专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

21. 发明授权

US06653310B2 IL-8 receptor antagonists 失效
标题翻译： IL-8受体拮抗剂
公开(公告)号：US06653310B2
公开(公告)日：2003-11-25
申请号：US10257078
申请日：2002-10-07
申请人： Michael R. Palovich , Katherine L. Widdowson , Hong Nie
发明人： Michael R. Palovich , Katherine L. Widdowson , Hong Nie
IPC分类号： A61K3144
CPC分类号： C07D213/75 , C07D237/22 , C07D237/24
摘要： This invention relates to novel compounds and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
摘要翻译：本发明涉及可用于治疗由趋化因子介导的疾病状态的白细胞介素-8（IL-8）的新化合物及其组合物。

22. 发明授权

US09309467B2 Integrated process for hydrogenation and catalytic cracking of hydrocarbon oil 有权
标题翻译：碳氢化合物氢化和催化裂解的综合工艺
公开(公告)号：US09309467B2
公开(公告)日：2016-04-12
申请号：US12809516
申请日：2008-12-19
申请人： Yongcan Gao , Chaogang Xie , Chuanfeng Niu , Jiushun Zhang , Lishun Dai , Hong Nie , Dadong Li , Jun Long , Jianguo Ma , Yan Cui
发明人： Yongcan Gao , Chaogang Xie , Chuanfeng Niu , Jiushun Zhang , Lishun Dai , Hong Nie , Dadong Li , Jun Long , Jianguo Ma , Yan Cui
IPC分类号： C10G11/18 , C10G51/06 , C10G69/04
CPC分类号： C10G11/18 , C10G11/182 , C10G51/06 , C10G69/04 , C10G2300/1037 , C10G2300/107 , C10G2300/1077 , C10G2300/301 , C10G2300/4006 , C10G2300/4012 , C10G2300/70 , C10G2300/807 , C10G2400/02 , C10G2400/04 , C10G2400/28
摘要： Disclosed is a combination process for improved hydrotreating and catalytic cracking of hydrocarbon oils, including: contacting residual oil, catalytic cracking cycle oil, and optional distillate oil with a hydrotreating catalyst under hydrotreating conditions in the presence of hydrogen followed by separation of the reaction products to obtain gas, hydrogenated naphtha, hydrogenated diesel oil, and hydrogenated tail oil; contacting the hydrogenated tail oil and optional normal catalytic cracking feedstock oil with a cracking catalyst under catalytic cracking conditions followed by separation of the reaction products to obtain dry gas, hydrogenated naphtha, liquefied petroleum gas, catalytic cracked gasoline, catalytic cracked diesel oil, and catalytic cracking cycle oil; wherein the hydrogenated tail oil and/or normal catalytic cracking feedstock oil are separated into at least two fractions, the light and the heavy fractions or normal catalytic cracking heavy feedstock oil and normal catalytic cracking light feedstock oil, prior to contacting the hydrogenated tail oil and/or normal catalytic cracking feedstock oil with the cracking catalyst. The process according to the present invention is especially suitable for conversion of hydrocarbon oils to produce more products of gasoline or diesel oil.
摘要翻译：公开了用于改进烃油的加氢处理和催化裂化的组合方法，包括：在加氢处理条件下在氢气存在下，用加氢处理催化剂将残油，催化裂化循环油和任选的馏出油接触，然后将反应产物分离获得气体，氢化石脑油，氢化柴油和氢化尾油; 在催化裂化条件下使氢化尾油和任选的常规催化裂化原料油与裂化催化剂接触，然后分离反应产物，得到干燥气体，氢化石脑油，液化石油气，催化裂化汽油，催化裂化柴油和催化剂开裂循环油; 其中所述氢化尾油和/或常规催化裂化原料油在将氢化尾油与氢化尾油接触之前分离成至少两个馏分，轻馏分或重馏分或正常催化裂化重原料油和常规催化裂化轻原料油， /或正常催化裂化原料油与裂化催化剂。根据本发明的方法特别适用于烃油的转化以产生更多的汽油或柴油的产物。

