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31. 发明授权

US5308664A Rapidly recoverable PTFE and process therefore 失效
标题翻译：因此快速回收PTFE和工艺
公开(公告)号：US5308664A
公开(公告)日：1994-05-03
申请号：US248887
申请日：1988-09-23
申请人： Wayne D. House , David J. Myers
发明人： Wayne D. House , David J. Myers
IPC分类号： B29C55/00 , B29C67/20 , C08J5/18 , F16L9/16 , B32B27/32 , B29D7/24
CPC分类号： C08J5/18 , B29C55/005 , B29C67/20 , B29K2027/18 , B29K2105/04 , C08J2327/18 , Y10S264/73 , Y10S428/91 , Y10T428/1328 , Y10T428/24628 , Y10T428/2913 , Y10T428/2975 , Y10T428/31544
摘要： This invention relates to porous polytetrafluoroethylene (hereinafter PTFE) materials having the property of rapid recovery and a method for producing these materials. The microstructure of the porous PTFE material consists of nodes interconnected by fibrils, substantially all of the fibrils having a bent or wavy appearance. Articles made from these materials are particularly suitable for use in the medical field, but are also useful in other areas such as filtration and fabric applications.
摘要翻译：本发明涉及具有快速回收性能的多孔聚四氟乙烯（以下称为PTFE）材料及其制造方法。多孔PTFE材料的微结构由通过原纤维互连的节点组成，基本上所有的原纤维具有弯曲或波浪状外观。由这些材料制成的制品特别适用于医疗领域，但也适用于其他领域，例如过滤和织物应用。

32. 发明申请

US20120310326A1 INTERIOR LINER FOR TUBES, PIPES, AND BLOOD CONDUITS 审中-公开
标题翻译：管道，管道和血液导管的内部衬管
公开(公告)号：US20120310326A1
公开(公告)日：2012-12-06
申请号：US13590077
申请日：2012-08-20
申请人： Carey V. Campbell , Alvaro J. Laguna , James D. Lewis , Mark E. Mayrand , David J. Myers
发明人： Carey V. Campbell , Alvaro J. Laguna , James D. Lewis , Mark E. Mayrand , David J. Myers
IPC分类号： A61F2/82 , A61F2/06
CPC分类号： A61F2/92 , A61B17/12022 , A61B17/12109 , A61B17/12118 , A61F2/07 , A61F2/90 , A61F2002/075 , A61F2002/30289 , A61F2210/0076 , A61F2220/0008 , A61F2220/0075 , A61F2230/0091 , B29C48/00 , B29C48/0012 , B29C48/0021 , B29C48/07 , B29C48/09 , B29C48/15 , B29C48/21 , B29C53/58 , B29C55/24 , B29C63/34 , B29K2027/18 , B29K2105/04 , B29K2995/0072 , B29L2023/007 , F16L11/12
摘要： A tube which circumferentially distends from its initial circumference upon the application of a circumferentially distending force such as applied by an internal pressure, and which exhibits minimal recoil following the removal of the circumferentially distending force. The tube preferably has a second circumference larger than the initial circumference which remains substantially unchanged by further increasing force once it has been achieved. Because of the distensible circumference and minimal recoil of the tube, the tube is useful as a liner for pipes and vessels and particularly for pipes and vessels having irregular internal surfaces to which the tube can smoothly conform. The tube is preferably made from porous PTFE with thin walls, in which form it is particularly useful as a liner for both living and prosthetic blood vessels and to line anastomoses between living and prosthetic blood vessels.
摘要翻译：在施加周向上的膨胀力（例如通过内部压力施加）上周向地从其初始周边延伸的管，并且在除去周向膨胀力之后表现出最小的反冲。该管优选地具有大于初始周长的第二圆周，其一旦达到，则通过进一步增加的力而保持基本上不变。由于管的可伸缩周长和最小的后坐力，管可用作管和容器的衬套，特别是用于具有不规则内表面的管和容器，管可以顺利地对准管。管优选地由具有薄壁的多孔PTFE制成，其中形式特别可用作活体和假体血管的衬垫，并且在活体和假体血管之间排列吻合。

