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21. 发明授权

US08455532B2 Pyrazolyl acrylonitrile compounds and uses thereof 有权
标题翻译：吡唑基丙烯腈化合物及其用途
公开(公告)号：US08455532B2
公开(公告)日：2013-06-04
申请号：US13265010
申请日：2010-04-27
申请人： Bin Li , Haibo Yu , Hong Zhang , Yan Cheng , Yanmei Luo , Lizeng Wang , Hongfei Wu , Man Xu
发明人： Bin Li , Haibo Yu , Hong Zhang , Yan Cheng , Yanmei Luo , Lizeng Wang , Hongfei Wu , Man Xu
IPC分类号： A01N43/56 , C07D231/12
CPC分类号： C07D231/12 , A01N43/56 , A01N53/00 , C07D231/14 , C07D231/16
摘要： A kind of pyrazolyl acrylniitrile compounds represented by the structures of formula I or stereoisomers thereof are disclosed in the present invention. Where in: R1 is selected from the group of substituents consisting of H, C1-C4 alkoxy C1-C2 alkyl, C3-C5 alkenyloxy C1-C2 alkyl, C3-C5 alknyloxy C1-C2 alkyl, C1-C4 alkylthio C1-C2 alkyl, C1-C5 alkyl carbonyl, C3-C8 cycloalkyl carbonyl, C1-C5 alkoxy carbonyl or C1-C5 alkylthio carbonyl; R2 is Cl or methyl; R3 is H, methyl, CN, NO2 or halogen. Or its stereoisomers.The Formula I compounds have high insecticidal activities or acaricidal activities, so they can be used as insecticide or acaricide.
摘要翻译：在本发明中公开了一种由式I结构或其立体异构体表示的吡唑基丙烯腈化合物。其中：R1选自H，C1-C4烷氧基C1-C2烷基，C3-C5烯氧基C1-C2烷基，C3-C5烷氧基C1-C2烷基，C1-C4烷硫基C1-C2烷基，C 1 -C 5烷基羰基，C 3 -C 8环烷基羰基，C 1 -C 5烷氧基羰基或C 1 -C 5烷硫基羰基; R2是Cl或甲基; R3是H，甲基，CN，NO2或卤素。或其立体异构体。式I化合物具有高杀虫活性或杀螨活性，因此可用作杀虫剂或杀螨剂。

22. 发明授权

US08455398B2 Amide compounds, preparation methods and uses thereof 有权
标题翻译：酰胺化合物，其制备方法和用途
公开(公告)号：US08455398B2
公开(公告)日：2013-06-04
申请号：US12990194
申请日：2009-06-03
申请人： Changling Liu , Baoshan Chai , Hong Zhang , Jichun Yang , Zhinian Li , Yongwu Peng , Junfeng Wang , Jiao Wu , Shicun Ma , Miao Li
发明人： Changling Liu , Baoshan Chai , Hong Zhang , Jichun Yang , Zhinian Li , Yongwu Peng , Junfeng Wang , Jiao Wu , Shicun Ma , Miao Li
IPC分类号： A01N43/40 , A01N43/50 , C07D213/72 , C07D401/14 , C07D401/02
CPC分类号： A01N43/60 , A01N43/56 , A01N53/00 , C07D211/04 , C07D213/74 , C07D231/10 , C07D237/06 , C07D239/24 , C07D401/14 , C07D403/12 , C07D403/14
摘要： Amide compounds, preparation methods and uses thereof. The structure of the compounds is represented as the general formula (I), in which the definitions of substituents are illuminated as description. The present amide compounds have broad spectrum activity of killing pests and are effective on lepidopteran pests including ostrinia nubilalis, sugarcane borer, adoxophyes orana fischer von reslerstamm, apple fruit borer, grapholitha inopinata, lymantri dispar l., cnaphalocrocis medinalis, ostrinia furnacalis, helicoverpa assulta, grapholitha inopinata, plutella xylostella, spodoptera exigua, prodenia litura etc., especially for plutella xylostella, spodoptera exigua. The present amide compounds can obtain good effect at very low dosage. At the same time, some compounds have good fungicidal activity which can be used to prevent rice blast, phytophthora infestans, cucumber downy mildew or grey mold of vegetables.
摘要翻译：酰胺化合物，其制备方法和用途。化合物的结构表示为通式（I），其中取代基的定义被描述为照亮。本发明的酰胺化合物具有杀虫害虫的广谱活性，对鳞翅目害虫有效，包括鸵鸟，甘蔗螟，苹果果螟，，，ata ata ata，，，，disp disp disp a a a a a a a a a a a a a a a a a ，鹅掌楸，小菜蛾，草地贪夜蛾，小蠊等，特别是小菜蛾，草地贪夜蛾。本发明的酰胺化合物可以在非常低的剂量下获得良好的效果。同时，一些化合物具有良好的杀真菌活性，可用于预防稻瘟病，致病疫霉，黄瓜霜霉病或蔬菜灰霉病。

