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21. 发明授权

US06577891B1 IR spectroscopic endoscope with inflatable balloon 失效
标题翻译：红外光谱内窥镜带充气气球
公开(公告)号：US06577891B1
公开(公告)日：2003-06-10
申请号：US09466299
申请日：1999-12-17
申请人： Werner Jaross , Matthias Boese , Arno Simon
发明人： Werner Jaross , Matthias Boese , Arno Simon
IPC分类号： A61B600
CPC分类号： A61B1/00181 , A61B1/00082 , A61B1/00177 , A61B1/00183 , A61B1/0615 , A61B5/0075 , A61B5/0086
摘要： A device for the optical spectroscopic examination of interior surfaces (2, 2′) of a body, e.g. of blood vessels (1), comprising an optical spectrometer and an endoscope (3) with a light guide for illuminating the surfaces, wherein at the proximal end of the light guide it is supplied with light and at the distal of the light guide the light can be launched to the surfaces to be examined, wherein at the distal end of this endoscope there is provided a device for receiving the light reflected by the surfaces to be examined, is characterized in that the distal end of the light guide is arranged within an inflatable balloon (4) with an elastic exterior, and that the light decoupled from the light guide and the light reflected by the surfaces to be examined to the receiving device penetrates in each case the exterior of the balloon. In this way, the light launched by the light guide and also the light directed to the surface to be examined and the light scattered by them, if e.g. interior walls of the vessels in the human body are to be examined, does not pass twice a layer of blood or body fluid, and the distal end of the endoscope is fixed such that during measurements, shaking and change of relative distances can be largely avoided, whereby the quality at the received optical spectra is considerably improved.
摘要翻译：用于对身体的内表面（2,2'）进行光谱检查的装置，例如，的血管（1），包括具有用于照射所述表面的光导的光谱仪和内窥镜（3），其中在所述光导的近端处被供应光，并且在所述光导的远端处，所述光可以发射到待检查的表面，其中在该内窥镜的远端设置有用于接收被检查表面反射的光的装置，其特征在于，光导的远端布置在具有弹性外部的可充气气球（4），并且从导光体解耦的光和被检查表面反射到接收装置的光在每种情况下穿透气球的外部。以这种方式，由光导发射的光以及指向待检测表面的光和由它们散射的光，如果例如，要检查人体血管的内壁，不要将两层血液或体液通过，并且内窥镜的远端被固定，使得在测量期间可以大大地避免相对距离的晃动和变化从而显着提高了接收光谱的质量。

22. 发明授权

US06574499B1 Mammography method and apparatus 有权
标题翻译：乳房造影方法和装置
公开(公告)号：US06574499B1
公开(公告)日：2003-06-03
申请号：US09448675
申请日：1999-11-24
申请人： Kris A. Dines , Elizabeth Kelly-Fry , Ada Patricia Romilly
发明人： Kris A. Dines , Elizabeth Kelly-Fry , Ada Patricia Romilly
IPC分类号： A61B600
CPC分类号： A61B6/0414 , A61B6/4417 , A61B6/502 , A61B8/0825 , A61B8/4245 , Y10S128/915 , Y10S128/916
摘要： A system for generating a three-dimensional image of the compressed breast 40 of a subject includes an x-ray mammography unit 24 for generating x-ray mammography data, a mechanical scanner 20 including an x-ray mammography compression paddle assembly 22, a control and motion system 26, 28 for driving the mechanical scanner 20 and for sensing the control and motion system's position, an ultrasound probe 32 for generating ultrasound image data in spatial registration with the x-ray mammography unit 24, and a computer 38 for generating from the ultrasound image data and the x-ray mammography data the three-dimensional ultrasound image. A method of examining a breast of a subject includes contacting an anterior surface of the breast with a compression paddle, applying pressure to the anterior surface of the breast with the compression paddle to compress it to reduce the thickness of the breast tissue, passing an ultrasound beam having a frequency greater than 3 MHz, perferrably about 5 MHZ or more, through the paddle and the compressed breast tissue, receiving echoes from the compressed breast tissue through the compression paddle, and converting the echoes into breast examination data.
摘要翻译：用于产生受试者的压缩乳房40的三维图像的系统包括：用于产生x射线乳腺X线照相术数据的X射线乳腺摄影单元24;包括x射线乳房X射线摄影压缩桨组件22的机械扫描仪20，以及用于驱动机械扫描器20并用于感测控制和运动系统的位置的运动系统26,28，用于产生与x射线乳房X射线摄影单元24空间对准的超声图像数据的超声波探头32，以及用于从超声图像数据和X射线乳腺摄影数据的三维超声图像。检查受试者的乳房的方法包括使乳房的前表面与压缩桨接触，用压缩桨对乳房的前表面施加压力以将其压缩以减小乳房组织的厚度，使超声波通过桨和压缩的乳房组织具有大于3MHz的频率，大约5MHz或更大的频率的束，通过压缩桨接收来自压缩的乳房组织的回波，并将回波转换成乳房检查数据。