23. 发明申请

US20130058381A1 NONLINEAR SIGNAL PROCESSING METHOD AND APPARATUS FOR PULSED-BASED ULTRA-WIDEBAND SYSTEM 审中-公开
标题翻译：基于脉冲超声波系统的非线性信号处理方法及装置
公开(公告)号：US20130058381A1
公开(公告)日：2013-03-07
申请号：US13600681
申请日：2012-08-31
申请人： Zhizhang Chen , Hong Nie , Zhimeng Xu
发明人： Zhizhang Chen , Hong Nie , Zhimeng Xu
IPC分类号： H04B1/707
CPC分类号： H04B1/71637
摘要： A method and apparatus are provided for processing a received pulsed-based ultra-wideband (UWB) signal before the signal is demodulated by an energy detection based receiver. A nonlinear signal processing unit contains one or multiple subunits, and each subunit consists of a nonlinear device and a filter. The nonlinear devices can be any devices that can shift signal, noise, and interference spectra in a nonlinear fashion, and include but are not limited to square law devices and Teager-Kaiser operators. By applying the nonlinear signal processing unit on the received UWB signal, a major part of the energy of noise and narrowband interferences is shifted to specific frequency ranges and then removed by the appropriate filter(s) in the nonlinear signal processing unit. Thus, the signal-to-noise-plus-interference ratio (SNIR) of the received UWB signal can be improved.
摘要翻译：提供一种方法和装置，用于在由基于能量检测的接收机解调信号之前处理接收的基于脉冲的超宽带（UWB）信号。非线性信号处理单元包含一个或多个子单元，每个子单元由非线性设备和滤波器组成。非线性器件可以是可以以非线性方式移动信号，噪声和干扰光谱的任何器件，并且包括但不限于平方律器件和Teager-Kaiser算子。通过对所接收的UWB信号应用非线性信号处理单元，将噪声和窄带干扰能量的主要部分移动到特定频率范围，然后通过非线性信号处理单元中的适当滤波器去除。因此，可以提高接收的UWB信号的信噪比加干扰比（SNIR）。

24. 发明申请

US20080269291A1 Chemical Compounds 审中-公开
标题翻译：化学化合物
公开(公告)号：US20080269291A1
公开(公告)日：2008-10-30
申请号：US12093750
申请日：2006-11-17
申请人： Jeffrey K. Kerns , Jakob Busch-Petersen , Huijie Li , Jeffrey Charles Boehm , Hong Nie , John J. Taggart
发明人： Jeffrey K. Kerns , Jakob Busch-Petersen , Huijie Li , Jeffrey Charles Boehm , Hong Nie , John J. Taggart
IPC分类号： A61K31/454 , C07D401/04
CPC分类号： C07D401/04
摘要： The invention is directed to novel indolecarboxamide derivatives. Specifically, the invention is directed to compounds according to formula (I): where R1, R2, R3 and X are defined below. These compounds are useful in the treatment of disorders associated with inappropriate IKK2 (also known as IKKβ) activity, in particular in the treatment and prevention of disorders mediated by IKK2 mechanisms including inflammatory and tissue repair disorders. Such disorders include rheumatoid arthritis, asthma, and COPD (chronic obstructive pulmonary disease).
摘要翻译：本发明涉及新的吲哚甲酰胺衍生物。具体地，本发明涉及式（I）的化合物：其中R1，R2，R3和X定义如下。这些化合物可用于治疗与不适当的IKK2（也称为IKKβ）活性相关的疾病，特别是治疗和预防包括炎性和组织修复障碍在内的IKK2机制介导的疾病。这些疾病包括类风湿性关节炎，哮喘和COPD（慢性阻塞性肺疾病）。

