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21. 发明申请

US20060043284A1 Micro chip, liquid feeding method using the micro chip, and mass analyzing system 审中-公开
标题翻译：微芯片，采用微芯片的液体供给方式，以及质量分析系统
公开(公告)号：US20060043284A1
公开(公告)日：2006-03-02
申请号：US10536407
申请日：2003-11-28
申请人： Masakazu Baba , Toru Sano , Kazuhiro Iida , Hisao Kawaura , Noriyuki Iguchi , Wataru Hattori , Hiroko Someya , Minoru Asogawa
发明人： Masakazu Baba , Toru Sano , Kazuhiro Iida , Hisao Kawaura , Noriyuki Iguchi , Wataru Hattori , Hiroko Someya , Minoru Asogawa
IPC分类号： B01D59/44
CPC分类号： H01J49/04 , B01L3/502707 , B01L3/502746 , B01L2300/069 , B01L2300/0816 , B01L2400/0406 , B01L2400/0683 , B01L2400/0694 , G01N30/6095
摘要： A sample reservoir (205) in which a sample (213) is introduced is sealed by a septum (207). On piercing the septum (207) by an injection needle, the sample reservoir (205) is communicated with the outer atmosphere, and then the sample (213) is delivered from the channel 203 to the water absorbing portion (209).
摘要翻译：其中引入样品（213）的样品储存器（205）由隔膜（207）密封。在通过注射针刺穿隔膜（207）的同时，将样品容器（205）与外部大气连通，然后将样品（213）从通道203输送到吸水部（209）。

22. 发明申请

US20060011480A1 Separation apparatus, method of fabricating the same, and analytical system 审中-公开
标题翻译：分离装置及其制造方法及分析系统
公开(公告)号：US20060011480A1
公开(公告)日：2006-01-19
申请号：US10532978
申请日：2003-10-29
申请人： Toru Sano , Masakazu Baba , Kazuhiro Iida , Hisao Kawaura , Noriyuki Iguchi , Toshitsugu Sakamoto , Wataru Hattori , Hiroko Someya
发明人： Toru Sano , Masakazu Baba , Kazuhiro Iida , Hisao Kawaura , Noriyuki Iguchi , Toshitsugu Sakamoto , Wataru Hattori , Hiroko Someya
IPC分类号： C02F11/00 , G01N27/27
CPC分类号： B01L3/502753 , B01L3/502746 , B01L2300/0681 , B01L2400/086 , G01N27/44704 , G01N27/44773 , G01N30/02 , Y10T29/49002 , B01D15/34
摘要： A separation apparatus (100) has a separation channel (112), a partition wall (301a) and a partition wall (301b), wherein each of the partition wall (301a) and the partition wall (301b) has a capture portion (300) formed thereon. Molecules having a size acceptable by the capture portions (300) provided on the partition wall (301a) and the partition wall (301b) are captured by the capture portion (300) and reduced in the travel speed through the separation channel (112), and this makes it possible to precisely separate the sample depending on the molecular size.
摘要翻译：分离装置（100）具有分离通道（112），分隔壁（301a）和分隔壁（301b），其中分隔壁（301a）和分隔壁（301b）中的每一个具有捕获部分（300）。由分隔壁（301a）和分隔壁（301b）上的被捕获部分（300）可接受的尺寸的分子被捕获部分（300）捕获并且通过分离通道（112）的行进速度减小），这使得可以根据分子尺寸精确地分离样品。

23. 发明授权

US08848703B2 On-chip router and multi-core system using the same 有权
标题翻译：片上路由器和多核系统使用相同
公开(公告)号：US08848703B2
公开(公告)日：2014-09-30
申请号：US13191212
申请日：2011-07-26
申请人： Toru Sano
发明人： Toru Sano
IPC分类号： H04L12/28 , G06F15/173
CPC分类号： G06F15/17381
摘要： A table for changing destination has a destination address in a shared memory and an identifier of a router directly connected to a destination core, in association with each other, and is set by a source core. A search unit performs a first search for searching whether the table has an effective entry having the same address as the destination address in the shared memory, and stored in a header of a write request packet received by the source core. A route calculation unit performs a route calculation with a destination that is a router of an identifier of the entry, if the effective entry is found as a result of the first search. A header generator stores the router identifier obtained by the route calculation in a hop router field of the header of the write request packet, and sets a rerouted flag representing a change in destination.
摘要翻译：用于改变目的地的表具有共享存储器中的目的地地址和与目的地核心直接相连的路由器的标识符，并且由源核心设置。搜索单元执行第一搜索以搜索表具有与共享存储器中的目的地地址相同地址的有效条目，并存储在由源核心接收的写请求分组的报头中。如果作为第一次搜索的结果找到有效条目，则路线计算单元执行作为条目的标识符的路由器的目的地的路线计算。报头生成器将通过路由计算获得的路由器标识符存储在写请求分组的报头的跳转路由器字段中，并且设置表示目的地变化的重新路由标志。

