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21. 发明授权

US5656754A Process for preparing cephem compounds 失效
标题翻译：头孢烯化合物的制备方法
公开(公告)号：US5656754A
公开(公告)日：1997-08-12
申请号：US211119
申请日：1994-03-22
申请人： Shigeru Torii , Hideo Tanaka , Michio Sasaoka , Takashi Shiroi , Yutaka Kameyama
发明人： Shigeru Torii , Hideo Tanaka , Michio Sasaoka , Takashi Shiroi , Yutaka Kameyama
IPC分类号： B01J27/122 , C07B61/00 , C07D205/08 , C07D205/09 , C07D205/095 , C07D501/00 , C07D501/08 , C07D501/18 , C07D501/22 , C07D501/16
CPC分类号： C07D205/09 , C07D205/095 , C07D501/00 , Y02P20/55
摘要： The present invention provides a process for preparing a cephem compound represented by the general formula (3) characterized in that an allenyl-.beta.-lactam compound represented by the general formula (1) is reacted with an organotin compound represented by the general formula (2) in the presence of a monovalent copper salt ##STR1## wherein R.sup.1 is a hydrogen atom, halogen atom, amino or protected amino, R.sup.2 is a hydrogen atom, halogen atom, lower alkoxyl, lower acyl, lower alkyl, lower alkyl having hydroxyl or protected hydroxyl as a substituent, hydroxyl or protected hydroxyl, or R.sup.1 and R.sup.2 form=0 when taken together, R.sup.3 is a hydrogen atom or carboxylic acid protecting group, R.sup.4 is aryl, aryl having a substituent, nitrogen-containing aromatic heterocyclic group or nitrogen-containing aromatic heterocyclic group having a substituent, and m is 0 or 2,(R.sup.5).sub.n --Sn(R.sup.6).sub.4--n (2)wherein R.sup.5 is alkenyl, alkenyl having a substituent, aryl, aryl having a substituent, nitrogen-containing aromatic heterocyclic group or nitrogen-containing aromatic heterocyclic group having a substituent, R.sup.6 is lower alkyl, and n is 1 or 2, ##STR2## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.5 are the same as defined above.
摘要翻译： PCT No.PCT / JP93 / 01041 Sec。 371日期：1994年3月22日 102（e）1994年3月22日PCT 1993年7月26日PCT公布。出版物WO94 / 02490 日期：1994年2月3日本发明提供一种制备由通式（3）表示的头孢烯化合物的方法，其特征在于，将由通式（1）表示的丙烯酰基-β-内酰胺化合物与由在一价铜盐（1）的存在下通式（2）其中R1是氢原子，卤素原子，氨基或被保护的氨基，R2是氢原子，卤素原子，低级烷氧基，低级酰基，低级烷基，具有羟基或被保护的羟基作为取代基的低级烷基，羟基或保护的羟基，或者R 1和R 2形成= 0，当R 3是氢原子或羧酸保护基时，R 4是芳基，具有取代基的芳基，具有取代基的含氮芳香族杂环基或含氮芳香族杂环基，m为0或2，（R5）n-Sn（R6）4-n（2）其中R5为烯基，具有取代基的烯基，，具有取代基的芳基，氮 - 具有取代基的芳族杂环基或含氮芳族杂环基，R6是低级烷基，n是1或2，其中R1，R2，R3和R5与上述定义相同。

22. 发明授权

US5464833A Apoptosis regulating composition 失效
标题翻译：凋亡调节组成
公开(公告)号：US5464833A
公开(公告)日：1995-11-07
申请号：US211818
申请日：1994-04-19
申请人： Satoru Nakai , Koutoku Aihara , Hideo Tanaka , Hitomi Iba , Kazuyoshi Kawai , Hiroyuki Ichikawa , Seiji Akamatsu , Fumio Saito , Michiaki Tominaga , Masakazu Adachi
发明人： Satoru Nakai , Koutoku Aihara , Hideo Tanaka , Hitomi Iba , Kazuyoshi Kawai , Hiroyuki Ichikawa , Seiji Akamatsu , Fumio Saito , Michiaki Tominaga , Masakazu Adachi
IPC分类号： C07D215/22 , C07D215/227 , C07D215/38 , A61K31/495
CPC分类号： C07D215/227 , C07D215/38
摘要： Apoptosis regulating compositions each comprising a member selected from a series of carbostyril derivatives and salts thereof, inclusive of carbostyril derivatives of general formula (1) ##STR1## and salts thereof, as an active ingredient are provided. The apoptosis regulating compositions of the invention are of use as anticancer agents, antiretrovirus agents, therapeutic agents for autoimmune diseases, therapeutic agents for thrombocytopenia, therapeutic agents for Alzheimer's disease, therapeutic agents for diseases of the liver, and cancer metastasis inhibitors, among others.
摘要翻译： PCT No.PCT / JP93 / 01144 Sec。 371日期1994年04月19日 102（e）1994年4月19日PCT PCT 1993年8月12日PCT公布。出版物WO94 / 04504 日本3月3日，1994.各种调节组合物各自包含选自一系列喹诺酮衍生物及其盐的成员，包括通式（1）的喹诺酮衍生物及其盐作为活性成分。提供。本发明的凋亡调节组合物可用作抗癌剂，抗逆转录病毒剂，自身免疫性疾病的治疗剂，血小板减少症的治疗剂，阿尔茨海默病的治疗剂，肝脏疾病的治疗剂和癌症转移抑制剂等。

