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31. 发明申请

US20060165138A1 Frequency doubling of semiconductor lasers to generate 300-600 nm light 审中-公开
标题翻译：半导体激光器的倍频产生300-600nm的光
公开(公告)号：US20060165138A1
公开(公告)日：2006-07-27
申请号：US11055882
申请日：2005-02-11
申请人： Alexander Kachanov , Sze Tan , Boris Kharlamov , Barbara Paldus
发明人： Alexander Kachanov , Sze Tan , Boris Kharlamov , Barbara Paldus
IPC分类号： H01S3/10 , H01S3/04
CPC分类号： H01S5/02248 , H01S5/0092 , H01S5/02438 , H01S5/06837
摘要： A novel control system for a simple and compact all-solid-state laser generating 300 nm to 600 nm nm light with continuously variable output power in the range from 1 mW to at least 120 mW. Single frequency radiation from an external cavity semiconductor laser is frequency doubled in, for example, a periodically poled MgO:LiNbO3 ridge waveguide. Our laser maintains a high quality TEM00 circular beam with M2
摘要翻译：一种用于简单紧凑的全固体激光器的新型控制系统，其产生300nm至600nmnm的光，其连续可变输出功率在1mW至至少120mW的范围内。来自外部腔半导体激光器的单频辐射在例如周期性极化的MgO：LiNbO 3脊波导中倍频。我们的激光器保持了具有M <2> <1.1的高品质TEM 圆形光束，并且非常低。在其输出功率范围内噪声小于0.06％。即使在长时间运行期间也能看到峰峰值输出功率变化小于0.1％。在一个示例中，在70mW的输出功率下操作时不会观察到转换效率的降低，并且激光具有5cm×8cm的小的占地面积。

32. 发明申请

US20060165137A1 Novel external cavity CW frequency doubling of semiconductor lasers to generate 300-600nm light 审中-公开
标题翻译：新型外腔CW倍频半导体激光器产生300-600nm光
公开(公告)号：US20060165137A1
公开(公告)日：2006-07-27
申请号：US11040889
申请日：2005-01-21
申请人： Alexander Kachanov , Boris Kharlamov , Sze Tan , Barbara Paldus
发明人： Alexander Kachanov , Boris Kharlamov , Sze Tan , Barbara Paldus
IPC分类号： H01S3/10 , H01S3/04
CPC分类号： H01S5/02248 , H01S5/0021 , H01S5/0092 , H01S5/02438 , H01S5/06837
摘要： A novel control system for a simple and compact all-solid-state laser generating 300 nm to 600 nm nm light with continuously variable output power in the range from 1 mW to at least 120 mW. Single frequency radiation from an external cavity semiconductor laser is frequency doubled in a periodically poled MgO:LiNbO3 waveguide. The laser maintains a high quality TEM00 circular beam with M2
摘要翻译：一种用于简单紧凑的全固体激光器的新型控制系统，其产生300nm至600nmnm的光，其连续可变输出功率在1mW至至少120mW的范围内。来自外部腔半导体激光器的单频辐射在周期性极化的MgO：LiNbO 3波导中倍频。激光器在整个输出功率范围内保持具有M≥2的高品质TEM 00圆形光束和小于0.06％的非常低的噪声。在长时间运行期间测量峰峰值输出功率变化小于0.1％。在一个示例中，在输出功率为70mW的操作下并没有观察到转换效率的劣化，并且激光器具有仅5×8cm的小占地面积。

33. 发明申请

US20060123884A1 System and method for gas analysis using doubly resonant photoacoustic spectroscopy 有权
标题翻译：使用双共振光声光谱法进行气体分析的系统和方法
公开(公告)号：US20060123884A1
公开(公告)日：2006-06-15
申请号：US11245748
申请日：2005-10-07
申请人： Mark Selker , Alfred Riddle , Barbara Paldus
发明人： Mark Selker , Alfred Riddle , Barbara Paldus
IPC分类号： G01N21/00
CPC分类号： G01N21/1702 , G01N2021/1704
摘要： A method for analyzing gas concentration using doubly resonant photoacoustic spectroscopy, and a doubly resonant photaoacoustic gas detector comprising: i) a continuous wave light beam whose wavelength coincides with an absorption wavelength of a gaseous analyte; ii) a closed path optical cavity having at least two reflective surfaces; iii) an acoustic resonator chamber contained within said optical cavity, and comprising an acoustic sensor for detecting sound waves generated by a gaseous analyte present within said chamber, the light beam passing sequentially into, through and out of said chamber, and being repeatedly reflected back and forth through said chamber, and being modulated at a frequency which is equal to or equal to one-half of an acoustic resonance frequency of said acoustic resonator chamber.
摘要翻译：一种使用双共振光声光谱分析气体浓度的方法，以及双谐振光声气体检测器，包括：i）连续波光束，其波长与气态分析物的吸收波长一致; ii）具有至少两个反射表面的封闭路径光腔; iii）包含在所述光学腔内的声学谐振腔，并且包括用于检测由所述室内存在的气态分析物产生的声波的声学传感器，所述光束顺序地通过，通过和离开所述腔室，并被反复反射回并通过所述腔室进行调制，并以等于或等于所述声谐振腔的声共振频率的二分之一的频率进行调制。

