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21. 发明授权

US5803441A Damper mechanism with undulated ribbon-like spring having means for restricting radial movement of the spring 失效
标题翻译：具有波纹带状弹簧的阻尼机构具有用于限制弹簧的径向移动的装置
公开(公告)号：US5803441A
公开(公告)日：1998-09-08
申请号：US631197
申请日：1996-04-12
申请人： Kozo Yamamoto
发明人： Kozo Yamamoto
IPC分类号： F16F1/02 , F16F15/133 , F16D3/12 , F16D3/80
CPC分类号： F16F1/025 , F16F15/1335
摘要： To reduce a frictional resistance generated between undulated ribbon-like springs and outer circumferential walls, a flywheel assembly is composed of a first flywheel 1, a second flywheel 3 and ribbon-like springs 18. A fluid chamber 17 is formed between the second flywheel 3 and the first flywheel 1. The undulated ribbon-like spring 18 is disposed within the fluid chamber 17. In one embodiment, a projecting ring portion 20a that projects beyond the other ring portions 20 is provided so as to contact with an outer circumferential portion 7a of the fluid chamber 17 in order to prevent the remainder of the spring from contacting the portion 7a of the chamber 17. In another embodiment, a mid-portion of the undulated ribbon-like spring is confined to restrict radially outward movement by a plate and axially aligned pins which prevent radial movement of portions of the spring.
摘要翻译：为了减少波状带状弹簧和外周壁之间产生的摩擦阻力，飞轮组件由第一飞轮1，第二飞轮3和带状弹簧18组成。流体室17形成在第二飞轮3 和第一飞轮1.布置的带状弹簧18设置在流体室17内。在一个实施例中，突出超过其它环部20的突出环部分20a设置成与外周部分7a 以防止弹簧的其余部分接触腔室17的部分7a。在另一个实施例中，波纹带状弹簧的中部被限制以通过板限制径向向外运动，并且轴向对齐的销，其防止弹簧的部分的径向移动。

22. 发明授权

US5731193A Recombinant DNA and transformant containing the same 失效
标题翻译：重组DNA和含有其的转化体
公开(公告)号：US5731193A
公开(公告)日：1998-03-24
申请号：US828511
申请日：1997-03-31
申请人： Tetsuya Mori , Kozo Yamamoto , Tsunetaka Ohta
发明人： Tetsuya Mori , Kozo Yamamoto , Tsunetaka Ohta
IPC分类号： C12N15/09 , C07K14/505 , C07K14/56 , C12N5/10 , C12N15/85 , C07H21/04 , C12N15/67 , C12P21/02
CPC分类号： C12N15/85 , C07K14/505 , C07K14/56 , C12N2830/00 , C12N2830/42 , C12N2830/85
摘要： Insertion of IFN-alpha promoters in recombinant DNAs improves their expression efficiencies for useful polypeptides. Expression of such a recombinant DNA in host cells of mammalian origin is artificially controllable by the presence and absence of external stimuli using IFN-alpha inducers. Thus, transformants with such a recombinant DNA readily increase to a maximized cell density with causing neither damages nor extinction due to polypeptides they produce, and subsequent exposure to IFN-alpha inducers allows the proliferated cells to efficiently produce polypeptides with significant glycosylations.
摘要翻译：在重组DNA中插入IFN-α启动子改善了其对有用多肽的表达效率。这种重组DNA在哺乳动物来源的宿主细胞中的表达可以通过使用IFN-α诱导物的外部刺激的存在和不存在来人为可控。因此，具有这种重组DNA的转化体容易增加到最大化的细胞密度，由于它们产生的多肽而不造成损伤或消灭，随后暴露于IFN-α诱导物允许增殖的细胞有效地产生具有显着糖基化的多肽。

