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21. 发明授权

US08178690B2 Compounds and methods for inhibiting the interaction of BCL proteins with binding partners 有权
标题翻译：抑制BCL蛋白与结合配偶体相互作用的化合物和方法
公开(公告)号：US08178690B2
公开(公告)日：2012-05-15
申请号：US13089530
申请日：2011-04-19
申请人： Alfredo C. Castro , Kristopher M. Depew , Michael J. Grogan , Charles W. Johannes , Edward B. Holson , Brian T. Hopkins , Gregg F. Keaney , Nii O. Koney , Tao Liu , David A. Mann , Marta Nevalainen , Stephane Peluso , Lawrence Blas Perez , Daniel A. Snyder , Thomas T. Tibbitts
发明人： Alfredo C. Castro , Kristopher M. Depew , Michael J. Grogan , Charles W. Johannes , Edward B. Holson , Brian T. Hopkins , Gregg F. Keaney , Nii O. Koney , Tao Liu , David A. Mann , Marta Nevalainen , Stephane Peluso , Lawrence Blas Perez , Daniel A. Snyder , Thomas T. Tibbitts
IPC分类号： C07D261/02 , A61K31/42
CPC分类号： C07D261/02 , A61K31/42 , A61K31/422 , A61K31/427 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/5377 , A61K45/06 , C07D413/10 , C07D413/12 , C07D417/12
摘要： The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.
摘要翻译：本发明涉及与bcl蛋白结合并抑制Bcl功能的含异唑烷的化合物。该化合物可用于治疗和调节与过度增生相关的疾病，例如癌症。

22. 发明申请

US20120026431A1 LIGHTGUIDE WITH OPTICAL FILM CONTAINING VOIDS AND BLACKLIGHT FOR DISPLAY SYSTEM 有权
标题翻译：具有光学薄膜的光束和显示系统的黑光
公开(公告)号：US20120026431A1
公开(公告)日：2012-02-02
申请号：US13264354
申请日：2010-04-14
申请人： William D. Coggio , John A. Wheatley , Tao Liu , Brian W. Ostlie , Encai Hao , William Blake Kolb , Qingbing Wang , Michael Benton Free , Brant U. Kolb , Michael L. Steiner , Scott M. Tapio
发明人： William D. Coggio , John A. Wheatley , Tao Liu , Brian W. Ostlie , Encai Hao , William Blake Kolb , Qingbing Wang , Michael Benton Free , Brant U. Kolb , Michael L. Steiner , Scott M. Tapio
IPC分类号： G02F1/13357 , F21V7/04 , F21V9/14 , F21V8/00
CPC分类号： G02B6/0051 , G02B5/02 , G02B6/0056 , G02B2207/107
摘要： A lightguide (3690) is disclosed. The lightguide includes a light guiding layer (3610) for propagating light by total internal reflection, and an optical film (3640) that is disposed on the light guiding layer. The optical film includes a plurality of voids, an optical haze that is not less than about 30%, and a porosity that is not less than about 20%. Substantial portions of each two neighboring major surfaces (3614, 3642) in the lightguide are in physical contact with each other. The lightguide can be used as blacklight in a display system.
摘要翻译：公开了一种光导（3690）。光导包括用于通过全内反射传播光的导光层（3610）和设置在导光层上的光学膜（3640）。光学膜包括多个空隙，不小于约30％的光学雾度和不小于约20％的孔隙率。光导中每两个相邻主表面（3614,3642）的实质部分彼此物理接触。光导可以用作显示系统中的黑光。

23. 发明申请

US20120020415A1 METHOD FOR ASSESSING PERCEPTUAL QUALITY 审中-公开
标题翻译：评估质量的方法
公开(公告)号：US20120020415A1
公开(公告)日：2012-01-26
申请号：US12735427
申请日：2009-01-13
申请人： Hua Yang , Tao Liu , Alan Jay Stein
发明人： Hua Yang , Tao Liu , Alan Jay Stein
IPC分类号： H04N7/26
CPC分类号： H04N17/004 , H04N19/14 , H04N19/154 , H04N19/166 , H04N19/172 , H04N19/61 , H04N19/89 , H04N19/895
摘要： The present invention relates to a full-reference (FR) objective method for assessing perceptual quality of decoded video frames in the presence of packet losses and coding artifacts. A method of assessing perceptual quality is provided. First, a value indicating an amount of distortion in a corresponding portion is accessed. Then, that value is classified as packet-loss distortion or coding-artifact distortion. Next, the classified value is modified to account for visibility differences of the human visual system, based on the classification, and then the modified values are combined for the multiple portions, to form a value indicating a total amount of distortion for the multiple portions.
摘要翻译：本发明涉及一种用于在存在分组丢失和编码伪影的情况下评估解码视频帧的感知质量的全参考（FR）目标方法。提供了一种评估感知质量的方法。首先，访问表示对应部分的失真量的值。然后，该值被分类为分组丢失失真或编码伪像失真。接下来，基于分类，对分类值进行修改以考虑人类视觉系统的可见性差异，然后对多个部分组合修改值，以形成表示多个部分的总失真量的值。

