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    • 21. 发明授权
    • Heterocyclic substituted isoxazolidines and their use as fungicides
    • 杂环取代的异恶唑烷并用作杀真菌剂
    • US06313147B1
    • 2001-11-06
    • US09520736
    • 2000-03-08
    • Steven Howard ShaberLixin ZhangEdward Michael SzapacsJames Allen Quinn
    • Steven Howard ShaberLixin ZhangEdward Michael SzapacsJames Allen Quinn
    • C07D41304
    • C07D413/04A01N43/80C07D413/14
    • Compounds with fungicidal properties having formula X is CH or nitrogen; R is (C1-C12)alkyl, halo(C1-C12)alkyl, (C2-C8)alkenyl, halo(C2-C8)alkenyl, (C2-C8)alkynyl, halo(C2-C8)alkynyl, (C1-C12)alkoxy(C1-C12)alkyl, (C3-C7)cycloalkyl, halo(C3-C7)cycloalkyl, (C3-C7)cycloalkyl(C1-C4)alkyl, aralkyl, aryloxy(C1-C4)alkyl or heterocyclic; R1 is aryl, heterocyclic or C(R6R7R8). R2 and R3 are each selected from hydrogen, (C1-C12)alkyl, halo(C1-C12)alkyl, (C1-C12)alkoxy, halo(C1-C12)alkoxy, (C3-C7)cycloalkyl, (C3-C7)cycloalkyl(C1-C4)alkyl, aryl, aralkyl, heterocyclic; cyano, and (C1-C4)alkoxycarbonyl; R4 and R5 are each selected from hydrogen, (C1-C12)alkyl, halo(C1-C12)alkyl, (C2-C8)alkenyl, halo(C2-C8)alkenyl, (C2-C8)alkynyl, halo(C2-C8)alkynyl, (C3-C7)cycloalkyl, halo(C3-C7)cycloalkyl, (C3-C7)cycloalkyl(C1-C4)alkyl, aryl, aryloxy(C1-C4)alkyl, aralkyl, heterocyclic, cyano, and (C1-C4)alkoxycarbonyl such that R4 and R5 are not both hydrogen; R6, R7, and R8 are each selected from hydrogen, (C1-C12)alkyl, (C2-C8)alkenyl, (C2-C8)alkynyl, (C1-C12)alkoxy(C1-C12)alkyl, (C3-C7)cycloalkyl, (C3-C7)cycloalkyl(C1-C4)alkyl, aryl, aralkyl, and heterocyclic(C1-C4)alkyl.
    • 具有式X的具有杀真菌性的化合物是CH或氮; (C 2 -C 8)烯基,(C 2 -C 8)烯基,(C 2 -C 8)炔基,卤代(C 2 -C 8)炔基,(C 1 -C 8) C 1 -C 4烷基,C 1 -C 4烷基,C 1 -C 4烷基,(C 1 -C 4)烷基,C 3 -C 7环烷基, R1是芳基,杂环或C(R6R7R8)。 R2和R3分别选自氢,(C1-C12)烷基,卤代(C1-C12)烷基,(C1-C12)烷氧基,卤代(C1-C12)烷氧基,(C3-C7)环烷基,(C3-C7) )环烷基(C 1 -C 4)烷基,芳基,芳烷基,杂环; 氰基和(C 1 -C 4)烷氧基羰基; R4和R5各自选自氢,(C1-C12)烷基,卤代(C1-C12)烷基,(C2-C8)烯基,卤代(C2-C8)烯基,(C2-C8)炔基, (C 3 -C 7)环烷基,(C 3 -C 7)环烷基,(C 3 -C 7)环烷基(C 1 -C 4)烷基,芳基,芳氧基(C 1 -C 4)
    • 24. 发明授权
    • Benzyloxy substituted aromatics and their use as fungicides and
insecticides
    • US5945557A
    • 1999-08-31
    • US102713
    • 1998-06-23
    • Ronald RossTed Tsutomu FujimotoSteven Howard Shaber
    • Ronald RossTed Tsutomu FujimotoSteven Howard Shaber
    • A01N37/38A01N37/42A01N37/50A01N43/08A01N43/10A01N43/40A01N43/54C07C69/734C07C69/736C07C69/738C07C69/743C07C69/757C07C251/44C07C251/48C07C255/46C07D213/30C07D213/50C07D213/55C07D213/57C07D239/26C07D307/42C07D307/46C07D333/16C07D333/22C07C69/76C07C233/00
    • C07D213/30A01N37/38A01N37/50C07C251/44C07C251/48C07C255/46C07C69/736C07C69/757C07D213/50C07D239/26C07D307/42C07D307/46C07D333/16C07D333/22C07C2101/02