33. 发明授权

US08221488B2 Intraluminal stent graft 有权
公开(公告)号：US08221488B2
公开(公告)日：2012-07-17
申请号：US12781373
申请日：2010-05-17
申请人： James D. Lewis , David J. Myers , Wayne D. House
发明人： James D. Lewis , David J. Myers , Wayne D. House
IPC分类号： A61M29/00
CPC分类号： A61F2/82 , A61F2/07 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2210/0014 , A61F2240/001 , A61L31/10 , C08L27/18
摘要： A method of making a tubular intraluminal graft in the form of a tubular diametrically adjustable stent having a tubular covering of porous expanded polytetrafluoroethylene which is less than 0.10 mm thick. The covering may be on the exterior surface of the stent, or on the interior surface of the stent, or both. The covering may be affixed to the stent by an adhesive which is preferably fluorinated ethylene propylene.

34. 发明申请

US20100217375A1 Intraluminal Stent Graft 有权
公开(公告)号：US20100217375A1
公开(公告)日：2010-08-26
申请号：US12781358
申请日：2010-05-17
申请人： James D. Lewis , David J. Myers , Wayne D. House
发明人： James D. Lewis , David J. Myers , Wayne D. House
IPC分类号： A61F2/06
CPC分类号： A61F2/82 , A61F2/07 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2210/0014 , A61F2240/001 , A61L31/10 , C08L27/18
摘要： A method of making an tubular intraluminal graft in the form of a tubular diametrically adjustable stent having a tubular covering of porous expanded PTFE which is less than 0.10 mm thick. The covering may be on the exterior surface of the stent, or on the interior surface of the stent, or both. The covering may be affixed to the stent by an adhesive which is preferably fluorinated ethylene propylene.

35. 发明授权

US07279208B1 Thin-wall polytetrafluoroethylene tube 失效
标题翻译：薄壁聚四氟乙烯管
公开(公告)号：US07279208B1
公开(公告)日：2007-10-09
申请号：US09510937
申请日：2000-02-22
申请人： Donald G. M. Goffena , David J. Myers
发明人： Donald G. M. Goffena , David J. Myers
IPC分类号： B29D22/00 , B29D23/00 , B32B1/08
CPC分类号： B29D23/18 , A61B17/3431 , A61F2/06 , A61F2/07 , A61F2002/072 , A61F2002/075 , A61F2250/0067 , A61L27/16 , A61L27/56 , A61L29/041 , A61L29/085 , A61L31/048 , A61L31/10 , B29C53/38 , B29C53/58 , B29C63/10 , B29C70/207 , B29C70/30 , B29D23/001 , B29K2027/18 , B29K2105/04 , B29K2105/048 , B29K2105/0827 , B29K2105/101 , B29K2305/12 , B29L2009/00 , B29L2022/022 , B29L2023/005 , B29L2023/007 , B29L2023/18 , B29L2031/14 , B29L2031/753 , B29L2031/7542 , B32B1/08 , B32B3/02 , B32B3/10 , B32B5/18 , B32B5/32 , B32B15/02 , B32B15/08 , B32B27/30 , F16L11/085 , Y10S623/90 , Y10T428/1352 , Y10T428/1355 , Y10T428/1362 , Y10T428/139 , Y10T428/1393 , Y10T428/1397 , Y10T428/31504 , Y10T428/3154 , Y10T428/31544 , C08L27/18
摘要： A thin-wall PTFE (polytetrafluoroethylene) tube in the form of a tube of porous expanded PTFE film wherein the porous PTFE film has a microstructure containing a multiplicity of fibrils. The thin-wall tube is used in a non-porous embodiment as the balloon portion of a balloon catheter. The thin-wall tube is not elastomeric; however, because of the thinness, strength and flexibility of the tube, it may be inserted into a body conduit in a collapsed state and then deployed from a catheter and inflated up to the maximum diameter of the thin-wall tube. The porous PTFE film is provided with a continuous layer of adhesive to provide the non-porous tube; the adhesive is preferably a thermoplastic and more preferably a thermoplastic fluoropolymer such as fluorinated ethylene propylene.
摘要翻译：多孔PTFE多孔膜的形式的薄壁PTFE（聚四氟乙烯）管，其中多孔PTFE膜具有包含多个原纤维的微结构。薄壁管用作非多孔实施例中的球囊导管的球囊部分。薄壁管不弹性; 然而，由于管的薄度，强度和柔韧性，其可以以折叠状态插入体导管中，然后从导管展开并充气至薄壁管的最大直径。多孔PTFE膜具有连续的粘合剂层以提供无孔管; 粘合剂优选为热塑性，更优选热塑性含氟聚合物，例如氟化乙烯丙烯。