24. 发明申请

US20110213145A1 Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners 有权
标题翻译：抑制BCL蛋白与结合伙伴相互作用的化合物和方法
公开(公告)号：US20110213145A1
公开(公告)日：2011-09-01
申请号：US13089530
申请日：2011-04-19
申请人： Alfredo C. Castro , Kristopher M. Depew , Michael J. Grogan , Charles W. Johannes , Edward B. Holson , Brian T. Hopkins , Gregg F. Keaney , Nii O. Koney , Tao Liu , David A. Mann , Marta Nevalainen , Stephane Peluso , Lawrence B. Perez , Daniel A. Snyder , Thomas T. Tibbitts
发明人： Alfredo C. Castro , Kristopher M. Depew , Michael J. Grogan , Charles W. Johannes , Edward B. Holson , Brian T. Hopkins , Gregg F. Keaney , Nii O. Koney , Tao Liu , David A. Mann , Marta Nevalainen , Stephane Peluso , Lawrence B. Perez , Daniel A. Snyder , Thomas T. Tibbitts
IPC分类号： C07D413/12 , C07D413/10 , C07D261/02 , C07D498/04
CPC分类号： C07D261/02 , A61K31/42 , A61K31/422 , A61K31/427 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/5377 , A61K45/06 , C07D413/10 , C07D413/12 , C07D417/12
摘要： The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.
摘要翻译：本发明涉及与bcl蛋白结合并抑制Bcl功能的含异唑烷的化合物。该化合物可用于治疗和调节与过度增生相关的疾病，例如癌症。

25. 发明申请

US20110090423A1 ILLUMINATION DEVICE WITH PROGRESSIVE INJECTION 审中-公开
标题翻译：具有渐进式注射的照明装置
公开(公告)号：US20110090423A1
公开(公告)日：2011-04-21
申请号：US12997269
申请日：2009-05-11
申请人： John A. Wheatley , Rolf W. Biernath , Michael A. Meis , David G. Freier , Tao Liu , Timothy J. Nevitt
发明人： John A. Wheatley , Rolf W. Biernath , Michael A. Meis , David G. Freier , Tao Liu , Timothy J. Nevitt
IPC分类号： G02F1/13357 , F21V7/00 , G02F1/1335
CPC分类号： G02F1/133605 , G02F1/133603 , G02F1/133611
摘要： Illumination devices having a partially transmissive front reflector, a back reflector, and a cavity between them are disclosed. At least one light injector including a baffle and a light source is disposed in the cavity. The light injector is capable of injecting partially collimated light into the cavity. The output area of the illumination device can be increased by disposing light injectors progressively within the cavity, without sacrificing uniformity of the light emitted through the output area.
摘要翻译：公开了具有部分透射的前反射器，后反射器和它们之间的空腔的照明装置。包括挡板和光源的至少一个光注射器设置在空腔中。光注射器能够将部分准直的光注入空腔。可以通过将光注入器逐渐地设置在空腔内来增加照明装置的输出面积，而不会牺牲通过输出区域发射的光的均匀性。