23. 发明授权

US06567690B2 Method and apparatus for probe localization in brain matter 失效
公开(公告)号：US06567690B2
公开(公告)日：2003-05-20
申请号：US09847997
申请日：2001-05-03
申请人： Cole Giller , Hanli Liu
发明人： Cole Giller , Hanli Liu
IPC分类号： A61B600
CPC分类号： A61B1/00147 , A61B5/0073 , A61B5/0075 , A61B5/0084 , A61B5/04001 , A61B5/064 , A61B5/743
摘要： Method and apparatus for probe localization in brain matter. A method is disclosed for determining the insertion point for an object at a desired location within tissue of varying types. The parameters of tissue are first measured at an entry point into the tissue from exterior thereof. The parameters of the tissue are then measured periodically along a line extending from the entry point and moving away therefrom. A determination is then made if at least one boundary between tissue types has occurred during the measurement process. The measurements along the line are then compared to a predetermined map of the tissue boundaries. Thereafter, a point on the map is then selected corresponding to the desired location within the tissue when the measured parameters indicate that the measurements are taking place in proximity thereto.

24. 发明授权

US06567687B2 Method and system for guiding a diagnostic or therapeutic instrument towards a target region inside the patient's body 有权
公开(公告)号：US06567687B2
公开(公告)日：2003-05-20
申请号：US09900042
申请日：2001-07-09
申请人： Yaron Front , Gal Ben-David
发明人： Yaron Front , Gal Ben-David
IPC分类号： A61B600
CPC分类号： A61B6/5235 , A61B6/032 , A61B6/037 , A61B6/12 , A61B34/20 , A61B90/11 , A61B90/36 , A61B90/39 , A61B2034/107 , A61B2034/2072 , A61N5/1049
摘要： Method and system are presented for guiding a diagnostic or therapeutic instrument towards a correct target inside the patient's body. A combined image obtained by registering structural and functional images of at least a portion of the patient's body including the target is used together with a guiding device. The guiding device has an indicator associated with the instrument, and is operable for presenting data indicative of a position of a location on the instrument relative to any other point in the at least portion of the patient's body. The guiding device is connectable to a computer device displaying the combined image and operable thereby for guiding the instrument towards the target.

25. 发明授权

US06553093B2 Radiation tomography device 失效
公开(公告)号：US06553093B2
公开(公告)日：2003-04-22
申请号：US10096679
申请日：2002-03-14
申请人： Shiro Oikawa
发明人： Shiro Oikawa
IPC分类号： A61B600
CPC分类号： A61B6/4429 , A61B6/032
摘要： In a radiation tomography device, in case a wide photographing area is required, even if a resolution capability in a depth direction of a section of a subject including an intersection of a rotation axis and a radiation irradiating axis is low, a small Laminographic angle &agr;1 is set. In case a high resolution capability is required in the depth direction, even if the photographing area is narrow, a large Laminographic angle &agr;2 is set. Since a balance between the resolution capability in the depth direction of the subject and the photographing area can be adjusted by varying the Laminographic angle, the photographing modes can be freely selected to thereby carry out the tomography suitable for the photographing requirement.

