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21. 发明申请

US20170140126A1 Integrated Medication and Infusion Monitoring System 审中-公开
公开(公告)号：US20170140126A1
公开(公告)日：2017-05-18
申请号：US15298925
申请日：2016-10-20
申请人： CERNER INNOVATION, INC.
发明人： Alan M. Portnoy , Deborah A. Saeger
IPC分类号： G06F19/00 , A61M5/14
CPC分类号： G06F19/3468 , A61M5/14 , A61M2205/3576 , A61M2205/502 , A61M2205/52 , A61M2205/6072 , G06F19/325 , G06Q10/1093 , G06Q50/24 , G16H10/60
摘要： A system manages IV pumps so that clinicians automatically receive alerts, decisions, and actions required to maintain a patient IV medication therapy according to a prescribed treatment protocol. An infusion pump monitoring system, includes an acquisition processor for acquiring fluid infusion parameters for administration of an infusion fluid to a patient using an infusion pump. A fluid infusion monitor uses acquired fluid infusion parameters for automatically searching a patient medical record for information concerning rate of fluid infusion of a particular infusion fluid and determining if a rate of a previously administered dose of the particular infusion fluid was a lower rate than indicated in the fluid infusion parameters. An interface processor automatically initiates generation of a message indicating a potential adverse reaction to the particular infusion fluid in response to a determination of a lower rate being employed for previously administering the particular infusion fluid.

22. 发明授权

US09649503B2 System and method for optogenetic therapy 有权
公开(公告)号：US09649503B2
公开(公告)日：2017-05-16
申请号：US14444894
申请日：2014-07-28
申请人： Circuit Therapeutics, Inc.
发明人： Scott Delp , Karl Deisseroth , Dan Andersen
IPC分类号： A61N1/00 , A61N5/06 , A61N1/05 , A61N1/36 , A61K38/16 , A61K48/00 , A61K41/00 , A61M25/01 , A61M37/00 , A61K38/17
CPC分类号： A61N5/0601 , A61B17/00234 , A61B17/3403 , A61B2017/3413 , A61K38/16 , A61K38/164 , A61K38/168 , A61K38/177 , A61K41/00 , A61K41/0057 , A61K48/00 , A61K48/0075 , A61M5/142 , A61M5/20 , A61M25/0105 , A61M25/0147 , A61M37/0015 , A61M2037/0023 , A61M2037/0061 , A61M2205/3576 , A61M2205/50 , A61N1/0551 , A61N1/3605 , A61N1/36053 , A61N5/062 , A61N5/0622 , A61N2005/0612 , A61N2005/0626 , A61N2005/0627 , A61N2005/063 , A61N2005/0631 , A61N2005/0643 , A61N2005/0651 , A61N2005/0653 , A61N2005/0665 , A61N2005/067
摘要： Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.

23. 发明申请

US20170124285A1 DEVICES AND METHODS FOR ASSISTING A USER OF A DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：US20170124285A1
公开(公告)日：2017-05-04
申请号：US15315922
申请日：2015-06-03
申请人： AMGEN INC.
发明人： Adam B. McCullough , Ferry Tamtoro , Huaying Yang , Mark Ka Lai Lee , Desheng Yin , Scott R. Gibson , Donald Busby , Peter V. Shultz , Keith P. Kogler , Basel Hasan Taha , Jimmie L. Ward , Steven William Badelt
IPC分类号： G06F19/00 , A61M5/315 , A61M5/32 , A61M5/20
CPC分类号： A61M5/20 , A61M5/14244 , A61M5/14248 , A61M5/158 , A61M5/24 , A61M5/31501 , A61M5/31568 , A61M5/3202 , A61M5/3243 , A61M5/3257 , A61M5/326 , A61M5/5086 , A61M2005/3267 , A61M2205/3331 , A61M2205/3368 , A61M2205/3553 , A61M2205/3576 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/6009 , G06F19/325 , G06F19/3418 , G06F19/3468 , G06Q50/01 , G06Q50/22
摘要： Devices and methods are disclosed for assisting a user of a drug delivery device with an application executing on a mobile computing device. The mobile computing device may receive information from the drug delivery device related to its condition and/or operation and subsequently select an informational and/or instructional prompt to be displayed to the user based on the received information. The mobile computing device may also generate a display in the application including the selected informational prompt and/or the instructional prompt. Accordingly, the user of the drug delivery device can be guided through the drug delivery process in real time, thereby reducing the likelihood of improper or incomplete use of the drug delivery device.