26. 发明申请

US20110028482A1 ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE 有权
标题翻译：作为脂肪酸酰胺水解酶抑制剂的ISOXAZOLINES
公开(公告)号：US20110028482A1
公开(公告)日：2011-02-03
申请号：US12782655
申请日：2010-05-18
申请人： Mark L. Behnke , Alfredo C. Castro , Lawrence K. Chan , Catherine A. Evans , Louis Grenier , Michael J. Grogan , Yves Leblanc , Tao Liu , Stephane Peluso , Daniel A. Snyder , Thomas T. Tibbitts
发明人： Mark L. Behnke , Alfredo C. Castro , Lawrence K. Chan , Catherine A. Evans , Louis Grenier , Michael J. Grogan , Yves Leblanc , Tao Liu , Stephane Peluso , Daniel A. Snyder , Thomas T. Tibbitts
IPC分类号： A61K31/498 , C07D413/04 , A61K31/42 , C07D417/14 , A61K31/4439 , C07D401/14 , A61K31/506 , A61K31/427 , C07D401/04 , A61K31/454 , C07D413/06 , A61K31/496 , C07D417/10 , A61K31/428 , C07D403/10 , C07D401/10 , A61K31/4709 , A61P1/00 , A61P3/00 , A61P9/00 , A61P17/00 , A61P25/00 , A61P27/06 , A61P29/00
CPC分类号： C07D413/04 , C07D261/04 , C07D413/14 , C07D417/04 , C07D417/14
摘要： The present invention provides isoxazoline FAAH inhibitors of the formula (I): or pharmaceutically acceptable forms thereof, wherein each of G, Ra, Rb, Rc, and Rd are as defined herein. The present invention also provides pharmaceutical compositions comprising a compound of formula (I), or a pharmaceutically acceptable form thereof, and a pharmaceutically acceptable excipient.The present invention also provides methods for treating an FAAH-mediated condition comprising administering a therapeutically effective amount of a compound of formula (I), or pharmaceutically acceptable form thereof, to a subject in need thereof.
摘要翻译：本发明提供式（I）的异恶唑啉FAAH抑制剂或其药学上可接受的形式，其中G，Ra，Rb，Rc和Rd各自如本文所定义。本发明还提供包含式（I）化合物或其药学上可接受的形式的药物组合物和药学上可接受的赋形剂。本发明还提供了治疗FAAH介导的病症的方法，包括向有需要的受试者施用治疗有效量的式（I）化合物或其药学上可接受的形式。

27. 发明申请

US20100219803A1 DC TO DC CONVERTER AND METHOD FOR REDUCING OVERSHOOT 有权
标题翻译：直流到直流转换器和减少太阳能的方法
公开(公告)号：US20100219803A1
公开(公告)日：2010-09-02
申请号：US12710860
申请日：2010-02-23
申请人： Wei Han , Ching-Ji Liang , Tao Liu
发明人： Wei Han , Ching-Ji Liang , Tao Liu
IPC分类号： G05F1/10
CPC分类号： H02M3/158
摘要： A DC to DC converter includes a control circuit, a gate driver circuit, and a power stage circuit. The control circuit receives and compares a DC output voltage. When the DC output voltage lower than a first threshold voltage, a PWM signal with a first frequency is outputted, and when the DC output voltage higher than the first threshold voltage, the PWM signal with a second frequency is outputted. The second frequency is higher than the first frequency. The gate driver circuit receives the PWM signal and converts the PWM signal to a first driving signal and a second driving signal. The power stage circuit converts a DC input voltage to the DC output voltage according to the first driving signal and the second driving signal.
摘要翻译： DC-DC转换器包括控制电路，栅极驱动电路和功率级电路。控制电路接收并比较直流输出电压。当DC输出电压低于第一阈值电压时，输出具有第一频率的PWM信号，并且当DC输出电压高于第一阈值电压时，输出具有第二频率的PWM信号。第二频率高于第一频率。栅极驱动电路接收PWM信号，并将PWM信号转换为第一驱动信号和第二驱动信号。功率级电路根据第一驱动信号和第二驱动信号将DC输入电压转换为DC输出电压。

