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31. 发明申请

US20090186826A1 Cosmetic or dermopharmaceutical compositions of ceramides and polypeptides 审中-公开
标题翻译：神经酰胺和多肽的化妆品或皮肤药物组合物
公开(公告)号：US20090186826A1
公开(公告)日：2009-07-23
申请号：US12290142
申请日：2008-10-28
申请人： Karl Lintner , Denise E. Gabriele
发明人： Karl Lintner , Denise E. Gabriele
IPC分类号： A61K8/68 , A61Q19/08
CPC分类号： A61K8/64 , A61K8/68 , A61Q1/02 , A61Q19/00 , A61Q19/08
摘要： Personal care products including cosmetics, grooming products and topical pharmaceutical products can be produced including a polypeptide of between 3 and 12 amino acids in length and a ceramide. These formulations are particularly useful in addressing wrinkles in human subjects and in particular facial skin and hands. Certain analogs and derivatives of these polypeptides may be used in these formulations and/or alone. Methods of using these formulations are also disclosed.
摘要翻译：可以制备包括化妆品，美容产品和局部药物产品在内的个人护理产品，包括长度为3至12个氨基酸的多肽和神经酰胺。这些制剂在解决人类受试者，特别是面部皮肤和手中的皱纹方面特别有用。这些多肽的某些类似物和衍生物可用于这些制剂和/或单独使用。还公开了使用这些制剂的方法。

32. 发明申请

US20080213198A1 Cosmetic or Dermopharmaceutical Composition Comprising at Least one Udp Glucuronosyl Transferase (Ugt) Enzymes Inducer 有权
标题翻译：包含至少一种Udp葡糖醛酸转移酶（Ugt）酶诱导剂的化妆品或皮肤药物组合物
公开(公告)号：US20080213198A1
公开(公告)日：2008-09-04
申请号：US11587533
申请日：2005-04-25
申请人： Karl Lintner , Claire Mas Chamberlin
发明人： Karl Lintner , Claire Mas Chamberlin
IPC分类号： A61K8/49 , A61K38/02 , A61K31/352 , A61K8/64 , A61K8/97 , A61P17/00 , A61Q5/00 , A61Q17/00 , A61Q19/00
CPC分类号： A61K8/361 , A61K8/362 , A61K8/37 , A61K8/39 , A61K8/42 , A61K8/498 , A61K8/64 , A61K8/731 , A61K8/8147 , A61K8/8152 , A61K8/97 , A61K2800/78 , A61Q1/02 , A61Q5/006 , A61Q5/02 , A61Q5/06 , A61Q5/12 , A61Q7/00 , A61Q11/00 , A61Q19/00 , A61Q19/002 , A61Q19/06 , A61Q19/08
摘要： The invention relates to topical use of at least one UGT inducer for the preparation of a cosmetic or dermopharmaceutical composition comprising a dermatologically acceptable carrier to protect and/or enhance the state of the skin and prevent and/or treat imperfections of the skin.
摘要翻译：本发明涉及至少一种UGT诱导剂的局部用途，用于制备化妆品或皮肤药物组合物，其包含皮肤病学上可接受的载体以保护和/或增强皮肤的状态并预防和/或治疗皮肤的缺陷。

33. 发明申请

US20060110343A1 Cosmetic or dermopharmaceutical compositions comprising tyramine derivatives, method for preparing same, and use thereof 审中-公开
标题翻译：包含酪胺衍生物的化妆品或皮肤药物组合物，其制备方法及其用途
公开(公告)号：US20060110343A1
公开(公告)日：2006-05-25
申请号：US10519118
申请日：2003-06-25
申请人： Karl Lintner
发明人： Karl Lintner
IPC分类号： A61K8/42 , A61K8/46
CPC分类号： A61Q19/02 , A61K8/41 , C07C233/18 , C07C275/24 , C07C311/17
摘要： The invention concerns cosmetic or dermopharmaceutical compositions comprising tyramine derivatives and their salts. The invention also concerns the method for preparing same and use thereof for reducing pigmaentation.
摘要翻译：本发明涉及包含酪胺衍生物及其盐的化妆品或皮肤药物组合物。本发明还涉及其制备方法及其用于减少猪瘟的方法。

