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21. 发明授权

US5985559A System and method for preventing, diagnosing, and treating genetic and pathogen-caused disease 失效
标题翻译：用于预防，诊断和治疗遗传和病原体引起的疾病的系统和方法
公开(公告)号：US5985559A
公开(公告)日：1999-11-16
申请号：US850840
申请日：1997-05-03
申请人： Stephen J. Brown
发明人： Stephen J. Brown
IPC分类号： A61B5/00 , A61B5/087 , G06F19/00 , C12Q1/68 , C12M1/34 , C12M3/00 , G01N33/48
CPC分类号： A61B5/0002 , A61B5/416 , A61B5/4839 , A61B5/6896 , G06F19/3412 , G06F19/3418 , G06F19/363 , A61B2560/0443 , A61B5/0205 , A61B5/087 , A61B5/14532 , G06F19/322
摘要： Genetic testing allows an individual to determine whether or not he or she has a predisposition to a certain disease. The degree of expressivity of a certain disease will be determined in part by an individual's environment and lifestyle. The present invention interprets a patient's gene sequence and his or her environment and lifestyle to come up with a personalized prognosis. This procedure can be repeated many times over the course of a disease state to monitor a patient's condition. In addition, disease-causing pathogens can also have their genes sequenced. Using these sequences in combination with information about a patient's environment and lifestyle, it is possible to come up with a personalized treatment plan, ideally to eliminate the pathogen. It is also possible to use the procedure described above to monitor the course of the disease-state produced by a pathogen. Finally, a genotype-to-phenotype map or database can be constructed for developing better treatments and for research purposes.
摘要翻译：遗传测试允许个人确定他或她是否具有某种疾病的倾向。某种疾病的表现程度将部分由个人的环境和生活方式决定。本发明解释患者的基因序列及其环境和生活方式，以求出个性化的预后。该过程可以在疾病状态的过程中重复多次以监测患者的状况。此外，致病病原体也可以使其基因测序。使用这些序列与患者的环境和生活方式的信息相结合，可以提出个性化的治疗计划，理想地消除病原体。也可以使用上述程序来监测由病原体产生的疾病状态的过程。最后，可以构建基因型到表型图或数据库，以开发更好的治疗和研究目的。

22. 发明授权

US5961332A Apparatus for processing psychological data and method of use thereof 失效
标题翻译：用于处理心理数据的装置及其使用方法
公开(公告)号：US5961332A
公开(公告)日：1999-10-05
申请号：US600771
申请日：1996-02-13
申请人： Raymond Anthony Joao
发明人： Raymond Anthony Joao
IPC分类号： G06F19/00 , G09B19/00
CPC分类号： G06F19/363 , G06F19/3418 , Y10S128/923
摘要： An improvement to an apparatus for processing psychological data, said apparatus comprising means for processing data indicative of at least one of an individual's psychological condition, psychological states, concomitant physiological states, and states of dysfunction in conjunction with at least one of psychological, concomitant physiological, and psycho pathological, at least one of principles, theories and research data in order to generate data indicative of at least one of a diagnosis and a treatment plan for the individual, the improvement comprising a remote user interactive means for providing at least one of a remote accessing and utilization of said apparatus, said remote user interactive means further comprising a user input means for inputting data pertaining to an individual and a user display means for providing at least one of an indication of apparatus operation and data relevant to an individual, wherein said remote user interactive means facilitates at least one of data entry and control over said apparatus, and further wherein data pertinent to at least one of an individual's diagnosis and treatment plan is obtained from said apparatus via said remote user interactive means. A method of use of the improved apparatus is also disclosed.
摘要翻译：用于处理心理数据的装置的改进，所述装置包括用于处理指示个人的心理状况，心理状态，伴随的生理状态和功能障碍状态中的至少一个的数据的装置，其结合至少一种心理和伴随的生理学以及精神病理学，原理，理论和研究数据中的至少一个，以便产生指示个体的诊断和治疗计划中的至少一个的数据，所述改进包括远程用户交互装置，用于提供以下各项中的至少一个：远程访问和利用所述设备，所述远程用户交互装置还包括用于输入与个人有关的数据的用户输入装置和用于提供设备操作的指示和与个人相关的数据中的至少一个的用户显示装置，其中所述远程用户交互装置有助于至少一个数据输入和控制，并且其中，经由所述远程用户交互装置从所述装置获得与个人诊断和治疗计划中的至少一个有关的数据。还公开了改进装置的使用方法。