34. 发明申请

US20060084180A1 Method for increasing the dynamic range of a cavity enhanced optical spectrometer 审中-公开
标题翻译：增加腔增强型光谱仪的动态范围的方法
公开(公告)号：US20060084180A1
公开(公告)日：2006-04-20
申请号：US10966315
申请日：2004-10-14
申请人： Barbara Paldus , Bruce Richman , Alexander Kachanov , Eric Crosson
发明人： Barbara Paldus , Bruce Richman , Alexander Kachanov , Eric Crosson
IPC分类号： G01N24/00
CPC分类号： G01N21/3504 , G01N21/39
摘要： Target analytes present in low concentration as components in a gaseous admixture can be detected using a cavity enhanced optical spectrometer by a process comprising: i) identifying from the spectrum of the pure target analyte a series of absorption peaks free from spectral interference by peaks of any additional gaseous species which are present, the first member of the series being the strongest spectral absorption peak of said target analyte ii) identifying one or more successive peaks of the series which have an absorption that is weaker than the immediately previously identified peak of the series, iii) performing a spectral scan at the wavelengths of the peaks identified in steps i) and ii), and iv) calculating the concentration of the target analyte from the spectral scan of the admixture performed at the wavelength determined in step iii).
摘要翻译：以气体混合物中的组分存在的目标分析物可以使用空腔增强型光谱仪通过以下方法来检测，所述方法包括：i）从纯的目标分析物的光谱中鉴定出一系列没有光谱干扰的吸收峰，存在的另外的气体物质，该系列的第一个成员是所述目标分析物的最强光谱吸收峰。ii）识别该系列的一个或多个连续的峰，其吸收比紧接着之前鉴定的该序列峰，iii）在步骤i）和ii）中确定的峰的波长处执行光谱扫描，以及iv）从在步骤iii）中确定的波长执行的混合物的光谱扫描计算目标分析物的浓度。

35. 发明申请

US20060083284A1 Method for increasing the dynamic range of a cavity enhanced optical spectrometer 审中-公开
标题翻译：增加腔增强型光谱仪的动态范围的方法
公开(公告)号：US20060083284A1
公开(公告)日：2006-04-20
申请号：US10966309
申请日：2004-10-14
申请人： Barbara Paldus , Bruce Richman , Chris Rella , Guido Knippels
发明人： Barbara Paldus , Bruce Richman , Chris Rella , Guido Knippels
IPC分类号： H01S3/082
CPC分类号： H01S5/14 , H01S3/08 , H01S3/08004 , H01S3/109
摘要： A doubled, external cavity laser comprises an external cavity pump laser section and an extra-cavity frequency doubling section. The pump laser section comprises an edge-emitting, semiconductor chip having: i) an anti-reflection coating on the chip facet facing the cavity ii) a low reflectivity coating on the output facet of the cavity, iii) a wavelength selective element on the anti-reflection side of the chip for producing a single-mode output beam, iv) at least one lens on the output side of the chip which operates to collimate the chip output beam and direct it to the frequency doubling section. The doubling section comprises: i) a second harmonic generating crystal consisting of gray track resistant PPKTP, stoichiometric PPLT, MgO doped stoichiometric PPLN, or MgO doped congruent PPLN, ii) doubling optics configured such that the chip output beam makes from one up to four collinear passes through the doubling crystal, and the second harmonic generation achieved through multiple passes is constructive, iii) beam shaping optics to create a collimated, frequency doubled output beam.
摘要翻译：双腔外腔激光器包括外腔泵激光器部分和外腔倍频部分。泵激光器部分包括边缘发射半导体芯片，其具有：i）面向空腔的芯片面上的防反射涂层ii）在腔的输出端面上的低反射率涂层，iii）在该腔上的波长选择元件用于产生单模输出光束的芯片的防反射侧，iv）在芯片的输出侧上的至少一个透镜，其操作以准直芯片输出光束并将其引导到倍频部分。加倍部分包括：i）由灰色轨道阻抗PPKTP，化学计量PPLT，掺杂MgO的化学计量PPLN或掺杂MgO的全同性PPLN组成的二次谐波产生晶体，ii）配置为使得芯片输出光束从一个多达四个共线通过双晶体，并且通过多遍实现的二次谐波产生是建设性的，iii）光束整形光学器件以产生准直的倍频输出光束。