36. 发明授权

US06704210B1 Bioprothesis film strip for surgical stapler and method of attaching the same 失效
标题翻译：用于外科缝合器的生物质膜片及其附着方法
公开(公告)号：US06704210B1
公开(公告)日：2004-03-09
申请号：US08993922
申请日：1997-12-18
申请人： David J. Myers
发明人： David J. Myers
IPC分类号： H01R909
CPC分类号： A61B17/07207 , A61B17/07292 , A61B2017/00238 , A61B2017/320052
摘要： A bioprosthesis sealing film strip is attached to a surgical stapler by passing a jaw of the stapler through openings formed in the ends of the strip. Following stapling the strip is released by making a cut from the opening to the edge of the strip. Alternatively, one end of the strip may be releasably secured to pins formed on the jaw.
摘要翻译：生物假体密封膜条通过使吻合器的钳口通过形成在条的端部的开口而附接到外科缝合器。在装订后，通过从开口到条边缘的切割来释放条带。或者，条的一端可以可释放地固定到形成在钳口上的销。

37. 发明授权

US06547815B2 Intraluminal stent graft 失效
公开(公告)号：US06547815B2
公开(公告)日：2003-04-15
申请号：US10083461
申请日：2002-02-25
申请人： David J. Myers
发明人： David J. Myers
IPC分类号： A61M2900
CPC分类号： A61F2/82 , A61F2/07 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2210/0014 , A61F2240/001 , A61L31/10 , C08L27/18
摘要： A tubular intraluminal graft in the form of a tubular diametrically adjustable stent having a tubular covering of porous expanded polytetrafluoroethylene which is less than 0.10 mm thick. The covering may be on the exterior surface of the stent, or on the interior surface of the stent, or both. The covering may be affixed to the stent by an adhesive which is preferably fluorinated ethylene propylene.

38. 发明授权

US06347632B1 Compliant simulated aortas, method for making same by adjusting durometer of materials, and method for testing heart valves 失效
标题翻译：合适的模拟主动脉，通过调节材料的硬度来制造其方法，以及心脏瓣膜测试方法
公开(公告)号：US06347632B1
公开(公告)日：2002-02-19
申请号：US07910970
申请日：1992-07-09
申请人： Carol E. Eberhardt , David J. Myers
发明人： Carol E. Eberhardt , David J. Myers
IPC分类号： A61B1900
CPC分类号： A61F2/2412
摘要： A method of creating a simulated aorta patterned from a natural aorta and having a preselected amount of compliance is disclosed. The dimensions of a simulated aortic root patterned according to the dimensions of a natural aorta are first selected and a mold provided. The amount of circumferential compliance desired in the simulated aorta is then selected, based on natural circumferential compliancies. A material such as silicone rubber formed of an elastomer and a filler is used to form the aorta, the durometer of the material being varied by varying the relative amount of the components, to provide the selected amount of circumferential compliance in a simulated aorta having the selected dimensions. The aorta is then formed curing the material in the mold for about 24 hours. Groups of simulated aortas so produced, sometimes having different sizes and/or compliancies are also disclosed. A method of testing non-stented valves using the aortas is included.
摘要翻译：公开了一种创建从天然主动脉图案化并具有预选量的顺应性的模拟主动脉的方法。首先选择根据天然主动脉的尺寸进行图案化的模拟主动脉根的尺寸，并提供模具。然后根据天然圆周顺应性选择模拟主动脉期望的圆周顺应量。使用由弹性体和填料形成的诸如硅橡胶的材料以形成主动脉，通过改变组件的相对量来改变材料的硬度，以在具有所述主动脉的模拟主动脉中提供选定量的圆周顺应性所选尺寸。然后使主动脉固化模具中的材料约24小时。如此生产的模拟主动脉组，有时具有不同的尺寸和/或顺应性。包括使用主动脉测试非支架瓣膜的方法。