23. 发明授权

US08334372B2 Modulation of factor 11 expression 有权
标题翻译：调节因子11表达
公开(公告)号：US08334372B2
公开(公告)日：2012-12-18
申请号：US12580241
申请日：2009-10-15
申请人： Susan M. Freier , Brett P. Monia , Hong Zhang , Chenguang Zhao , Jeffrey R. Crosby , Andrew M. Siwkowski
发明人： Susan M. Freier , Brett P. Monia , Hong Zhang , Chenguang Zhao , Jeffrey R. Crosby , Andrew M. Siwkowski
IPC分类号： C07H21/02 , C07H21/04
CPC分类号： A61K31/7125 , A61K31/366 , A61K31/4365 , A61K31/4545 , A61K31/713 , A61K31/727 , A61K31/737 , C07H21/00 , C12N15/1137 , C12N2310/11 , C12N2310/315 , C12N2310/321 , C12N2310/3341 , C12N2310/341 , C12N2310/346 , C12Y304/21027
摘要： Disclosed herein are antisense compounds and methods for decreasing Factor 11 and treating or preventing thromboembolic complications in an individual in need thereof. Examples of disease conditions that can be ameliorated with the administration of antisense compounds targeted to Factor 11 include thrombosis, embolism, and thromboembolism, such as, deep vein thrombosis, pulmonary embolism, myocardial infarction, and stroke. Antisense compounds targeting Factor 11 can also be used as a prophylactic treatment to prevent individuals at risk for thrombosis and embolism.
摘要翻译：本文公开了用于减少因子11并在需要其的个体中治疗或预防血栓栓塞并发症的反义化合物和方法。通过施用靶向因子11的反义化合物可以改善的疾病状况的实例包括血栓形成，栓塞和血栓栓塞，例如深静脉血栓形成，肺栓塞，心肌梗塞和中风。靶向因子11的反义化合物也可用作预防性治疗，以预防患有血栓形成和栓塞风险的个体。