26. 发明授权

US06549803B1 Method and apparatus for targeting material delivery to tissue 有权
标题翻译：用于将材料输送到组织的方法和装置
公开(公告)号：US06549803B1
公开(公告)日：2003-04-15
申请号：US09566478
申请日：2000-05-08
申请人： Raghu Raghavan , Timothy Poston , Raju R. Viswanathan
发明人： Raghu Raghavan , Timothy Poston , Raju R. Viswanathan
IPC分类号： A61B600
CPC分类号： A61M5/14 , A61M2005/14208 , A61M2005/14292 , G06F19/00
摘要： Movement of material in an organism, such as a drug injected into a brain, is modeled by a uniformly structured field of static constants governing transport by moving fluid and diffusion within the fluid. This supports planning of material introduction, (e.g., infusion, perfusion, retroperfusion, injections, etc.) to achieve a desired distribution of the material, continuing real-time feedback as to whether imaged material is moving as planned and will be distributed as desired, and real-time plan modification to improve results.
摘要翻译：通过均匀结构化的静态常数场，通过移动流体和流体内的扩散来控制运输的生物体中的物质的运动，例如注射到脑中的药物。这支持材料介绍（例如输液，灌注，灌注，注射等）的规划，以实现材料的所需分布，持续实时反馈成像材料是否按计划移动，并将根据需要分布，并实时计划修改，以提高结果。

27. 发明授权

US06549802B2 Seed localization system and method in ultrasound by fluoroscopy and ultrasound fusion 有权
标题翻译：通过荧光透视和超声融合进行超声造影定位系统和方法
公开(公告)号：US06549802B2
公开(公告)日：2003-04-15
申请号：US09875031
申请日：2001-06-07
申请人： Kenneth B Thornton
发明人： Kenneth B Thornton
IPC分类号： A61B600
CPC分类号： A61N5/1048 , A61B6/12 , A61B6/5247 , A61B8/0833 , A61B8/0841 , A61B8/4416 , A61N5/1027 , A61N2005/1012
摘要： A seed localization system and method in which a computer-based system is used to determine the three-dimensional (3D) position of radiotherapy seeds with respect to an area of affected tissue, such as the prostate, using ultrasound (US) and fluoroscopy (FL) imaging, so that a radiotherapy dose may be calculated. One embodiment the present invention may be used to determine the 3D position of implanted brachytherapy seeds. An alternative embodiment of the invention may be used to determine the 3D position of implanted objects other than brachytherapy seeds. The seed localization system and method includes a graphical user interface useful for assisting a user of the seed localization system in its operation.
摘要翻译：种子定位系统和方法，其中使用基于计算机的系统来确定放射治疗种子相对于受影响组织的区域（例如前列腺）的三维（3D）位置，其使用超声（US）和荧光透视（ FL）成像，从而可以计算放射治疗剂量。本发明的一个实施例可以用于确定植入的近距离放射治疗种子的3D位置。本发明的替代实施例可用于确定除近距离放射疗法种子之外的植入物体的3D位置。种子定位系统和方法包括用于在其操作中辅助种子定位系统的用户的图形用户界面。

28. 发明授权

US06526117B1 Method and apparatus to minimize phase misregistration artifacts in gated CT images 失效
标题翻译：用于最小化门控CT图像中相位重合失调的方法和装置
公开(公告)号：US06526117B1
公开(公告)日：2003-02-25
申请号：US10044672
申请日：2001-11-09
申请人： Darin R. Okerlund , Sankar V. Srinivas , Jerome F. Knoplioch
发明人： Darin R. Okerlund , Sankar V. Srinivas , Jerome F. Knoplioch
IPC分类号： A61B600
CPC分类号： G06T11/005 , A61B6/027 , A61B6/032 , A61B6/4085 , A61B6/503 , A61B6/541 , G06T2211/412
摘要： A method and apparatus for generating an optimally registered working set of two-dimensional CT images in a gated CT system, the method including, where an acquisition period is divided into sequential acquisition phases, obtaining CT image data for separate phase ranges during each acquisition phase, generating phase image sets including 2D images for each phase range and selecting one phase range image set corresponding to each acquisition phase to generate a working image set where the selected phase range image sets are optimally aligned.
摘要翻译：一种用于在门控CT系统中生成二维CT图像的最佳注册工作集的方法和装置，所述方法包括：将获取周期分为顺序获取阶段，在每个采集阶段获得用于分离相位范围的CT图像数据生成包括每个相位范围的2D图像的相位图像集合，并且选择与每个采集相位对应的一个相位范围图像集合，以生成所选择的相位图像集合被最佳对准的工作图像集。