23. 发明授权

US5377465A Ultra-high multi-story buildings and construction thereof 失效
标题翻译：超高层多层建筑及其建筑
公开(公告)号：US5377465A
公开(公告)日：1995-01-03
申请号：US820887
申请日：1992-03-18
申请人： Takuji Kobori , Shigeru Ban , Toshihiko Kubota , Osamu Nohira , Norihide Koshika , Koji Kondo , Sadaaki Masuda , Yoshinori Kitamura , Hideo Tanaka , Hiroomi Sato , A. Scott Howe
发明人： Takuji Kobori , Shigeru Ban , Toshihiko Kubota , Osamu Nohira , Norihide Koshika , Koji Kondo , Sadaaki Masuda , Yoshinori Kitamura , Hideo Tanaka , Hiroomi Sato , A. Scott Howe
IPC分类号： E04B1/34 , E04H1/00
CPC分类号： E04B1/3404
摘要： An extra super multi-story building having one piece of extra super multi-story of about 200 story construction, two pieces of extra super multi-stories of about 150 story construction and one piece of extra super multi-story of about 100 story construction. Each extra super multi-story includes two through four pieces of tower-like super multi-stories of about 50 story construction and of about 50 m in diameter (floor area: about 200 m.sup.2 /story). A sky lobby is provided about every 50 stories connecting the extra super multi-stories. Four shuttle elevators lead from the ground to the sky lobbies, and a sightseeing tower and high-rise garden (sky dome) are provided at the rooftop of the extra super multi-story building. Main facilities such as offices, hotels and residences are arranged in each extra multi-story. In addition, in order to be able to construct the extra super multi-story building, the individual extra super multi-story buildings are monolithically connected with one another by girders every several ten stories, and a space truss is constructed on the outside of each extra super multi-story building.
摘要翻译： PCT No.PCT / JP91 / 00341 Sec。 371日期：1992年3月18日 102（e）1992年3月18日PCT 1991年3月13日PCT公布。 WO91 / 18161 PCT出版物日期：1991年11月28日。超级多层建筑有超过200层的超级多层建筑，超过150层的超级多层次的超级多层建筑，大概100层建筑故事。每个额外的超级多层楼包括大约50层建筑和直径约50米（占地面积：约200平方米/层）的两层至四层塔式超级多层楼。每隔50层提供一个天空大厅，连接超级多层次的超级故事。四座穿梭电梯从地面到天空大堂，另外还有超级多层建筑的屋顶设有观光塔和高层花园（天空圆顶）。主要设施如办公室，酒店和住宅都安排在每个额外的多层次。另外，为了能够构建超级多层建筑，个别的超级多层建筑每隔十层就通过大梁相互整体连接起来，并在每个楼层的外面建造一个空间桁架超级多层建筑。

24. 发明授权

US5362033A Hot plate for keeping molten metal in a molten state 失效
标题翻译：用于将熔融金属保持在熔融状态的热板
公开(公告)号：US5362033A
公开(公告)日：1994-11-08
申请号：US141100
申请日：1993-10-26
申请人： Seiji Sakurai , Junichi Kuchiki , Hideo Tanaka , Syoichi Naruse , Shigeru Fukumaru
发明人： Seiji Sakurai , Junichi Kuchiki , Hideo Tanaka , Syoichi Naruse , Shigeru Fukumaru
IPC分类号： B22D41/01 , F27B3/20 , F27D99/00 , H05B3/62 , C22B7/00
CPC分类号： H05B3/62 , B22D41/01 , F27B3/20 , F27D2099/0013
摘要： A hot plate is used with a molten metal storage container in which a molten metal or bath is temporarily stored prior to any subsequent casting process, and keeps the molten metal temporarily stored in the storage container at a specific constant temperature by heating the molten metal as required. The temperature of the stored molten metal is controlled so that it cannot fall below the particular temperature.The hot plate includes a heating unit formed in a flat shape from any suitable heat resistant, electrically insulating material and having an electric heating wire or coil therein: and A box unit made of any suitable ceramic material has the flat heating unit freely inserted and removably mounted therein.As a variation of the hot plate, the box unit may include a ceramic coating layer formed on the outer peripheral surface thereof, the ceramic coating layer being reinforced with any suitable fibrous ceramic textile.Leads from the electric heating wire or coil may be drawn through the lateral side of the box unit near an upper open side at the top of the box unit.
摘要翻译：一个热板与熔融金属储存容器一起使用，其中熔融金属或浴液在任何后续的铸造过程之前临时储存，并通过加热熔融金属将熔融金属临时储存在特定的恒定温度下需要。控制储存的熔融金属的温度使其不能低于特定温度。热板包括由任何合适的耐热电绝缘材料形成为扁平形状的加热单元，并且在其中具有电加热丝或线圈。由任何合适的陶瓷材料制成的盒形单元具有自由插入和可拆卸的扁平加热单元安装在其中。作为热板的变型，盒单元可以包括在其外周表面上形成的陶瓷涂层，陶瓷涂层由任何合适的纤维陶瓷织物增强。来自电加热线或线圈的引线可以通过盒单元的侧面靠近盒单元顶部的上开口侧。

