专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

21. 发明申请

US20180202966A1 ION-SENSING CHARGE-ACCUMULATION CIRCUITS AND METHODS 审中-公开
公开(公告)号：US20180202966A1
公开(公告)日：2018-07-19
申请号：US15789850
申请日：2017-10-20
申请人： LIFE TECHNOLOGIES CORPORATION
发明人： Keith FIFE
IPC分类号： G01N27/414 , G01N27/30
CPC分类号： G01N27/414 , G01N27/302 , G01N27/4145 , G01N27/4148
摘要： An ion-sensitive circuit can include a charge accumulation device, to accumulate a plurality of charge packets as a function of an ion concentration of a fluid, and at least one control and readout transistor, to generate an output signal as a function of the accumulated plurality of charge packets, the output signal representing the ion concentration of the solution. The charge accumulation device can include a first charge control electrode above a first electrode semiconductor region, an electrically floating gate structure above a gate semiconductor region and below an ion-sensitive passivation surface, a second charge control electrode above a second electrode semiconductor region, and a drain diffusion region. The first control electrode can control entry of charge into a gate semiconductor region in response to a first control signal. The ion-sensitive passivation surface can be configured to receive the fluid. The second charge control electrode can control transmission of the plurality of charge packets out of the gate semiconductor region and into the drain diffusion region in response to a second control signal. The drain diffusion region can receive the plurality of charge packets from the gate semiconductor region via the second electrode semiconductor region.

22. 发明授权

US09976125B2 FAD-conjugated glucose dehydrogenase gene 有权
公开(公告)号：US09976125B2
公开(公告)日：2018-05-22
申请号：US15496935
申请日：2017-04-25
申请人： Ikeda Food Research Co., Ltd.
发明人： Takako Yada , Koji Miyamoto , Michinari Honda
IPC分类号： C12N9/04 , C12Q1/00 , G01N27/30 , G01N27/327 , G01N33/66 , C12Q1/54 , C12Q1/32
CPC分类号： C12N9/0006 , C12Q1/006 , C12Q1/32 , C12Q1/54 , C12Y101/9901 , G01N27/301 , G01N27/302 , G01N27/3271 , G01N33/66 , G01N2333/902 , G01N2333/904 , Y10T29/49117
摘要： An object of the present invention is to provide: a novel gene (polynucleotide) encoding an FAD-conjugated glucose dehydrogenase having excellent properties that it has excellent reactivity to glucose, excellent thermal stability, and excellent substrate-recognition performance and also has a low activity for maltose; a process for the production of the enzyme using a transformant cell transfected with the gene; and a method for the determination of glucose, a reagent composition for use in the determination of glucose, a biosensor for use in the determination of glucose and others, each characterized by using the enzyme obtained. The invention relates to a polynucleotide encoding an FAD-conjugated glucose dehydrogenase, comprising a polypeptide containing an amino acid sequence: X1-X2-X3-X4-X5-X6 (wherein X1 and X2 independently represent an aliphatic amino acid residue; X3 and X6 independently represent a branched amino acid residue; and X4 and X5 independently represent a heterocyclic amino acid residue or an aromatic amino acid residue); and others.

23. 发明授权

US09910006B2 Method for manufacturing a glass assembly and apparatus for executing the method 有权
公开(公告)号：US09910006B2
公开(公告)日：2018-03-06
申请号：US14935805
申请日：2015-11-09
申请人： Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG
发明人： Roland Zilly , Carsten Enderwitz , Torsten Zeidler , Ronny Kuhn
IPC分类号： C03B9/40 , G01N27/28 , C03B9/41 , C03B7/22 , C03B7/00 , G01N27/30 , G01N27/333
CPC分类号： G01N27/283 , C03B7/005 , C03B7/22 , C03B9/41 , G01N27/302 , G01N27/333
摘要： A method for manufacturing a glass assembly comprises the steps: lowering of a dip pipe that gas may flow through vertically to the surface of a glass melt; determining when the surface of the glass melt is encountered by the dip pipe end showing towards the glass melt by detecting an increase of the gas pressure found inside the dip pipe; continued lowering of the dip pipe until a predetermined depth of entry of the dip pipe end showing towards the glass melt is reached; obtaining a predetermined pressure inside the dip pipe while the dip pipe first stays at the given immersion depth for the given duration and after the predetermined duration is completed, is lifted with a given speed vertically to the surface of the glass melt, thus creating a gas bubble in the glass melt whose walls are attached to the end of the dip pipe; continued lifting of the dip pipe vertically to the surface of the glass melt until the gas bubble is separated from the glass melt, with the wall of the gas bubble remaining at the dip pipe end as a closing film; and setting, especially controlling and/or adjusting of the pressure inside the dip pipe based on the geometry of the film closing the end of the dip pipe as determined by an image capturing device.