23. 发明授权

US5953704A Health care management system for comparing user-proposed and recommended resources required for treatment 失效
标题翻译：医疗管理系统用于比较治疗所需的用户建议和推荐资源
公开(公告)号：US5953704A
公开(公告)日：1999-09-14
申请号：US784185
申请日：1997-01-15
申请人： Gary Thomas McIlroy , Julie Ellen Kees , Jacquelyn Ann Kalscheuer
发明人： Gary Thomas McIlroy , Julie Ellen Kees , Jacquelyn Ann Kalscheuer
IPC分类号： G06F19/00 , G06F17/60
CPC分类号： G06F19/327 , G06F19/325 , G06F19/3443 , G06F19/345 , G06F19/3481 , G06Q50/22 , G06F19/363
摘要： A health care management system for use by hospitals, physicians, insurance companies, health maintenance organizations, and others in the health care field includes a processing unit and health condition guidelines. A user inputs information related to the health condition of an individual and guideline treatment options are identified. The user also inputs actual or proposed and final recommendation treatments for the same individual. The resulting comparative information can be used to modify the actual or proposed treatment, or provide explanatory information as to reasons for the difference between the final recommendation treatment and guideline treatment options. Also, the comparative information can be used by a reviewer for evaluation or utilization purposes.
摘要翻译：卫生保健管理系统由卫生保健领域的医院，医师，保险公司，保健机构等人员使用，包括处理单位和健康状况指导原则。用户输入与个人的健康状况相关的信息和指南治疗选项。用户还输入相同个人的实际或建议和最终推荐治疗。所得到的比较信息可用于修改实际或拟议的治疗，或提供关于最终推荐治疗和指南治疗方案之间差异的原因的说明信息。此外，比较信息可以由审阅者用于评估或利用目的。

24. 发明授权

US5596994A Automated and interactive behavioral and medical guidance system 失效
标题翻译：自动和互动的行为和医疗指导系统
公开(公告)号：US5596994A
公开(公告)日：1997-01-28
申请号：US237261
申请日：1994-05-02
申请人： William L. Bro
发明人： William L. Bro
IPC分类号： A61G12/00 , H04M3/42 , H04M3/46 , H04M3/493 , H04M3/51 , H04M11/00 , A61B5/04
CPC分类号： G06F19/3481 , G06F19/3456 , G06F19/363 , G09B19/00 , G09B7/04 , H04M11/00 , H04M3/46 , H04M3/465 , H04M3/493 , H04M3/5158 , H04M2201/40 , H04M3/42221 , Y10S128/904 , Y10S128/905 , Y10S128/92 , Y10S128/925 , Y10S379/903 , Y10S379/904
摘要： An automated and interactive positive motivation system (10) that allows a physician, counselor or trainer to produce and send a series of motivational messages and/or questions to a client (50) to change or reinforce a specific behavioral problem. The system (10) consists of a client database (12) and a client program (14) that includes for each client unique motivational messages and/or questions based on the transtheoretical model of change comprising the six stages of behavioral change (100) and the 14 processes of change (114), as interwinding, interacting variables in the modification of health and mental health behaviors of the client (50). The client program (14) utilizes the associated 14 processes of change (114) to move the client (50) through one of the six stages of behavioral change (100) when appropriate by using a plurality of transmission and receiving means. The database and program are operated by a computer (16) that at preselected time periods sends the messages and/or questions to the client (50) through use of a variety of transmission means and furthermore selects a platform of behavioral issues that is to be addressed based on a given behavioral stage (100) at a given time of day.
摘要翻译：一种自动化和互动的积极动机系统（10），其允许医师，顾问或培训者向客户（50）产生并发送一系列激励消息和/或问题以改变或加强特定的行为问题。系统（10）由客户数据库（12）和客户程序（14）组成，客户端程序（14）包括针对每个客户端的独特的激励消息和/或基于包括六个行为改变阶段（100）的变革的理论模型的问题，和 14个改变过程（114）作为客户健康和心理健康行为改变中的相互作用的相互作用变量（50）。客户端程序（14）利用相关联的14个改变过程（114），通过使用多个发送和接收装置适当地使客户机（50）通过六个行为改变阶段（100）之一移动。数据库和程序由计算机（16）操作，在预选的时间段通过使用各种传输装置将消息和/或问题发送给客户端（50），并且还选择一个行为问题的平台根据给定的行为阶段（100）在一天的给定时间处理。