25. 发明申请

US20070060593A1 4-Carboxamido quinoline derivatives for use as nk-2 and nk-3 审中-公开
标题翻译：用作nk-2和nk-3的4-羧甲酰氨基喹啉衍生物
公开(公告)号：US20070060593A1
公开(公告)日：2007-03-15
申请号：US10561745
申请日：2004-06-23
申请人： Jeffrey Kerns , Hong Nie
发明人： Jeffrey Kerns , Hong Nie
IPC分类号： A61K31/496 , C07D403/02
CPC分类号： C07D215/52 , C07D409/04 , C07D409/14
摘要： Compounds of the formula (I) are disclosed which are NK2 and NK3 receptor antagonists and are useful in the treatment of respiratory diseases: or a pharmaceutically acceptable salt thereof.
摘要翻译：公开了式（I）的化合物，其是NK2和NK3受体拮抗剂，并且可用于治疗呼吸系统疾病：或其药学上可接受的盐。

26. 发明申请

US20060135771A1 Quinoline derivatives as nk-2 and nk-3 receptor antagonists 审中-公开
公开(公告)号：US20060135771A1
公开(公告)日：2006-06-22
申请号：US10542870
申请日：2004-01-29
申请人： Jeffrey Kerns , Qi Jin , Zehong Wan , Hong Nie , Chongjie Zhu
发明人： Jeffrey Kerns , Qi Jin , Zehong Wan , Hong Nie , Chongjie Zhu
IPC分类号： C07D403/14
CPC分类号： C07D409/14
摘要： Compounds of the formula (I) are disclosed which are NK2 and NK3 receptor antagonists and are useful in the treatment of respiratory diseases: or a pharmaceutically acceptable salt thereof.

27. 发明授权

US6166055A Benzoisothiazole compounds useful as IL-8 receptor antagonists 失效
标题翻译：可用作IL-8受体拮抗剂的苯并噻唑化合物
公开(公告)号：US6166055A
公开(公告)日：2000-12-26
申请号：US341382
申请日：1999-07-09
申请人： Katherine L. Widdowson , Hong Nie , Melvin Clarence Rutledge, Jr.
发明人： Katherine L. Widdowson , Hong Nie , Melvin Clarence Rutledge, Jr.
IPC分类号： A61K31/404 , A61K31/416 , A61K31/423 , A61K31/428 , A61P1/00 , A61P1/04 , A61P7/02 , A61P9/00 , A61P11/00 , A61P11/06 , A61P13/12 , A61P17/00 , A61P25/28 , A61P43/00 , C07D209/08 , C07D209/34 , C07D231/56 , C07D261/20 , C07D275/04 , C07D275/06
CPC分类号： C07D275/06 , C07D231/56 , C07D261/20
摘要： This invention relates to compounds of Formula (I), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8). ##STR1##
摘要翻译： PCT No.PCT / US98 / 01292 Sec。 371日期1999年7月9日 102（e）日期1999年7月9日PCT提交1998年1月23日PCT公布。公开号WO98 / 32438 日期：1998年7月30日本发明涉及式（I）化合物及其组合物，其可用于治疗由趋化因子介导的疾病状态，白细胞介素-8（IL-8）。

