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21. 发明授权

US5619984A Dry powder inhalation device having a powder-loaded elongate carrier 失效
标题翻译：具有粉末加载的细长载体的干粉吸入装置
公开(公告)号：US5619984A
公开(公告)日：1997-04-15
申请号：US437291
申请日：1995-05-08
申请人： Peter D. Hodson , David K. Smith , David J. Velasquez , Anthony C. L. Wass
发明人： Peter D. Hodson , David K. Smith , David J. Velasquez , Anthony C. L. Wass
IPC分类号： A61K9/14 , A61K45/08 , A61K47/30 , A61M15/00 , A61M15/02 , A61M16/00 , A61P11/00 , B05D7/14 , B65D83/06
CPC分类号： A61M15/0045 , A61M15/0006 , A61M15/0016 , A61M15/0025 , A61M15/0028 , A61M15/0043 , A61M15/0048 , A61M15/0051 , A61M15/0055 , A61M15/0066 , A61M15/0078 , A61M15/0085 , A61M15/0091 , A61M15/02 , A61M2016/0024 , A61M2202/064 , A61M2205/8206
摘要： A dry powder inhalation device comprising a housing defining a chamber in communication with a patient port in the form of a mouthpiece or nasal adaptor, and an elongate carrier bearing a powdered medicament, the device being constructed and arranged such that areas of predetermined size of the elongate carrier may sequentially be exposed within the chamber, the device comprising one or more air inlets such that when a patient inhales through the patient port an air flow is established from the air inlet(s) to the patient port through the chamber such that particles of the powdered medicament of respirable size from said exposed area of the elongate carrier are entrained within the air flow.
摘要翻译：一种干粉吸入装置，其特征在于，包括壳体，所述壳体限定与所述口部或鼻部适配器形式的患者端口连通的室，以及承载有粉末状药物的细长载体，所述装置被构造和布置成使得预定尺寸的细长的载体可以顺序地在腔室内暴露，该装置包括一个或多个空气入口，使得当患者通过患者端口吸入时，通过腔室从空气入口到患者端口建立空气流，使得颗粒的来自所述细长载体的所述暴露区域的可吸入尺寸的粉末状药物被夹带在空气流中。

22. 发明授权

US5487378A Inhaler 失效
标题翻译：吸入器
公开(公告)号：US5487378A
公开(公告)日：1996-01-30
申请号：US78151
申请日：1993-10-04
申请人： Paul A. Robertson , Peter J. Houzego , Borge R. Jensen , Murray A. Creeke , Neil Emerton , Peter D. Hodson , Eric A. Baum
发明人： Paul A. Robertson , Peter J. Houzego , Borge R. Jensen , Murray A. Creeke , Neil Emerton , Peter D. Hodson , Eric A. Baum
IPC分类号： A61M15/00 , A61M16/00 , B05B17/00 , B05B17/06 , A61M11/00
CPC分类号： B05B17/0638 , A61M15/0015 , A61M15/0018 , A61M15/0065 , A61M15/0085 , B05B17/0661 , B05B17/0669 , B05B17/0676 , A61M2016/0024
摘要： An inhaler for dispensing droplets of liquid medicament to a patient comprising a body having a mouthpiece or nasal adaptor and a reservoir of liquid medicament in communication with an aerosol generator. The aerosol generator includes a chamber for the liquid medicament and a nozzle arrangement having a plurality of orifices. Means are provided for cyclically pressurizing the liquid medicament in the chamber such that liquid from the chamber is periodically expelled through the orifices of the nozzle arrangement as atomizer droplets of liquid medicament. Dosage control means are also provided for deactivating the aerosol generator after a predetermined time or after a predetermined volume of liquid medicament has been expelled from the chamber.
摘要翻译： PCT No.PCT / GB91 / 02250 Sec。 371日期：1993年10月4日 102（e）日期1993年10月4日PCT 1991年12月17日PCT PCT。公开号WO92 / 11050 PCT 日期1992年7月9日。一种吸入器，用于将液体药物的液滴分配给患者，所述患者包括具有口部或鼻部适配器的主体以及与气溶胶发生器连通的液体药剂储存器。气溶胶发生器包括用于液体药物的腔室和具有多个孔口的喷嘴装置。提供了用于对腔室中的液体药物循环加压的装置，使得来自腔室的液体通过喷嘴装置的孔周期性地排出，作为液体药物的雾化器液滴。还提供了剂量控制装置，用于在预定时间之后或在预定体积的液体药物已经从腔室排出之后停用气溶胶发生器。

