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21. 发明授权

US5166431A Preparation of alkanesulfonamides 失效
标题翻译：烷基磺酰胺的制备
公开(公告)号：US5166431A
公开(公告)日：1992-11-24
申请号：US718136
申请日：1991-06-20
申请人： Stanley R. Sandler , James S. Perilli , John F. Kennoy
发明人： Stanley R. Sandler , James S. Perilli , John F. Kennoy
IPC分类号： C07C303/38 , C07C311/03
CPC分类号： C07C303/38
摘要： A method for the preparation of alkanesulfonamides in high purity and high yield using solvents selected from C.sub.3 to C.sub.8 cyclic ethers or mixtures thereof is disclosed. The final products have use as synthetic intermediates for the manufacture of useful final products.
摘要翻译：公开了使用选自C3至C8环醚或其混合物的溶剂制备高纯度和高收率的烷烃磺酰胺的方法。最终产品用作制造有用的最终产品的合成中间体。

22. 发明授权

US5103010A Diphenylethylene derivatives, pharmaceutical compositions containing same and treatment method 失效
标题翻译：二氯乙烯衍生物，含有该药物的药物组合物和治疗方法
公开(公告)号：US5103010A
公开(公告)日：1992-04-07
申请号：US612829
申请日：1990-11-13
申请人： Youji Yamagishi , Kozo Akasaka , Takeshi Suzuki , Mitsuaki Miyamoto , Kouji Nakamoto , Kazuo Okano , Shinya Abe , Hironori Ikuta , Kenji Hayashi , Hiroyuki Yoshimura , Tohru Fujimori , Koukichi Harada , Isao Yamatsu
发明人： Youji Yamagishi , Kozo Akasaka , Takeshi Suzuki , Mitsuaki Miyamoto , Kouji Nakamoto , Kazuo Okano , Shinya Abe , Hironori Ikuta , Kenji Hayashi , Hiroyuki Yoshimura , Tohru Fujimori , Koukichi Harada , Isao Yamatsu
IPC分类号： C07C57/42 , A61K31/15 , A61K31/165 , A61K31/18 , A61K31/19 , A61K31/215 , A61K31/22 , A61K31/275 , A61K31/277 , A61K31/33 , A61P7/02 , A61P9/08 , A61P9/10 , C07C51/00 , C07C59/64 , C07C67/00 , C07C69/618 , C07C231/00 , C07C231/02 , C07C233/01 , C07C233/02 , C07C233/11 , C07C235/14 , C07C235/34 , C07C237/20 , C07C239/00 , C07C241/00 , C07C251/40 , C07C251/60 , C07C253/00 , C07C253/30 , C07C255/04 , C07C255/32 , C07C255/34 , C07C255/37 , C07C255/41 , C07C255/61 , C07C255/62 , C07C257/04 , C07C257/06 , C07C257/10 , C07C257/18 , C07C301/00 , C07C303/38 , C07C311/00 , C07C311/13 , C07C311/15 , C07C311/17 , C07C325/00 , C07C327/00 , C07C327/58 , C07D207/46 , C07D213/40 , C07D213/72 , C07D213/75 , C07D249/12 , C07D257/04 , C07D339/08 , C07D521/00
CPC分类号： C07D257/04 , C07C235/14 , C07C235/34 , C07C251/40 , C07C251/60 , C07C255/00 , C07C255/41 , C07C255/62 , C07C257/06 , C07C257/18 , C07C311/13 , C07C311/17 , C07C327/58 , C07C59/64 , C07D207/46 , C07D213/40 , C07D213/75 , C07D231/12 , C07D233/56 , C07D249/08 , C07D339/08
摘要： A new diphenyl-methane derivative is useful to inhibit agglomeration of blood and is defined by the formula, including a diphenylethylene derivative and a benzophenone oxime ether derivative. ##STR1## in which R1 and R2 each are hydrogen, hydroxyl or a lower alkoxy, U is .dbd.CXY or .dbd.N--O--W,X is hydrogen, cyano or --COR6, R6 being hydroxyl or an amino, Y is --R10--COOR3, R3 being hydrogen or a lower alkoxy, R10 being an alkylene having 1 to 3 carbon atoms, straight or branched, --CO--NR4R5, R4 and R5 each being hydrogen, a lower alkyl or a lower arylalkyl, --CH2--NHSO2--C6H5 or --C(R8).dbd.NR7, R7 being a lower alkoxy or an aryl, R8 is --VR9, V being oxygen, sulfur or nitrogen, R9 being an alkyl or an aryl,W is --CH2--CO--CH2--COOR13, R13 being hydrogen or a lower alkyl, --CH2--C(.dbd.NOR14)--CH2--COOR15, R15 being hydrogen or a lower alkyl, R14 being a lower alkyl, --CH(CN)--(CH2)q--COOR16, R16 being hydrogen or a lower alkyl, q being an integer of 1 to 3, or --(CH2)p--Z, Z being --SH, --SCN or a monovalent group derived from a five- or six-membered ring which may be substituted by a ring having one or more sulfur atoms in the ring, p being 1 or 2.
摘要翻译：二苯基甲烷衍生物。式（I）为新的（其中R 1和R 2各自为H，OH或低级烷氧基; U = -C XY或= NOW; X = H，CN或-COR 6; R 6 = OH或NH 2; Y = COOR 3，-CONR 4 R 5，-CH 2 NHSO 2 -C 6 H 5或-C（R 8）= NR 7; R 3 = H或低级烷氧基; R 10 =支链1-3C亚烷基; R 4和R 5各自为H，低级烷基或低级芳基烷基; 低级烷氧基或芳基; R8 = -VR9; V = O，S或N; R9 =烷基或芳基; W = -CH2-CO-CH2-COOR13，-CH2-C（= NOR14）-CH2-COOR15，-CH （CN） - （CH 2）q -COOR 16或 - （CH 2）pZ; R 13 = H或低级烷基; R 14 =低级烷基; R 15 = H或低级烷基; R 16 = H或低级烷基; q = = -SH，-SCN或衍生自5-或6-元环选择的单价gp，通过环中具有1个或更多个S的环; p = 1或2。