24. 发明申请

US20130250954A1 ON-CHIP ROUTER AND MULTI-CORE SYSTEM USING THE SAME 审中-公开
标题翻译：片上路由器和使用相同的多核系统
公开(公告)号：US20130250954A1
公开(公告)日：2013-09-26
申请号：US13598389
申请日：2012-08-29
申请人： Toru Sano
发明人： Toru Sano
IPC分类号： H04L12/56
CPC分类号： H04L45/06
摘要： An on-chip router of the embodiments has plural input ports that receive packets, plural output ports that transmits the packets, plural buffers, each being provided so as to correspond to each of the input ports and accumulating at least a portion of the packets received through the input ports, a switching unit that switches the output destinations of the packets so that the packets are transmitted from any of the plural output ports, a header analyzer that has plural hop field extractors provided so as to correspond to each of the buffers, and a switching controller that controls the switching unit so that the packets are transmitted from an output port indicated by output port information of the hop field extracted by the hop field extractors.
摘要翻译：实施例的片上路由器具有接收分组的多个输入端口，发送分组的多个输出端口，多个缓冲器，每个缓冲器被提供以对应于每个输入端口并且累积接收到的分组的至少一部分通过输入端口，切换单元，其切换分组的输出目的地，使得分组从多个输出端口中的任一个发送;标题分析器，其具有提供以对应于每个缓冲器的多个跳场提取器，以及切换控制器，其控制所述切换单元，使得从由所述跳跃场提取器提取的所述跳跃信道的输出端口信息指示的输出端口发送所述分组。

25. 发明申请

US20120185633A1 ON-CHIP ROUTER AND MULTI-CORE SYSTEM USING THE SAME 有权
标题翻译：片上路由器和使用相同的多核系统
公开(公告)号：US20120185633A1
公开(公告)日：2012-07-19
申请号：US13191212
申请日：2011-07-26
申请人： Toru Sano
发明人： Toru Sano
IPC分类号： G06F13/00
CPC分类号： G06F15/17381
摘要： A table for changing destination has a destination address in a shared memory and an identifier of a router directly connected to a destination core, in association with each other, and is set by a source core. A search unit performs a first search for searching whether the table has an effective entry having the same address as the destination address in the shared memory, and stored in a header of a write request packet received by the source core. A route calculation unit performs a route calculation with a destination that is a router of an identifier of the entry, if the effective entry is found as a result of the first search. A header generator stores the router identifier obtained by the route calculation in a hop router field of the header of the write request packet, and sets a rerouted flag representing a change in destination.
摘要翻译：用于改变目的地的表具有共享存储器中的目的地地址和与目的地核心直接相连的路由器的标识符，并且由源核心设置。搜索单元执行第一搜索以搜索表具有与共享存储器中的目的地地址相同地址的有效条目，并存储在由源核心接收的写请求分组的报头中。如果作为第一次搜索的结果找到有效条目，则路线计算单元执行作为条目的标识符的路由器的目的地的路线计算。报头生成器将通过路由计算获得的路由器标识符存储在写请求分组的报头的跳转路由器字段中，并且设置表示目的地变化的重新路由标志。

26. 发明授权

US07842514B2 Particle manipulation unit, chip and detection device having the same, mounted thereon, and methods of separating, capturing and detecting proteins 有权
标题翻译：其上安装有颗粒操作单元，芯片和检测装置，以及分离，捕获和检测蛋白质的方法
公开(公告)号：US07842514B2
公开(公告)日：2010-11-30
申请号：US10537292
申请日：2003-11-25
申请人： Wataru Hattori , Masakazu Baba , Toru Sano , Kazuhiro Iida , Hisao Kawaura , Noriyuki Iguchi , Hiroko Someya
发明人： Wataru Hattori , Masakazu Baba , Toru Sano , Kazuhiro Iida , Hisao Kawaura , Noriyuki Iguchi , Hiroko Someya
IPC分类号： G01N33/558
CPC分类号： B01D61/18 , B01D29/00 , B01D67/0062 , B01D69/00 , B01D71/02 , B01D71/027 , B01L3/502746 , B01L3/502753 , B01L3/502761 , B01L2200/0647 , B01L2200/0652 , B01L2300/0816 , B01L2400/086 , G01N33/5302
摘要： A channel (1) formed in a substrate (41) branches into channels (2, 3) at a branch point (43). On this branch point, obstacles (8) having a columnar structure are aligned at certain intervals.
摘要翻译：形成在基板（41）中的通道（1）在分支点（43）处分支成通道（2,3）。在该分支点上，具有柱状结构的障碍物（8）以一定间隔对准。

