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31. 发明申请

US20130020562A1 POLYMER COMPOUND, NET-LIKE POLYMER COMPOUND PRODUCED BY CROSSLINKING THE POLYMER COMPOUND, COMPOSITION FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC EL DISPLAY, AND ORGANIC EL LIGHTING 有权
标题翻译：聚合物化合物，通过交联聚合物化合物生产的网状聚合物化合物，有机电致发光元件的组合物，有机电致发光元件，有机EL显示器和有机EL照明
公开(公告)号：US20130020562A1
公开(公告)日：2013-01-24
申请号：US13617286
申请日：2012-09-14
申请人： Koichiro IIDA , Kyoko Endo , Yanjun Li , Kazuki Okabe , Masayoshi Yabe
发明人： Koichiro IIDA , Kyoko Endo , Yanjun Li , Kazuki Okabe , Masayoshi Yabe
IPC分类号： C08G73/02 , H01L51/54
CPC分类号： H01L51/0039 , C08G61/12 , C08G73/02 , C08G73/026 , C08G2261/135 , C08G2261/141 , C08G2261/1424 , C08G2261/3142 , C08G2261/3162 , C08G2261/512 , C08G2261/76 , C08L79/02 , C09B69/008 , C09B69/101 , H01L51/0035 , H01L51/0043 , H01L51/5048
摘要： An object of the invention is to provide a polymer compound having a high hole transport capacity, excellent in electrochemical stability, and suitable to film formation according to a wet film formation method. Another object of the invention is to provide an organic electroluminescence element having a high current efficiency, a low drive voltage, and a long derive lifetime. The polymer compound has a crosslinking group bonding to the arylamine moiety in the repeating unit via at least one single bond therebetween.
摘要翻译：本发明的目的是提供一种具有高空穴传输能力，优异的电化学稳定性，适用于根据湿膜形成方法的成膜的高分子化合物。本发明的另一个目的是提供一种具有高电流效率，低驱动电压和长导出寿命的有机电致发光元件。高分子化合物具有通过其间的至少一个单键与重复单元中的芳基胺部分结合的交联基团。

32. 发明申请

US20120208756A1 COMPOSITION FOR EXTERNAL PREPARATION FOR SKIN 审中-公开
标题翻译：用于皮肤外用制剂的组合物
公开(公告)号：US20120208756A1
公开(公告)日：2012-08-16
申请号：US13386528
申请日：2010-07-23
申请人： Kyoko Endo
发明人： Kyoko Endo
IPC分类号： A61K38/22 , A61P37/08 , A61P17/00
CPC分类号： A61K38/2242 , A61K8/64 , A61K9/0014 , A61K9/06 , A61K38/22 , A61Q1/02 , A61Q17/04 , A61Q19/00 , A61Q19/10
摘要： The problem to be solved by the present invention is to provide a safe and efficacious therapeutic agent for dermatitis which is not only safe and efficacious for patients with dermatitis, in particular atopic dermatitis, but also significantly effective for severe cases that are judged to be intractable by conventional external preparations, and which is also safely applicable to affected areas such as the face and neck, as well as to subjects with sensitive skin, such as infants and females. Furthermore, the invention aims to provide an external preparation that is efficacious as skin care cosmetics having effects to improve elasticity and wrinkles of the skin, moisturizing effects, and hair-growth effects.The means for solving the problem is a skin external-preparation composition, in particular, a therapeutic agent for dermatitis or a skin texture-improving agent, having C-type natriuretic peptide (CNP) or B-type natriuretic peptide (BNP) as the active ingredient.
摘要翻译：本发明要解决的问题是提供一种安全有效的皮炎治疗剂，其不仅对于皮炎特别是特应性皮炎的患者是安全有效的，而且对于被判断为难治性的严重病例也是显着有效的通过常规的外用制剂，也可以安全地应用于受影响的区域，例如面部和颈部，以及敏感皮肤的受试者，例如婴儿和女性。此外，本发明的目的是提供作为护肤化妆品有效的外用制剂，其具有改善皮肤的弹性和皱纹，保湿效果和毛发生长作用的效果。解决问题的手段是皮肤外用剂组合物，特别是皮炎或皮肤纹理改善剂治疗剂，其具有C型利尿钠肽（CNP）或B型利钠肽（BNP）作为有效成分。