23. 发明授权

US5072040A Process for synthesis of sulfonylimides 失效
标题翻译：磺酰亚胺的合成方法
公开(公告)号：US5072040A
公开(公告)日：1991-12-10
申请号：US613642
申请日：1990-12-03
申请人： Michel Armand
发明人： Michel Armand
IPC分类号： C07C303/38 , C07C311/48 , C08K5/43 , C08L71/02 , H01M4/60 , H01M6/16 , H01M6/18
CPC分类号： C07C303/38 , H01M6/166 , H01M6/181
摘要： The invention relates to a process for the synthesis of sulfonylimides.The process for the synthesis of sulfonylimides of the general formula M[RSO.sub.2).sub.2 N].sub.y, in which M represents a metal chosen from alkali metals, alkaline earth metals, rare earths, Al, Sc, Y and Th, R represents a monovalent radical chosen from linear or branched aliphatic radicals having 1 to 8 carbon atoms, alicyclic radicals having 3 to 8 carbon atoms, aryl radicals having 3 to 8 carbon atoms, and y is a number equal to the valence of M, is characterized in that an ionic nitride of the formula M.sub.3 N.sub.y, in which M and y have the meaning given above, is reacted with a sulfonyl halide of the formula RSO.sub.2 X, in which R has the meaning given above, and X is chosen from F or Cl, in an aprotic polar solvent.
摘要翻译： PCT No.PCT / FR90 / 00240 Sec。 371日期1990年12月3日第 102（e）日期1990年12月3日PCT 1990年4月5日提交PCT公布。 WO90 / 11999 PCT出版物 1990年10月18日的日期。本发明涉及磺酰亚胺的合成方法。合成通式M [RSO 2] 2 N] y的磺酰亚胺的方法，其中M表示选自碱金属，碱土金属，稀土，Al，Sc，Y和Th的金属，R表示一价基团选自具有1至8个碳原子的直链或支链脂族基团，具有3至8个碳原子的脂环族基团，具有3至8个碳原子的芳基，y是等于M的化合价的数，其特征在于离子其中M和y具有上述含义的式M3Ny的氮化物与式RSO2X的磺酰卤反应，其中R具有上述含义，X选自F或Cl，非质子极性溶剂。