27. 发明申请

US20090266980A1 MICROCHIP, METHOD FOR USING SUCH MICROCHIP AND MASS SPECTROMETRY SYSTEM 有权
标题翻译： MICROCHIP，使用这种微波和质谱系统的方法
公开(公告)号：US20090266980A1
公开(公告)日：2009-10-29
申请号：US12092357
申请日：2006-11-09
申请人： Toru Sano
发明人： Toru Sano
IPC分类号： H01J49/26
CPC分类号： H01J49/0418 , B01L3/502715 , B01L2200/027 , B01L2200/0642 , B01L2200/10 , B01L2300/0819 , G01N33/6851 , H01J49/0009
摘要： A microchip 100 is employed as target board of mass spectrometry. The microchip 100 includes a substrate 120, a plurality of sample-distributing sections, provided in the substrate 120 and contains samples that serve as a target of a mass spectrometry distributed therein, and a reference material-supplying channel provided in the substrate 120 and capable of being supplied with a reference material in the mass spectrometry. The plurality of sample-distributing sections are provided in the lateral side of the fine channel 102 for distributing the reference material along the fine channel 102 for distributing the reference material.
摘要翻译：使用微芯片100作为质谱的靶板。微芯片100包括基板120，多个样品分配部，设置在基板120中，并且包含用作分布在其中的质谱的靶的样品和设置在基板120中的参考材料供给通道，并且能够在质谱中提供参考物质。多个样本分配部分设置在细通道102的横向侧，用于沿着用于分配参考材料的细通道102分配参考材料。

28. 发明授权

US07586091B2 Mass spectrometric system and mass spectrometry 失效
标题翻译：质谱系统和质谱
公开(公告)号：US07586091B2
公开(公告)日：2009-09-08
申请号：US10549587
申请日：2004-03-15
申请人： Katsutoshi Takahashi , Kazuhiro Iida , Masakazu Baba , Noriyuki Iguchi , Toru Sano , Hisao Kawaura , Toshitsugu Sakamoto , Wataru Hattori , Hiroko Someya
发明人： Katsutoshi Takahashi , Kazuhiro Iida , Masakazu Baba , Noriyuki Iguchi , Toru Sano , Hisao Kawaura , Toshitsugu Sakamoto , Wataru Hattori , Hiroko Someya
IPC分类号： H01J49/00
CPC分类号： H01J49/0418 , B01L3/502746 , B01L3/502753 , B01L2200/0663 , B01L2200/10 , B01L2300/0681 , B01L2300/0816 , B01L2300/16 , B01L2400/086 , G01N1/22 , G01N30/84 , G01N2030/8452
摘要： After a sample is previously separated into plural components in a channel formed in a microchip (353), the channel is irradiated along a separation direction with a laser beam from a laser oscillator (361) to sequentially ionize each fraction separated in the channel. The ionized fraction is detected by a mass spectrometry unit (363) and analyzed by an analytical result analyzing unit (371). The analytical result is stored in a memory (369) while associated with position information in a driver control unit (367) and information on laser beam irradiation condition in a laser control unit (373), and the analytical result is imaged by an imaging unit (375). The imaged analytical result is displayed on a display (377).
摘要翻译：在将样品预先分离成在微芯片（353）中形成的通道中的多个部件之后，通过激光振荡器（361）的激光束沿着分离方向照射通道，以顺序地电离通道中分离的每个部分。通过质谱分析单元（363）检测离子化分数，用分析结果分析单元（371）进行分析。分析结果与激光控制单元（373）中的驱动器控制单元（367）中的位置信息和激光束照射条件的信息相关联地存储在存储器（369）中，并且分析结果由成像单元（375）。成像分析结果显示在显示器上（377）。