23. 发明授权

US5401106A Bearing assembly with inner race bearing support means 失效
标题翻译：带内圈轴承支承装置的轴承总成
公开(公告)号：US5401106A
公开(公告)日：1995-03-28
申请号：US18708
申请日：1993-02-17
申请人： Kozo Yamamoto
发明人： Kozo Yamamoto
IPC分类号： F16C33/78 , F16C35/063 , F16F15/12 , F16F15/131 , F16F15/134 , F16F15/16 , F16F15/30
CPC分类号： F16F15/13171 , F16C33/7843 , F16C19/06 , F16C2361/55
摘要： The invention includes a bearing assembly having concentric inner and outer races and roller elements disposed therebetween. Seal members are disposed on either side of the races, flanking the roller elements. The outer race is provided with circumferential grooves adjacent to each axial face of the outer race. Annular urging members are fitted between the races, adjoining the seal members on the outer sides thereof, urging the seals into contact with the races. The outer circumferential edge of each urging member extends into one of the grooves in the outer race. The urging members are biased such that the inner circumferential edge of each engages the adjacent seal and retains the inner race within the outer race in order to reduce wobble and vibration between the inner and outer races.
摘要翻译：本发明包括具有同心的内圈和外圈以及设置在它们之间的辊元件的轴承组件。密封构件设置在赛车的两侧，侧面是滚子元件。外圈设有与外圈的每个轴向面相邻的圆周槽。环形推动构件安装在邻接其外侧上的密封构件的种族之间，迫使密封件与种族接触。每个推动构件的外周缘延伸到外圈中的一个凹槽中。推动构件被偏置，使得每个的内周边缘接合相邻的密封件并且将内座圈保持在外座圈内，以便减少内座圈和外座圈之间的摆动和振动。

24. 发明授权

US4006764A Protection case for tape-recorder or radio-set 失效
标题翻译：录音机或无线电设备保护箱
公开(公告)号：US4006764A
公开(公告)日：1977-02-08
申请号：US513134
申请日：1974-10-08
申请人： Kozo Yamamoto , Takuro Ibi
发明人： Kozo Yamamoto , Takuro Ibi
IPC分类号： B65D85/00 , B65D85/30 , B65D65/06
CPC分类号： B65D85/30 , B65D85/00
摘要： This invention relates to protection cases for such portable sonance instruments as tape recorders, radio receiving sets, etc. These cases are made with waterproof sheet material such as vinyl chloride, so as to cover tightly to protect those instruments from water, spray, dust or the like.
摘要翻译：本发明涉及用于诸如录音机，无线电收发机等的便携式声学仪器的保护箱。这些情况是用诸如氯乙烯的防水片材制成的，以便紧密地覆盖以保护这些仪器免受水，喷雾，灰尘或类似。

25. 发明申请

US20140034436A1 LOCK-UP DEVICE FOR TORQUE CONVERTER 有权
标题翻译：用于转矩转换器的锁定装置
公开(公告)号：US20140034436A1
公开(公告)日：2014-02-06
申请号：US14111113
申请日：2012-04-17
申请人： Tatsuyuki Aoki , Kozo Yamamoto , Ken Motosune , Yoshihiro Matsuoka
发明人： Tatsuyuki Aoki , Kozo Yamamoto , Ken Motosune , Yoshihiro Matsuoka
IPC分类号： F16H45/02
CPC分类号： F16H45/02 , F16D13/58 , F16D25/12 , F16H2045/007 , F16H2045/021 , F16H2045/0284 , F16H2045/0294
摘要： A lock-up device is a device disposed in a space produced between a front cover and a turbine in a torque converter so as to mechanically connect the front cover and the turbine, and includes a clutch part and a release part. The clutch part is disposed in a power transmission path from the front cover to the turbine, and is configured to be in a clutch-on state of transmitting a power from the front cover to the turbine in a set posture. The release part is configured to be actuated by means of a hydraulic pressure, turn the clutch part of the clutch-on state into a clutch-off state, and block transmission of the power from the front cover to the turbine.
摘要翻译：锁定装置是在变矩器中设置在前盖和涡轮之间产生的空间中的装置，以便机械地连接前盖和涡轮机，并且包括离合器部分和释放部件。离合器部分设置在从前盖到涡轮机的动力传递路径中，并且被构造成处于以设定姿势从前盖向涡轮机传递动力的离合器打开状态。释放部被构造成通过液压被致动，将离合器接通状态的离合器部分转换成离合器关闭状态，并且阻止从前盖向涡轮机传递动力。

