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21. 发明授权

US06846319B2 Devices for sealing openings through tissue and apparatus and methods for delivering them 有权
标题翻译：用于通过组织和装置密封开口的装置和用于传送它们的方法
公开(公告)号：US06846319B2
公开(公告)日：2005-01-25
申请号：US09738431
申请日：2000-12-14
申请人： Richard S. Ginn , Stephen M. Salmon , Ronald J. Jabba
发明人： Richard S. Ginn , Stephen M. Salmon , Ronald J. Jabba
IPC分类号： A61B10/00 , A61B17/00 , A61B17/08
CPC分类号： A61B17/0057 , A61B2010/0003 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672 , A61B2017/00898
摘要： An apparatus for sealing a passage through tissue includes an elongate shaft and a cylindrical plug disposed on a distal end of the shaft, the plug including a helical thread on its outer surface. Intestinal submucosa may be secured to the plug, e.g., in a cavity in its distal end, that may be delivered into the passage. Alternatively, the plug may be formed from a bioabsorbable material and may be released from the shaft within the passage. The plug is threaded into the passage, thereby engaging the tissue to seal the passage. The shaft is rotated until it engages a blood vessel within the tissue while monitoring blood flow through the vessel. The shaft is rotated to thread the plug into the passage until blood flow ceases through the vessel, whereupon rotation of the shaft is reversed to back the plug until blood flow through the vessel resumes.
摘要翻译：用于密封通过组织的通道的装置包括细长轴和设置在轴的远端上的圆柱塞，该塞在其外表面上包括螺旋形螺纹。肠粘膜下层可以固定到栓塞，例如在其远端的空腔中，其可以被输送到通道中。或者，插塞可以由生物可吸收材料形成，并且可以在通道内从轴释放。塞子被拧入通道中，从而接合组织以密封通道。旋转轴直到其与组织内的血管接合，同时监测通过血管的血流。轴被旋转以将塞子螺纹连接到通道中，直到血流停止通过血管，由此轴的旋转被反向以回到塞子，直到通过血管的血液流动恢复。

22. 发明授权

US5620417A Rapid exchange delivery catheter 失效
标题翻译：快速交换导管
公开(公告)号：US5620417A
公开(公告)日：1997-04-15
申请号：US271878
申请日：1994-07-07
申请人： Yue-Teh Jang , Richard S. Ginn , Stephen M. Salmon
发明人： Yue-Teh Jang , Richard S. Ginn , Stephen M. Salmon
IPC分类号： A61M25/00 , A61B17/22 , A61B19/00 , A61F2/06 , A61F2/84 , A61M25/01 , A61M29/02 , A61M29/00
CPC分类号： A61M25/0169 , A61F2/958 , A61B2017/22051 , A61B2090/3782 , A61M2025/0183 , A61M2025/0681 , A61M25/104
摘要： A catheter exchange member is provided for reducing exchange time when replacing one catheter (or similar device) with another in the vascular anatomy of a patient. The catheter exchange member includes a tubular body having a proximal and a distal end and a central lumen. A tapered fixture having a distal port and a proximal opening which is larger than the distal port is attached to the tubular body at the distal port. An elongate shaft is attached to and extends proximally from either the tapered fixture or the tubular body. The exchange member is preferably used within a conventional guiding catheter where the tubular body is advanced through a distal end of the guiding catheter and into the coronary artery while the tapered fixture remains in the guiding catheter. This configuration allows various therapeutic and diagnostic devices to be stored within the guiding catheter just proximal to the tapered fixture. One of the devices can be placed within the coronary artery by simply advancing it through the tapered fixture which channels the device into the tubular body and into the coronary artery. The device may be replaced with another by simply removing it and advancing the second device into the tapered fixture and into the coronary artery.
摘要翻译：提供了一种导管更换构件，用于在将患者的血管解剖结构中的另一导管（或类似装置）替换为另一导管时减少交换时间。导管更换构件包括具有近端和远端以及中心腔的管状体。具有远端口和大于远端口的近端开口的锥形固定件在远端口处附接到管状体。细长轴连接到锥形夹具或管状体的近侧并从其延伸。交换构件优选地用在传统的导向导管内，其中管状体前进通过导向导管的远端并进入冠状动脉，同时锥形夹具保持在引导导管中。这种配置允许各种治疗和诊断装置被存储在紧邻锥形固定装置的引导导管内。其中一个装置可以通过简单地将其推进通过锥形固定器而放置在冠状动脉内，该锥形夹具将装置引导到管状体中并进入冠状动脉。该装置可以通过简单地将其移除并将第二装置推入锥形固定装置并进入冠状动脉来替换。