24. 发明授权

US09623198B2 Patch-sized fluid delivery systems and methods 有权
公开(公告)号：US09623198B2
公开(公告)日：2017-04-18
申请号：US12395036
申请日：2009-02-27
申请人： Dean Kamen , Larry B. Gray , Eric Yeaton
发明人： Dean Kamen , Larry B. Gray , Eric Yeaton
IPC分类号： A61M5/32 , A61M5/50 , A61M5/142 , A61M5/145 , A61M5/168 , G05D7/06 , A61M5/172 , G08C17/02 , H04B7/26 , G05B23/02 , A61M5/158 , A61B5/00 , G01F22/00 , A61M5/14 , A61M5/162 , A61M5/36
CPC分类号： A61M5/5086 , A61B5/0024 , A61B5/1427 , A61B5/6833 , A61B2560/0412 , A61J1/20 , A61M5/1413 , A61M5/142 , A61M5/14212 , A61M5/14216 , A61M5/14224 , A61M5/14244 , A61M5/14248 , A61M5/1452 , A61M5/14586 , A61M5/158 , A61M5/162 , A61M5/168 , A61M5/16804 , A61M5/16809 , A61M5/16813 , A61M5/16831 , A61M5/16886 , A61M5/172 , A61M5/1723 , A61M5/365 , A61M2005/1402 , A61M2005/14208 , A61M2005/14252 , A61M2005/14268 , A61M2005/14506 , A61M2005/1583 , A61M2005/1585 , A61M2005/1586 , A61M2005/16863 , A61M2205/0266 , A61M2205/0294 , A61M2205/04 , A61M2205/16 , A61M2205/18 , A61M2205/3303 , A61M2205/3331 , A61M2205/3337 , A61M2205/3368 , A61M2205/3375 , A61M2205/3379 , A61M2205/3523 , A61M2205/3546 , A61M2205/3569 , A61M2205/3576 , A61M2205/3592 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/8206 , A61M2205/8237 , A61M2206/22 , A61M2207/00 , A61M2209/045 , A61M2230/201 , G01F22/00 , G05B23/02 , G05D7/0647 , G05D7/0676 , G08C17/02 , H04B7/2609 , Y10T29/49236 , Y10T29/494 , Y10T29/49412 , Y10T29/49826
摘要： A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.

25. 发明申请

US20170086248A1 ANALYSIS OF WIRELESS COMMUNICATION LINKS BETWEEN MEDICAL DEVICES 审中-公开
公开(公告)号：US20170086248A1
公开(公告)日：2017-03-23
申请号：US15210755
申请日：2016-07-14
申请人： ABBOTT DIABETES CARE INC.
发明人： Mark K. Sloan
IPC分类号： H04W76/02 , H04W24/08 , H04W52/02 , H04B7/26
CPC分类号： H04B7/26 , A61M5/14 , A61M5/14244 , A61M2205/3576 , A61M2205/50 , A61M2205/70 , G06F19/00 , G06F19/3418 , H04B7/24 , H04W24/08 , H04W52/0241 , H04W76/19 , Y02D70/142 , Y02D70/144 , Y02D70/162 , Y02D70/448 , Y02D70/449
摘要： A system and method of processing information regarding medical devices in wireless communication with each other is provided in which a controller device has a first wireless communication link with a first medical device, such as an analyte sensor, and a second wireless communication link with a second medical device, such as a delivery device. A processor in the controller device monitors the status of the first and second wireless links and upon noting a degradation of either one, compares the first wireless link status with the second wireless link status and provides guidance for resolving a communication problem based on the comparison. The latency of the communicating medical devices is considered.

