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31. 发明授权

US08896312B2 Compact cryogenic NMR sensor with integrated active cooling device 有权
标题翻译：紧凑型低温NMR传感器，集成主动冷却装置
公开(公告)号：US08896312B2
公开(公告)日：2014-11-25
申请号：US13409135
申请日：2012-03-01
申请人： Philippe Stauffenegger , Klemens Kessler , Marco Tomaselli , Sven Radke , Bernhard Felber
发明人： Philippe Stauffenegger , Klemens Kessler , Marco Tomaselli , Sven Radke , Bernhard Felber
IPC分类号： G01V3/00 , G01R33/34 , G01R33/565
CPC分类号： G01R33/3403 , G01R33/34023 , G01R33/56509
摘要： An NMR measuring system with an NMR probehead has at least one cooling device (5a, b) generating a vibration spectrum of individual selective frequencies. The cooling device is mechanically connected to a vibration absorber (9a, 9b) having an oscillating mass element (27), whose resonance frequency is adjusted to the vibration frequency of the cooling device and/or to one of its harmonics. The cooling device has a cooling head which is thermally connected to an NMR resonator of the probehead via a flexible mechanical element. A vacuum housing of the probehead is designed in two parts which are mechanically connected via at least one damping element (30a-d). The lower part and the upper part of the vacuum housing are additionally mechanically flexibly connected to each other in a vacuum-tight fashion via a corrugated bellows (8a, 8b). The system minimizes sidebands in NMR spectra.
摘要翻译：具有NMR探针头的NMR测量系统具有产生各个选择频率的振动谱的至少一个冷却装置（5a，b）。冷却装置机械地连接到具有振荡质量元件（27）的振动吸收器（9a，9b），其谐振频率被调节到冷却装置的振动频率和/或其谐波之一。冷却装置具有通过柔性机械元件与探针头的NMR谐振器热连接的冷却头。探头的真空壳体被设计成两部分，它们通过至少一个阻尼元件（30a-d）机械连接。真空壳体的下部和上部通过波纹波纹管（8a，8b）以真空密封的方式另外机械地灵活地彼此连接。该系统使NMR谱中的边带最小化。

32. 发明授权

US08712489B2 Method for manufacturing a magnet coil configuration using a slit band-shaped conductor 有权
标题翻译：使用狭缝带状导体制造磁体线圈构造的方法
公开(公告)号：US08712489B2
公开(公告)日：2014-04-29
申请号：US13602221
申请日：2012-09-03
申请人： Robert Schauwecker , Robert Herzog , Riccardo Tediosi , Matteo Alessandrini
发明人： Robert Schauwecker , Robert Herzog , Riccardo Tediosi , Matteo Alessandrini
IPC分类号： H01F6/00
CPC分类号： H01F6/06 , H01F41/048
摘要： A magnet coil configuration (20-24) is manufactured from a band-shaped conductor (1), which is slit in the longitudinal direction except for its two end areas (2, 3) such that the band-shaped conductor (1) has a first and a second half band (4, 5) and two end areas (2, 3) which connect these two half bands (4, 5) to form a closed loop. The two half-bands (4,5) of the slit band-shaped conductor (1) are initially wound onto two separate intermediate coils (14,15) and the final coil structure is subsequently wound by alternate extraction of the two half-bands (4,5) from the intermediate coils (14,15). A simple method is thereby proposed for winding a slit band-shaped conductor to form a magnet coil configuration which also generates strong magnetic fields.
摘要翻译：磁带线圈构造（20-24）由带状导体（1）制造，所述带状导体（1）除了其两个端部区域（2,3）之外沿纵向方向被切开，使得带状导体（1）具有连接这两个半带（4,5）的第一和第二半带（4,5）和两个端部区域（2,3），以形成闭环。狭缝带状导体（1）的两个半带（4,5）最初卷绕到两个分离的中间线圈（14,15）上，并且随后通过交替提取两个半带（4,5）从中间线圈（14,15）。因此，提出了一种用于缠绕狭缝带状导体以形成也产生强磁场的磁体线圈构造的简单方法。

