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21. 发明申请

US20060234338A1 Isomaltose synthase-knockout microorganism belonging eumycota 失效
标题翻译：异麦芽酮糖醇合成酶 - 敲除微生物属于真菌
公开(公告)号：US20060234338A1
公开(公告)日：2006-10-19
申请号：US10532064
申请日：2003-10-20
申请人： Kanako Suzuki , Norihiro Tsukagoshi
发明人： Kanako Suzuki , Norihiro Tsukagoshi
IPC分类号： C12P21/06 , C12N9/42 , C12N1/16 , C12N15/74
CPC分类号： C12N9/2451 , C12N9/2408 , C12N15/80 , C12Y204/01139 , C12Y302/0102
摘要： It is intended to provide a host microorganism whereby the expression of a gene encoding a target protein can be effectively elevated in the case of transferring the gene. It is also intended to provide a transformant whereby a target protein can be produced at a high efficiency. It is further intended to provide a production process whereby a target protein can be produced at a high productivity. A microorganism which belongs to Eumycota and lacks the major isomaltose synthase. A gene encoding a target protein is transferred into the microorganism to give a transformant. Then the transformant is cultured under conditions allowing the expression of the transferred gene to thereby produce the protein.
摘要翻译：旨在提供宿主微生物，其中在转移基因的情况下可以有效地提高编码靶蛋白的基因的表达。还旨在提供一种可以以高效率生产靶蛋白的转化体。进一步的目的是提供一种可以高生产率生产靶蛋白的生产方法。属于真菌纲的微生物，缺少主要的异麦芽糖合成酶。将编码靶蛋白的基因转移到微生物中，得到转化体。然后将转化体在允许转移的基因表达从而产生蛋白质的条件下培养。

22. 发明授权

US07857525B2 Optical connector 有权
标题翻译：光连接器
公开(公告)号：US07857525B2
公开(公告)日：2010-12-28
申请号：US11964749
申请日：2007-12-27
申请人： Kanako Suzuki , Yoshihisa Kato , Noribumi Shiina , Kazumasa Ohsono , Tomoyuki Nisio
发明人： Kanako Suzuki , Yoshihisa Kato , Noribumi Shiina , Kazumasa Ohsono , Tomoyuki Nisio
IPC分类号： G02B6/36 , G02B6/26 , G02B6/30 , G02B6/38 , G02B6/255
CPC分类号： G02B6/3846 , G02B6/255 , G02B6/382
摘要： An optical connector according to the present invention comprises a ferrule and a V-groove board connected to the ferrule, wherein a first optical fiber and a second optical fiber being butt jointed in a V-groove formed in the V-groove board so as to be interconnected; the second optical fiber is connected to the first optical fiber through a refractive index matching material of cross-link curing type applied to an end surface on the V-groove board side of the first optical fiber; and spaces are provided in the V-groove so as to relax stress loaded on the refractive index matching material of cross-link curing type.
摘要翻译：根据本发明的光连接器包括一个套圈和一个连接到套圈的V形槽板，其中第一光纤和第二光纤被对接在形成在V形槽板中的V形槽中，以便互相联系所述第二光纤通过施加到所述第一光纤的V槽板侧的端面的交联固化型的折射率匹配材料连接到所述第一光纤; 并且在V形槽中设置空间，以缓和负载在交联固化型折射率匹配材料上的应力。

