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31. 发明授权

US08579832B2 Joining of sensor guide wire 有权
标题翻译：连接传感器导丝
公开(公告)号：US08579832B2
公开(公告)日：2013-11-12
申请号：US12739326
申请日：2008-10-24
申请人： Pär Von Malmborg , Leif Smith
发明人： Pär Von Malmborg , Leif Smith
IPC分类号： A61B5/00 , A61B6/00 , A61M25/00
CPC分类号： A61B5/0215 , A61M25/09 , A61M2025/09108 , A61M2025/09133
摘要： There is a sensor guide wire (1) for intravascular measurements of physiological variables in a living body. The sensor guide wire (1) comprises at least two elongate sections, a first tubular elongate section (2) being tubular in the longitudinal direction of the sensor guide wire (1), and a second elongate section (3) that is adapted to be inserted a predetermined distance (5) into said first tubular section (2), a sensor element (10) provided in the distal part of said sensor guide wire (1), for measuring the physiological variable and to generate a sensor signal in response to said variable, at least one signal transmitting cable connected to the sensor element (10) to transmit sensor signals to a male connector provided in the proximal part of said sensor guide wire (1). The tubular section (2) is provided with at least one through-going opening (4) in a direction perpendicular to the longitudinal direction of the guide wire (1) and positioned a second predetermined distance (6) from one end of the tubular section (2), wherein the guide wire (1) comprises a locking member (7) to be fitted into the opening (4) in order to join the sections (2, 3) together when the second elongate section (3) is inserted into the tubular section (2).
摘要翻译：传感器导丝（1）用于生物体内生理变量的血管内测量。传感器导丝（1）包括至少两个细长部分，沿着传感器导丝（1）的纵向方向管状的第一管状细长部分（2）和适于成为将预定距离（5）插入所述第一管状部分（2）中，设置在所述传感器导丝（1）的远端部分中的传感器元件（10），用于测量生理变量并响应于所述变量，连接到所述传感器元件（10）的至少一个信号传输电缆将传感器信号发送到设置在所述传感器导丝（1）的近端部分中的公连接器。管状部分（2）在垂直于导丝（1）的纵向方向的方向上设置有至少一个贯穿开口（4），并且从管状部分的一端定位第二预定距离（6）（2），其中所述导丝（1）包括锁定构件（7），以在所述第二细长部分（3）插入时将所述锁定构件（7）装配到所述开口（4）中，以便将所述部分（2,3）管状部分（2）。

32. 发明申请

US20120172731A1 RAPID EXCHANGE GUIDE UNIT 审中-公开
标题翻译：快速交换指南
公开(公告)号：US20120172731A1
公开(公告)日：2012-07-05
申请号：US13395769
申请日：2010-09-14
申请人： Leif Smith
发明人： Leif Smith
IPC分类号： A61B5/0215 , A61B5/01 , A61M25/09
CPC分类号： A61B5/0215 , A61B5/02158 , A61B5/6852 , A61M2025/0002 , A61M2025/0183
摘要： Rapid exchange guide unit comprising an elongated support member 3, and a guide wire member (11) provided with a guide wire lumen (13) having a distal guide wire opening (15) and a proximal guide wire opening (17), the guide wire lumen is arranged close to the distal end of said elongated support member, and is adapted to receive a guide wire. The rapid exchange guide unit further comprises at least one sensor (19) arranged close to the distal end of the elongated support member, and being adapted to measure a parameter in a living body, and to generate a sensor signal in dependence of the measured parameter. The sensor signal is applied to a signal processing unit adapted to process the sensor signal and to generate a processed sensor signal.
摘要翻译：包括细长支撑构件3的快速交换引导单元和设置有具有远侧导丝开口（15）和近端导丝开口（17）的导丝管腔（13）的导丝构件（11），该导丝管腔布置成靠近所述细长支撑构件的远端，并且适于接收导丝。快速交换引导单元还包括至少一个布置在细长支撑构件的远端附近的传感器（19），并且适于测量活体中的参数，并且根据所测量的参数产生传感器信号。传感器信号被施加到适于处理传感器信号并产生经处理的传感器信号的信号处理单元。