24. 发明申请

US20120307625A1 Method and Apparatus For Selecting Between Available Neighbors in a RAPID Alternate Path Calculation 有权
标题翻译：用于在RAPID替代路径计算中的可用邻居之间选择的方法和装置
公开(公告)号：US20120307625A1
公开(公告)日：2012-12-06
申请号：US13588126
申请日：2012-08-17
申请人： Ravi Ravindran , Peter Ashwood Smith , Hong Zhang
发明人： Ravi Ravindran , Peter Ashwood Smith , Hong Zhang
IPC分类号： H04L12/437 , H04L12/24 , H04L12/42
CPC分类号： H04L45/12 , H04L41/06 , H04L45/00 , H04L45/02 , H04L45/123 , H04L45/18 , H04L45/22 , H04L45/28
摘要： A weighting process may be used to select between alternate neighbors in a RAPID calculation to enable policy and/or traffic engineering considerations to affect the selection of an alternate path through the network. The information used to weight the neighbors may static administratively assigned weighting information or dynamic weighting information such as local statistical traffic condition information. The process may take into account the amount of traffic being handled by the current primary next hop for the destination, the available capacity of the available alternate neighbors, the ability of the alternate neighbors to handle the additional traffic, and other considerations. Weighting may occur after a set of available loop free alternate neighbors has been determined. Alternatively, weighting may occur before the RAPID calculation has been performed to cause the neighbors to be ordered prior to RAPID processing. This may enable RAPID calculation to stop without considering all available neighbors.
摘要翻译：可以使用加权过程来在RAPID计算中的备选邻居之间进行选择，以使策略和/或流量工程注意事项能够影响通过网络的备用路径的选择。用于加权邻居的信息可以静态地管理地分配加权信息或动态加权信息，例如本地统计交通状况信息。该过程可以考虑由目的地的当前主要下一跳处理的业务量，可用备用邻居的可用容量，备用邻居处理附加业务的能力以及其他考虑。在确定了一组可用的无环路交替邻居之后，可能会发生加权。或者，可以在执行RAPID计算之前进行加权，以使得在RAPID处理之前对邻居进行排序。这可能使RAPID计算停止，而不考虑所有可用的邻居。

25. 发明授权

US08318266B2 Enhanced copper growth with ultrathin barrier layer for high performance interconnects 有权
公开(公告)号：US08318266B2
公开(公告)日：2012-11-27
申请号：US11470922
申请日：2006-09-07
申请人： Ling Chen , Hua Chung , Barry L. Chin , Hong Zhang
发明人： Ling Chen , Hua Chung , Barry L. Chin , Hong Zhang
IPC分类号： C23C16/00 , C23C14/02 , H05H1/00
CPC分类号： H01L21/28562 , C23C16/34 , C23C16/4411 , C23C16/4412 , C23C16/45504 , C23C16/45508 , C23C16/45512 , C23C16/45525 , C23C16/45544 , C23C16/45563 , C23C16/45582 , H01L21/76843 , H01L21/76846 , H01L21/76871
摘要： A method for depositing a refractory metal nitride barrier layer having a thickness of about 20 angstroms or less is provided. In one aspect, the refractory metal nitride layer is formed by introducing a pulse of a metal-containing compound followed by a pulse of a nitrogen-containing compound. The refractory metal nitride barrier layer provides adequate barrier properties and allows the grain growth of the first metal layer to continue across the barrier layer into the second metal layer thereby enhancing the electrical performance of the interconnect.

26. 发明申请

US20120290728A1 Data card and method for quickly establishing dial-up connection thereof 有权
标题翻译：用于快速建立拨号连接的数据卡和方法
公开(公告)号：US20120290728A1
公开(公告)日：2012-11-15
申请号：US13522519
申请日：2010-09-17
申请人： Hong Zhang
发明人： Hong Zhang
IPC分类号： G06F15/16
CPC分类号： H04W76/02 , H04L29/12216 , H04L29/12311 , H04L61/2015 , H04W28/18 , H04W76/10
摘要： The disclosure provides a method for quickly establishing a dial-up connection by using a data card, which comprises: when a mobile terminal initiates the dial-up connection from a computer, performing both a process of initiating a wireless connection establishment through a Unified Messaging (Um) port and a process of initiating a Dynamic Host Configuration Protocol (DHCP) server through a Remote Messaging (Rm) port at the same time. Compared with the prior art, in the technical solution of the disclosure, the time for initiating the DHCP server by the terminal equipment (TE) is advanced and is identical to the time for initiating the wireless transmission connection establishment, thus the Um side and the Rm side can initiate the dial-up flow at the same time, and the time for waiting DHCP discover messages and the time for waiting the wireless connection establishment overlap, in this way, the purpose of shortening dial-up time and realizing quick dial-up is achieved.
摘要翻译：本公开提供了一种通过使用数据卡快速建立拨号连接的方法，其包括：当移动终端从计算机发起拨号连接时，通过统一消息发起无线连接建立的过程（Um）端口和通过远程消息（Rm）端口同时启动动态主机配置协议（DHCP）服务器的过程。与现有技术相比，在本公开的技术方案中，终端设备（TE）启动DHCP服务器的时间先进，与启动无线传输连接建立的时间相同，因此Um侧和 Rm侧可以同时启动拨号流程，等待DHCP发现消息的时间和等待无线连接建立的时间重叠，从而缩短拨号时间，实现快速拨号，实现了。

