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    • 31. 发明授权
    • Quantitative opaque particle agglutination assay
    • 定量不透明粒子凝集试验
    • US4760030A
    • 1988-07-26
    • US649253
    • 1984-09-10
    • Paulette PetersonMartin Becker
    • Paulette PetersonMartin Becker
    • G01N33/543G01N33/564G01N33/68G01N33/546
    • G01N33/54346G01N33/564G01N33/6854Y10S436/805Y10S436/808Y10S436/909
    • A method is disclosed for determining the presence of a member of a specific binding pair ("sbp member") consisting of ligand and its homologous receptor in a sample suspected of containing the sbp member. The method comprises combining in an assay medium the sample and an opaque particle capable of agglutinating in the presence of the sbp member. The opaque particle has a particle size of from about 0.2 to 5.0 microns. Next, the assay medium is irradiated with light having a wavelength of from about 350 to 2000 nm, and the optical density of the assay medium is measured. A change in optical density indicates the presence of the sbp member in the sample. The method has particular application in the determination of an antibody in a sample, particularly an autoantibody, such as, for example, rheumatoid factor.
    • 公开了一种用于确定在怀疑含有sbp成员的样品中由配体及其同源受体组成的特异性结合对(“sbp成员”)的成员的存在的方法。 该方法包括在测定介质中混合样品和能够在sbp构件存在下凝集的不透明颗粒。 不透明颗粒具有约0.2至5.0微米的粒度。 接下来,用波长为约350〜2000nm的光照射测定介质,测定测定介质的光密度。 光密度的变化表示样品中sbp成员的存在。 该方法在测定样品中的抗体,特别是自身抗体(例如类风湿因子)中具有特别的应用。
    • 33. 发明申请
    • Providing a virtual connection for transmitting application data units
    • 提供用于传输应用数据单元的虚拟连接
    • US20170026366A1
    • 2017-01-26
    • US15287942
    • 2016-10-07
    • Jian WangMartin Becker
    • Jian WangMartin Becker
    • H04L29/06
    • H04L63/0853G06Q20/108H04L63/0281H04L63/0428H04L67/42H04W4/50H04W12/0023H04W12/06
    • Method, comprising authenticating one or more first clients by a server, authenticating one or more second clients by the server and providing at least one application data unit switching by the server such that, when a data packet having a control application data unit is received from one of the first clients at the server, the server sends a data packet having the control application data unit that the received data packet contains to at least one of the second clients, and/or that, when a data packet having a response application data unit is received from one of the second clients at the server, the server sends a data packet having the response application data unit that the received data packet contains to at least one of the first clients.
    • 一种方法,包括由服务器验证一个或多个第一客户端,由服务器认证一个或多个第二客户端,并提供由服务器切换的至少一个应用数据单元,使得当从第一客户端接收到具有控制应用数据单元的数据分组时 服务器中的第一个客户端之一,服务器将具有接收的数据分组所包含的控制应用数据单元的数据分组发送给第二客户端中的至少一个,和/或当具有响应应用数据的数据分组 从服务器的第二客户端之一接收单元,服务器将具有接收到的数据分组所包含的响应应用数据单元的数据分组发送给第一客户端中的至少一个。
    • 36. 发明授权
    • Establishing a connection between steam generator heating surfaces and a collector and/or distributor
    • 建立蒸汽发生器加热表面与收集器和/或分配器之间的连接
    • US07533633B2
    • 2009-05-19
    • US11631746
    • 2005-07-04
    • Martin BeckerDietmar HettkampRalf-Udo Husemann
    • Martin BeckerDietmar HettkampRalf-Udo Husemann
    • F22B37/10
    • F22B37/104F22B37/04F22B37/225F22G3/009Y10S122/16Y10T29/4935
    • The invention relates to the establishing of a connection between steam generator heating surfaces made of austenitic materials and a collector and/or distributor made of martensitic or ferritic materials or of a nickel-base alloy. In order to extend the expectation of serviceable life of the connection, the pipe nipple of the reservoir used as a collector or distributor is made of a nickel-base alloy and directly welded to the collector wall in such a manner that an axial gap remains between the connecting branch and the collector wall. In a connection of the aforementioned type between steam generator heating surfaces made of austenitic materials and the pipe nipple or the pipe nipple and the collector made of martensitic materials, the coefficient of expansion of the material of the pipe nipple has a particularly good effect upon the serviceable life of the entire connection.