23. 发明授权

US5368049A Superelastic formable guidewire with malleable cladding 失效
标题翻译：具有可延展包层的超弹性可成形导丝
公开(公告)号：US5368049A
公开(公告)日：1994-11-29
申请号：US138554
申请日：1993-10-15
申请人： L. Venkata Raman , Stephen M. Salmon
发明人： L. Venkata Raman , Stephen M. Salmon
IPC分类号： A61M25/01 , A61B5/00 , A61M20060101 , A61M25/09
CPC分类号： A61M25/09 , A61M2025/09083 , A61M2025/09175 , A61M2205/0266
摘要： A guidewire is provided having a malleable segment extending beyond a superelastic tip portion of the guidewire. Such a configuration provides a guidewire which is resistant to kinking and plastic deformation in the superelastic portion, but which has a distal segment which can be shaped by a physician immediately prior to use in a surgical procedure. The malleable segment can be attached to the distal end of the superelastic tip portion, or alternatively, can result from a malleable coating on a portion of the superelastic tip, wherein the coating is thick enough to allow the coated portion of the tip to be formed into a desired shape. The malleable segment can be radiopaque to ease fluoroscopic visualization of the guidewire. In addition, the entire guidewire located proximally to the malleable segment can be fabricated from a superelastic alloy to provide resistance to kinking and plastic deformation along virtually the entire length of the guidewire.
摘要翻译：提供导丝，其具有延伸超过导丝的超弹性末端部分的延展部分。这种构造提供了一种能够在超弹性部分中抵抗扭结和塑性变形的导丝，但是其具有可以在外科手术中使用之前立即由医师形成的远端部分。可延展部分可以附接到超弹性末端部分的远端，或者可以由超弹性末端的一部分上的可延展涂层产生，其中涂层足够厚以允许尖端的涂覆部分形成成为所需的形状。可延展部分可以是不透射线的，以便于导丝的透视可视化。此外，位于可延展部分的近侧的整个导丝线可以由超弹性合金制成，以提供几乎在导丝的整个长度上的扭结和塑性变形的阻力。

24. 发明授权

US5201316A Guide wire receptacle for catheters having rigid housings 失效
标题翻译：具有刚性外壳的导管的导线插座
公开(公告)号：US5201316A
公开(公告)日：1993-04-13
申请号：US672069
申请日：1991-03-18
申请人： Mark L. Pomeranz , Stephen M. Salmon , Pat A. Gingell
发明人： Mark L. Pomeranz , Stephen M. Salmon , Pat A. Gingell
IPC分类号： A61B8/12
CPC分类号： A61B8/12 , A61B8/445 , A61B8/4488 , A61M2025/0183
摘要： An ultrasonic imaging catheter comprises a flexible catheter body having a rigid housing at its distal end. A tapered flexible end piece is secured to the distal end of the rigid housing, and a flexible guide wire tube extends in parallel to both the housing and the flexible end piece from the catheter body. The guide wire tube defines a guide wire lumen capable of receiving a movable guide wire, and the combined structure of the housing, flexible end piece, and flexible guide wire tube minimize constriction of the guide wire as it passes through the guide wire lumen.
摘要翻译：超声成像导管包括在其远端具有刚性壳体的柔性导管主体。锥形柔性端件固定到刚性壳体的远端，并且柔性导丝管从导管主体平行于壳体和柔性端件平行延伸。导丝管限定能够接收可移动导丝的导丝管腔，并且当引导丝穿过导丝管腔时，引导线的收缩最小化，壳体，柔性端部件和柔性引导线管的组合结构最小化。

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