29. 发明申请

US20090070045A1 DIAGNOSIS SUPPORTING SYSTEM 审中-公开
标题翻译：诊断支持系统
公开(公告)号：US20090070045A1
公开(公告)日：2009-03-12
申请号：US12263147
申请日：2008-10-31
申请人： Wataru HATTORI , Toru Sano , Masakazu Baba , Kazuhiro Iida , Hisao Kawaura , Noriyuki Iguchi , Hiroko Someya
发明人： Wataru HATTORI , Toru Sano , Masakazu Baba , Kazuhiro Iida , Hisao Kawaura , Noriyuki Iguchi , Hiroko Someya
IPC分类号： G06F19/00 , G06F17/18
CPC分类号： G01N27/44717 , G16H10/60 , G16H15/00
摘要： A diagnosis supporting system (10) includes a diagnosis data obtaining unit (20) that obtains diagnosis data in which a movement parameter reflecting a movement speed of each component in separating a sample collected from a test subject into plural components with a chip (12) and a character of each component is in correspondence, a parameter storing unit (34) that stores the movement parameter of a characteristic component showing a state of suffering from a specific disease in correspondence with the disease, a relationship data storing unit (35) that stores relationship data showing a relationship between the character of the characteristic component and a possibility of suffering from a specific disease, a detecting unit (21) that detects the characteristic component from the diagnosis data based on the movement parameter of the characteristic component and the movement parameter of the diagnosis data by making reference to the parameter storing unit (34), and an inference processing unit (22) that infers the possibility that the test subject is suffering by making reference to the relationship data storing unit (35) based on the character of the detected characteristic component.
摘要翻译：诊断支持系统（10）包括诊断数据获取单元（20），该诊断数据获取单元（20）获取诊断数据，其中，用芯片（12）将反映从测试对象收集的样本的每个组件的移动速度反映成多个组件的移动参数，并且每个部件的字符相对应，存储与疾病相对应地显示出患有特定疾病的状态的特征部件的移动参数的参数存储部（34），关系数据存储部（35），其中，存储表示特征成分的特征与患有特定疾病的可能性之间的关系的关系数据，根据特征成分的移动参数和运动来检测来自诊断数据的特征成分的检测部（21）参考存储单元（34）的诊断数据的参数以及推断处理（22），其基于检测到的特征分量的特性，参考关系数据存储单元（35）推测测试对象遭受的可能性。

30. 发明授权

US07274016B2 Liquid switch, and microchip and mass-analyzing system using the same 失效
标题翻译：液体开关，微芯片和质量分析系统使用相同
公开(公告)号：US07274016B2
公开(公告)日：2007-09-25
申请号：US10537295
申请日：2003-12-02
申请人： Kazuhiro Iida , Masakazu Baba , Hisao Kawaura , Toru Sano , Noriyuki Iguchi , Hiroko Someya , Wataru Hattori , Minoru Asogawa
发明人： Kazuhiro Iida , Masakazu Baba , Hisao Kawaura , Toru Sano , Noriyuki Iguchi , Hiroko Someya , Wataru Hattori , Minoru Asogawa
IPC分类号： G01N21/69 , H01J49/00 , B01D59/44
CPC分类号： B01L3/502738 , B01L3/502746 , B01L2200/0621 , B01L2400/0688 , G01N30/20 , H01J49/04 , Y10T137/4891
摘要： A liquid sample (104) introduced in a main flow passage (101) is held in a dam portion (105), and a trigger liquid (106) is filled in a trigger flow passage (102). In this state, the trigger liquid (106) is further introduced at desired timing into the trigger flow passage (102) so that the front end portion of the level of the trigger liquid (106) is advanced and the front end portion is brought to be into contact with the dam portion (105). This causes the liquid sample (104) to move to the right (downstream side) in the figure, resulting in the liquid sample (104) flowing out to the downstream side of the main flow passage (101). This means that the trigger liquid (106) provides priming to realize a liquid switch.
摘要翻译：引入到主流路（101）中的液体样品（104）保持在坝部（105）中，并且将触发液体（106）填充在触发流路（102）中。在这种状态下，触发液体（106）在所需的时刻被进一步引入到触发流路（102）中，使得触发液体（106）的高度的前端部分前进，前端部分与坝部（105）接触。这使得液体样品（104）移动到图中的右侧（下游侧），导致液体样品（104）流出到主流动通道（101）的下游侧。这意味着触发液体（106）提供启动以实现液体开关。

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