24. 发明授权

US5034417A New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same 失效
标题翻译：新的烷基磺酰苯胺衍生物，其制备方法和包含其的药物组合物
公开(公告)号：US5034417A
公开(公告)日：1991-07-23
申请号：US197966
申请日：1988-05-24
申请人： Masaaki Matsuo , Kiyoshi Tsuji , Nobukiyo Konishi , Hiroyuki Okumura
发明人： Masaaki Matsuo , Kiyoshi Tsuji , Nobukiyo Konishi , Hiroyuki Okumura
IPC分类号： C07D317/16 , A61K31/18 , A61K31/19 , A61K31/275 , A61K31/325 , A61K31/33 , A61K31/41 , A61K31/415 , A61K31/4184 , A61K31/425 , A61K31/426 , A61K31/44 , A61K31/4402 , A61K31/47 , A61K31/496 , A61K31/505 , A61P25/04 , A61P29/00 , C07C67/00 , C07C303/38 , C07C311/08 , C07C313/00 , C07C315/04 , C07C317/32 , C07C317/34 , C07C317/36 , C07C317/48 , C07C319/20 , C07C323/37 , C07C323/49 , C07C323/62 , C07C323/65 , C07D213/20 , C07D213/28 , C07D213/50 , C07D213/70 , C07D215/36 , C07D235/28 , C07D249/12 , C07D257/04 , C07D271/06 , C07D271/07 , C07D277/20 , C07D277/36 , C07D277/40 , C07D277/46 , C07D277/52 , C07D295/192 , C07D333/34 , C07D487/04 , C07D521/00
CPC分类号： C07D213/20 , C07C317/32 , C07C323/37 , C07D213/70 , C07D215/36 , C07D235/28 , C07D249/12 , C07D257/04 , C07D271/07 , C07D277/36 , C07D277/40 , C07D277/46 , C07D295/192 , C07D333/34 , C07D487/04
摘要： This invention relates to new alkanesulfonanilide derivatives and pharmaceutically acceptable salts thereof which have inflammatory activities and analgesic activities, to pharmaceutical compositions containing the same and to a method for the treatment of inflammatory disease or pains in human beings and animals.

25. 发明授权

US4996360A Preparation of arylsulfonyl (alkyl) amides 失效
标题翻译：芳基磺酰基（烷基）酰胺的制备
公开(公告)号：US4996360A
公开(公告)日：1991-02-26
申请号：US323857
申请日：1989-03-15
申请人： Raymond Commandeur , Elie Ghenassia
发明人： Raymond Commandeur , Elie Ghenassia
IPC分类号： C07C303/38 , C07C311/16
CPC分类号： C07C303/38
摘要： The arylsulfonyl(alkyl)amides, notably N-(n-butyl)benzenesulfonamide, well adopted as heat-stable plasticizers for polyamides, e.g., nylon 11 and nylon 12, are directly prepared by (a) intimately contacting an arylsulfonyl halide with a stoichiometric excess of both an alkylamine and an alkaline agent, with the alkaline agent being present in aqueous solution, (b) eliminating water and excess alkylamine from the organic phase produced in stage (a), and (c) separating final product arylsulfonyl(alkyl)amide from the residual organic phase remaining after stage (b).
摘要翻译：芳基磺酰基（烷基）酰胺，特别是N-（正丁基）苯磺酰胺，被广泛用作聚酰胺例如尼龙11和尼龙12的热稳定增塑剂，直接通过以下方法制备：（a）使芳基磺酰卤与化学计量碱性试剂存在于水溶液中，（b）从阶段（a）中产生的有机相中除去水和过量的烷基胺，和（c）分离最终产物芳基磺酰基（烷基）（b）后剩余有机相的酰胺。