26. 发明申请

US20170049954A1 APPARATUS AND METHODS FOR SELF-ADMINISTRATION OF VACCINES AND OTHER MEDICAMENTS 审中-公开
标题翻译：疫苗和其他药物自我管理的装置和方法
公开(公告)号：US20170049954A1
公开(公告)日：2017-02-23
申请号：US15343452
申请日：2016-11-04
申请人： kaleo, Inc.
发明人： Eric S. EDWARDS , Evan T. EDWARDS , Mark J. LICATA , Paul F. MEYERS , David A. WEINZIERL
IPC分类号： A61M5/00 , A61M5/24 , A61M5/20
CPC分类号： A61M5/2033 , A61M5/002 , A61M5/19 , A61M5/2053 , A61M5/24 , A61M5/2448 , A61M5/3129 , A61M5/31525 , A61M5/3202 , A61M5/3204 , A61M5/326 , A61M5/5086 , A61M15/0025 , A61M15/008 , A61M15/0081 , A61M15/0083 , A61M15/009 , A61M2005/2013 , A61M2005/2026 , A61M2005/206 , A61M2205/13 , A61M2205/14 , A61M2205/18 , A61M2205/3317 , A61M2205/332 , A61M2205/3368 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3576 , A61M2205/3592 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/6018 , A61M2205/6036 , A61M2205/8206 , A61M2209/01 , A61M2209/086 , G06F19/00 , G06F19/3468 , Y02A90/22 , Y02A90/26
摘要： A medicament delivery device includes a housing, a medicament container disposed within the housing, an activation mechanism, a cover and an electronic circuit system. The activation mechanism includes an energy storage member configured to produce a force to deliver the dose of a medicament and/or vaccine. The cover is configured to receive at least a portion of the housing. The electronic circuit system is coupled to the housing such that a protrusion of the cover electrically isolates a battery from a portion of the electronic circuit system when the portion of the housing is received by the cover. The electronic circuit system is configured to be electrically coupled to the battery and to produce a recorded speech output when the portion of the housing is at least partially removed from the cover. The electronic circuit system configured to produce a signal when the activation mechanism is actuated.
摘要翻译：药物输送装置包括壳体，设置在壳体内的药物容器，激活机构，盖子和电子电路系统。激活机构包括被配置为产生递送药物和/或疫苗的剂量的力的能量存储构件。盖构造成容纳壳体的至少一部分。电子电路系统耦合到壳体，使得当壳体的部分被盖接收时，盖的突起将电池与电子电路系统的一部分电隔离。电子电路系统被配置为电耦合到电池并且当壳体的该部分至少部分地从盖上移除时产生记录的语音输出。所述电子电路系统被配置为当所述启动机构被致动时产生信号。

27. 发明授权

US09572939B2 Piston for a cartridge for use in a drug delivery device 有权
标题翻译：用于药物输送装置的药筒的活塞
公开(公告)号：US09572939B2
公开(公告)日：2017-02-21
申请号：US14355617
申请日：2012-11-01
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Ramatullah Qurishi , Martin Otten , Stefan Trinkle , Jörn Möckel , Sebastian Thiel
IPC分类号： A61M5/315 , A61M5/31
CPC分类号： A61M5/31511 , A61M5/281 , A61M5/3129 , A61M5/315 , A61M5/31513 , A61M2005/31516 , A61M2205/3306 , A61M2205/3368 , A61M2205/3569 , A61M2205/3576 , A61M2205/60 , A61M2205/6054 , A61M2207/10
摘要： The present invention relates to a piston for a cartridge to be filled with a medicament, the piston comprising: a first piston member comprising a first material and forming a distal end face of the piston, a second piston member comprising a second material of lower compressibility compared to the first material, wherein the second piston member is arranged in a cupped receptacle of the first piston member and provides a thrust receiving surface at a proximal end of the piston.
摘要翻译：本发明涉及一种用于填充药物的药筒的活塞，活塞包括：第一活塞构件，包括第一材料并形成活塞的远端面;第二活塞构件，包括具有较低压缩性的第二材料与第一材料相比，其中第二活塞构件布置在第一活塞构件的杯形容器中并且在活塞的近端处提供止推接收表面。

28. 发明申请

US20160367185A1 Closed Loop Control System Based On A Non-Invasive Continuous Sensor 审中-公开
标题翻译：基于非侵入式连续传感器的闭环控制系统
公开(公告)号：US20160367185A1
公开(公告)日：2016-12-22
申请号：US15251900
申请日：2016-08-30
申请人： Verily Life Sciences LLC
发明人： Huanfen Yao
IPC分类号： A61B5/00 , A61M5/142 , A61B5/1477 , A61B5/145 , A61M5/172
CPC分类号： A61B5/4836 , A61B5/002 , A61B5/0022 , A61B5/14507 , A61B5/14532 , A61B5/1477 , A61B5/4839 , A61B5/6821 , A61B5/742 , A61B2010/0067 , A61B2560/0214 , A61B2562/028 , A61M5/142 , A61M5/14244 , A61M5/1723 , A61M2205/3317 , A61M2205/3561 , A61M2205/3576 , A61M2205/3584 , A61M2205/3592 , A61M2205/6054 , A61M2210/0612 , A61M2230/005 , A61M2230/201 , G02C7/04
摘要： Methods and systems for controlling analyte levels are described. An example method may include receiving a sensor measurement relating to an eye-mountable device. The method also may include determining an analyte concentration based on the one or more sensor measurements, and comparing the analyte concentration to a target analyte concentration. Based on the comparing, the method further may include providing instructions to a drug delivery device, where the instructions are configured to control a drug delivery rate by the drug delivery device.
摘要翻译：描述了用于控制分析物水平的方法和系统。示例性方法可以包括接收与眼睛可安装装置有关的传感器测量。该方法还可以包括基于一个或多个传感器测量确定分析物浓度，并将分析物浓度与目标分析物浓度进行比较。基于比较，该方法还可以包括向药物递送装置提供指令，其中指令被配置为通过药物递送装置控制药物递送速率。