39. 发明授权

US6159565A Thin-wall intraluminal graft 失效
标题翻译：薄壁管腔内移植
公开(公告)号：US6159565A
公开(公告)日：2000-12-12
申请号：US108963
申请日：1993-08-18
申请人： Carey V. Campbell , James D. Lewis , David J. Myers
发明人： Carey V. Campbell , James D. Lewis , David J. Myers
IPC分类号： A61B17/34 , A61F2/00 , A61F2/06 , A61L29/04 , A61L29/08 , A61L31/04 , A61L31/10 , B29C53/38 , B29C53/58 , B29C70/20 , B29C70/30 , F16L11/08 , B29D22/00
CPC分类号： A61L31/048 , A61B17/3431 , A61F2/07 , A61F2002/072 , A61F2002/075 , A61F2250/0067 , A61L29/041 , A61L29/085 , A61L31/10 , B29C53/38 , B29C53/58 , B29C70/207 , B29C70/30 , B29K2027/18 , B29K2105/04 , B29K2105/0827 , B29L2023/005 , B29L2031/7542 , F16L11/085 , Y10T428/13 , Y10T428/1328 , Y10T428/1352 , Y10T428/1369 , Y10T428/1379 , Y10T428/139 , Y10T428/1393 , Y10T428/1397 , Y10T428/31504 , Y10T428/31536 , Y10T428/3154 , Y10T428/31544 , C08L27/18
摘要： An intraluminal vascular graft in the form of a tube of porous expanded polytetrafluoroethylene film wherein the porous polytetrafluoroethylene film has a microstructure containing a multiplicity of fibrils oriented substantially parallel to each other. The tube has a wall thickness of less than about 0.25 mm and is made from at least one first layer and at least one second layer of porous polytetrafluoroethylene film, wherein the fibrils of the first and second layers are oriented substantially perpendicular to each other. Preferably the fibrils of the at least one first layer are oriented substantially parallel to the longitudinal axis of the tube and the fibrils of the at least one second layer of porous polytetrafluoroethylene film are oriented substantially circumferential to the tube. The first and second layers may be inner and outer layers respectively, or alternatively their relationship may be reversed. Alternatively, either of the first and second film layers may be replaced with alternative reinforcing components such as a braid or at least one reinforcing rib.
摘要翻译：以多孔膨体聚四氟乙烯膜管形式的管腔内血管移植物，其中多孔聚四氟乙烯膜具有包含相互平行取向的多个原纤维的微结构。该管具有小于约0.25mm的壁厚，并且由至少一个第一层和至少一层第二层多孔聚四氟乙烯膜制成，其中第一层和第二层的原纤维彼此基本垂直。优选地，至少一个第一层的原纤维基本上平行于管的纵向轴线定向，并且至少一个第二层多孔聚四氟乙烯膜的原纤维基本上圆周地取向管。第一层和第二层可以分别是内层和外层，或者它们的关系可以相反。或者，第一和第二膜层中的任一个可以用替代的增强部件例如编织物或至少一个加强肋来代替。

40. 发明授权

US5993489A Tubular intraluminal graft and stent combination 失效
标题翻译：管状腔内移植和支架组合
公开(公告)号：US5993489A
公开(公告)日：1999-11-30
申请号：US024239
申请日：1998-02-17
申请人： James D. Lewis , David J. Myers
发明人： James D. Lewis , David J. Myers
IPC分类号： A61L27/00 , A61F2/00 , A61F2/82 , A61L31/10 , A61F2/06
CPC分类号： A61F2/82 , A61L31/10 , A61F2/07 , A61F2002/072 , A61F2002/075 , A61F2240/001 , Y10T428/1352 , Y10T428/1369 , Y10T428/1376 , Y10T428/1397 , Y10T428/3154
摘要： A tubular intraluminal graft for repairing body conduits, made from at least one layer of porous expanded PTFE film that has a microstructure having fibrils oriented in at least two directions which are substantially perpendicular to each other. The tubular intraluminal graft has a wall thickness of less than about 0.25 mm and may have a longitudinally or helically oriented seamline. Additional reinforcing components such as reinforcing ribs or braids may also be provided.
摘要翻译：一种用于修复身体管道的管状腔内移植物，其由至少一层多孔的PTFE多孔膜制成，所述PTFE膜具有基本上彼此垂直的至少两个方向上具有原纤维取向的微结构。管状管腔内移植物具有小于约0.25mm的壁厚，并且可以具有纵向或螺旋形定向的接缝。还可以提供附加的增强部件，例如加强筋或编织物。

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