27. 发明申请

US20120190708A1 TARGETING NAD BIOSYNTHESIS IN BACTERIAL PATHOGENS 有权
标题翻译：在细菌病毒中靶向NAD生物合成
公开(公告)号：US20120190708A1
公开(公告)日：2012-07-26
申请号：US13383340
申请日：2010-07-12
申请人： Alexander Mackerell, JR. , Hong Zhang , Andrei Osterman , Rohit Kolhatkar
发明人： Alexander Mackerell, JR. , Hong Zhang , Andrei Osterman , Rohit Kolhatkar
IPC分类号： A61K31/4365 , A61P31/04 , A61K31/404 , A61K31/165 , A61K31/197
CPC分类号： C07C251/86
摘要： The emergence of multidrug-resistant pathogens necessitates the search for new antibiotics acting on previously unexplored targets. Nicotinate mononucleotide adenylyltransferase of the NadD family, an essential enzyme of NAD biosynthesis in most bacteria, was selected as a target for structure-based inhibitor development. To this end, the inventors have identified small molecule compounds that inhibit bacterial target enzymes by interacting with a novel inhibitory binding site on the enzyme while having no effect on functionally equivalent human enzymes.
摘要翻译：多药耐药病原体的出现需要寻找新的抗生素作用于以前未开发的靶标。 NadD家族的烟酸单核苷酸腺苷酰基转移酶是大多数细菌中NAD生物合成的必需酶，被选为基于结构的抑制剂发育的靶标。为此，本发明人已经鉴定了通过与酶上的新的抑制性结合位点相互作用而抑制细菌靶酶的小分子化合物，而对功能上等同的人酶没有影响。

28. 发明申请

US20120043850A1 ELECTRICAL ROTARY JOINT 审中-公开
标题翻译：电动旋转接头
公开(公告)号：US20120043850A1
公开(公告)日：2012-02-23
申请号：US13185749
申请日：2011-07-19
申请人： Boying B. ZHANG , Hong Zhang , Louis D. Violante
发明人： Boying B. ZHANG , Hong Zhang , Louis D. Violante
IPC分类号： H01R39/28
CPC分类号： H01R39/28 , F16H1/28 , F16H55/10
摘要： A simple planetary or epicyclic gear mechanism consists of a sun gear in the center, an internal or ring gear with a common axis with sun gear, and at least one planet gear. The planet gear is located between the sun gear and ring gear, and meshes with both the sun gear and the ring gear. If the ring gear is stationary, when sun gear rotates, the planet gear not only rotates about its axis, its axis also rotate around the axis of sun gear. In stead of employing the sliding motion between the ring and the brush in electrical slip ring, the current invention makes use of a plurality of conductive gears, particularly a planetary gear mechanism, to transfer electrical power, and/or signal(s) between relatively rotatable objects.
摘要翻译：一个简单的行星齿轮或行星齿轮机构由中心的太阳齿轮组成，具有与太阳齿轮的公共轴线的内部或齿圈以及至少一个行星齿轮组成。行星齿轮位于太阳齿轮和齿圈之间，并与太阳齿轮和齿圈啮合。如果环形齿轮是静止的，当太阳齿轮旋转时，行星齿轮不仅围绕其轴线旋转，其轴线也围绕太阳齿轮的轴线旋转。本发明不是在电滑环中使用环和电刷之间的滑动运动，而是利用多个导电齿轮，特别是行星齿轮机构来传递电功率和/或相对的信号可旋转物体。

