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    • 31. 发明申请
    • NEUROSTIMULATION SYSTEM FOR DEFINING A GENERALIZED IDEAL MULTIPOLE CONFIGURATION
    • 用于定义一般化理想多重配置的神经网络系统
    • US20120239109A1
    • 2012-09-20
    • US13420060
    • 2012-03-14
    • Dongchul Lee
    • Dongchul Lee
    • A61N1/372
    • A61N1/36185A61N1/37247
    • A system for a neurostimulator coupled to electrodes. The system comprises an input device configured for generating control signals. The system further comprising memory storing a first set of variable values defining a first spatial relationship between a central ideal pole of a first polarity and the plurality of electrodes, a second set of variable values defining a second spatial relationship respectively between four ideal poles of a second polarity and the first ideal pole, and a third set of variable values defining relative intensities between the four ideal poles. The system further comprises control circuitry configured for modifying the first variable values, the second variable values, and/or the third variable values, and generating stimulation parameter values defining relative amplitude values for the electrodes that emulate the ideal poles, and instructing the neurostimulator to convey electrical energy to the electrodes in accordance with the stimulation parameter values.
    • 耦合到电极的神经刺激器的系统。 该系统包括被配置为产生控制信号的输入装置。 该系统还包括存储器,其存储限定第一极性的中心理想极点和多个电极之间的第一空间关系的第一组可变值,第二组可变值分别定义在第一极性的四个理想极之间的第二空间关系 第二极性和第一理想极点,以及限定四个理想极点之间的相对强度的第三组可变值。 该系统还包括配置用于修改第一可变值,第二可变值和/或第三可变值的控制电路,以及产生限定模拟理想极点的电极的相对幅度值的刺激参数值,并且指示神经刺激器 根据刺激参数值将电能传送到电极。
    • 33. 发明授权
    • System and method for increasing relative intensity between cathodes and anodes of neurostimulation system using pulse slicing
    • 使用脉冲切片增加阴极和神经刺激系统阳极之间的相对强度的系统和方法
    • US08355798B2
    • 2013-01-15
    • US12612528
    • 2009-11-04
    • Dongchul Lee
    • Dongchul Lee
    • A61N1/08
    • A61N1/36146A61N1/0553A61N1/36167
    • A method and neurostimulation system for providing therapy to a patient is provided. A plurality of electrodes is placed adjacent to tissue of the patient. A plurality of first electrical pulses is delivered to a first set of the electrodes, at least a second electrical pulse is delivered to a second set of the electrodes during the deliverance of each of the first electrical pulses, and at least a third electrical pulse is delivered to a third set of the electrodes during the deliverance of each of the first electrical pulses. The first electrical pulses have a first polarity, and each of the second electrical pulse(s) and third electrical pulses(s) has a second a second polarity opposite to the first polarity. The second and third electrical pulses are temporarily offset from each other.
    • 提供了一种用于向患者提供治疗的方法和神经刺激系统。 多个电极邻近患者的组织放置。 多个第一电脉冲被传送到第一组电极,在每个第一电脉冲的释放期间,至少第二电脉冲被传送到第二组电极,并且至少第三电脉冲是 在每个第一电脉冲的释放期间传送到第三组电极。 第一电脉冲具有第一极性,并且第二电脉冲和第三电脉冲中的每一个具有与第一极性相反的第二极性。 第二和第三电脉冲彼此临时偏移。
    • 34. 发明申请
    • NEUROSTIMULATION SYSTEM AND METHOD WITH GRAPHICALLY MANIPULATABLE STIMULATION TARGET
    • 神经系统和方法与图形可控的刺激目标
    • US20120041518A1
    • 2012-02-16
    • US13197987
    • 2011-08-04
    • Chester KimDongchul Lee
    • Chester KimDongchul Lee
    • A61N1/08
    • A61N1/37247A61N1/36071A61N1/36182G06F19/3481G16H40/63
    • An external control device for use with a neurostimulation device having a plurality of electrodes carried by at least one neurostimulation lead. The external control device comprises a display screen configured for displaying at least one object relative to a graphical representation of the neurostimulation lead(s). The object(s) represents an abstraction of a stimulation target. The external control device further comprises detection circuitry configured for detecting an actuation event that includes placing at least one pointing element in proximity to the object(s). The external control device further comprises processing circuitry configured for manipulating the object(s) on the display screen in response to the detection of the actuation event, thereby modifying the stimulation target abstraction, and for generating a set of stimulation parameters that emulates the modified stimulation target abstraction. The external control device further comprises output circuitry configured for transmitting the set of stimulation parameters to the neurostimulation device.