33. 发明申请

US20110108814A1 POLYMER COMPOUND, NET-LIKE POLYMER COMPOUND PRODUCED BY CROSSLINKING THE POLYMER COMPOUND, COMPOSITION FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC EL DISPLAY, AND ORGANIC EL LIGHTING 有权
标题翻译：聚合物化合物，通过交联聚合物化合物生产的网状聚合物化合物，有机电致发光元件的组合物，有机电致发光元件，有机EL显示器和有机EL照明
公开(公告)号：US20110108814A1
公开(公告)日：2011-05-12
申请号：US12936136
申请日：2009-04-01
申请人： Koichiro Iida , Kyoko Endo , Yanjun Li , Kazuki Okabe , Masayoshi Yabe
发明人： Koichiro Iida , Kyoko Endo , Yanjun Li , Kazuki Okabe , Masayoshi Yabe
IPC分类号： H01L51/54 , C08G73/02 , C08F14/18 , C08F26/02
CPC分类号： H01L51/0039 , C08G61/12 , C08G73/02 , C08G73/026 , C08G2261/135 , C08G2261/141 , C08G2261/1424 , C08G2261/3142 , C08G2261/3162 , C08G2261/512 , C08G2261/76 , C08L79/02 , C09B69/008 , C09B69/101 , H01L51/0035 , H01L51/0043 , H01L51/5048
摘要： An object of the invention is to provide a polymer compound having a high hole transport capacity, excellent in electrochemical stability, and suitable to film formation according to a wet film formation method. Another object of the invention is to provide an organic electroluminescence element having a high current efficiency, a low drive voltage, and a long derive lifetime. The polymer compound has a crosslinking group bonding to the arylamine moiety in the repeating unit via at least one single bond therebetween.
摘要翻译：本发明的目的是提供一种具有高空穴传输能力，优异的电化学稳定性，适用于根据湿膜形成方法的成膜的高分子化合物。本发明的另一个目的是提供一种具有高电流效率，低驱动电压和长导出寿命的有机电致发光元件。高分子化合物具有通过其间的至少一个单键与重复单元中的芳基胺部分结合的交联基团。

34. 发明授权

US07659409B2 3-Hydroxy-3-(2-thienyl) propionamides and production method thereof, and production method of 3-amino-1-(2-thienyl)-1-propanols using the same 失效
标题翻译： 3-羟基-3-（2-噻吩基）丙酰胺及其制备方法和使用其的3-氨基-1-（2-噻吩基）-1-丙醇的制备方法
公开(公告)号：US07659409B2
公开(公告)日：2010-02-09
申请号：US10944055
申请日：2004-09-20
申请人： Jun Takehara , Jingping Qu , Kazuaki Kanno , Hiroshi Kawabata , Yasumasa Dekishima , Makoto Ueda , Kyoko Endo , Takeshi Murakami , Tomoko Sasaki , Hisatoshi Uehara , Youichi Matsumoto , Shihomi Suzuki
发明人： Jun Takehara , Jingping Qu , Kazuaki Kanno , Hiroshi Kawabata , Yasumasa Dekishima , Makoto Ueda , Kyoko Endo , Takeshi Murakami , Tomoko Sasaki , Hisatoshi Uehara , Youichi Matsumoto , Shihomi Suzuki
IPC分类号： C07D333/22
CPC分类号： C07D333/16 , B01J31/1805 , B01J31/2295 , B01J2231/643 , B01J2531/80 , B01J2531/821
摘要： The object of the present invention is to provide 3-hydroxy-3-(2-thienyl)propionamides useful as synthesis intermediates of pharmaceutical preparations and the like and a method for obtaining optically active 3-amino-1-(2-thienyl)-1-propanols using the same with high reaction yield, high optical yield and industrially low cost.According to the present invention, 3-amino-1-(2-thienyl)-1-propanols are obtained by carrying out asymmetric reduction of a β-ketocarbonyl compound having thiophene ring in the presence of a catalyst constituted from a compound of a group VIII or IX metal in the periodic table (e.g., a ruthenium compound) and an asymmetric ligand represented by a specified optically active diamine derivative (e.g., a diphenylethylenediamine derivative), or using a cell, a treated product of said cell or the like of a microorganism, and as occasion demands, carrying out amidation of the ester group and then carrying out reduction of the amido group. (each of the substituents is as described in claim 1).
摘要翻译：本发明的目的是提供可用作药物制剂等的合成中间体的3-羟基-3-（2-噻吩基）丙酰胺和获得光学活性3-氨基-1-（2-噻吩基）使用相同的1-丙醇，反应产率高，光学收率高，工业成本低。根据本发明，3-氨基-1-（2-噻吩基）-1-丙醇通过在由组合的化合物构成的催化剂存在下进行具有噻吩环的β-酮羰基化合物的不对称还原而得到 VIII或IX族金属（例如钌化合物）和由特定光学活性二胺衍生物（例如二苯基乙二胺衍生物）表示的不对称配体，或使用电池，所述电池等的处理产物微生物，根据需要，进行酯基的酰胺化，然后进行酰胺基的还原。（每个取代基如权利要求1所述）。

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