36. 发明授权

US06967976B2 Laser with reflective etalon tuning element 失效
标题翻译：具有反光标准杆调谐元件的激光
公开(公告)号：US06967976B2
公开(公告)日：2005-11-22
申请号：US10909989
申请日：2004-08-03
申请人： Jinchun Xie , Alexandre Katchanov , Barbara Paldus
发明人： Jinchun Xie , Alexandre Katchanov , Barbara Paldus
IPC分类号： G02F1/35 , G02F1/37 , H01S5/14 , H01S3/10 , H01S3/08
CPC分类号： G02F1/37 , G02F1/3501 , G02F1/3544 , G02F2001/3503 , G02F2201/17 , H01S5/141 , H01S5/142
摘要： A tunable laser and laser tuning method based on the use of a tunable etalon in reflection as a mirror within a laser cavity and forming an end reflective surface thereof. The laser emission wavelength is not necessarily at a wavelength of peak etalon reflectivity. A preferred embodiment makes use of a microelectromechanical etalon to tune an external cavity semiconductor.
摘要翻译：一种可调谐激光和激光调谐方法，其基于在激光腔内的反射镜中使用可调标准具并形成其端部反射表面。激光发射波长不一定在标准具有峰值反射率的波长。优选的实施例利用微机电标准具来调谐外腔半导体。

37. 发明申请

US20050008045A1 Laser with reflective etalon tuning element 失效
公开(公告)号：US20050008045A1
公开(公告)日：2005-01-13
申请号：US10909989
申请日：2004-08-03
申请人： Jinchun Xie , Alexandre Katchanov , Barbara Paldus
发明人： Jinchun Xie , Alexandre Katchanov , Barbara Paldus
IPC分类号： G02F1/35 , G02F1/37 , H01S5/14 , H01S3/10 , H01S3/08
CPC分类号： G02F1/37 , G02F1/3501 , G02F1/3544 , G02F2001/3503 , G02F2201/17 , H01S5/141 , H01S5/142
摘要： A tunable laser and laser tuning method based on the use of a tunable etalon in reflection as a mirror within a laser cavity and forming an end reflective surface thereof. The laser emission wavelength is not necessarily at a wavelength of peak etalon reflectivity. A preferred embodiment makes use of a microelectromechanical etalon to tune an external cavity semiconductor.

38. 发明授权

US06611546B1 Optical transmitter comprising a stepwise tunable laser 有权
标题翻译：光发射机包括逐步可调激光器
公开(公告)号：US06611546B1
公开(公告)日：2003-08-26
申请号：US09930841
申请日：2001-08-15
申请人： Arnaud Garnache , Daniele Romanini , Frederic Stoeckel , Alexandre Katchanov , Guido Knippels , Barbara Paldus , Christopher Rella , Bruce Richman , Marc Levenson
发明人： Arnaud Garnache , Daniele Romanini , Frederic Stoeckel , Alexandre Katchanov , Guido Knippels , Barbara Paldus , Christopher Rella , Bruce Richman , Marc Levenson
IPC分类号： H01S308
CPC分类号： H01S5/02288 , H01S3/1062 , H01S5/0217 , H01S5/041 , H01S5/0687 , H01S5/141 , H01S5/18361 , H01S5/18375 , H01S5/18377
摘要： An optical fiber transmitter for emitting an information-carrying laser beam comprises an optically or electrically pumped single mode MQW (multi quantum well) semiconductor amplifying mirror as a gain medium and a separate external reflector to form a cavity. The external cavity length defines a comb of optical modes, all or a subset of which corresponding to channel wavelengths of an optical telecommunications system having plural optical channels. The semiconductor gain element has a homogeneously broadened gain region; a tuning arrangement tunes the laser from mode to mode across the gain region thereby selecting each one of the plural optical channels. When the maximum gain bandwidth is less than mode-to-mode spacing defined by the cavity, that tuning arrangement comprises a means of altering the temperature of the amplifying mirror, thereby translating the frequency of the gain peak from one mode to another. An optical modulator adds modulation to a beam emitting from the laser to provide the information-carrying laser beam, and a coupler couples the information-carrying laser beam into an optical fiber of the optical telecommunications system. A calibration method based on detecting inter-mode optical transitions (mode hopping) is described. The parameters of the amplifying mirror and tuning arrangement can be adjusted during operation to switch quickly from one cavity mode to another in stepwise fashion.
摘要翻译：用于发射信息载体的激光束的光纤发射器包括光学或电泵浦的单模MQW（多量子阱）半导体放大镜作为增益介质和单独的外部反射器以形成空腔。外部空腔长度定义了光学模式梳，其全部或一部分对应于具有多个光学通道的光通信系统的通道波长。半导体增益元件具有均匀加宽的增益区域; 调谐装置将激光从模式调谐到增益区域，从而选择多个光通道中的每一个。当最大增益带宽小于由空腔限定的模 - 模间隔时，该调谐装置包括改变放大镜的温度的装置，从而将增益峰值的频率从一种模式转换到另一种模式。光调制器向从激光器发射的光束增加调制以提供信息传送激光束，并且耦合器将信息传送激光束耦合到光通信系统的光纤中。描述了基于检测模式间转换（跳频）的校准方法。在操作期间可以调节放大镜和调谐装置的参数，以逐步的方式从一个腔模式快速切换到另一腔模式。