23. 发明授权

US07805035B2 Forming method of refractive index matching film 有权
$Forming method of refractive index matching film$
标题翻译：折射率匹配薄膜的成型方法
公开(公告)号：US07805035B2
公开(公告)日：2010-09-28
申请号：US12021326
申请日：2008-01-29
申请人： Yoshihisa Kato , Kanako Suzuki
发明人： Yoshihisa Kato , Kanako Suzuki
IPC分类号： G02B6/32 , G02B6/00
CPC分类号： G02B6/3846 , G02B6/3855
摘要： A forming method of a refractive index matching film comprises steps: one end of an optical fiber is brought into contact with a liquid surface of a photo-curable refractive index matching solution; curing reaction light is made incident to the opposite end of the optical fiber and is emitted through the one end of the optical fiber so as to cure preliminarily the photo-curable refractive index matching solution in contact with the one end of the optical fiber; the curing reaction light is tentatively stopped; the one end of the optical fiber is separated from the liquid surface of the photo-curable refractive index matching solution; and the curing reaction light is made incident again from the opposite end of the optical fiber so as to cure the preliminarily cured photo-curable refractive index matching solution and form a refractive index matching film.
摘要翻译：折射率匹配膜的形成方法包括以下步骤：使光纤的一端与光固化型折射率匹配溶液的液面接触; 固化反应光入射到光纤的相对端，并通过光纤的一端发射，以便预先固化与光纤的一端接触的光固化折射率匹配溶液; 固化反应光暂时停止; 光纤的一端与光固化型折射率匹配溶液的液面分离; 并且使固化反应光从光纤的另一端重新入射，以固化预固化的光固化折射率匹配溶液并形成折射率匹配膜。

24. 发明授权

US07583877B2 Optical fiber, optical fiber connection structure and optical connector 失效
标题翻译：光纤，光纤连接结构和光纤连接器
公开(公告)号：US07583877B2
公开(公告)日：2009-09-01
申请号：US12068083
申请日：2008-02-01
申请人： Kanako Suzuki , Bing Yao , Kazumasa Ohsono , Yoshihisa Kato
发明人： Kanako Suzuki , Bing Yao , Kazumasa Ohsono , Yoshihisa Kato
IPC分类号： G02B6/02
CPC分类号： G02B6/02361 , G02B6/02376 , G02B6/02385 , G02B6/3806 , G02B6/381
摘要： An optical fiber includes a core, a clad having a plurality of air holes at a periphery of the core, and a hardening resin filled in a sealed portion at an end of the plurality of air holes. The hardening resin after hardening has a fill length of 7 mm to 8 mm. An optical fiber connection structure includes the optical fiber with an end face butt-connected to another optical fiber. An optical connector includes the optical fiber, and a ferrule to which the optical fiber is attached.
摘要翻译：光纤包括芯，在芯的周围具有多个气孔的包层，以及填充在多个气孔的端部的密封部分的硬化树脂。硬化后的硬化树脂的填充长度为7mm〜8mm。光纤连接结构包括具有与另一光纤对接的端面的光纤。光连接器包括光纤和光纤所附接的套圈。

25. 发明申请

US20080159696A1 Optical Connector 有权
标题翻译：光连接器
公开(公告)号：US20080159696A1
公开(公告)日：2008-07-03
申请号：US11964749
申请日：2007-12-27
申请人： Kanako Suzuki , Yoshihisa Kato , Noribumi Shiina , Kazumasa Ohsono , Tomoyuki Nisio
发明人： Kanako Suzuki , Yoshihisa Kato , Noribumi Shiina , Kazumasa Ohsono , Tomoyuki Nisio
IPC分类号： G02B6/38
CPC分类号： G02B6/3846 , G02B6/255 , G02B6/382
摘要： An optical connector according to the present invention comprises a ferrule and a V-groove board connected to the ferrule, wherein a first optical fiber and a second optical fiber being butt jointed in a V-groove formed in the V-groove board so as to be interconnected; the second optical fiber is connected to the first optical fiber through a refractive index matching material of cross-link curing type applied to an end surface on the V-groove board side of the first optical fiber; and spaces are provided in the V-groove so as to relax stress loaded on the refractive index matching material of cross-link curing type.
摘要翻译：根据本发明的光连接器包括一个套圈和一个连接到套圈的V形槽板，其中第一光纤和第二光纤被对接在形成在V形槽板中的V形槽中，以便互相联系所述第二光纤通过施加到所述第一光纤的V槽板侧的端面的交联固化型的折射率匹配材料连接到所述第一光纤; 并且在V形槽中设置空间，以缓和负载在交联固化型折射率匹配材料上的应力。