33. 发明授权

US08299792B2 Device for monitoring a living object during a magnetic resonance experiment 有权
标题翻译：用于在磁共振实验期间监测活体的装置
公开(公告)号：US08299792B2
公开(公告)日：2012-10-30
申请号：US12659237
申请日：2010-03-02
申请人： Daniel Schmidig
发明人： Daniel Schmidig
IPC分类号： G01V3/00
CPC分类号： G01R33/288 , A61B2562/222 , G01R33/3685 , G01R33/5673
摘要： A device for monitoring a living object during a magnetic resonance (MRI) experiment in an MRI tomograph, wherein the device comprises one or more individual electrodes which are connected in an electrically conducting fashion to the living object to be examined, and are connected to a monitoring device via signal lines, wherein each signal line comprises individual parts that are electrically connected to each other via impedances. The eigenfrequencies of these parts are higher than the NMR measuring frequency, preferably more than twice as high, and the parts are electrically connected to each other via frequency-dependent impedances Zn. The electro-magnetic coupling from the RF antenna and the gradient coils to the signal lines can thereby also be minimized in a simple fashion.
摘要翻译：一种用于在MRI断层摄影机中的磁共振（MRI）实验期间监测活体的装置，其中所述装置包括以导电方式连接到待检查的生物体上的一个或多个单独的电极，并且连接到监控设备，其中每个信号线包括通过阻抗彼此电连接的各个部件。这些部件的本征频率高于NMR测量频率，优选高于两倍高，并且部件通过频率相关阻抗Zn彼此电连接。因此，从RF天线和梯度线圈到信号线的电磁耦合也可以以简单的方式被最小化。

34. 外观设计

USD624661S1 Holder for sample containers 有权
公开(公告)号：USD624661S1
公开(公告)日：2010-09-28
申请号：US29357900
申请日：2010-03-18
申请人： Kurt Himmelsbach , Bent Grossniklaus
设计人： Kurt Himmelsbach , Bent Grossniklaus

35. 发明授权

US07728707B2 Split-coil magnet arrangement with improved mechanical construction 有权
标题翻译：分体式磁体布置具有改进的机械结构
公开(公告)号：US07728707B2
公开(公告)日：2010-06-01
申请号：US11882151
申请日：2007-07-31
申请人： Raffaele Gilardi , Stefan Schneider , Robert Schauwecker , Pierre-Alain Bovier
发明人： Raffaele Gilardi , Stefan Schneider , Robert Schauwecker , Pierre-Alain Bovier
IPC分类号： H01F1/00 , H01F3/00 , H01F7/00 , H01F5/00 , H01F6/00 , G01V3/00
CPC分类号： G01R33/3815 , G01R33/288 , G01R33/3802 , G01R33/3806 , H01F6/06 , H01F7/202 , H01F27/306 , Y10S505/879
摘要： A magnet arrangement with a magnet coil system (M) with two coil systems (C, D) that are each arranged in a container (B1, B2) positioned around the z axis and that are axially mechanically separated by a split (G), wherein each coil system (C, D) comprises a first (C1, D1) and a second coil section system (C2, D2), wherein the first coil section systems (C1, D1) are exposed to attractive magnetic forces showing toward the split (G) (KC1, KD1) and the second coil section systems (C2, D2), to repulsive magnetic forces showing away from the split (G) (KC2, KD2), and containing in the split (G) at least one mechanical structure that withstands compressive loads (E1, E2) and that supports a part of the attractive magnetic forces (KC1, KD1), is characterized in that, in the split (G) within the dimensions of the containers (B1, B2), a mechanical structure (H1) is provided that mechanically withstands tensile loads in the z direction, supports a part of the repulsive magnetic forces in the axial direction (KC2, KD2), is connected to the containers (B1, B2) and holds them together. With the inventive magnet arrangement, the magnetic forces can be better controlled. At the same time, a low-cost, space and weight saving assembly can be implemented.
摘要翻译：一种具有带有两个线圈系统（C，D）的磁体线圈系统（M）的磁体装置，每个线圈系统（C）分别布置在围绕z轴定位的容器（B1，B2）中，其中每个线圈系统（C，D）包括第一（C1，D1）和第二线圈段系统（C2，D2），其中第一线圈段系统（C1，D1）（G）（KC1，KD1）和第二线圈段系统（C2，D2），分离（G）（KC2，KD2）表示的斥力磁力，并且在分割（G）中包含至少一个机械承受压缩载荷（E1，E2）并支撑一部分有吸引力的磁力（KC1，KD1）的结构的特征在于，在容器（B1，B2）的尺寸内的裂缝（G）中，提供机械结构（H1），其机械地承受在z方向上的拉伸载荷，支撑一部分排斥磁力 x线方向（KC2，KD2）连接到容器（B1，B2）并保持在一起。利用本发明的磁体布置，可以更好地控制磁力。同时，可以实现低成本，空间和重量的组装。