25. 发明授权

US5583758A Health care management system for managing medical treatments and comparing user-proposed and recommended resources required for treatment 失效
标题翻译：用于管理医疗的医疗保健管理系统，并比较治疗所需的用户建议和推荐资源
公开(公告)号：US5583758A
公开(公告)日：1996-12-10
申请号：US475523
申请日：1995-06-07
申请人： Gary T. McIlroy , Julie E. Kees , Jacquelyn A. Kalscheuer
发明人： Gary T. McIlroy , Julie E. Kees , Jacquelyn A. Kalscheuer
IPC分类号： G06F19/00 , G06F17/60
CPC分类号： G06F19/327 , G06F19/325 , G06F19/3443 , G06F19/345 , G06F19/3481 , G06Q50/22 , G06F19/363
摘要： A health care management system for use by hospitals, physicians, insurance companies, health maintenance organizations, and others in the health care field includes a processing unit and health condition guidelines. A user inputs information related to the health condition of an individual and guideline treatment options are identified. The user also inputs actual or proposed and final recommendation treatments for the same individual. The resulting comparative information can be used to modify the actual or proposed treatment, or provide explanatory information as to reasons for the difference between the final recommendation treatment and guideline treatment options. Also, the comparative information can be used by a reviewer for evaluation or utilization purposes.
摘要翻译：卫生保健管理系统由卫生保健领域的医院，医师，保险公司，保健机构等人员使用，包括处理单位和健康状况指导原则。用户输入与个人的健康状况相关的信息和指南治疗选项。用户还输入相同个人的实际或建议和最终推荐治疗。所得到的比较信息可用于修改实际或拟议的治疗，或提供关于最终推荐治疗和指南治疗方案之间差异的原因的说明信息。此外，比较信息可以由审阅者用于评估或利用目的。

26. 发明授权

US5473537A Method for evaluating and reviewing a patient's condition 失效
标题翻译：评估和评估患者状况的方法
公开(公告)号：US5473537A
公开(公告)日：1995-12-05
申请号：US420854
申请日：1995-04-12
申请人： William M. Glazer , Geoffrey V. Gray
发明人： William M. Glazer , Geoffrey V. Gray
IPC分类号： G06F19/00 , G06F159/00
CPC分类号： G06F19/327 , G06F19/3481 , G06F19/322 , G06F19/3487 , G06F19/363 , Y10S128/92
摘要： A method for evaluating and/or reviewing a patient's condition comprises the steps of: collecting clinical data relevant to a determination about the propriety of a particular level of care for a patient; generating a behavioral severity series for the patient; and deriving a recommended treatment intensity from the behavioral severity series. The method is preferably performed using a computer to collect the clinical data. The computer can be programmed to automatically generate the behavioral severity series and derive the recommended treatment intensity for the patient.
摘要翻译：用于评估和/或检查患者状况的方法包括以下步骤：收集与关于对患者的特定水平的护理的适当性的确定相关的临床数据; 为患者产生行为严重性系列; 并从行为严重性系列推导出推荐的治疗强度。该方法优选使用计算机进行以收集临床数据。可以对计算机进行编程，以自动生成行为严重性系列，并为患者推导出推荐的治疗强度。