39. 发明授权

US08008065B2 Disposable bioreactor vessel port 有权
标题翻译：一次性生物反应器血管口
公开(公告)号：US08008065B2
公开(公告)日：2011-08-30
申请号：US11728560
申请日：2007-03-26
申请人： Mark Selker , Timothy Johnston , Barbara Paldus
发明人： Mark Selker , Timothy Johnston , Barbara Paldus
IPC分类号： C12M1/34 , C12M1/26 , G01N1/10
CPC分类号： C12M23/00
摘要： A port for use with a bioreactor vessel comprising: i) a base member comprising a hollow tubular portion and a base plate configured to be sealingly affixed to a hole in the wall of a bioreactor vessel ii) a hollow, generally tubular bushing member for containing electrical, optical, microfluidic and/or chemical monitoring components which bushing member fits inside the bore of the tubular portion of the base member, both the base member and bushing member providing access to the contents of a bioreactor by; iii) a monitoring assembly inserted into the bushing member which assembly comprises means for providing incoming optical and/or electrical signals and means for collecting and transmitting measurement signals resulting from the interaction of incoming optical and/or electrical signals with the contents of a bioreactor; and iv) a cover which maintains the position and alignment of components ii) and iii) relative to the base member.
摘要翻译：一种用于生物反应器容器的端口，包括：i）基部构件，其包括中空管状部分和底板，所述基座构造成密封地固定到生物反应器容器的壁的孔中ii）中空的大体管状衬套构件，电气，光学，微流体和/或化学监测部件，衬套构件配合在基部构件的管状部分的孔内，基部构件和衬套构件都提供通过生物反应器的内容物的通路; iii）监测组件，其插入到衬套构件中，该组件包括用于提供输入光学和/或电信号的装置，以及用于收集和传送由输入光学和/或电信号与生物反应器的内容物相互作用而产生的测量信号的装置; 以及iv）保持组件ii）和iii）相对于基座构件的位置和对准的盖。

40. 发明授权

US07824902B2 Optical interface for disposable bioreactors 有权
标题翻译：一次性生物反应器的光学接口
公开(公告)号：US07824902B2
公开(公告)日：2010-11-02
申请号：US11725255
申请日：2007-03-17
申请人： Mark Selker , Benjamin Blizard , Timothy Johnston , Barbara Paldus
发明人： Mark Selker , Benjamin Blizard , Timothy Johnston , Barbara Paldus
IPC分类号： C12M1/34
CPC分类号： C12M23/14 , C12M29/00 , C12M41/26 , C12M41/32 , C12M41/34
摘要： A port assembly for use with a polymeric bioreactor bag includes the following components: i) a hollow port member made from a material which can be fusibly affixed to the wall surface of the bioreactor bag; ii) at least one fluorophore spot positioned on the port member; iii) a conduit for conveying excitation light from an optical source to the fluorophore, which conduit can be a lens, a curved parabolic collimator, a shaped reflector or a wave guide; and iv) a second conduit for conveying fluorescent emission light from the excited fluorophore to a photo-detector, which second conduit although different from the first, can likewise be a lens, a curved parabolic collimator, a shaped reflector or a wave guide.
摘要翻译：与聚合物生物反应器袋一起使用的端口组件包括以下部件：i）由材料制成的中空端口部件，该材料可以柔软地固定在生物反应器袋的壁表面上; ii）位于端口构件上的至少一个荧光团斑点; iii）用于将激发光从光源传输到荧光团的导管，该导管可以是透镜，弯曲抛物线准直器，成形反射器或波导管; 以及iv）用于将来自激发的荧光团的荧光发射光传送到光检测器的第二导管，该第二导管虽然不同于第一导管，但也可以是透镜，弯曲的抛物线准直器，成形反射器或波导。

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