36. 发明授权

US07503181B2 Quench seal 有权
标题翻译：淬火密封
公开(公告)号：US07503181B2
公开(公告)日：2009-03-17
申请号：US11291990
申请日：2005-12-02
申请人： Beat Mraz , Urs Meier , Agnès Glémot , Dieter Vogel
发明人： Beat Mraz , Urs Meier , Agnès Glémot , Dieter Vogel
IPC分类号： F25B19/00
CPC分类号： H01F6/04 , F17C2270/0527 , F25D19/006 , G01R33/3804
摘要： A cryostat configuration comprising an outer shell and a cryocontainer (2) for cryogenic fluid installed therein, wherein the cryocontainer (2) is connected to the outer shell via at least two suspension tubes (16), and with a neck tube (1) whose upper warm end is connected to the outer shell and whose lower cold end is connected to the cryocontainer (2) and into which a cold head (3) of a multi-stage cryocooler is installed, wherein the outer shell, the cryocontainer (2), the suspension tubes (16) and the neck tube (1) delimit an evacuated space, and wherein the cryocontainer (2) is moreover surrounded by at least one radiation shield which is connected to the suspension tubes (16) and optionally to the neck tube (1) of the cryocontainer (2) in a thermally conducting fashion, is characterized by a seal which can be manually and/or automatically actuated to separate the cold end of the neck tube (1) from the cryocontainer (2) in such a manner that fluid flow between the cryocontainer (2) and the neck tube (1) is minimized or completely interrupted. A cryostat configuration of this type ensures safe installation and removal of a cold head (3) into and from a neck tube (1) of a helium container (2).
摘要翻译：一种低温恒温器配置，其包括外壳和用于安装在其中的低温流体的低温容器（2），其中所述低温容器（2）经由至少两个悬挂管（16）和颈管（1）连接到外壳，颈管上部暖端连接到外壳，其下冷端连接到低温容器（2），并安装有多级低温冷却器的冷头（3），其中外壳，低温容器（2）悬挂管（16）和颈管（1）限定了抽空空间，并且其中低温容器（2）还包括至少一个与悬挂管（16）相连并且可选地连接到颈部的辐射屏蔽低温容器（2）的管（1）以导热方式，其特征在于可以手动和/或自动致动的密封件，从而将颈管（1）的冷端与低温容器（2）分离流体在低温容器之间流动的方式 2）和颈管（1）最小化或完全中断。这种类型的低温恒温器配置确保将冷头（3）安装到氦容器（2）的颈管（1）中和从其中取出。