29. 发明授权

US06512807B1 Low signal correction for perfusion measurements 失效
标题翻译：低信号校正灌注测量
公开(公告)号：US06512807B1
公开(公告)日：2003-01-28
申请号：US09990536
申请日：2001-11-21
申请人： Scott Kenneth Pohlman , Zhongmin Steve Lin
发明人： Scott Kenneth Pohlman , Zhongmin Steve Lin
IPC分类号： A61B600
CPC分类号： A61B6/481 , A61B5/0263 , A61B6/504 , A61B6/507 , Y10S378/901
摘要： A CT scanner (10) for obtaining a medical diagnostic image of a subject includes a stationary gantry (12), and a rotating gantry (14) rotatably supported on the stationary gantry (12) for rotation about the subject. In a perfusion study 130 time-density curves of voxels of an imaging region are computed. In a low signal identification step (132), all voxels with low signal are identified. In a clustering step (134), low signal voxels are clustered together. In a representative determination step (136) representative time-density curves are computed. In a functional measurement step (138), measurements are calculated from the combined and uncombined time-density values. In an assigning step (140), each low signal voxel is assigned the values determined for its group. In a combining step (142) the results of the low and normal signal voxels are combined to produce a single functional perfusion image.
摘要翻译：用于获得对象的医学诊断图像的CT扫描器（10）包括固定机架（12）和可旋转地支撑在固定机架（12）上以围绕被摄体旋转的旋转机架（14）。在灌注研究中，计算了成像区域的体素的时间密度曲线。在低信号识别步骤（132）中，识别出具有低信号的所有体素。在聚类步骤（134）中，低信号体素聚集在一起。在代表性确定步骤（136）中，计算代表时间密度曲线。在功能测量步骤（138）中，从组合和未组合的时间密度值计算测量值。在分配步骤（140）中，为每个低信号体素分配为其组确定的值。在组合步骤（142）中，低和正常信号体素的结果被组合以产生单个功能灌注图像。

30. 发明授权

US06512240B1 Method and apparatus for reading a radiation image that has been stored in a photostimulable screen 失效
标题翻译：用于读取已经存储在可光激励屏幕中的辐射图像的方法和装置
公开(公告)号：US06512240B1
公开(公告)日：2003-01-28
申请号：US09595487
申请日：2000-06-16
申请人： Paul Leblans , Luc Struye
发明人： Paul Leblans , Luc Struye
IPC分类号： A61B600
CPC分类号： C09K11/7733 , A61B6/4216 , A61B6/502 , G01T1/2012 , G01T1/2014 , G01T1/2016 , G21K4/00
摘要： A radiation image read out method and apparatus including stimulating a divalent europium activated cesium halide phosphor screen wherein the halide is at least one of chloride and bromide, that has been exposed to a radiation image, detecting light emitted by the phosphor screen upon stimulation, and erasing the phosphor screen by exposing it to erasing light emitted by at least one laser source.
摘要翻译：一种放射线图像读出方法和装置，包括刺激二价铕活化铯卤化物荧光屏，其中卤化物是已经暴露于辐射图像中的氯化物和溴化物中的至少一种，在刺激时检测由荧光屏发射的光，以及通过将荧光屏暴露于擦除由至少一个激光源发射的光来消除荧光屏。

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