29. 发明申请

US20110308499A1 METHOD AND DEVICE FOR OPERATING AN INTERNAL COMBUSTION ENGINE 有权
标题翻译：用于操作内燃机的方法和装置
公开(公告)号：US20110308499A1
公开(公告)日：2011-12-22
申请号：US13148349
申请日：2010-01-25
申请人： Uwe Jung , Gerd Rösel , Hong Zhang
发明人： Uwe Jung , Gerd Rösel , Hong Zhang
IPC分类号： F02M51/00
CPC分类号： F02D41/26 , F02D41/2425 , F02D41/2496
摘要： Each cylinder bank of the internal combustion engine is assigned in each case one injection event memory (EES), an injection determining process (EEP) and an injection execution process (EAP). In the respective injection determining process (EEP), desired injection events (EE) are determined for the associated cylinder bank. These injection events are stored in succession in the respectively associated injection event memory (EES). In the respective injection execution process (EAP), injection events (EE) are retrieved in succession from the associated injection event memory (EES) and executed in a sequence in which they were stored in the associated injection event memory (EES) by the associated injection determining process (EEP) (FIFO: first in first out). The in each case next injection event (EE) is executed only after the end of an execution of the in each case previously executed injection event (EE).
摘要翻译：在每种情况下，分配一个喷射事件存储器（EES），喷射确定过程（EEP）和喷射执行过程（EAP））内燃机的每个气缸组。在相应的喷射确定过程（EEP）中，为相关的气缸组确定期望的喷射事件（EE）。这些喷射事件被连续存储在分别关联的喷射事件存储器（EES）中。在相应的注射执行过程（EAP）中，从相关联的注入事件存储器（EES）连续地检索注入事件（EE），并以它们被相关联的注入事件存储器（EES）存储在相关联的注入事件存储器（EES）中的顺序执行）注入确定过程（EEP）（FIFO：先进先出）。在每种情况下，仅在每种情况下先前执行的注入事件（EE）的执行结束之后才执行下一个注入事件（EE）。

30. 发明授权

US08081307B2 Systems and methods for the inspection of stents 有权
标题翻译：检查支架的系统和方法
公开(公告)号：US08081307B2
公开(公告)日：2011-12-20
申请号：US12888337
申请日：2010-09-22
申请人： Ian Cameron , Andrew David Coppin Maw , Hong Zhang , Calden Wloka , Sidney Watterodt , Sang joon Park , Anthony S. Andreacchi , Yung-Ming Chen , Arnoldo M. Currlin , Antonio Garcia , Jason Van Sciver , Bryan D. Glenn
发明人： Ian Cameron , Andrew David Coppin Maw , Hong Zhang , Calden Wloka , Sidney Watterodt , Sang joon Park , Anthony S. Andreacchi , Yung-Ming Chen , Arnoldo M. Currlin , Antonio Garcia , Jason Van Sciver , Bryan D. Glenn
IPC分类号： G01N21/00
CPC分类号： G01N21/952 , A61F2/91 , A61F2/915 , A61F2002/91558 , A61F2002/91575 , A61F2230/0054 , A61F2240/008
摘要： A system and method for inspecting stents can involve an inspection camera to take an image of the stent and a computer system for analyzing the image to determine the presence of any coating defects. The determination can be made by masking out a portion of the stent, identifying deviations from a strut edge, and/or highlighting features protruding from a stent external boundary defining an outer diameter. The image can be taken after a focus feedback camera determines the position of the stent.
摘要翻译：用于检查支架的系统和方法可以包括检查相机以拍摄支架的图像和用于分析图像的计算机系统以确定是否存在任何涂层缺陷。可以通过掩盖支架的一部分，识别与支柱边缘的偏差和/或突出从限定外径的支架外部边界突出的特征来进行确定。在聚焦反馈相机确定支架的位置后，可以拍摄图像。

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