26. 发明申请

US20050170453A1 Modified promoter 有权
标题翻译：修饰的启动子
公开(公告)号：US20050170453A1
公开(公告)日：2005-08-04
申请号：US10505171
申请日：2003-02-28
申请人： Kanako Suzuki , Norihiro Tsukagoshi
发明人： Kanako Suzuki , Norihiro Tsukagoshi
IPC分类号： C12N15/09 , C12N1/15 , C12N15/80 , C12P21/02 , C12N1/16 , C12N15/74
CPC分类号： C12N15/80
摘要： It is intended to provide base sequences participating in the regulation of the expression of a promoter. It is also intended to modify a promoter based on the base sequence data to give a modified promoter having a high expression activity. Namely, a modified promoter constructed by inserting a first DNA fragment containing CCAATNNNNNN (a first base sequence) and a second DNA fragment containing CGGNNNNNNNNNGG (a second base sequence) into a promoter functioning in a filamentous fungus, wherein N in the base sequence denotes A (adenine), G (guanine), C(cytosine), or T (thymine).
摘要翻译：旨在提供参与启动子表达调节的碱基序列。还旨在基于碱基序列数据修饰启动子以产生具有高表达活性的修饰的启动子。即，通过将含有CCAATNNNNNN（第一碱基序列）的第一DNA片段和含有CGGNNNNNNNNNNGG（第二碱基序列）的第二DNA片段）插入到丝状真菌中起作用的启动子中构建的修饰启动子，其中碱基序列中的N表示A （腺嘌呤），G（鸟嘌呤），C（胞嘧啶）或T（胸腺嘧啶）。

27. 发明授权

US07341848B2 Isomaltose synthase-knockout microorganism belonging eumycota 失效
标题翻译：异麦芽酮糖醇合成酶 - 敲除微生物属于真菌
公开(公告)号：US07341848B2
公开(公告)日：2008-03-11
申请号：US10532064
申请日：2003-10-20
申请人： Kanako Suzuki , Norihiro Tsukagoshi
发明人： Kanako Suzuki , Norihiro Tsukagoshi
IPC分类号： C12P21/00 , C12N1/15
CPC分类号： C12N9/2451 , C12N9/2408 , C12N15/80 , C12Y204/01139 , C12Y302/0102
摘要： It is intended to provide a host microorganism whereby the expression of a gene encoding a target protein can be effectively elevated in the case of transferring the gene. It is also intended to provide a transformant whereby a target protein can be produced at a high efficiency. It is further intended to provide a production process whereby a target protein can be produced at a high productivity. A microorganism which belongs to Eumycota and lacks the major isomaltose synthase. A gene encoding a target protein is transferred into the microorganism to give a transformant. Then the transformant is cultured under conditions allowing the expression of the transferred gene to thereby produce the protein.
摘要翻译：旨在提供宿主微生物，其中在转移基因的情况下可以有效地提高编码靶蛋白的基因的表达。还旨在提供一种可以以高效率生产靶蛋白的转化体。进一步的目的是提供一种可以高生产率生产靶蛋白的生产方法。属于真菌纲的微生物，缺少主要的异麦芽糖合成酶。将编码靶蛋白的基因转移到微生物中，得到转化体。然后将转化体在允许转移的基因表达从而产生蛋白质的条件下培养。