28. 发明申请

US20100153331A1 SYSTEM AND METHOD FOR MANAGING SEMANTIC AND SYNTACTIC METADATA 有权
标题翻译：用于管理语义和数据元数据的系统和方法
公开(公告)号：US20100153331A1
公开(公告)日：2010-06-17
申请号：US12332573
申请日：2008-12-11
申请人： Ock Kee Baek , Arti Abhay Kale , Tao Liu , Pradeep Madaiah
发明人： Ock Kee Baek , Arti Abhay Kale , Tao Liu , Pradeep Madaiah
IPC分类号： G06F17/30
CPC分类号： G06F17/2785 , G06F17/30017
摘要： A method for managing semantic and syntactic metadata. The method begins with receiving heterogeneous data from either a machine or a human. Next, the method captures the semantic metadata corresponding to the received heterogeneous data by means of a semantic template. Next, the method captures the syntactic metadata corresponding to the received heterogeneous data by means of a syntactic template. After capturing the semantic and syntactic metadata, the method logically links the received heterogeneous data with the captured semantic and syntactic metadata. Finally, the method stores the received heterogeneous data in a repository.
摘要翻译：一种用于管理语义和句法元数据的方法。该方法开始于从机器或人机接收异构数据。接下来，该方法通过语义模板捕获与所接收的异构数据相对应的语义元数据。接下来，该方法通过语法模板捕获与所接收的异构数据相对应的句法元数据。在捕获语义和句法元数据之后，该方法将接收到的异构数据与捕获的语义和句法元数据进行逻辑链接。最后，该方法将接收到的异构数据存储在存储库中。

29. 发明申请

US20100015914A1 Methods and equipment for performing channel aware relays in an enhanced relay cluster 有权
标题翻译：在增强型中继集群中执行信道识别中继的方法和设备
公开(公告)号：US20100015914A1
公开(公告)日：2010-01-21
申请号：US12311436
申请日：2007-09-26
申请人： Hui Li , Tao Liu , Xinglin Wang , Yi Sheng Xue , Wolfgang Zirwas
发明人： Hui Li , Tao Liu , Xinglin Wang , Yi Sheng Xue , Wolfgang Zirwas
IPC分类号： H04B3/36
CPC分类号： H04W16/26 , H04B7/15542 , H04B7/2606 , H04W76/20 , H04W84/047
摘要： This invention provides a type of method used for providing channel aware relays in enhanced relay clusters. This method is based on the Centralized Cluster Relay Implementation Proposal, and is implemented by transferring MMR-BS channel information based functions to RS. Specifically, in this invention, RS receives authorization from the MMR-BS to receive the channel information from the MS or next single-hop RS point within its single-hop range, and, after performing applicable channel aware relays, reports the processing result to MMR-BS; MMR-BS configures the signal according to the processing result and joins RS to transmit the control signal to the cluster MS. Using the method provided by this invention can reduce the channel overhead between MMR-BS and RS, and at the same time ensure that the RS composition is simple, and the production costs are low.
摘要翻译：本发明提供了一种用于在增强型继电器集群中提供信道感知中继的方法。该方法基于集中式集群中继实施方案，通过将基于MMR-BS信道信息的功能转移给RS来实现。具体地说，在本发明中，RS接收来自MMR-BS的授权，从MS或其单跳范围内的下一个单跳RS点接收信道信息，在执行适用的信道识别中继之后，将处理结果报告给 MMR-BS; MMR-BS根据处理结果配置信号，并连接RS将控制信号发送到集群MS。使用本发明提供的方法可以降低MMR-BS和RS之间的信道开销，同时确保RS组合简单，生产成本低。

30. 发明申请

US20090309172A1 SENSOR AND A METHOD OF MAKING A SENSOR 有权
标题翻译：传感器和制造传感器的方法
公开(公告)号：US20090309172A1
公开(公告)日：2009-12-17
申请号：US12471903
申请日：2009-05-26
申请人： Tao Liu , Chun Zhang , Ben Wang , Zhiyong Liang
发明人： Tao Liu , Chun Zhang , Ben Wang , Zhiyong Liang
IPC分类号： H01L29/84 , H01L21/00
CPC分类号： G01L1/205 , B82Y10/00 , B82Y15/00
摘要： A sensor is provided, which includes a plurality of conducting elements spaced apart from each other and at least one deformable electrolyte bridge contacting each of the conducting elements at one or more contact points having an aggregate contact area. Upon formation of an ionic circuit between two of the conducting elements, a first resistivity between the two conducting element exists. Upon application of a compressive force on the at least one deformable electrolyte bridge directed toward at least one of the conducting elements, the aggregate contact area increases such that a second resistivity between the two conducting elements exists.
摘要翻译：提供了一种传感器，其包括彼此间隔开的多个导电元件和在具有聚集接触面积的一个或多个接触点处接触每个导电元件的至少一个可变形电解质桥。在两个导电元件之间形成离子电路时，存在两个导电元件之间的第一电阻率。在向至少一个导电元件的至少一个可变形电解质桥施加压缩力时，聚集接触面积增加，使得存在两个导电元件之间的第二电阻率。

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