26. 发明授权

US07445552B2 Dual-mass flywheel 失效
标题翻译：双质量飞轮
公开(公告)号：US07445552B2
公开(公告)日：2008-11-04
申请号：US10897030
申请日：2004-07-23
申请人： Kozo Yamamoto , Hiroyoshi Tsuruta
发明人： Kozo Yamamoto , Hiroyoshi Tsuruta
IPC分类号： F16F15/121 , F16D13/68
CPC分类号： F16C19/46 , F16C33/605 , F16C33/76 , F16C33/7809 , F16C2361/55 , F16F15/13171
摘要： A flywheel assembly with an improved bearing structure is provided. The flywheel damper (11) is a flywheel assembly for transmitting torque from the crankshaft of an engine, and has a first flywheel assembly (4), a second flywheel assembly (5), a damper mechanism (6), and a needle bearing (43). The first flywheel assembly (4) is fixed to the crankshaft (2). The second flywheel assembly (5) is disposed so as to be able to rotate relative to the first flywheel assembly (4). The damper mechanism (6) elastically connects the second flywheel assembly (5) to the crankshaft (2) in the rotation direction. The needle bearing (43) is a bearing to support rotatably the second flywheel assembly (5) on the crankshaft (2), and has a plurality of needles (44) disposed between the peripheral surfaces (21d) and (37b) of both members.
摘要翻译：提供了具有改进的轴承结构的飞轮组件。飞轮阻尼器（11）是用于从发动机的曲轴传递扭矩的飞轮组件，并且具有第一飞轮组件（4），第二飞轮组件（5），阻尼机构（6）和滚针轴承 43）。第一飞轮组件（4）固定在曲轴（2）上。第二飞轮组件（5）被布置成能够相对于第一飞轮组件（4）旋转。阻尼器机构（6）沿着旋转方向将第二飞轮组件（5）弹性地连接到曲轴（2）。滚针轴承（43）是用于将第二飞轮组件（5）可旋转地支撑在曲轴（2）上的轴承，并且具有设置在外周表面（21d）和（37b）之间的多个针（44）两个成员。

27. 发明授权

US07037685B2 DNA encoding loypeptides having interferon-γ inducing activity 失效
标题翻译：编码具有干扰素-γ诱导活性的寡肽的DNA
公开(公告)号：US07037685B2
公开(公告)日：2006-05-02
申请号：US10260576
申请日：2002-10-01
申请人： Kozo Yamamoto , Iwao Okamoto , Masashi Kurimoto
发明人： Kozo Yamamoto , Iwao Okamoto , Masashi Kurimoto
IPC分类号： C12P21/02
CPC分类号： C07K14/54 , A61K38/00 , Y02A50/411
摘要： Disclosed are created stable polypeptides which are capable of inducing the production of interferon-gamma by immunocompetent cells. The present polypeptides contain specific amino acid sequences usually derived from the wild-type polypeptides, being capable of the production of interferon-gamma, by replacing the cysteine(s) with different amino acid(s). The present polypeptides possess a stability and an activity of inducing the production of IFN-γ by immunocompetent cells, both of which are significantly higher than those of the wild-type polypeptides. In addition to the activity, the present polypeptides can exhibit remarkable activities of inducing the formation of killer cells and enhancing thier cytotoxicities. The present polypeptides are easily obtainable by the process according to the present invention using recombinant DNA techniques. Thus the present polypeptides are useful for agents to treat and/or prevent susceptive diseases such as viral diseases, infections, malignant tumors, and immunopathies.
摘要翻译：公开了能够通过免疫活性细胞诱导干扰素-γ产生的稳定多肽。本发明的多肽含有通常衍生自野生型多肽的能够产生干扰素-γ的特异性氨基酸序列，通过用不同的氨基酸替代半胱氨酸。本发明的多肽具有通过免疫活性细胞诱导IFN-γ产生的稳定性和活性，两者均明显高于野生型多肽。除了活性之外，本发明的多肽可以表现出显着的诱导杀伤细胞形成的活性和增强其细胞毒性。本发明的多肽可以使用重组DNA技术通过本发明的方法容易地获得。因此，本发明的多肽可用于治疗和/或预防感染性疾病如病毒性疾病，感染，恶性肿瘤和免疫病症的药剂。

