：2004-11-30
申请人： Mridula Nair , Tamara Jones , Charles Bauer , Joseph Hoff , Scott Moose , Joseph Sedita , James Johnston
发明人： Mridula Nair , Tamara Jones , Charles Bauer , Joseph Hoff , Scott Moose , Joseph Sedita , James Johnston
IPC分类号： B41M5/00
CPC分类号： G03G7/0046 , G03G7/0013 , G03G7/004 , G03G7/0053 , Y10T428/24802 , Y10T428/252 , Y10T428/254 , Y10T428/273 , Y10T428/31573 , Y10T428/31587 , Y10T428/31797 , Y10T428/31899 , Y10T428/31902 , Y10T428/31928
摘要： The invention relates to an image receiving element comprising in order a support, at least one polyolefin resin coating and at least one toner receiver layer, wherein said toner receiver layer comprises a fuser-oil sorbent additive and a thermoplastic polymer and said additive is present in an amount of greater than 10% by weight of said layer.
摘要翻译：本发明涉及一种图像接收元件，其包括依次包括支撑体，至少一个聚烯烃树脂涂层和至少一个调色剂接收层，其中所述调色剂接收层包括定影油吸附剂添加剂和热塑性聚合物，并且所述添加剂存在于大于所述层的10重量％。

35. 发明申请

US20060041085A1 ALDEHYDE SCAVENGERS FOR PREPARING TEMPORARY WET STRENGTH RESINS WITH LONGER SHELF LIFE 有权
标题翻译：用于制备具有长寿命寿命的临时湿度强度树脂的ALDEHYDE SCAVENGERS
公开(公告)号：US20060041085A1
公开(公告)日：2006-02-23
申请号：US10919487
申请日：2004-08-17
申请人： Cornel Hagiopol , Yuping Luo , David Townsend , James Johnston
发明人： Cornel Hagiopol , Yuping Luo , David Townsend , James Johnston
IPC分类号： C08F8/32 , C08C19/22
CPC分类号： C08F8/28 , C08F8/48 , C08F8/44 , C08F220/56
摘要： Aldehyde scavengers which are adducts of choline or a choline salt and an optionally substituted acrylamide monomer can be used to stabilize glyoxalated polyacrylamide compositions and to provide supplementary cationic charges for the polymer backbone.
摘要翻译：作为胆碱或胆碱盐和任选取代的丙烯酰胺单体的加合物的醛清除剂可用于稳定乙二醛化聚丙烯酰胺组合物并为聚合物主链提供补充的阳离子电荷。

36. 发明申请

US20060012612A1 Systems and methods for sharing application data in a networked computing environment 有权
标题翻译：用于在网络计算环境中共享应用程序数据的系统和方法
公开(公告)号：US20060012612A1
公开(公告)日：2006-01-19
申请号：US10875615
申请日：2004-06-24
申请人： James Johnston , Mark Kressin , William Quinn
发明人： James Johnston , Mark Kressin , William Quinn
IPC分类号： G09G5/00
CPC分类号： G06F3/1462 , G09G2310/04
摘要： A system and method for facilitating application sharing in a networked environment is provided. Specifically, the system divides a display area on a host computer into a plurality of regions, with each region comprised of a predetermined number of current pixels. The system then evaluates current pixels within a selected region and compares them to corresponding pixels stored in memory. If the system determines that the value of the current pixel differs from the value of the stored corresponding pixel, all pixels within the region are sent to a receiving computer via a network. The receiving computer inserts the received region into a display such that it matches the display on the host computer from which the region originated.
摘要翻译：提供了一种用于促进网络环境中的应用共享的系统和方法。具体地说，系统将主计算机上的显示区域划分为多个区域，每个区域由预定数量的当前像素构成。然后，系统评估所选区域内的当前像素并将其与存储在存储器中的相应像素进行比较。如果系统确定当前像素的值与存储的相应像素的值不同，则该区域内的所有像素经由网络发送到接收计算机。接收计算机将接收到的区域插入到显示器中，使得它与主区域起源的主计算机上的显示器相匹配。

37. 发明申请

US20050289176A1 Application sharing smoothness 失效
标题翻译：应用共享平滑
公开(公告)号：US20050289176A1
公开(公告)日：2005-12-29
申请号：US10877903
申请日：2004-06-25
申请人： James Johnston , William Quinn , Kevin Solie
发明人： James Johnston , William Quinn , Kevin Solie
IPC分类号： G06F3/14 , G06F17/00
CPC分类号： G06F3/1462
摘要： A method, system and apparatus for application sharing smoothness when updating application screen imagery in an application sharing system. A shared application smoothness system can include an application sharing server configured for communicative coupling to multiple application sharing clients. The system further can include an application image update smoothness processor programmed to consolidate changes to adjacent image regions in an image of a shared application for transmission to the communicatively coupled application sharing clients in a single application image update interval. A shared application smoothness method can include the steps of detecting common shared image changes across multiple adjacent display regions of a shared application image and transmitting updates for the multiple adjacent display regions to communicatively coupled application sharing clients in a single image update interval.
摘要翻译：一种在应用程序共享系统中更新应用程序屏幕图像时应用程序共享平滑度的方法，系统和装置。共享应用平滑系统可以包括配置为与多个应用共享客户端进行通信耦合的应用共享服务器。该系统还可以包括应用图像更新平滑处理器，该应用程序图像更新平滑处理器被编程以整合在共享应用的图像中的相邻图像区域的改变，以在单个应用图像更新间隔中传送到通信耦合的应用共享客户端。共享应用平滑方法可以包括以下步骤：跨共享应用图像的多个相邻显示区域检测公共共享图像变化，并且在单个图像更新间隔中将多个相邻显示区域的更新发送到通信耦合的应用共享客户端。