27. 发明授权

US5282474A Method and system for the evaluation and visual display of abnormal electromagnetic physiological activity of the brain and the heart 失效
标题翻译：用于评估和视觉显示脑和心脏异常电磁生理活动的方法和系统
公开(公告)号：US5282474A
公开(公告)日：1994-02-01
申请号：US790383
申请日：1991-11-08
申请人： Pedro A. Valdes Sosa , Rolando B. Lirio , Roberto D. Pascual Marqui , Livia N. Blaquier , Lidice G. Garcia , Juan C. Jimenez Sobrino , Jorge B. Bayard
发明人： Pedro A. Valdes Sosa , Rolando B. Lirio , Roberto D. Pascual Marqui , Livia N. Blaquier , Lidice G. Garcia , Juan C. Jimenez Sobrino , Jorge B. Bayard
IPC分类号： G06F19/00 , A61B5/0205
CPC分类号： G06F19/3487 , G06F19/3437 , G06F19/3406 , G06F19/363
摘要： A method and system for the evaluation and visual display of abnormal electromagnetic physiological activity of the brain and the heart utilizes a set of bioelectric amplifiers and a computer based system for the recording and analog to digital conversion of human electrophysiological signals. The signals collected are expanded in selected spatio-temporal functional bases, and parametric models are used for summarizing the statistical properties of the coefficients. Multivariate topographic maps and curves are computed based on the comparison of the estimated parameters for a patient and the regression equations for the parameters calculated from a normative database. The multivariate maps and curves are visually displayed in a diagnostically useful color-coded probability scale.
摘要翻译：用于评估和视觉显示脑和心脏异常电磁生理活动的方法和系统利用一组生物电力放大器和基于计算机的系统用于人类电生理信号的记录和模数转换。收集的信号在选定的时空功能基础上扩展，参数模型用于总结系数的统计特性。基于对患者的估计参数的比较和从规范数据库计算的参数的回归方程计算多变量地形图和曲线。多变量图和曲线以诊断上有用的颜色编码概率标尺显示。

28. 发明授权

US5170362A Redundant system for interactively evaluating the capabilities of multiple test subjects to perform a task utilizing a computerized test system 失效
标题翻译：冗余系统，用于交互地评估多个测试对象的能力，以使用计算机化测试系统执行任务
公开(公告)号：US5170362A
公开(公告)日：1992-12-08
申请号：US641218
申请日：1991-01-15
申请人： Howard L. Greenberg , Ensor Rodriguez
发明人： Howard L. Greenberg , Ensor Rodriguez
IPC分类号： G06F19/00 , G09B7/04
CPC分类号： G09B7/04 , G06F19/3418 , G06F19/363 , G06F19/322
摘要： A redundant interactive subject evaluation system composed of multiple, distinct test sites containing multiple test stations, nodes which interconnect several test sites and a single integrating evaluating hub into which flows all site and node data. The system is operable to receive dial-in telecommunications data from any remote test site location including transportation vehicles in transit by air, water, or land. System reliability is high with continued node and test site activity even during overall system outages. The performance evaluation test runs on the test stations at the individual sites interactively evaluating the performance capabilities of multiple subjects by comparing the test subjects' hub data stored as historical performance characteristics with their new test results secured at the test stations. Trained, evaluating personnel not located at the test sites such as Medical Review Officers (MRO's) are located at the nodes and hub to analyze, evaluate and interpret data received from the test subject's results at the remote sites. One embodiment of the system is described in detail.
摘要翻译：由多个不同的测试站点组成的冗余交互主题评估系统，包含多个测试站，连接多个测试站点的节点和流入所有站点和节点数据的单个集成评估中心。该系统可操作以从任何远程测试地点的位置接收拨入电信数据，包括通过空运，水或陆地运输的运输车辆。系统可靠性高，即使在整个系统中断期间，持续的节点和测试站点活动也是如此。通过将存储为历史性能特征的测试对象的集线器数据与在测试站保证的新测试结果进行比较，性能评估测试在各个站点的测试站上进行交互式评估多个主题的性能能力。受过训练的评估人员不在医疗检查主任（MRO）等测试点的人员位于节点和集线器上，以分析，评估和解释从远程站点的测试对象结果中收到的数据。详细描述系统的一个实施例。