29. 发明申请

US20160346469A1 DISPOSABLE INFUSION FLUID DELIVERY DEVICE FOR PROGRAMMABLE LARGE VOLUME DRUG DELIVERY 审中-公开
标题翻译：用于可编程大容量药物输送的可替换的输注液体输送装置
公开(公告)号：US20160346469A1
公开(公告)日：2016-12-01
申请号：US15164277
申请日：2016-05-25
申请人： Hospira, Inc.
发明人： Gary David Shubinsky , Thomas D. Johnson , Jeffrey Donald Merwin , Vlad Radu Balteanu
IPC分类号： A61M5/172 , A61M5/142
CPC分类号： A61M5/172 , A61M5/142 , A61M2205/3331 , A61M2205/3368 , A61M2205/3576 , A61M2205/50 , A61M2205/52 , A61M2205/6054 , A61M2205/6072 , G06F19/3468
摘要： A disposable electronically controlled infusion pump system includes at least one disposable infusion container and at least one disposable electronically controlled medication pumping system. The at least one disposable infusion container is configured to contain infusion fluid. The at least one disposable electronically controlled medication pumping system is fluidly connected to the at least one disposable infusion container. The disposable electronically controlled medication pumping system includes an infusion channel, a disposable electronically controlled micropump, and valves, but may further include a microprocessor, a memory, a battery or power receiver configured to wirelessly receive power, a wireless communication device, and other components. The memory is in electronic communication with the microprocessor. The wireless communication device is configured to receive a wireless signal which wirelessly controls the disposable electronically controlled medication pumping system. The disposable electronically controlled micropump is configured to pump the infusion fluid through the infusion channel. The valves are connected to the infusion channel.
摘要翻译：一次性电子控制输注泵系统包括至少一个一次性输注容器和至少一个一次性电子控制的药物泵送系统。所述至少一个一次性输注容器构造成容纳输注液。所述至少一个一次性电子控制药物泵送系统流体地连接到所述至少一个一次性输注容器。一次性电子控制的药物泵送系统包括输注通道，一次性电子控制的微型泵和阀，但是还可以包括微处理器，存储器，配置成无线接收电力的电池或电源接收器，无线通信设备和其他组件。存储器与微处理器进行电子通信。无线通信设备被配置为接收无线控制一次性电子控制的药物泵送系统的无线信号。一次性电子控制的微量泵构造成将输注流体泵送通过输注通道。阀门连接到输液通道。

30. 发明申请

US20160339177A1 AUTOMATIC INSULIN DELIVERY SYSTEM 审中-公开
标题翻译：自动胰岛素输送系统
公开(公告)号：US20160339177A1
公开(公告)日：2016-11-24
申请号：US15137519
申请日：2016-04-25
申请人： IOWA STATE UNIVERSITY RESEARCH FOUNDATION,INC.
发明人： Derrick K. Rollins, SR.
IPC分类号： A61M5/172 , G06F19/00 , A61K38/28
CPC分类号： A61M5/1723 , A61K38/28 , A61M2205/3303 , A61M2205/3576 , A61M2205/50 , G06F19/00 , G06F19/3468 , G16H20/17
摘要： A system and method for automatically administering insulin based on a feedforward control. The automatic insulin delivery system may include a computing device comprising a processor, machine readable non-transitory media which stores the coupled-model of the invention, and a monitoring system. The machine readable transitory media may be configured to receive one or more inputs and the coupled-model may utilize a feedforward control to parameterize the inputs and generate an output that can be translated to a type and amount of insulin to be administered by the system. The input(s) received by the machine readable non-transitory media may be created by a user or received from one or more sensors. The method may include providing a model that is stored on a machine readable non-transitory media and administering insulin based on the output provided by the model.
摘要翻译：一种基于前馈控制自动管理胰岛素的系统和方法。自动胰岛素递送系统可以包括计算设备，其包括处理器，存储本发明的耦合模型的机器可读非中介媒体和监视系统。机器可读暂时性介质可以被配置为接收一个或多个输入，并且耦合模型可以利用前馈控制来参数化输入并产生可以被转换为由系统管理的胰岛素的类型和量的输出。由机器可读的非暂时介质接收的输入可由用户创建或从一个或多个传感器接收。该方法可以包括提供存储在机器可读的非暂时介质上并基于由模型提供的输出来管理胰岛素的模型。

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