33. 发明授权

US07967761B2 Sensor and guide wire assembly 有权
标题翻译：传感器和导丝组件
公开(公告)号：US07967761B2
公开(公告)日：2011-06-28
申请号：US11607120
申请日：2006-12-01
申请人： Leif Smith
发明人： Leif Smith
IPC分类号： A61B5/00
CPC分类号： A61B5/036 , A61B5/6851 , A61M25/09033 , A61M2025/0002
摘要： A sensor and guide wire assembly (21; 41; 61; 81) for intravascular measurements of a physiological variable in a living body includes a sensor element (22; 42; 62; 82) mounted at a distal sensor portion (23; 43; 63; 83) of a guide wire (24; 44; 64; 84), wherein the sensor portion exhibits a maximal cross-sectional dimension which is larger than a maximal cross-sectional dimension of guide wire portions (28, 30; 48, 50; 68, 70) located proximally of the sensor portion.
摘要翻译：用于生物体内生理变量的血管内测量的传感器和导丝线组件（21; 41; 61; 81）包括安装在远端传感器部分（23; 43; 43）处的传感器元件（22; 42; 62; 导线（24; 44; 64; 84）的最大横截面尺寸大于导丝部分（28,30; 48; 84）的最大截面尺寸， 50; 68,70）位于传感器部分的近侧。

34. 发明申请

US20070220986A1 Pressure sensor 有权
标题翻译：压力传感器
公开(公告)号：US20070220986A1
公开(公告)日：2007-09-27
申请号：US11384817
申请日：2006-03-21
申请人： Leif Smith , Sauli Tulkki
发明人： Leif Smith , Sauli Tulkki
IPC分类号： G01L9/06
CPC分类号： G01L9/0025 , B60C23/0408 , G01L9/008
摘要： A sensor and insertion assembly 2 is used for intravascular measurement of pressure in a living body. The assembly includes a sensor chip 6 having a substrate body 8 with a recess covered by a pressure sensitive film 10 thereby forming a cavity 12. A piezoelectric element, preferably in the form of a piezoelectric film 14, is arranged in connection with the pressure sensitive film, and energy is applied to the piezoelectric element such that acoustic waves are generated in the element. The piezoelectric element is arranged to generate an output signal, representing the pressure at the film, in dependence on the measured properties of the acoustic waves related to the deflection of the pressure sensitive film.
摘要翻译：传感器和插入组件2用于血管内测量活体内的压力。组件包括传感器芯片6，传感器芯片6具有衬底本体8，衬底本体8具有被压敏薄膜10覆盖的凹部，从而形成空腔12.压电元件优选为压电薄膜14，与压力敏感膜和能量被施加到压电元件，使得在该元件中产生声波。压电元件被布置成根据与压敏膜的偏转相关的声波的测量特性，产生表示膜上的压力的输出信号。

35. 发明授权

US06623418B2 Radiation source 失效
公开(公告)号：US06623418B2
公开(公告)日：2003-09-23
申请号：US09851430
申请日：2001-05-09
申请人： Leif Smith
发明人： Leif Smith
IPC分类号： A61N500
CPC分类号： A61N5/1001 , H01J35/32 , H01J2235/164
摘要： A miniaturized radiation device, having a support member in the form of a flexible sheet, and a circuit pattern of electrical contact pads and interconnecting conductor lines or leads provided on said support member. The pads are interconnected via said patterned lines. There is also a plurality of radiation chips electrically connected to selected ones of said pads. Preferably the device is wrapped around a core member, that may be a wire, such that the assembly is suitable for the insertion into a living body for the controlled administration of radiation at a therapy location.