28. 发明授权

US06436396B1 Polypeptides having L-asparaginase activity 失效
公开(公告)号：US06436396B1
公开(公告)日：2002-08-20
申请号：US09634858
申请日：2000-08-08
申请人： Takeshi Ario , Madoka Taniai , Kozo Yamamoto , Masashi Kurimoto
发明人： Takeshi Ario , Madoka Taniai , Kozo Yamamoto , Masashi Kurimoto
IPC分类号： A61K3846
CPC分类号： C12N9/82 , A61K38/00
摘要： Disclosed are polypeptides which originate from mammal, having L-asparaginase activity. The polypeptides are easily prepared by applying recombinant DNA techniques to DNAs encoding the polypeptides and they exert satisfactory effects in the treatment and/or the prevention for diseases caused by tumor cells dependent on L-asparagine, and cause no substantial serious side effects even when administered to humans in relatively-high dose.

29. 发明授权

US06301995B1 Flywheel assembly and a torque converter 失效
标题翻译：飞轮组件和变矩器
公开(公告)号：US06301995B1
公开(公告)日：2001-10-16
申请号：US09607971
申请日：2000-06-30
申请人： Kozo Yamamoto
发明人： Kozo Yamamoto
IPC分类号： F16F1510
CPC分类号： F16F15/1201 , F16F7/104 , F16F15/1207 , F16F15/13107 , F16F15/13164 , F16H45/02 , Y10T29/49481 , Y10T74/2131
摘要： A flywheel assembly 1 includes a flywheel 2, a flexible plate 3 and a dynamic damper 4 to reduce the noise of an engine during acceleration of the speed of the engine. The flexible plate 3 connects the flywheel 2 with a crankshaft 5 so as to be able to oscillate in a bending direction. The dynamic damper 4 includes a mass body 13, and a plate 14 which connects the mass body 13 with the flywheel 2 so as to be able to oscillate in a bending direction.
摘要翻译：飞轮组件1包括飞轮2，柔性板3和动力减震器4，以在加速发动机速度期间减小发动机的噪音。柔性板3将飞轮2与曲轴5连接，以能够沿弯曲方向摆动。动力阻尼器4包括质量体13和将质量体13与飞轮2连接以能够沿弯曲方向摆动的板14。

30. 发明授权

US6140101A Polypeptides having L-asparaginase activity 失效
公开(公告)号：US6140101A
公开(公告)日：2000-10-31
申请号：US195666
申请日：1998-11-19
申请人： Takeshi Ario , Madoka Taniai , Kozo Yamamoto , Masashi Kurimoto
发明人： Takeshi Ario , Madoka Taniai , Kozo Yamamoto , Masashi Kurimoto
IPC分类号： A61K38/00 , C12N1/21 , C12N9/82 , C12N15/55 , C07H21/04 , C12N1/20 , C12N5/00
CPC分类号： C12N9/82 , A61K38/00
摘要： Disclosed are polypeptides which originate from mammal, having L-asparaginase activity. The polypeptides are easily prepared by applying recombinant DNA techniques to DNAs encoding the polypeptides and they exert satisfactory effects in the treatment and/or the prevention for diseases caused by tumor cells dependent on L-asparagine, and cause no substantial serious side effects even when administered to humans in relatively-high dose.

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