28. 发明授权

US08696887B2 Catalytic conversion process 有权
标题翻译：催化转化过程
公开(公告)号：US08696887B2
公开(公告)日：2014-04-15
申请号：US12672666
申请日：2008-08-07
申请人： Youhao Xu , Lishun Dai , Longsheng Tian , Shouye Cui , Jianhong Gong , Chaogang Xie , Jiushun Zhang , Jun Long , Zhijian Da , Hong Nie , Jinbiao Guo , Zhigang Zhang
发明人： Youhao Xu , Lishun Dai , Longsheng Tian , Shouye Cui , Jianhong Gong , Chaogang Xie , Jiushun Zhang , Jun Long , Zhijian Da , Hong Nie , Jinbiao Guo , Zhigang Zhang
IPC分类号： C10G11/00
CPC分类号： B01J29/084 , B01J29/46 , B01J29/80 , B01J29/90 , B01J37/0045 , B01J38/30 , B01J2229/42 , C10G11/05 , C10G11/18 , C10G2300/104 , C10G2300/1044 , C10G2300/1055 , C10G2300/107 , C10G2300/1074 , C10G2300/1077 , C10G2300/301 , C10G2300/4006 , C10G2300/4018 , C10G2300/4025 , C10G2300/4093 , C10G2400/02 , C10G2400/06 , C10G2400/20
摘要： A catalytic conversion process which comprises catalytic cracking reaction of a hydrocarbon feedstock contacting with a medium pore size zeolite enriched catalyst in a reactor, characterized in that reaction temperature, weight hourly space velocity and catalyst/feedstock ratio by weight are sufficient to achieve a yield of fluid catalytic cracking gas oil between 12% and 60% by weight of said feedstock, wherein said weight hourly space velocity is between 25 h−1 and 100 h−1, said reaction temperature is between 450° C. and 600° C., and said catalyst/feedstock ratio by weight is between 1 and 30. This invention relates to a catalytic conversion process, especially for heavy feedstock oil to produce higher octane gasoline and an enhanced yield of propylene. More particularly, the invention relates to a process to utilize petroleum oil resources efficiently for decreasing the yield of dry gas and coke significantly.
摘要翻译：催化转化方法，其包括在反应器中与中等孔径的沸石富集催化剂接触的烃原料的催化裂化反应，其特征在于反应温度，重量时空速和催化剂/原料重量比足以实现流化催化裂化瓦斯油在所述原料的12重量％至60重量％之间，其中所述重时空速在25h -1和100h -1之间，所述反应温度在450℃和600℃之间，并且所述催化剂/原料的重量比在1和30之间。本发明涉及催化转化方法，特别是用于重质原料油生产高辛烷值汽油和提高丙烯收率的方法。更具体地说，本发明涉及一种利用石油资源有效降低干燥气体和焦炭产率的方法。

29. 发明授权

US08023571B2 Impulse ultra-wideband radio communication system 有权
标题翻译：脉冲超宽带无线电通信系统
公开(公告)号：US08023571B2
公开(公告)日：2011-09-20
申请号：US12103117
申请日：2008-04-15
申请人： Hong Nie , Zhizhang Chen
发明人： Hong Nie , Zhizhang Chen
IPC分类号： H04L27/00
CPC分类号： H04B1/719 , H04B1/71637
摘要： A method and apparatus are provided for implementing an impulse ultra-wideband communications system which combines the technique of transmitted reference (TR) with a code-sifted reference scheme that separates the reference and the data pulses with a sequence of codes such as a subset of Walsh codes. The combination of the two techniques in ultra-wideband (UWB) radio systems removes the wideband delay elements required by conventional TR UWB systems. The invention provides a system with no analog carriers and lower complexities than other UWB systems, and which has better performances, higher tolerance to nonlinearity, and larger capacities.
摘要翻译：提供了一种用于实现脉冲超宽带通信系统的方法和装置，该脉冲超宽带通信系统将传输参考（TR）的技术与使用诸如子集的子序列分离参考和数据脉冲的代码筛选参考方案进行组合沃尔什码超宽带（UWB）无线电系统中的两种技术的组合消除了传统TR UWB系统所需的宽带延迟元件。本发明提供了一种没有模拟载波和比其他UWB系统更低复杂度的系统，其具有更好的性能，更高的对非线性的容忍性和更大的容量。

30. 发明申请

US20060052365A1 Protease inhibitors 审中-公开
标题翻译：蛋白酶抑制剂
公开(公告)号：US20060052365A1
公开(公告)日：2006-03-09
申请号：US10525114
申请日：2003-08-22
申请人： William Bondinell , Ralph Hall , Qi Jin , Jeffrey Kerns , Hong Nie , Katherine Widdowson
发明人： William Bondinell , Ralph Hall , Qi Jin , Jeffrey Kerns , Hong Nie , Katherine Widdowson
IPC分类号： A61K31/55 , C07D223/12 , C07D403/02
CPC分类号： H04L27/2601 , C07D223/08 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D487/04
摘要： This invention relates 4-amino-azepan-3-ones of formula (I) which are useful as protease inhibitors, particularly of cathepsin S, and as such are useful for preventing a number of diseases amongst which are atherosclerotic lesions and pulmonary diseases such as asthma and allergic reactions.
摘要翻译：本发明涉及式（I）的4-氨基 - 氮杂环庚烷-3-酮，

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式