37. 发明授权

US07463033B2 NMR probe component with a gradient chip with a slot for insertion of a sample chip 有权
标题翻译： NMR探针组件，带有带插槽的样品芯片的梯度芯片
公开(公告)号：US07463033B2
公开(公告)日：2008-12-09
申请号：US11892316
申请日：2007-08-22
申请人： Charles Massin , Michael Fey , Schimun Denoth , Frank Vincent
发明人： Charles Massin , Michael Fey , Schimun Denoth , Frank Vincent
IPC分类号： G01V3/00
CPC分类号： G01R33/302 , G01R33/34092 , G01R33/341
摘要： A nuclear magnetic resonance (NMR) probe component, comprising a microfabricated planar gradient chip (1), with a substrate thickness dgc≦3 mm, carrying three micromachined planar partial gradient coils (10a-10f) on each of its two outer surfaces (12a, 13a), wherein the partial gradient coils (10a-10f) of the gradient chip (1) form a three-dimensional gradient system, wherein the gradient chip (1) has a central guiding and positioning slot (15) between the two outer surfaces (12a, 13a). The probe component also has a sample chip (2) for carrying an NMR sample at a sample location, with a microfabricated planar RF coil (21), wherein the sample chip (2) fits exactly in the guiding and positioning slot (15) such that in a measurement position, the sample location coincides with the center of the gradient system. The NMR probe component has improved spatial resolution and allows good alignment of the RF coil and the gradient system.
摘要翻译：一种核磁共振（NMR）探针组分，其包含微制造的平面梯度碎片（1），其基底厚度dgc <= 3mm，在其两个外表面的每一个上承载三个微加工平面部分梯度线圈（10a-10f）其中所述梯度芯片（1）的部分梯度线圈（10a-10f）形成三维梯度系统，其中所述梯度芯片（1）在所述梯度芯片（1）之间具有中心引导和定位槽（15）外表面（12a，13a）。探针组件还具有用于在样品位置携带NMR样品的样品芯片（2），其具有微制造的平面RF线圈（21），其中样品芯片（2）精确地配合在引导和定位槽（15）中，在测量位置，样本位置与梯度系统的中心重合。 NMR探针组件具有改进的空间分辨率，并且允许RF线圈和梯度系统的良好对准。

38. 发明申请

US20080129288A1 Method of 2D-NMR correlation spectroscopy with double quantum filtration followed by evolution of single quantum transitions 有权
公开(公告)号：US20080129288A1
公开(公告)日：2008-06-05
申请号：US11812820
申请日：2007-06-22
申请人： Narayanan Chandrakumar , Velusamy Ramesh
发明人： Narayanan Chandrakumar , Velusamy Ramesh
IPC分类号： G01R33/20
CPC分类号： G01R33/4633
摘要： A method of 2-dimensional nuclear magnetic resonance (2D-NMR) correlation spectroscopy, comprises a pulse sequence with the following steps: excitation of double quantum coherence; immediate reconversion to single transition single quantum coherence; evolution of the set of single transitions; mixing with zero quantum mixing Hamiltonian; and signal detection. The method can achieve an improved sensitivity, has a transition selectivity and suppresses diagonal peaks.