29. 发明授权

US5025374A Portable system for choosing pre-operative patient test 失效
标题翻译：便携式系统，用于选择术前患者测试
公开(公告)号：US5025374A
公开(公告)日：1991-06-18
申请号：US130934
申请日：1987-12-09
申请人： Michael Roizen , William E. Turcotte, II , Richard E. Pfisterer
发明人： Michael Roizen , William E. Turcotte, II , Richard E. Pfisterer
IPC分类号： G06F15/02 , G06F19/00 , G09B7/04
CPC分类号： G09B7/04 , G06F15/025 , G06F19/3406 , G06F19/3487 , G06F19/363 , G06Q50/22 , G06F19/322 , G06F19/3412 , Y10S128/92
摘要： An interactive medical test selector for use by a patient is about the size of a book and has a screen for displaying questions to a patient, a limited number of keys by which the patient can enter answers, and a memory device for storing the patient's answers. The test selector is battery-powered for portability and uses a low-power liquid crystal display or the like to display instructions and medical questions to the patient. Only four keys are seen or used by the patient for answering the questions: YES, NO, NOT SURE, and NEXT QUESTION. Additional control keys used by the medical staff are hidden from the patient. The device is controlled by a pre-programmed microcomputer on a chip, and a ROM-based, removable and replaceable control program which not only collects, but also analyzes the patient's answers and makes appropriate recommendations based on those answers, and drives a remote printer or computer terminal.

30. 发明授权

US09008379B2 Pay for studies submitted (PASS) method for clinical trials 有权
标题翻译：支付临床试验提交的研究（PASS）方法
公开(公告)号：US09008379B2
公开(公告)日：2015-04-14
申请号：US12062148
申请日：2008-04-03
申请人： Steven F. Owens , Gudrun Zahlmann , Patrick K. DeGrouchy
发明人： Steven F. Owens , Gudrun Zahlmann , Patrick K. DeGrouchy
IPC分类号： G06K9/00 , G06F19/00 , G06Q50/22
CPC分类号： G06F19/363 , G06F19/00 , G06F19/321 , G06Q50/22 , G16H10/20
摘要： A system and method is disclosed for facilitating the acquisition of medical images used as part of a clinical trials process by requiring Imaging Centers to compete with each other to supply the images. Agreements between the Sponsor and a plurality of Imaging Centers stipulate that the Sponsor is only required to accept a certain total number of medical images and is free to reject any medical images that either do not comply with the protocol, or which exceed the total number of medical images required for the study. This motivates the Imaging Centers to quickly obtain and transmit to the Sponsor high quality medical images that meet the basic requirements outlined in the clinical study protocol, since images are accepted and compensated for by the Sponsor on a first-come, first-served basis. A system for implementing this method is also disclosed.
摘要翻译：公开了一种系统和方法，用于通过要求成像中心彼此竞争以提供图像来促进用作临床试验过程的一部分的医学图像的获取。赞助商和多个成像中心之间的协议规定，赞助商只需要接受一定数量的医疗图像，并且可以免费拒绝任何不符合协议的医疗图像，或超过总数医学图像需要研究。这促使成像中心快速获得并向赞助商传送符合临床研究方案中概述的基本要求的高质量医学图像，因为图像以先到先得的方式被赞助商接受和补偿。还公开了一种用于实现该方法的系统。

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