25. 发明授权

US5126447A Process for preparation of .beta.-lactam derivative from an alkenyl substituted .beta.-lactam derivative using a ruthenium or rhenium catalyst and a periodic acid 失效
标题翻译：使用钌或铑催化剂和周期酸从碱性取代（BETA）-LACTAM衍生物衍生得到的（BETA）-LACTAM衍生物的方法
公开(公告)号：US5126447A
公开(公告)日：1992-06-30
申请号：US662605
申请日：1991-03-01
申请人： Sigeru Torii , Hideo Tanaka , Masatoshi Taniguchi , Michio Sasaoka , Takashi Shiroi , Ryo Kikuchi , Yutaka Kameyama
发明人： Sigeru Torii , Hideo Tanaka , Masatoshi Taniguchi , Michio Sasaoka , Takashi Shiroi , Ryo Kikuchi , Yutaka Kameyama
IPC分类号： B01J23/36 , B01J23/46 , C01B11/22 , C07B61/00 , C07D205/085 , C07D205/095 , C07D403/04 , C07D405/14 , C07F7/18
CPC分类号： C07D403/04 , C07D205/085 , C07D205/095 , C07D405/14 , C07F7/186 , Y02P20/55
摘要： A process for preparing a .beta.-lactam derivative of formula (2) and/or the corresponding enol tautomer, which includes oxidizing an alkenyl-substituted .beta.-lactam derivative of formula (1) in the presence of a ruthenium catalyst or a rhenium catalyst using a periodic acid: ##STR1## wherein R.sup.1 is a hydrogen atom, a C.sub.1-4 alkyl group or a C.sub.1-4 haloalkyl group, R.sup.2 is a hydrogen atom, a C.sub.1-4 alkyl group or a phenyl group which may have a substituent, A is a group selected from ##STR2## wherein R.sup.3 is an amino group or a protected amino group, and R.sup.4 -R.sup.8 are as defined in the application.

26. 发明授权

US5056004A Program control system which simultaneously executes a program to be repeated and decrements repetition numbers 失效
标题翻译：程序控制系统，同时执行要重复的程序和拒绝代码编号
公开(公告)号：US5056004A
公开(公告)日：1991-10-08
申请号：US258082
申请日：1988-10-14
申请人： Yuko Ohde , Hideo Tanaka , Ichiro Kuroda
发明人： Yuko Ohde , Hideo Tanaka , Ichiro Kuroda
IPC分类号： G06F9/32
CPC分类号： G06F9/325
摘要： A for controlling a includes circuit a register for holding the repetition number of a program operation to be repeated, a counter receiving the content of the register and adapted to decrement in response with each execution of the program operation to be repeated, a memory for storing a sequence of instructions, and a controller for receiving an instruction read from the memory modification in a normal condition and to convert the received instruction into a no-operation instruction when the content of the counter becomes a predetermined content.
摘要翻译：用于控制的A包括电路，用于保持要重复的编程操作的重复次数的寄存器，接收所述寄存器的内容的计数器，并适于响应于每次执行要重复的程序操作而递减;存储器，用于存储指令序列，以及控制器，用于在正常状态下接收从存储器修改读取的指令，并且当计数器的内容成为预定内容时，将接收到的指令转换为无操作指令。