23. 发明授权

US5437271A Deagglomerators for dry powder inhalers 失效
标题翻译：干粉吸入器的分散体
公开(公告)号：US5437271A
公开(公告)日：1995-08-01
申请号：US220726
申请日：1994-03-31
申请人： Peter D. Hodson , David J. Greenleaf
发明人： Peter D. Hodson , David J. Greenleaf
IPC分类号： A61M11/00 , A61M15/00 , A61M16/20
CPC分类号： A61M15/0086 , A61M11/001 , A61M15/0016 , A61M15/009 , A61M15/0091 , A61M2202/064
摘要： A deagglomerator that defines a channel for passage of powder laden air, which channel changes its geometry in response to changing inhalation flow rate.
摘要翻译：一个解聚器，它定义了一个通道，用于通过载粉末的空气，该通道根据吸入流速的变化而改变其几何形状。

24. 发明授权

US5192548A Device 失效
标题翻译：设备
公开(公告)号：US5192548A
公开(公告)日：1993-03-09
申请号：US516327
申请日：1990-04-30
申请人： David J. Velasquez , Peter D. Hodson , Clyde D. Calhoun
发明人： David J. Velasquez , Peter D. Hodson , Clyde D. Calhoun
IPC分类号： A61J3/00 , A61J3/02 , A61K9/00 , A61L15/44 , A61M13/00 , A61M15/00 , A61M15/02
CPC分类号： A61K9/0075 , A61J3/00 , A61M15/0045 , A61M15/0051 , A61M15/02 , B29C65/18 , B29C66/81457 , B29C66/83413 , B29K2821/00 , B29L2031/7164 , B29L2031/753
摘要： A sheet material comprising discrete depressions which are at least partially filled with micronized medicament and which are useful as or in a drug delivery device. This sheet material is useful in devices which provide for aerosolization of the medicament, for delivery to a patient by inhalation.

25. 发明申请

US20150190593A1 POWDER FILLING PROCESSES 有权
标题翻译：粉末填充工艺
公开(公告)号：US20150190593A1
公开(公告)日：2015-07-09
申请号：US14662067
申请日：2015-03-18
申请人： Peter D. Hodson , Matthew J. Wilby
发明人： Peter D. Hodson , Matthew J. Wilby
IPC分类号： A61M15/00 , B65H18/28 , B05D1/40
CPC分类号： A61M15/005 , A61K9/0075 , A61M15/0051 , A61M2202/064 , B05D1/40 , B65H18/28
摘要： A method for filling a plurality of microdepressions in a major surface of a web with finely divided powder in which the web is fed continuously to and through a powder filling stage including a driven roller. A method of manufacturing an elongate carrier with microdepressions containing finely divided powder comprising steps filling a plurality of microdepressions in a major surface of a web as described, removing from upper surface of the web excess powder not filled within the microdepressions and remaining on areas of the surface between the depressions, and optionally slitting and/or cutting the web in width and/or length.
摘要翻译：一种用细粉末填充幅材的主表面上的多个微压缩物的方法，其中幅材被连续地供给到并通过包括从动辊的粉末填充阶段。一种制造细长载体的方法，其具有包含细粉末的微量压缩物，其包括如上所述填充幅材的主表面中的多个微压缩物的步骤，从未填充在微食品中的幅材过量粉末的上表面移除并保留在凹陷之间的表面，并且可选地在宽度和/或长度上切割和/或切割幅材。