34. 发明公开

US20240010677A1 COSMETIC TETRAPEPTIDE, COMPOSITION AND USE 审中-公开
公开(公告)号：US20240010677A1
公开(公告)日：2024-01-11
申请号：US18035855
申请日：2021-11-15
申请人： Sederma
发明人： Philippe Mondon , Olivier Peschard , Richard Leroux
IPC分类号： C07K5/103 , A61K8/64 , A61Q19/00 , A61Q19/08 , A61Q7/00 , A61P17/14 , A61K8/73 , A61K8/9789 , A61K8/60 , A61K8/49
CPC分类号： C07K5/101 , A61K8/64 , A61Q19/00 , A61Q19/08 , A61Q7/00 , A61P17/14 , A61K8/735 , A61K8/9789 , A61K8/602 , A61K8/498 , A61K8/4913 , A61K38/00
摘要： The tetrapeptide has the general Formula X-LLAN-Z wherein at the N-terminal end X is selected from H, —CO—R1, —SO2—R1 or a biotinoyl group, at the C-terminal end Z is selected from OH, OR1, NH2, NHR1 or NR1R2, and R1 and R2 are selected from an alkyle, aryle, aralkyle, alkylaryl, alkoxy, saccharide and aryloxy, said group having from 1 to 24 carbon atoms. A preferred peptide is the Pal-LLAN. This tetrapeptide can stimulate the synthesis of molecules constituting the dermal extracellular matrix, in particular collagen 1 and fibrilin 1, and can be used for a cosmetic treatment, in particular anti-aging, anti-wrinkle and fine lines, to improve the skin mechanical properties, firmness/tone/elasticity/flexibility, to increase skin density and volume, for a restructuring effect and/or to fight against stretch marks, and skin sagging. The peptide is also adapted to stimulate hair growth.

35. 发明授权

US11827660B2 Synthesis strategy for gap protecting group 有权
公开(公告)号：US11827660B2
公开(公告)日：2023-11-28
申请号：US17310186
申请日：2020-01-26
申请人： Sederma
发明人： Cole Seifert
IPC分类号： C07F9/30 , C07F9/32 , C07F9/36 , C07F9/53 , C07K1/02 , C07K1/06 , C07F9/28
CPC分类号： C07F9/28 , C07F9/304 , C07F9/3229 , C07F9/36 , C07F9/5325 , C07K1/02 , C07K1/062
摘要： The present invention relates to a novel synthesis method to form particular molecules. These molecules have multiple uses, most notably in the field of protecting groups used throughout organic and synthetic chemistry. The disclosed method is safer, more cost- and time-effective, and more amenable to large scale production than those currently known in the art. The protecting groups synthesized are useful in GAP peptide synthesis.

36. 发明授权

US11684559B2 Topical cosmetic treatment of skin and scalp and corresponding active ingredient based on an extract of 有权
公开(公告)号：US11684559B2
公开(公告)日：2023-06-27
申请号：US17496358
申请日：2021-10-07
申请人： Sederma
发明人： Olga Gracioso , Caroline Ringenbach , Thibault Marchand , Philippe Mondon , Nicolas Barriere
IPC分类号： A61K36/00 , A61K8/49 , A61Q19/00 , A61K8/9789 , A61Q5/00 , A61Q19/08
CPC分类号： A61K8/4973 , A61K8/9789 , A61Q5/006 , A61Q19/00 , A61Q19/08 , A61K2800/5922
摘要： The invention provides the use of at least one alkyl-phthalide or a plant extract comprising mainly said alkyl-phthalide for the topical cosmetic treatment of the skin and of the scalp, in particular an anti-dandruff treatment. According to the invention, a CO2 supercritical extract of Apium graveolens seeds consisting mainly of sedanenolide may be used.

37. 发明授权

US10159636B2 Cosmetic composition containing acetylated oligoglucuronans 有权
公开(公告)号：US10159636B2
公开(公告)日：2018-12-25
申请号：US14665821
申请日：2015-03-23
申请人： Sederma, S.A.S.
发明人： Arnaud Fournial , Claire-Marie Grizaud , Caroline Le Moigne , Philippe Mondon
IPC分类号： A61K8/73 , A61Q19/08 , C08B37/00 , A61K9/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61K8/02
摘要： The present invention relates to the field of cosmetic and dermopharmaceutical compositions. It concerns oligomer compounds of D-glucuronic acid or D-glucuronate with a β (1-4) sequence (or oligoglucuronans) containing a degree of acetylation specifically between 8.7±0.5 and 9.2±0.5% by weight of O—CO—CH3 group compared to the weight of glucuronic acid and with a degree of polymerisation (DP) of 18-19±2. The oligomer compounds according to the present invention are intended to stimulate the elasticity of the dermis and epidermis although they also act to increase dermo-epidermal cohesion in order to combat skin ageing, lines, wrinkles, visible and/or tactile skin discontinuities, loss of firmness, elasticity and tone and to combat skin tissue deformability. The invention also concerns a cosmetic composition containing at least one compound as recited according to the present invention.