36. 发明授权

US06241651B1 Miniaturized source of ionizing radiation and method of delivering same 失效
标题翻译：小型电离辐射源及其传送方法
公开(公告)号：US06241651B1
公开(公告)日：2001-06-05
申请号：US09379782
申请日：1999-08-24
申请人： Leif Smith , Carolina Ribbing
发明人： Leif Smith , Carolina Ribbing
IPC分类号： A61N500
CPC分类号： A61N5/1001 , H01J35/32
摘要： A method and apparatus of creating a miniaturized source of radiation and delivering radiation to a location such as a therapy location. The radiation source includes a member made of a material emitting electrons when energy is supplied to the member. There is an electron retarding member disposed opposite the electron emitting member, and the electron retarding member is made of a material emitting ionizing radiation when electrons are retarded therein. The radiation source is further provided on an elongated member in a distal region thereof, and the elongated member is insertable into the body.
摘要翻译：一种创建微型辐射源并将辐射传送到诸如治疗位置的位置的方法和装置。辐射源包括当能量被供应到构件时由发射电子的材料制成的构件。存在与电子发射部件相对设置的电子延迟部件，并且当电子被延迟时，电子阻挡部件由发射电离辐射的材料制成。辐射源还设置在其远端区域中的细长构件上，并且细长构件可插入体内。

37. 发明申请

US20100268038A1 REMOVABLE ENERGY SOURCE FOR SENSOR GUIDEWIRE 有权
标题翻译：传感器指南的可拆卸的能量源
公开(公告)号：US20100268038A1
公开(公告)日：2010-10-21
申请号：US12742025
申请日：2008-08-22
申请人： Leif Smith
发明人： Leif Smith
IPC分类号： A61B5/00
CPC分类号： A61B5/0215 , A61B5/0002 , A61B5/6851 , A61B2560/0214 , A61B2560/0443 , A61B2562/225 , A61M25/09 , H01R13/622 , H01R13/6683 , H01R13/6691 , H01R24/66 , H01R24/76 , H01R2103/00
摘要： A transmitter unit with an attachable energy source is provided for a sensor guidewire. The transmitter unit is adapted to be connected to a proximal end of a sensor guidewire provided, at its distal end, with a sensor to measure a physiological parameter inside a patient. In some embodiments, the transmitter unit is adapted to wirelessly communicate by a communication signal with a communication unit, arranged in connection with an external device, in order to transfer measured physiological data to the external device. The attachable energy source can be a battery pack or battery holder provided with connecting electrical connecting surfaces. Preferably, the connection is protected from penetrating fluids by a protective seal.
摘要翻译：为传感器导丝提供具有可附接能量的发射器单元。发射器单元适于连接到传感器导丝的近端，传感器导丝在其远端处设置有用于测量患者体内生理参数的传感器。在一些实施例中，发射机单元适于通过通信信号与通信单元进行无线通信，该通信单元与外部设备结合地布置，以将测量的生理数据传送到外部设备。可附接能源可以是具有连接电连接表面的电池组或电池座。优选地，通过保护性密封来保护连接不渗透流体。

38. 发明申请

US20100222661A1 JOINING OF SENSOR GUIDE WIRE 有权
标题翻译：传感器导线接线
公开(公告)号：US20100222661A1
公开(公告)日：2010-09-02
申请号：US12739326
申请日：2008-10-24
申请人： Pär Von Malmborg , Leif Smith
发明人： Pär Von Malmborg , Leif Smith
IPC分类号： A61B5/04
CPC分类号： A61B5/0215 , A61M25/09 , A61M2025/09108 , A61M2025/09133
摘要： There is a sensor guide wire (1) for intravascular measurements of physiological variables in a living body. The sensor guide wire (1) comprises at least two elongate sections, a first tubular elongate section (2) being tubular in the longitudinal direction of the sensor guide wire (1), and a second elongate section (3) that is adapted to be inserted a predetermined distance (5) into said first tubular section (2), a sensor element (10) provided in the distal part of said sensor guide wire (1), for measuring the physiological variable and to generate a sensor signal in response to said variable, at least one signal transmitting cable connected to the sensor element (10) to transmit sensor signals to a male connector provided in the proximal part of said sensor guide wire (1). The tubular section (2) is provided with at least one through-going opening (4) in a direction perpendicular to the longitudinal direction of the guide wire (1) and positioned a second predetermined distance (6) from one end of the tubular section (2), wherein the guide wire (1) comprises a locking member (7) to be fitted into the opening (4) in order to join the sections (2, 3) together when the second elongate section (3) is inserted into the tubular section (2).
摘要翻译：传感器导丝（1）用于生物体内生理变量的血管内测量。传感器导丝（1）包括至少两个细长部分，沿着传感器导丝（1）的纵向方向管状的第一管状细长部分（2）和适于成为将预定距离（5）插入所述第一管状部分（2）中，设置在所述传感器导丝（1）的远端部分中的传感器元件（10），用于测量生理变量并响应于所述变量，连接到所述传感器元件（10）的至少一个信号传输电缆将传感器信号发送到设置在所述传感器导丝（1）的近端部分中的公连接器。管状部分（2）在垂直于导丝（1）的纵向方向的方向上设置有至少一个贯穿开口（4），并且从管状部分的一端定位第二预定距离（6）（2），其中所述导丝（1）包括锁定构件（7），以在所述第二细长部分（3）插入时将所述锁定构件（7）装配到所述开口（4）中，以便将所述部分（2,3）管状部分（2）。