27. 发明授权

US5037740A Novel immobilized cells and fermentation method utilizing the same 失效
标题翻译：新型固定化细胞和利用其的发酵方法
公开(公告)号：US5037740A
公开(公告)日：1991-08-06
申请号：US748597
申请日：1985-06-25
申请人： Hideo Tanaka , Hiroshi Kurosawa , Mizuo Yajima
发明人： Hideo Tanaka , Hiroshi Kurosawa , Mizuo Yajima
IPC分类号： C12N11/02 , C12N11/04 , C12P1/00 , C12P7/06 , C12P7/14 , C12P7/56 , C12P39/00
CPC分类号： C12P7/56 , C12N11/04 , C12P39/00 , C12P7/14 , Y02E50/17
摘要： Novel immobilized cells are prepared by immobilizing cells of at least one aerobic microorganism and cells of at least one anaerobic microorganism in a single gel immobilizing carrier. The immobilized cells are utilized in a fermentation method. Many useful fermentation products can be readily and economically obtained by using the immobilized cells which accommodate both aerobic and anaerobic metabolic function simultaneously.
摘要翻译：通过将至少一种需氧微生物的细胞和至少一种厌氧微生物的细胞固定在单一凝胶固定载体中来制备新的固定化细胞。固定化细胞用于发酵方法。通过使用同时适应有氧和厌氧代谢功能的固定化细胞，可以容易地和经济地获得许多有用的发酵产物。

28. 发明授权

US4961109A Chargeable program receiving limit setting system in two-way cable television system 失效
标题翻译：双向有线电视系统收费限额设定系统
公开(公告)号：US4961109A
公开(公告)日：1990-10-02
申请号：US372154
申请日：1989-06-27
申请人： Hideo Tanaka
发明人： Hideo Tanaka
IPC分类号： G06F21/10 , G06F21/24 , H04H9/00 , H04H20/76 , H04H20/79 , H04H60/15 , H04H60/21 , H04H60/31 , H04N7/16 , H04N7/173
CPC分类号： H04H60/15 , H04H20/76 , H04H20/79 , H04H60/21 , H04H60/31 , H04N7/165 , H04N7/17309 , H04N2007/1739
摘要： A CATV television system in which a subscriber can only charge a maximum number of events before the central facility polls the subscriber's terminal unit for charged events. The subscriber's terminal contains a credit limit register which contains the maximum number of chargeable events. The central facility can change the individual subscriber's credit limit register, dependent on credit worthiness, by a command sent over the CATV lines.
摘要翻译：一种CATV电视系统，其中用户只能在中央设施轮询用户的终端单元以进行充电事件之前仅收取最大数量的事件。订户的终端包含一个信用限额寄存器，其中包含最多可收费事件数。中央设施可以通过CATV线路发送的命令来更改个人用户的信用限额寄存器，取决于信用额度。

29. 发明授权

US4853468A Process for the preparation of cephem derivatives 失效
标题翻译：头孢烯衍生物的制备方法
公开(公告)号：US4853468A
公开(公告)日：1989-08-01
申请号：US166918
申请日：1988-03-11
申请人： Sigeru Torii , Kenji Uneyama , Hideo Tanaka , Junzo Nokami , Michio Sasaoka , Norio Saito , Takashi Shiroi
发明人： Sigeru Torii , Kenji Uneyama , Hideo Tanaka , Junzo Nokami , Michio Sasaoka , Norio Saito , Takashi Shiroi
IPC分类号： C07D205/095 , C07D403/12 , C07D501/02 , C07D501/08 , C07F9/568
CPC分类号： C07D403/12 , C07D205/095 , C07F9/568
摘要： This invention provides azetidinone derivatives represented by the formula ##STR1## and processes for preparing the same. The azetidinone derivatives are used as the intermediates for producing cephalosporin compounds useful as antibiotic agents.
摘要翻译：本发明提供由式“IMAGE”表示的氮杂环丁酮衍生物及其制备方法。氮杂环丁酮衍生物用作生产用作抗生素剂的头孢菌素化合物的中间体。

30. 发明授权

US4784734A Azetidinone derivatives and process for the preparation of the same 失效
标题翻译：氮杂环丁酮衍生物及其制备方法相同
公开(公告)号：US4784734A
公开(公告)日：1988-11-15
申请号：US71664
申请日：1987-07-09
申请人： Sigeru Torii , Kenji Uneyama , Hideo Tanaka , Junzo Nokami , Michio Sasaoka , Norio Saito , Takashi Shiroi
发明人： Sigeru Torii , Kenji Uneyama , Hideo Tanaka , Junzo Nokami , Michio Sasaoka , Norio Saito , Takashi Shiroi
IPC分类号： C07D205/095 , C07D403/12 , C07F9/568 , C25B3/06
CPC分类号： C07D403/12 , C07D205/095 , C07F9/568
摘要： This invention provides azetidinone derivatives represented by the formula ##STR1## and processes for preparing the same. The azetidinone derivatives are used as the intermediates for producing cephalosporin compounds useful as antibiotic agents.
摘要翻译：本发明提供由式“IMAGE”表示的氮杂环丁酮衍生物及其制备方法。氮杂环丁酮衍生物用作生产用作抗生素剂的头孢菌素化合物的中间体。

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