39. 发明申请

US20070227623A1 Method for producing a superconductive element 有权
标题翻译：超导元件的制造方法
公开(公告)号：US20070227623A1
公开(公告)日：2007-10-04
申请号：US11223039
申请日：2005-09-12
申请人： Rene Fluekiger , Vital Abaecherli , Daniel Eckert
发明人： Rene Fluekiger , Vital Abaecherli , Daniel Eckert
IPC分类号： H01L39/24
CPC分类号： H01L39/2409 , C22F1/08 , Y10T29/49014
摘要： A method for producing a superconductive element, in particular a multifilament wire, starting from a composite (1) comprising a bronze matrix containing Cu and Sn, in which at least one elongated structure containing Nb or an Nb alloy, in particular NbTa, is embedded, whereby in a first step the composite is extruded at a temperature between 300° C. and 750° C., followed by cold or hot working and annealing steps in which the composite is elongated in parallel to the elongated structure and softened by temperature treatment, followed by a stacking step, in which a multitude of elongated composites from the preceding cold or hot working steps are bundled, the steps of extruding, elongating, annealing and stacking being repeated one or more times, followed by a final elongating process, including intermediate annealing processes, in which the composite is elongated to its final length, the superconductive phase being obtained by a heat treatment including a solid state diffusion reaction is characterized in that at least part of the elongating steps and annealing steps are performed by isothermal hot rolling in a temperature region between 450° C. and 750° C. at or above recrystallization temperature of the bronze matrix.
摘要翻译：一种由包含Cu和Sn的青铜基体的复合材料（1）开始制造超导元件，特别是复丝的方法，其中至少包含Nb或Nb合金，特别是NbTa的细长结构被嵌入，其中在第一步骤中，复合材料在300℃和750℃之间的温度下挤出，随后冷或热加工和退火步骤，其中复合材料与细长结构平行延伸并通过温度处理软化然后进行堆叠步骤，其中将来自先前冷或热加工步骤的多个细长复合材料捆扎在一起，挤出，拉伸，退火和堆叠的步骤重复一次或多次，随后进行最终拉伸工艺，包括中间退火工艺，其中复合材料延伸到其最终长度，超导相通过包括固态扩散试验的热处理获得其特征在于，在青铜基体的重结晶温度以上或以上，在450℃〜750℃的温度范围内，通过等温热轧进行至少一部分延伸工序和退火工序。

40. 发明申请

US20070227622A1 Method for producing a superconductive element 有权
标题翻译：超导元件的制造方法
公开(公告)号：US20070227622A1
公开(公告)日：2007-10-04
申请号：US11223053
申请日：2005-09-12
申请人： Rene Fluekiger , Vital Abaecherli
发明人： Rene Fluekiger , Vital Abaecherli
IPC分类号： H01L39/24
CPC分类号： H01L39/2409 , Y10T29/49014
摘要： A method for producing a superconductive element, in particular a multifilament wire, starting from a composite (1) comprising a bronze matrix containing Cu and Sn, in which at least one elongated structure containing Nb or an Nb alloy, in particular NbTa, is embedded, whereby in a first step the composite is extruded at a temperature between 300° C. and 750° C., followed by cold or hot working and annealing steps in which the composite is elongated in parallel to the elongated structure and softened by a temperature treatment (=“intermediate annealing”), followed by a stacking step, in which a multitude of elongated composites from the preceding cold or hot working steps are bundled, the steps of extruding, elongating, annealing and stacking being repeated one or more times, followed by a final elongating process, including intermediate annealing processes, in which the composite is elongated to its final length, the superconductive phase being obtained by a heat treatment including a solid state diffusion reaction is characterized in that at least part of the elongating steps and annealing steps are performed by cold working preceded by an intermediate annealing between 520° C. and 750° C., i. e. above the normal Cu—Sn recrystallization temperature, and by a fast cooling within less than 30 s to 100° C. or below (=“Rapid Intermediate Quenching” [RIQ]).
摘要翻译：一种由包含Cu和Sn的青铜基体的复合材料（1）开始制造超导元件，特别是复丝的方法，其中至少包含Nb或Nb合金，特别是NbTa的细长结构被嵌入，其中在第一步骤中，将复合材料在300℃和750℃之间的温度下挤出，随后冷或热加工和退火步骤，其中复合材料与细长结构平行延伸并软化温度处理（=“中间退火”），然后进行堆叠步骤，其中将来自先前冷或热加工步骤的多个细长复合材料捆扎在一起，挤出，拉伸，退火和堆叠的步骤重复一次或多次，然后进行最终拉伸工艺，包括中间退火工艺，其中复合材料延伸到其最终长度，超导相通过热处理获得，包括固态扩散反应的特征在于，至少部分拉伸步骤和退火步骤通过在520℃和750℃之间的中间退火之前的冷加工进行， e。高于正常Cu-Sn重结晶温度，并在低于30秒至100℃或更低温度（=“快速中间淬火”[RIQ]）内的快速冷却。

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