38. 发明申请

US20180318204A1 NEW USE OF AN EXTRACT OF PLANT ORIGIN OF GLOBULARIA AND METHOD FOR OBTAINING SAID EXTRACT BY IN VITRO PLANT CULTURE 审中-公开
公开(公告)号：US20180318204A1
公开(公告)日：2018-11-08
申请号：US15934042
申请日：2018-03-23
申请人： Sederma
发明人： Arnaud Fournial , Claire-Marie Grizaud , Philippe Mondon , Caroline Le Moigne
IPC分类号： A61K8/97 , A61K36/185 , A61Q19/08 , A61Q19/00 , A61K8/99 , A61Q5/00 , A61Q7/00
摘要： The extract of plant origin is characterized in that it is obtained from a plant of the genus Globularia, preferably the species Globularia Cordifolia. The extract according to the invention can be obtained by in vitro plant culture of undifferentiated cells.It can be used as an active agent in a composition for preventing and/or treating skin aging by stimulating detoxification reactions and cellular regeneration thanks to a hormetic type response. With such a composition, improvement of the visual appearance of the skin, radiance and transparency of complexion is obtained for example.

39. 发明授权

US08846019B2 Use of protoberberines as an active substance regulating the pilosebaceous unit 有权
标题翻译：使用原花青素作为调节毛囊型单位的活性物质
公开(公告)号：US08846019B2
公开(公告)日：2014-09-30
申请号：US11991587
申请日：2006-09-06
申请人： Karl Lintner , Claire Mas Chamberlin
发明人： Karl Lintner , Claire Mas Chamberlin
IPC分类号： A61Q9/00 , A61K31/00 , A61K9/00 , A61Q5/00 , A61K8/41 , A61Q7/02
CPC分类号： A61K8/416 , A61Q7/02
摘要： The present invention relates to cosmetic use, by topic application on the skin of at least one protoberberine, with exception of berberine, or a vegetable extract containing it, as an active substance reducing activity of the pilosebaceous unit, preferably inhibiting activity of the pilosebaceous unit. In particular, the invention relates to cosmetic use of at least one protoberberine, with exception of berberine, or a vegetable extract containing it, as an agent reducing, preferably inhibiting the growth of hairs of the face and/or the body, and/or seborrheic activity of the sebaceous glands. The invention also relates to a cosmetic composition comprising in a dermatologically acceptable carrier, at least one protoberberine, with exception of berberine, or a vegetable extract containing protoberberines, as an active substance, which reduces, preferably inhibits the skin's pilosebaceous unit activity.
摘要翻译：本发明涉及化妆品用途，除了小檗碱以外的至少一种原小檗碱的皮肤上，或含有它的植物提取物的皮肤上，作为活性物质还原活性物质，优选抑制皮脂单位的活性。特别地，本发明涉及除了小檗碱以外的至少一种原花青素或含有它的植物提取物的化妆品用途，作为还原剂，优选抑制面部和/或身体毛发的生长，和/或皮脂腺脂溢性活动。本发明还涉及一种化妆品组合物，其包含皮肤病学可接受的载体，除了小檗碱之外的至少一种原小檗碱，或含有作为活性物质的原花青素的植物提取物，其优选抑制皮肤的皮脂腺单位活性。

40. 发明授权

US08697656B2 Compounds, in particular peptides, compositions comprising them and cosmetic and dermo-pharmaceutical uses 有权
标题翻译：化合物，特别是肽，包含它们的组合物和化妆品和皮肤 - 药物用途
公开(公告)号：US08697656B2
公开(公告)日：2014-04-15
申请号：US13144614
申请日：2010-01-15
申请人： Arnaud Fournial , Philippe Mondon , Olivier Peschard
发明人： Arnaud Fournial , Philippe Mondon , Olivier Peschard
IPC分类号： A61K38/06 , A61Q19/00 , C07K5/09 , A61Q19/08
CPC分类号： A61K38/06 , A61K8/64 , A61Q1/06 , A61Q5/006 , A61Q7/00 , A61Q19/00 , A61Q19/02 , A61Q19/06 , A61Q19/08 , C07K5/0815
摘要： The present invention concerns a peptide of following formula I: R being a side chain having at least one heteroatom selected from sulfur, nitrogen and oxygen in a carbonyl form (C═O); R1 being either H or a lipophilic chain; R2 being either OH or a lipophilic chain. More particularly the present invention concerns a cosmetic composition comprising a peptide as recited above and a physiologically acceptable medium. Results on the activity of the compounds are obtained and on the general state of the skin and its appendages, in particular via the stimulation of extracellular matrix components.
摘要翻译：本发明涉及下列式I的肽：R是具有至少一个选自硫，氮和氧的杂原子（C = O）的侧链; R1是H或亲脂链; R2是OH或亲脂链。更具体地说，本发明涉及包含上述肽和生理上可接受的介质的化妆品组合物。获得化合物活性的结果，以及皮肤及其附属物的一般状态，特别是通过刺激细胞外基质组分。

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