26. 发明授权

US4978767A Diphenylethylene derivative and pharmaceutical use 失效
标题翻译：二苯乙烯衍生物和药用
公开(公告)号：US4978767A
公开(公告)日：1990-12-18
申请号：US364710
申请日：1989-06-09
申请人： Youji Yamagishi , Kozo Akasaka , Takeshi Suzuki , Mitsuaki Miyamoto , Kouji Nakamoto , Kazuo Okano , Shinya Abe , Hironori Ikuta , Kenji Hayashi , Hiroyuki Yoshimura , Tohru Fujimori , Koukichi Harada , Isao Yamatsu
发明人： Youji Yamagishi , Kozo Akasaka , Takeshi Suzuki , Mitsuaki Miyamoto , Kouji Nakamoto , Kazuo Okano , Shinya Abe , Hironori Ikuta , Kenji Hayashi , Hiroyuki Yoshimura , Tohru Fujimori , Koukichi Harada , Isao Yamatsu
IPC分类号： C07C57/42 , A61K31/15 , A61K31/165 , A61K31/18 , A61K31/19 , A61K31/215 , A61K31/22 , A61K31/275 , A61K31/277 , A61K31/33 , A61P7/02 , A61P9/08 , A61P9/10 , C07C51/00 , C07C59/64 , C07C67/00 , C07C69/618 , C07C231/00 , C07C231/02 , C07C233/01 , C07C233/02 , C07C233/11 , C07C235/14 , C07C235/34 , C07C237/20 , C07C239/00 , C07C241/00 , C07C251/40 , C07C251/60 , C07C253/00 , C07C253/30 , C07C255/04 , C07C255/32 , C07C255/34 , C07C255/37 , C07C255/41 , C07C255/61 , C07C255/62 , C07C257/04 , C07C257/06 , C07C257/10 , C07C257/18 , C07C301/00 , C07C303/38 , C07C311/00 , C07C311/13 , C07C311/15 , C07C311/17 , C07C325/00 , C07C327/00 , C07C327/58 , C07D207/46 , C07D213/40 , C07D213/72 , C07D213/75 , C07D249/12 , C07D257/04 , C07D339/08 , C07D521/00
CPC分类号： C07D257/04 , C07C235/14 , C07C235/34 , C07C251/40 , C07C251/60 , C07C255/00 , C07C255/41 , C07C255/62 , C07C257/06 , C07C257/18 , C07C311/13 , C07C311/17 , C07C327/58 , C07C59/64 , C07D207/46 , C07D213/40 , C07D213/75 , C07D231/12 , C07D233/56 , C07D249/08 , C07D339/08
摘要： A new diphenyl-methane derivative is useful to inhibit agglomeration of blood and is defined by the formula, including a diphenylethylene derivative and a benzophenone oxime ether derivative. ##STR1## in which R1 and R2 each are hydrogen, hydroxyl or a lower alkoxy, U is .dbd.CXY or .dbd.N--O--W,X is hydrogen, cyano or --COR6, R6 being hydroxyl or an amino, Y is --R10--COOR3, R3 being hydrogen or a lower alkoxy, R10 being an alkylene having 1 to 3 carbon atoms, straight or branched, --CO--NR4R5, R4 and R5 each being hydrogen, a lower alkyl or a lower arylalkyl, --CH2--NHSO2--C6H5 or --C(R8).dbd.NR7, R7 being a lower alkoxy or an aryl, R8 is --VR9, V being oxygen, sulfur or nitrogen, R9 being an alkyl or an aryl,W is --CH2--CO--CH2--COOR13, R13 being hydrogen or a lower alkyl, --CH2--C(.dbd.NOR14)--CH2--COOR15, R15 being hydrogen or a lower alkyl, R14 being a lower alkyl, --CH(CN)--(CH2)q--COOR16, R16 being hydrogen or a lower alkyl, q being an integer of 1 to 3, or --(CH2)p--Z, Z being --SH, --SCN or a monovalent group derived from a five- or six-membered ring which may be substituted by a ring having one or more sulfur atoms in the ring, p being 1 or 2.
摘要翻译：二苯基甲烷衍生物。式（I）为新的（其中R 1和R 2各自为H，OH或低级烷氧基; U = -C XY或= NOW; X = H，CN或-COR 6; R 6 = OH或NH 2; Y = COOR 3，-CONR 4 R 5，-CH 2 NHSO 2 -C 6 H 5或-C（R 8）= NR 7; R 3 = H或低级烷氧基; R 10 =支链1-3C亚烷基; R 4和R 5各自为H，低级烷基或低级芳基烷基; 低级烷氧基或芳基; R8 = -VR9; V = O，S或N; R9 =烷基或芳基; W = -CH2-CO-CH2-COOR13，-CH2-C（= NOR14）-CH2-COOR15，-CH （CN） - （CH 2）q -COOR 16或 - （CH 2）pZ; R 13 = H或低级烷基; R 14 =低级烷基; R 15 = H或低级烷基; R 16 = H或低级烷基; q = = -SH，-SCN或衍生自5-或6-元环选择的单价gp，通过环中具有1个或更多个S的环; p = 1或2。