    • 本发明涉及建立由奥氏体材料制成的蒸汽发生器加热表面与由马氏体或铁素体材料或镍基合金制成的收集器和/或分配器之间的连接。 为了延长连接的使用寿命的期望,用作收集器或分配器的储存器的管接头由镍基合金制成并且以这样的方式直接焊接到收集器壁上,使得轴向间隙保持在 连接分支和收集器壁。 在由奥氏体材料制成的蒸汽发生器加热面与管接头或管接头以及由马氏体材料制成的收集器之间的上述类型的连接中,管接头的材料的膨胀系数对 整个使用寿命的连接。
    • 38. 发明授权
    • Device for the continuous casting of metals, in particular steel material, to form elongated products in a multiple casting line
    • 用于连续铸造金属,特别是钢材的装置,以在多条铸造线中形成细长的产品
    • US07036557B2
    • 2006-05-02
    • US10528380
    • 2003-09-02
    • Thomas FestHerbert BrotzkiMartin BeckerAdolf Gustav Zajber
    • Thomas FestHerbert BrotzkiMartin BeckerAdolf Gustav Zajber
    • B22D11/053
    • B22D11/053
    • A device for the continuous casting of metals, especially steel material, to elongated products in a multistrand casting apparatus with a plurality of continuous casting molds which are oscillatingly driven in an oscillating frame (2) by means of leaf springs (4) whereby the leaf springs (4) extend transversely to the casting direction (1) and serve for guide and weight compensation. The smallest possible strand spacing “A” is provided for that on a longitudinal foundation frame (5) to housings (6a) in the form of compact flat cassettes (6) are secured one behind the other in the strand travel direction. In the housings upper and lower leaf spring pairs (4a; 4b) run transversely to the cast strands (3) and the oscillating strands (11) engage the leaf spring pairs (4a; 4b), whereby a front oscillating drive (11a) works synchronously with the rear oscillating drive (11b).
    • 一种用于在具有多个连续铸造模具的多股铸造装置中将金属,特别是钢材连续铸造成细长产品的装置,其通过板簧(4)在振荡框架(2)中被振荡地驱动,从而叶片 弹簧(4)横向延伸到铸造方向(1),用于引导和重量补偿。 在纵向基座框架(5)上提供最小的可能的间距“A”,以紧凑的扁平盒(6)的形式的壳体(6a)在线材行进方向上彼此固定。 在壳体上下板簧对(4a; 4b)横向于铸造股线(3)延伸,并且摆动股线(11)接合板簧对(4a; 4b),由此前振荡驱动 (11a)与后部振荡驱动器(11b)同步工作。
    • 40. 发明授权
    • Method for producing a polynucleotide for use in single primer
amplification
    • 生产用于单引物扩增的多核苷酸的方法
    • US5595891A
    • 1997-01-21
    • US555323
    • 1990-07-19
    • Samuel RoseLinda M. WesternMartin BeckerEdwin F. Ullman
    • Samuel RoseLinda M. WesternMartin BeckerEdwin F. Ullman
    • C07H21/04C12N15/09C12N15/10C12Q1/68C12P19/34
    • C12Q1/6853C12N15/10C12Q1/686
    • A method is disclosed for producing a single stranded polydeoxynucleotide having two segments that are non-contiguous and complementary with each other. The method comprises the steps of providing in combination (1) a polynucleotide having two non-contiguous, non-complementary nucleotide sequences S1 and S2 wherein S2 is 5' of S1 and is at least ten deoxynucleotides long and (2) an extender probe comprised of two deoxynucleotide sequences, wherein the sequence at the 3'-end of the extender probe is hybridizable with S1 and the other of the deoxynucleotide sequences is homologous to S2 and (b) extending the extender probe along the polynucleotide. The method can also comprise providing in the combination a polydoxynucleotide primer capable of hybridizing at least at its 3'-end with a nucleotide sequence complementary to S2 under conditions where (1) the extended extender probe is rendered single stranded, (2) the polydeoxynucleotide primer hybridizes with and is extended along the extended extender probe to form a duplex comprising extended primer, (3) the extended primer is dissociated from the duplex, and (4) the primer hybridizes with and is extended along the extended primer to form a duplex comprising extended primer, and repeating steps (3) and (4). The method finds particular application in the detection of polynucleotide analytes.
    • 公开了一种用于生产具有彼此不连续和互补的两个区段的单链多脱氧核苷酸的方法。 该方法包括以下步骤:组合(1)具有两个非连续的非互补核苷酸序列S1和S2的多核苷酸,其中S2是S1的5',长至少十个脱氧核苷酸,和(2) 的两个脱氧核苷酸序列,其中扩增物探针的3'末端的序列可与S1杂交,而另一个脱氧核苷酸序列与S2同源,并且(b)沿多核苷酸扩展扩增体探针。 该方法还可以包括提供能够在其3'末端与至少与S2互补的核苷酸序列的多核苷酸引物提供,其中(1)扩展扩增物探针是单链的,(2)多脱氧核苷酸 引物与扩展的扩增物探针杂交并延伸,以形成包含延伸引物的双链体,(3)延伸引物与双链体解离,和(4)引物与延伸引物杂交并延伸以形成双链体 包括延伸引物,并重复步骤(3)和(4)。 该方法在多核苷酸分析物的检测中具有特殊应用。