    • Compounds with fungicidal and insecticidal properties having formula ##STR1## wherein A is N or CH; V is O or NH; m and n are the integers 0 and 1, provided that m+n is 0 or 1;X is independently selected from hydrogen, halo, (C.sub.1 -C.sub.4)alkyl, and (C.sub.1 -C.sub.4)alkoxy;R is independently selected from hydrogen, (C.sub.1 -C.sub.12)alkyl, (C.sub.1 -C.sub.12)alkoxy, halo(C.sub.1 -C.sub.12)alkyl, (C.sub.2 -C.sub.12)alkenyl, (C.sub.2 -C.sub.12)alkynyl, (C.sub.1 -C.sub.12)alkoxy(C.sub.1 -C.sub.12)alkyl, (C.sub.3 -C.sub.7)cycloalkyl, halo(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.3 -C.sub.7)cycloalkyl(C.sub.1 -C.sub.12)alkyl, (C.sub.3 -C.sub.7)cycloalkyl(C.sub.2 -C.sub.12)alkenyl, (C.sub.3 -C.sub.7)cycloalkyl(C.sub.2 -C.sub.12)alkynyl, (C.sub.1 -C.sub.12)alkyl(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.1 -C.sub.12)alkoxy(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.1 -C.sub.12)alkoxy(C.sub.1 -C.sub.12)alkyl(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.2 -C.sub.12)alkenyl(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.2 -C.sub.12)alkynyl(C.sub.3 -C.sub.7)cycloalkyl, halo(C.sub.1 -C.sub.12)alkyl(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.1 -C.sub.12)alkoxy(C.sub.2 -C.sub.12)alkenyl(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.1 -C.sub.12)alkoxy(C.sub.2 -C.sub.12)alkynyl(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.3 -C.sub.7)cycloalkyl(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.1 -C.sub.12)alkyl(C.sub.3 -C.sub.7)cycloalkyl(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.2 -C.sub.12)alkenyl(C.sub.3 -C.sub.7)cycloalkyl(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.2 -C.sub.12)alkynyl(C.sub.3 -C.sub.7)cycloalkyl(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.3 -C.sub.7)cycloalkyl(C.sub.1 -C.sub.12)alkyl(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.3 -C.sub.7)cycloalkyl(C.sub.2 -C.sub.12)alkenyl(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.3 -C.sub.7)cycloalkyl(C.sub.2 -C.sub.12)alkynyl(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.3 -C.sub.7)cycloalkyl(C.sub.1 -C.sub.12)alkoxy(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.3 -C.sub.7)cycloalkyl(C.sub.1 -C.sub.12)alkoxy(C.sub.1 -C.sub.12)alkyl(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.3 -C.sub.7)cycloalkyl(C.sub.1 -C.sub.12)alkoxy(C.sub.1 -C.sub.12)alkenyl(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.3 -C.sub.7)cycloalkyl(C.sub.1 -C.sub.12)alkoxy(C.sub.1 -C.sub.12)alkynyl(C.sub.3 -C.sub.7)cycloalkyl, aryl, aralkyl, aryl(C.sub.3 -C.sub.7)cycloalkyl, aryl(C.sub.3 -C.sub.7)cycloalkyl(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.3 -C.sub.7)cycloalkylaryl, aryl(C.sub.1 -C.sub.4)alkyl(C.sub.3 -C.sub.7)cycloalkyl, heterocyclic, aryl(C.sub.1 -C.sub.4)alkylheterocyclic heterocyclic(C.sub.1 -C.sub.4)alkyl, heterocyclic(C.sub.3 -C.sub.7)cycloalkyl andR.sub.1, R.sub.2, R.sub.3 and R.sub.4 are independently selected from hydrogen, halogen, (C.sub.1 -C.sub.12)alkyl, (C.sub.1 -C.sub.12)alkoxy, halo(C.sub.1 -C.sub.12)alkyl, (C.sub.2 -C.sub.12)alkenyl, (C.sub.2 -C.sub.12)alkynyl, (C.sub.3 -C.sub.7)cycloalkyl, cyano, carboxy, (C.sub.1 -C.sub.4)alkoxycarbonyl, aryl, and when taken together R.sub.2 and R.sub.3 form a (C.sub.3 -C.sub.7)cycloalkyl ring, provided that when n=0 or 1 and m=0 R and R.sub.1 are not both hydrogen and when A is N and V is NH and n and m are both zero than R, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are other than 1 to 3 substituents independently selected from halogen and (C.sub.1 -C.sub.4)alkyl.