27. 发明授权

US4680395A Sulfonylisoureas 失效
公开(公告)号：US4680395A
公开(公告)日：1987-07-14
申请号：US707325
申请日：1985-03-01
申请人： Haukur Kristinsson , Werner Topfl
发明人： Haukur Kristinsson , Werner Topfl
IPC分类号： C07D251/46 , A01N47/36 , A01N47/42 , C07C67/00 , C07C301/00 , C07C303/38 , C07C303/40 , C07C311/63 , C07D239/42 , C07D239/47 , C07D251/16 , C07D521/00 , C07D239/69
CPC分类号： C07D521/00
摘要： Pyrimidyl-sulfonyl isoureas of the formula ##STR1## in which R.sub.a is the difluoromethoxy group,R.sub.b is hydrogen, halogen, C.sub.1 -C.sub.5 -alkyl, C.sub.1 l-C.sub.5 -haloalkyl, C.sub.1 -C.sub.5 -alkoxy, C.sub.1 -C.sub.5 -haloalkoxy, C.sub.1 -C.sub.5 -alkylthio, C.sub.2 -C.sub.10 -alkoxyalkyl or C.sub.2 -C.sub.10 -alkoxyalkoxy or is an amino group ##STR2## wherein R.sub.c is hydrogen, methyl or ethyl, andR.sub.d is hydrogen, methyl, ethyl or methoxy,A is a radical of the formula ##STR3## Y is oxygen, sulfur or ##STR4## R.sub.1 is hydrogen, halogen, nitro, trifluoromethyl, C.sub.1 -C.sub.5 -alkyl, C.sub.1 -C.sub.5 -alkoxy, --COR.sub.7, --S(O).sub.m --C.sub.1 -C.sub.5 -alkyl, --SO.sub.2 R.sub.10, XR.sub.11 or --OSO.sub.2 C.sub.1 -C.sub.5 -alkyl,R.sub.2 is hydrogen, fluorine, chlorine, bromine, nitro, C.sub.1 -C.sub.5 -alkyl, C.sub.1 -C.sub.5 -alkoxy, trifluoromethyl, C.sub.1 -C.sub.5 -haloalkoxy or --COR.sub.7,R.sub.3 is hydrogen, fluorine, chlorine, bromine, nitro, methoxy or trifluoromethyl,R.sub.4 is hydrogen, halogen, nitro, C.sub.1 -C.sub.5 -alkyl, methoxy, --COR.sub.7 or --SO.sub.2 NR.sub.8 R.sub.9,R.sub.5 is hydrogen, fluorine, chlorine, bromine, nitro, C.sub.1 -C.sub.5 -alkyl, C.sub.1 -C.sub.5 -alkoxy, trifluoromethyl, --S(O).sub.m C.sub.1 -C.sub.5 -alkyl, --COR.sub.7 or --SO.sub.2 NR.sub.8 R.sub.9,R.sub.6 is hydrogen, fluorine, methyl or methoxy,R.sub.7 is hydrogen, C.sub.1 -C.sub.5 -alkyl, C.sub.1 -C.sub.5 -haloalkyl, C.sub.1 -C.sub.5 -alkoxy, C.sub.1 -C.sub.5 -haloalkoxy, C.sub.2 l-C.sub.10 -alkoxyalkoxy, C.sub.3 -C.sub.5 -alkenyloxy, C.sub.3 -C.sub.5 -alkynyloxy, phenoxy, benzyloxy, C.sub.1 -C.sub.5 -alkylthio or --NR.sub.8 R.sub.9,R.sub.8 is hydrogen, C.sub.1 -C.sub.5 -alkyl, cyanoalkyl having a maximum of 5 carbon atoms, methoxy, ethoxy or C.sub.3 -C.sub.5 -alkenyl,R.sub.9 is hydrogen, C.sub.1 -C.sub.5 -alkyl or C.sub.3 -C.sub.5 -alkenyl, orR.sub.8 and R.sub.9 together with the nitrogen atom binding them form a 5- or 6-membered, saturated heterocycle which can contain an oxygen or sulfur atom as ring member,R.sub.10 is C.sub.1 -C.sub.5 -haloalkoxy or --NR.sub.8 R.sub.9,R.sub.11 is C.sub.1 -C.sub.5 -alkyl which is substituted by halogen, C.sub.1 -C.sub.5 -alkoxy, --S(O).sub.m C.sub.1 -C.sub.5 -alkyl, --S(O).sub.m C.sub.1 -C.sub.5 -haloalkyl or C.sub.2 l-C.sub.5 -alkenyl which is unsubstituted or substituted by halogen or C.sub.1 -C.sub.5 -alkoxy,R.sub.x is C.sub.1 -C.sub.5 -alkyl,X is oxygen or --X(O).sub.m -- andm is zero, one or twoare intermediates for the preparation of pyrimidyl-sulfonyl ureas having useful herbicidyl and growth regulating properties.