28. 发明授权

US08648183B2 Modified promoter 有权
标题翻译：修饰的启动子
公开(公告)号：US08648183B2
公开(公告)日：2014-02-11
申请号：US10505171
申请日：2003-02-28
申请人： Kanako Suzuki , Norihiro Tsukagoshi
发明人： Kanako Suzuki , Norihiro Tsukagoshi
IPC分类号： C07H21/04 , G01N33/53 , C12P21/06 , C12N1/00
CPC分类号： C12N15/80
摘要： It is intended to provide base sequences participating in the regulation of the expression of a promoter. It is also intended to modify a promoter based on the base sequence data to give a modified promoter having a high expression activity. Namely, a modified promoter constructed by inserting a first DNA fragment containing CCAATNNNNNN (SEQ ID NO:1) (a first base sequence) and a second DNA fragment containing CGGNNNNNNNNNGG (SEQ ID NO:2) (a second base sequence) into a promoter functioning in a filamentous fungus, wherein N in the base sequence denotes A (adenine), G (guanine), C(cytosine), or T (thymine).
摘要翻译：旨在提供参与启动子表达调节的碱基序列。还旨在基于碱基序列数据修饰启动子以产生具有高表达活性的修饰的启动子。即，通过将含有CCAATNNNNNN（SEQ ID NO：1）（第一碱基序列）的第一DNA片段和含有CGGNNNNNNNNNNNGG（SEQ ID NO：2）（第二碱基序列）的第二DNA片段）（第二碱基序列）插入启动子构建的修饰启动子在丝状真菌中起作用，其中碱基序列中的N表示A（腺嘌呤），G（鸟嘌呤），C（胞嘧啶）或T（胸腺嘧啶）。

29. 发明申请

US20080304794A1 Optical connector 有权
标题翻译：光连接器
公开(公告)号：US20080304794A1
公开(公告)日：2008-12-11
申请号：US12000896
申请日：2007-12-18
申请人： Yoshihisa Kato , Kanako Suzuki
发明人： Yoshihisa Kato , Kanako Suzuki
IPC分类号： G02B6/36
CPC分类号： G02B6/3846 , G02B6/02314 , G02B6/3806 , G02B6/382 , G02B6/3858
摘要： An optical connector has a ferrule, an optical fiber connector disposed at an back end of the ferrule, an internal optical fiber inserted into the ferrule and the optical fiber connector, the internal optical fiber being adapted to butt-connect at a back end face thereof to an external optical fiber to be inserted into the optical fiber connector, and a refractive index matching body attached to the back end face of the internal optical fiber. The refractive index matching body has a cross-linked and hardened cross-linkable refractive index matching agent including a stress-strain relaxation agent.
摘要翻译：光连接器具有套圈，配置在套圈的后端的光纤连接器，插入套圈的内部光纤和光纤连接器，内部光纤适于在其后端面对接涉及插入到光纤连接器中的外部光纤，以及安装在内部光纤的后端面的折射率匹配体。折射率匹配体具有包含应力 - 应变松弛剂的交联且硬化的可交联折射率匹配剂。

30. 发明申请

US20080131061A1 FORMING METHOD OF REFRACTIVE INDEX MATCHING FILM 有权
标题翻译：折射指数匹配膜的形成方法
公开(公告)号：US20080131061A1
公开(公告)日：2008-06-05
申请号：US12021326
申请日：2008-01-29
申请人： Yoshihisa KATO , Kanako Suzuki
发明人： Yoshihisa KATO , Kanako Suzuki
IPC分类号： G02B6/255
CPC分类号： G02B6/3846 , G02B6/3855
摘要： A forming method of a refractive index matching film comprises steps: one end of an optical fiber is brought into contact with a liquid surface of a photo-curable refractive index matching solution; curing reaction light is made incident to the opposite end of the optical fiber and is emitted through the one end of the optical fiber so as to cure preliminarily the photo-curable refractive index matching solution in contact with the one end of the optical fiber; the curing reaction light is tentatively stopped; the one end of the optical fiber is separated from the liquid surface of the photo-curable refractive index matching solution; and the curing reaction light is made incident again from the opposite end of the optical fiber so as to cure the preliminarily cured photo-curable refractive index matching solution and form a refractive index matching film.
摘要翻译：折射率匹配膜的形成方法包括以下步骤：使光纤的一端与光固化型折射率匹配溶液的液面接触; 固化反应光入射到光纤的相对端，并通过光纤的一端发射，以便预先固化与光纤的一端接触的光固化折射率匹配溶液; 固化反应光暂时停止; 光纤的一端与光固化型折射率匹配溶液的液面分离; 并且使固化反应光从光纤的另一端重新入射，以固化预固化的光固化折射率匹配溶液并形成折射率匹配膜。

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