24. 发明授权

US09791398B2 Measurement device with sensor array 有权
公开(公告)号：US09791398B2
公开(公告)日：2017-10-17
申请号：US14343376
申请日：2012-09-06
申请人： William Clark , Sung Kwon Cho , Yuejun Zhao , Timothy J. Syciarz
发明人： William Clark , Sung Kwon Cho , Yuejun Zhao , Timothy J. Syciarz , R. Maxwell Flaherty , J. Christopher Flaherty , David W. Wagner
IPC分类号： G01N27/28 , G01N27/30 , B01L3/00 , G01N27/403 , G01N33/483
CPC分类号： G01N27/302 , B01L3/502738 , B01L2200/027 , B01L2200/0673 , B01L2300/0645 , B01L2300/0816 , B01L2300/0829 , B01L2300/087 , B01L2300/1827 , B01L2400/0406 , B01L2400/0427 , B01L2400/049 , B01L2400/0677 , G01N27/28 , G01N27/307 , G01N27/4035 , G01N33/4836
摘要： A system for obtaining a pH measurement includes a disposable probe and a reader. The disposable probe comprises multiple indicating electrodes and at least one reference electrode. The reader is configured to operably engage with the disposable probe and provide pH information of a sample.

25. 发明申请

US20170205372A1 ELECTROCHEMICALLY ACTIVE AGENTS FOR PH MODULATION IN BIOLOGICAL BUFFERS 审中-公开
公开(公告)号：US20170205372A1
公开(公告)日：2017-07-20
申请号：US15477780
申请日：2017-04-03
申请人： Robert Bosch GmbH
发明人： Christopher Johnson , Sam Kavusi , Nadezda Fomina , Habib Ahmad , Autumn Maruniak , Christoph Lang , Ashwin Raghunathan
IPC分类号： G01N27/416 , G01N27/30 , C12Q1/00
CPC分类号： G01N27/4167 , C07C37/00 , C07C37/07 , C07C39/10 , C07C39/11 , C07C41/01 , C07C41/24 , C07C41/30 , C07C43/1783 , C07C43/2055 , C07C43/225 , C07C43/23 , C07C45/42 , C07C46/06 , C07C49/82 , C07C49/84 , C12Q1/001 , C12Q1/004 , G01N27/302 , G01N27/327 , G01N27/3275 , G01N27/4163 , G01N33/5438
摘要： Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.

26. 发明授权

US09689828B2 Passive wireless sensor 有权
公开(公告)号：US09689828B2
公开(公告)日：2017-06-27
申请号：US14353191
申请日：2012-10-10
申请人： UNIVERSITY OF MANITOBA
发明人： Greg E. Bridges , Douglas L. Thomson , Sharmistha Bhadra , Michael Freund
IPC分类号： G01N15/06 , G01N33/00 , G01N33/48 , G01N27/00 , G01N27/30 , H04Q9/00 , G01N33/18 , G01D3/032 , G01K7/24
CPC分类号： G01N27/302 , G01D3/032 , G01K7/24 , G01N33/18 , H04Q9/00 , H04Q2209/40 , H04Q2209/47 , H04Q2209/75
摘要： Systems, devices, and/or methods for use in passive wireless transmission of one or more parameters such as, e.g., pH, temperature, etc. are described. The systems, devices, and/or methods may use a passive sensor located proximate a material and an interrogator that may be used to interrogate the passive sensor and to receive a signal from the passive sensor representative of the one or more parameters.

27. 发明申请

US20170146478A1 ANALYTE SENSOR 审中-公开
公开(公告)号：US20170146478A1
公开(公告)日：2017-05-25
申请号：US15220277
申请日：2016-07-26
申请人： Senova Systems, Inc.
发明人： Eric Lee , Mark Micklatcher , Jai Krishnamurthy
IPC分类号： G01N27/30 , C08F8/00 , C07F17/02 , C08G77/18 , C07F7/18 , G01N27/333 , C08G77/22
CPC分类号： G01N27/302 , C07F7/081 , C07F7/1804 , C07F17/02 , C08F8/00 , C08G77/18 , C08G77/22 , C08G2220/00 , C08L2312/08 , G01N27/30 , G01N27/301 , G01N27/3335
摘要： Matrix materials, such as sol-gels and polymers derivatives to contain a redox active material can be used to form electrodes and probes suitable for use in pH meters and other analyte sensing devices.