28. 发明授权

US4569801A Alkylsulfonamidophenylalkylamines 失效
标题翻译：烷基磺酰胺基苯基烷基胺
公开(公告)号：US4569801A
公开(公告)日：1986-02-11
申请号：US660816
申请日：1984-10-15
申请人： Bryan B. Molloy , Mitchell I. Steinberg
发明人： Bryan B. Molloy , Mitchell I. Steinberg
IPC分类号： A61K31/18 , A61P9/06 , C07C67/00 , C07C301/00 , C07C303/38 , C07C311/02 , C07C311/08 , C07C143/75
CPC分类号： A61K31/18 , C07C311/02
摘要： The present invention relates to a new class of alkylsulfonamidophenylalkylamines which are potent antiarrhythmic agents having good oral bioavailability properties.
摘要翻译：本发明涉及一类新的烷基磺酰胺基苯基烷基胺，它们是具有良好的口服生物利用度性质的有效的抗心律失常药。

29. 发明授权

US4537896A Thrombin inhibiting arylsulfonyl guanidinophenylalanine amides 失效
标题翻译：凝血酶抑制芳基磺酰胍胍苯丙氨酸酰胺
公开(公告)号：US4537896A
公开(公告)日：1985-08-27
申请号：US504338
申请日：1983-06-14
申请人： Carl G. Claeson , Stig I. Gustavsson
发明人： Carl G. Claeson , Stig I. Gustavsson
IPC分类号： A61K31/18 , A61K31/445 , A61P7/02 , C07C67/00 , C07C301/00 , C07C303/38 , C07C311/18 , C07C311/42 , C07D211/14 , C07D295/185 , G01N33/86 , A61K31/16 , C07C147/13 , C07D211/16
CPC分类号： C07D295/185 , C07C311/42
摘要： New thrombin inhibiting N.sup..alpha. -arylsulfonyl-p-guanidinophenylalanine amides of the formula ##STR1## wherein Ar is a substituted aryl and R.sub.1 and R.sub.2 are an alkyl group having 1-5 carbon atoms or together with the amine nitrogen form an heterocyclic ring, in racemate form as well as in form of optical active antipodes, theirs pharmaceutically acceptable salts, methods for their preparation, pharmaceutical composition and diagnostical preparation containing these compounds, use of the compounds in treatments of thrombosis and methods of treatment of thrombosis as well as methods for determination of thrombin concentration in blood.
摘要翻译：新型凝血酶抑制式为“IMAGE”的Nα - 芳基磺酰基 - 对胍胍苯丙氨酸酰胺，其中Ar为取代的芳基，R 1和R 2为具有1-5个碳原子的烷基或与胺氮一起形成杂环，外消旋形式以及光学活性对映体的形式，它们的药学上可接受的盐，其制备方法，含有这些化合物的药物组合物和诊断制剂，治疗血栓形成的用途以及血栓形成治疗方法测定血液中凝血酶浓度。

30. 发明授权

US4499303A Antihyperlipidemic N-benzoylsulfamates, N-benzylsulfamates and benzylsulfonamides 失效
标题翻译：抗高脂血症N-苯甲酰基磺酰胺，N-苄基磺酰胺和苄基磺酰胺
公开(公告)号：US4499303A
公开(公告)日：1985-02-12
申请号：US536218
申请日：1983-09-27
申请人： Steven D. Wyrick , Iris H. Hall , Agnes Dubey
发明人： Steven D. Wyrick , Iris H. Hall , Agnes Dubey
IPC分类号： A61K31/165 , A61P3/06 , C07C67/00 , C07C301/00 , C07C303/34 , C07C303/38 , C07C307/02 , C07C311/13 , C07C143/74 , C07C143/78
CPC分类号： C07C307/02
摘要： This invention relates to novel N-benzoylsulfamates, N-benzylsulfamates and benzylsulfonamides and pharmacologically acceptable salts thereof, a method for lowering serum levels in mammals by administration of said compounds, and pharmaceutical compositions thereof.
摘要翻译：本发明涉及新的N-苯甲酰基磺酰胺，N-苄基磺酸酯和苄基磺酰胺及其药理学上可接受的盐，通过施用所述化合物降低哺乳动物血清水平的方法及其药物组合物。

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