    • 一种与神经刺激装置一起使用的外部控制装置,具有由至少一个神经刺激引线携带的多个电极。 外部控制装置包括被配置为相对于神经刺激引线的图形表示显示至少一个对象的显示屏幕。 对象表示刺激目标的抽象。 外部控制装置还包括被配置用于检测致动事件的检测电路,其包括将至少一个指示元件放置在物体附近。 外部控制装置还包括处理电路,其被配置为响应于激活事件的检测来操纵显示屏上的对象,由此修改刺激目标抽象,并且用于生成模拟修改刺激的一组刺激参数 目标抽象。 外部控制装置还包括被配置为将刺激参数集合发送到神经刺激装置的输出电路。
    • 37. 发明授权
    • Neurostimulation system for defining a generalized ideal multipole configuration
    • 用于定义广义理想多极配置的神经刺激系统
    • US08909350B2
    • 2014-12-09
    • US13420060
    • 2012-03-14
    • Dongchul Lee
    • Dongchul Lee
    • A61N1/372A61N1/36
    • A61N1/36185A61N1/37247
    • A system for a neurostimulator coupled to electrodes. The system comprises an input device configured for generating control signals. The system further comprising memory storing a first set of variable values defining a first spatial relationship between a central ideal pole of a first polarity and the plurality of electrodes, a second set of variable values defining a second spatial relationship respectively between four ideal poles of a second polarity and the first ideal pole, and a third set of variable values defining relative intensities between the four ideal poles. The system further comprises control circuitry configured for modifying the first variable values, the second variable values, and/or the third variable values, and generating stimulation parameter values defining relative amplitude values for the electrodes that emulate the ideal poles, and instructing the neurostimulator to convey electrical energy to the electrodes in accordance with the stimulation parameter values.
    • 耦合到电极的神经刺激器的系统。 该系统包括被配置为产生控制信号的输入装置。 该系统还包括存储器,其存储限定第一极性的中心理想极点和多个电极之间的第一空间关系的第一组可变值,第二组可变值分别定义在第一极性的四个理想极之间的第二空间关系 第二极性和第一理想极点,以及限定四个理想极点之间的相对强度的第三组可变值。 该系统还包括配置用于修改第一可变值,第二可变值和/或第三可变值的控制电路,以及产生限定模拟理想极点的电极的相对幅度值的刺激参数值,并且指示神经刺激器 根据刺激参数值将电能传送到电极。
    • 38. 发明授权
    • System and method for reducing excitability of dorsal root fiber by introducing stochastic background noise
    • 通过引入随机背景噪声降低背根纤维的兴奋性的系统和方法
    • US08812115B2
    • 2014-08-19
    • US12501127
    • 2009-07-10
    • Dongchul Lee
    • Dongchul Lee
    • A61N1/00A61N1/36
    • A61N1/36071
    • A method and neurostimulator for providing therapy to a patient is provided. In one technique, electrical background energy is conveyed to a first tissue region of the patient in accordance with stochastic parameter, thereby modulating the excitability of the first tissue region, and electrical stimulation energy is conveyed to the first tissue region when its excitability is modulated. In one example, the stimulation energy may be conveyed to a second tissue region of the patient, thereby therapeutically stimulating the second tissue region. In this case, the excitability of the first tissue region is decreased, thereby reducing any adverse effect that the conveyed stimulation energy has on the first tissue region. As another example, the conveyed stimulation energy stimulates the first tissue region, in which case, the excitability of the first tissue region may be increased, thereby enhancing the stimulation of the first tissue region by the conveyed stimulation energy.
    • 提供了一种用于向患者提供治疗的方法和神经刺激器。 在一种技术中,电背景能量根据随机参数传送到患者的第一组织区域,从而调节第一组织区域的兴奋性,并且当其兴奋性被调制时,电刺激能量被传送到第一组织区域。 在一个示例中,刺激能量可被传送到患者的第二组织区域,从而治疗性刺激第二组织区域。 在这种情况下,第一组织区域的兴奋性降低,从而减少所输送的刺激能量对第一组织区域的任何不利影响。 作为另一个例子,输送的刺激能量刺激第一组织区域,在这种情况下,可以增加第一组织区域的兴奋性,从而通过输送的刺激能量增强对第一组织区域的刺激。
    • 39. 发明申请
    • NEUROSTIMULATION SYSTEM AND METHOD FOR ROSTRO-CAUDALLY STEERING CURRENT USING LONGITUDINAL IDEAL MULTIPOLE CONFIGURATIONS
    • 神经系统和方法使用纵向理想的多重配置进行转向导向电流
    • US20120239110A1
    • 2012-09-20
    • US13420140
    • 2012-03-14
    • Dongchul LeeChangfang Zhu
    • Dongchul LeeChangfang Zhu
    • A61N1/372
    • A61N1/36185A61N1/36071A61N1/37247A61N1/37264
    • A system for an electrical neurostimulator coupled to a plurality of electrodes. The system comprises a user-controlled input device configured for generating directional control signals. The system further comprises control circuitry configured for sequentially defining a plurality of different ideal bipole/tripole configurations relative to the plurality of electrodes in response to the directional control signals, generating a plurality of stimulation parameter sets respectively corresponding to the plurality of ideal bipole/tripole configurations, each stimulation parameter set defining relative amplitude values for the plurality of electrodes that emulate the respective ideal bipole/tripole configuration, and instructing the electrical neurostimulator to convey electrical energy to the plurality of electrodes in accordance with the plurality of stimulation parameter sets.
    • 一种耦合到多个电极的电神经刺激器的系统。 该系统包括被配置用于产生方向控制信号的用户控制输入装置。 该系统还包括控制电路,其被配置为响应于方向控制信号相对于多个电极依次定义多个不同的理想的双极/三极配置,产生分别对应于多个理想的双极/三极的多个刺激参数集 配置,每个刺激参数集定义了模拟相应的理想双极/三极配置的多个电极的相对振幅值,以及指示电神经刺激器根据多个刺激参数集向多个电极传送电能。