38. 发明申请

US20050199557A1 Wet oxidation 有权
标题翻译：湿氧化
公开(公告)号：US20050199557A1
公开(公告)日：2005-09-15
申请号：US10518589
申请日：2003-06-24
申请人： James Johnston , Peter Northcote , Michael Richardson
发明人： James Johnston , Peter Northcote , Michael Richardson
IPC分类号： B01B1/00 , B09C1/08 , C02F1/72 , C02F1/78 , C02F11/08
CPC分类号： B01B1/005 , B09C1/08 , C02F1/725 , C02F1/78 , C02F11/08 , Y10S210/908 , Y10S210/917 , Y10S210/928
摘要： An oxidation process is described which involves subjecting a feedstock which contains oxidisable material to temperature, pressure and contact with an oxidant. Excess water and volatile oxidation products, such as carbon dioxide, formic acid and acetic acid, are removed in the vapour phase. A catalyst may be employed to increase the rate of reaction. Preferred catalysts include the transition metal ions. Advantageously, the process may be operated in a continuous manner wherein the feedstock is continuously introduced into a reactor and a vapour phase containing volatile oxidation products continuously removed. The process is particularly applicable to the treatment of consumer and industrial waste.
摘要翻译：描述了一种氧化方法，其包括使含有可氧化材料的原料经受温度，压力和与氧化剂接触。在气相中除去过量的水和挥发性氧化产物，如二氧化碳，甲酸和乙酸。可以使用催化剂来提高反应速率。优选的催化剂包括过渡金属离子。有利地，该方法可以以连续方式操作，其中将原料连续地引入反应器中，并且连续除去含有挥发性氧化产物的气相。该过程特别适用于消费和工业废物的处理。

39. 发明申请

US20050132045A1 Adaptive and configurable application sharing system using manual and automatic techniques 失效
标题翻译：使用手动和自动技术的自适应和可配置的应用程序共享系统
公开(公告)号：US20050132045A1
公开(公告)日：2005-06-16
申请号：US10737316
申请日：2003-12-16
申请人： Raymond Hornback , William Quinn , Mark Kressin , James Johnston , Amy Travis , Kevin Solie
发明人： Raymond Hornback , William Quinn , Mark Kressin , James Johnston , Amy Travis , Kevin Solie
IPC分类号： G06F9/445 , G06F15/173 , H04L12/24 , H04L29/08
CPC分类号： G06F9/44505 , H04L41/0816 , H04L41/0846 , H04L41/0883 , H04L41/22 , H04L67/10 , H04L67/306
摘要： Described is a method for adapting an application sharing system for a network of computers according to user specific requirements. The method includes dynamically configuring system components and manually implementing user specific preferences to achieve a better user experience than is possible in typical application sharing systems. Users can configure the application sharing system based on their individual needs, and may need to modify their settings based on changing operating environments or usage patterns. The application sharing system can be dynamically configured based on content, current tasks, and changes in network conditions. System administrators can configure the application sharing system according to their general needs without preempting the needs of an individual user.
摘要翻译：描述了根据用户特定要求来适应计算机网络的应用共享系统的方法。该方法包括动态地配置系统组件并手动实现用户特定的偏好以实现比在典型的应用共享系统中可能的更好的用户体验。用户可以根据个人需要配置应用程序共享系统，并且可能需要根据不断变化的操作环境或使用模式修改其设置。应用程序共享系统可以基于内容，当前任务和网络条件的变化进行动态配置。系统管理员可以根据自己的一般需求配置应用程序共享系统，而不需要抢占单个用户的需求。

40. 发明授权

US4636902A Crosstalk shielding assembly for addition to one head of a dual magnetic head assembly 失效
标题翻译：串扰屏蔽组件，用于添加到双磁头组件的一个头部
公开(公告)号：US4636902A
公开(公告)日：1987-01-13
申请号：US629122
申请日：1984-07-09
申请人： Warren L. Dalziel , Charles Flanigan , Donald V. Daniels , John S. Lee , James Johnston
发明人： Warren L. Dalziel , Charles Flanigan , Donald V. Daniels , John S. Lee , James Johnston
IPC分类号： G11B5/11 , G11B5/48 , G11B5/22
CPC分类号： G11B5/11 , G11B5/4893
摘要： A dual magnetic head assembly is provided with asymmetrical crosstalk shielding. One of the heads includes a pair of mu-metal washers sandwiching a copper washer, the stacked washers surrounding the portion of the head including the read-write gap. The washers are enclosed within a copper plated mu-metal cap having a central opening through which the gap-containing portion of the head projects for cooperation with a magnetic medium. The other head is unshielded.
摘要翻译：双磁头组件设置有不对称的串扰屏蔽。其中一个头部包括一对夹着铜垫圈的金属垫圈，围绕包括读写间隙的头部的堆叠垫圈。垫圈被封装在具有中心开口的镀铜多孔金属盖中，头部的间隙部分通过该中心开口突出以与磁性介质配合。另一头是非屏蔽的。

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