39. 发明申请

US20080132806A1 Sensor and guide wire assembly 有权
标题翻译：传感器和导丝组件
公开(公告)号：US20080132806A1
公开(公告)日：2008-06-05
申请号：US11607120
申请日：2006-12-01
申请人： Leif Smith
发明人： Leif Smith
IPC分类号： A61B5/00
CPC分类号： A61B5/036 , A61B5/6851 , A61M25/09033 , A61M2025/0002
摘要： A sensor and guide wire assembly (21; 41; 61; 81) for intravascular measurements of a physiological variable in a living body includes a sensor element (22; 42; 62; 82) mounted at a distal sensor portion (23; 43; 63; 83) of a guide wire (24; 44; 64; 84), wherein the sensor portion exhibits a maximal cross-sectional dimension which is larger than a maximal cross-sectional dimension of guide wire portions (28, 30; 48, 50; 68, 70) located proximally of the sensor portion.
摘要翻译：用于生物体内生理变量的血管内测量的传感器和导丝线组件（21; 41; 61; 81）包括安装在远端传感器部分（23; 43; 43）处的传感器元件（22; 42; 62; 导线（24; 44; 64; 84）的最大横截面尺寸大于导丝部分（28,30; 48; 84）的最大横截面尺寸， 50; 68,70）位于传感器部分的近侧。

40. 发明授权

US07331236B2 Pressure sensor 有权
标题翻译：压力传感器
公开(公告)号：US07331236B2
公开(公告)日：2008-02-19
申请号：US11384817
申请日：2006-03-21
申请人： Leif Smith , Sauli Tulkki
发明人： Leif Smith , Sauli Tulkki
IPC分类号： G01L7/00
CPC分类号： G01L9/0025 , B60C23/0408 , G01L9/008
摘要： A sensor and insertion assembly 2 is used for intravascular measurement of pressure in a living body. The assembly includes, a sensor chip 6 having a substrate body 8 with a recess covered by a pressure sensitive film 10 thereby forming a cavity 12. A piezoelectric element, preferably in the form of a piezoelectric film 14, is arranged in connection with the pressure sensitive film, and energy is applied to the piezoelectric element such that acoustic waves are generated in the element. The piezoelectric element is arranged to generate an output signal, representing the pressure at the film, in dependence on the measured properties of the acoustic waves related to the deflection of the pressure sensitive film.
摘要翻译：传感器和插入组件2用于血管内测量活体内的压力。组件包括传感器芯片6，传感器芯片6具有衬底本体8，衬底本体8具有由压敏膜10覆盖的凹部，从而形成空腔12。优选以压电膜14的形式的压电元件与压敏膜连接设置，并且能量被施加到压电元件，使得在该元件中产生声波。压电元件被布置成根据与压敏膜的偏转相关的声波的测量特性，产生表示膜上的压力的输出信号。

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