28. 发明申请

US20170101329A1 INHIBITION OF SENSOR BIOFOULING 审中-公开
公开(公告)号：US20170101329A1
公开(公告)日：2017-04-13
申请号：US15290819
申请日：2016-10-11
申请人： SCHLUMBERGER TECHNOLOGY CORPORATION
发明人： Nathan Scott Lawrence , Steven Antony Gahlings
IPC分类号： C02F1/46 , G01N21/15 , G01N27/30 , G01N27/38 , C02F1/461 , G01N27/416
CPC分类号： C02F1/4602 , C02F1/46109 , C02F1/4672 , C02F1/722 , C02F2001/46142 , C02F2103/08 , C02F2209/008 , C02F2209/06 , C02F2209/225 , C02F2209/265 , C02F2303/20 , C02F2305/023 , G01N21/15 , G01N21/552 , G01N21/59 , G01N27/302 , G01N27/38 , G01N27/4167 , G01N33/1826
摘要： Generating hydrogen peroxide in situ in a water environment to mitigate biofouling of a water sensor. A hydrogen peroxide generator submerged in the water environment generates hydrogen peroxide to remove/mitigate biofouling of the water sensor. The water sensor may be an electrochemical sensor and the hydrogen peroxide generator may be an electrochemical system that is integrated with the sensor. The water sensor may be able to operate without interference from the generated hydrogen peroxide.

29. 发明申请

US20160363578A1 APPARATUS FOR DETERMINING MEASUREMENT VARIABLES AT MEMBRANES 审中-公开
标题翻译：用于确定膜上测量变量的装置
公开(公告)号：US20160363578A1
公开(公告)日：2016-12-15
申请号：US15121370
申请日：2015-02-18
申请人： CYTOCENTRICS BIOSCIENCE GMBH
发明人： Thomas Knott , Michael Huber , Peter Van Stiphout
IPC分类号： G01N33/487 , G01N27/30 , G01N27/327 , G01N27/416
CPC分类号： G01N33/48728 , G01N27/302 , G01N27/304 , G01N27/327 , G01N27/4166 , G01N27/4167
摘要： An apparatus for determining preferably Biologically Relevant Measurement Variables at membranes has at least one first plate-like or film-like substrate, which is made from at least one first material and has continuous openings or pores or can be perforated, and also has a second plate-like or film-like substrate which is made from at least one second material, to which measuring elements are assigned or on which measuring elements are situated. Cells or similar structures may be at least temporarily applied or permanently cultivated on the first substrate. According to the invention, the first substrate and the second substrate are assigned to one another at least during the measuring operation for determining the corresponding measurement variables, specifically preferably on flat sides which are opposite one another. In particular, this assignment is a connection of the two substrates, preferably a joining-together.
摘要翻译：用于在膜上优选确定生物相关测量变量的装置具有至少一个第一板状或薄膜状基底，其由至少一种第一材料制成并具有连续的开口或孔或可以穿孔，并且还具有第二由至少一个第二材料制成的板状或薄膜状基材，测量元件被分配到其上或测量元件位于其上。细胞或类似结构可以至少临时施用或永久培养在第一底物上。根据本发明，至少在测量操作期间将第一基板和第二基板彼此分配，以确定对应的测量变量，特别优选在彼此相对的平面上。特别地，该分配是两个基板的连接，优选地连接在一起。

30. 发明授权

US09279781B2 Measuring arrangement and method for registering an analyte concentration in a measured medium 有权
标题翻译：在测量介质中记录分析物浓度的测量布置和方法
公开(公告)号：US09279781B2
公开(公告)日：2016-03-08
申请号：US13767016
申请日：2013-02-14
申请人： Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG
发明人： Thomas Wilhelm , Michael Hanko
IPC分类号： G01N27/416 , G01N27/30 , G01N27/333 , G01N27/49
CPC分类号： G01N27/30 , G01N27/302 , G01N27/333 , G01N27/4167 , G01N27/49
摘要： A measuring arrangement for registering a measured variable representing concentration of an analyte in a measured medium, includes: a first electrode modified with a redox active substance, a second electrode, and a measuring circuit, which comprises a voltage source for applying at least one predetermined voltage between the first electrode and a reference, and an apparatus for registering electrical current flowing, in such case, between the first electrode and the second electrode or for registering a variable correlated with the electrical current flowing between the first electrode and the second electrode, wherein the second electrode is modified with the same redox active substance as the first electrode.
摘要翻译：一种测量装置，用于记录测量介质中分析物浓度的测量变量，包括：用氧化还原活性物质，第二电极和测量电路修饰的第一电极，其包括用于施加至少一个预定的在这种情况下，在第一电极和第二电极之间记录电流的装置，或用于记录与在第一电极和第二电极之间流动的电流相关的变量的装置，其中所述第二电极用与所述第一电极相同的氧化还原活性物质进行改性。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式