26. 发明申请

US20130047985A1 DRY POWDER INHALER ASSEMBLY AND CONTAINERS 审中-公开
标题翻译：干粉收集器和集装箱
公开(公告)号：US20130047985A1
公开(公告)日：2013-02-28
申请号：US13642717
申请日：2011-04-21
申请人： David S. Harris , Matthew D. Allen , Amanda J. Fuller , Nicholas Harrison , Karl J. Hewson , Peter D. Hodson , Scott A. Lewis , Tom A. Oakley , Samantha A. Patterson , Simon J. Smith , Rachel V. Striebig , Adam J. Stuart
发明人： David S. Harris , Matthew D. Allen , Amanda J. Fuller , Nicholas Harrison , Karl J. Hewson , Peter D. Hodson , Scott A. Lewis , Tom A. Oakley , Samantha A. Patterson , Simon J. Smith , Rachel V. Striebig , Adam J. Stuart
IPC分类号： A61M15/00
CPC分类号： A61M15/0028 , A61M15/0021 , A61M15/0026 , A61M15/0036 , A61M15/0041 , A61M15/0043 , A61M2202/064 , A61M2205/6045 , A61M2206/16
摘要： The present disclosure provides dry powder inhalers, containers for carrying a dose of dry powder medicament particles for dry powder inhalers, and a hinge that, while enjoying broader applicability, may be used in such inhalers.
摘要翻译：本公开提供干粉吸入器，用于携带用于干粉吸入器的干粉药物颗粒剂量的容器，以及在这种吸入器中可以使用更广泛适用性的铰链。

27. 发明申请

US20100300437A1 MANUFACTURE OF METERED DOSE VALVE COMPONENTS 审中-公开
标题翻译：计量剂阀组件的制造
公开(公告)号：US20100300437A1
公开(公告)日：2010-12-02
申请号：US12599565
申请日：2008-03-28
申请人： Michael B. Sivigny , Peter D. Hodson
发明人： Michael B. Sivigny , Peter D. Hodson
IPC分类号： A61M15/00 , B22F3/12
CPC分类号： B22F3/1021 , A61M15/0065 , A61M15/009 , A61M2207/00 , B22F3/004 , B22F5/00 , B22F2301/35 , B22F2304/10 , B22F2998/10 , B65D83/48
摘要： Use of metal powder injection molding for the manufacture of a metal valve component, such as a valve stem or a valve body, of a metered dose dispensing valve for use in a medicinal pressurized metered dose dispenser, such as an inhaler.
摘要翻译：使用金属粉末注射成型用于制造用于药用加压计量剂量分配器（例如吸入器）的计量剂量分配阀的金属阀组件（例如阀杆或阀体）。

28. 发明授权

US06460537B1 Breath-actuated aerosol dispensers 失效
标题翻译：呼吸式气雾剂分配器
公开(公告)号：US06460537B1
公开(公告)日：2002-10-08
申请号：US09437047
申请日：1999-11-09
申请人： Andrew M. Bryant , Anthony C. L. Wass , Peter D. Hodson
发明人： Andrew M. Bryant , Anthony C. L. Wass , Peter D. Hodson
IPC分类号： A61M1100
CPC分类号： A61M15/0091 , A61M15/0081 , A61M15/009 , A61M15/0093
摘要： A dispenser for dispensing a product from a pressurized product container comprising a housing defining a user port and adapted to have a pressurized product container mounted therein, the pressurized product container having a dispensing valve movable relative to the container between an open and a closed position; the housing further comprising a rolling member comprising a vane, and two associated rolling surfaces, the rolling member being capable of rotation in contact with the rolling surfaces such that they translate in opposite directions relative to the rolling member in response to inhalation through the user port, the rolling member being rotatable between a locking position in which the rolling member directly or indirectly engages the pressurized product container or valve to maintain the valve in the closed position, and a release position in which the valve and the pressurized product container move relative to each other so that the valve moves to the open position to dispense product from the container and towards the user port.
摘要翻译：一种用于从加压产品容器分配产品的分配器，包括限定用户端口并适于安装在其中的加压产品容器的壳体，所述加压产品容器具有可在打开和关闭位置之间相对于容器移动的分配阀; 所述壳体还包括滚动构件，所述滚动构件包括叶片和两个相关联的滚动表面，所述滚动构件能够旋转地与所述滚动表面接触，使得所述滚动构件响应于通过所述用户端口的吸入而相对于所述滚动构件在相反方向上平移所述滚动构件可在锁定位置之间旋转，在所述锁定位置中，所述滚动构件直接或间接地接合所述加压产品容器或阀，以将所述阀保持在关闭位置;以及释放位置，其中所述阀和所述加压产品容器相对于彼此使得阀移动到打开位置以从容器和用户端口分配产品。

29. 发明授权

US5482032A Dry powder inhalers 失效
标题翻译：干粉吸入器
公开(公告)号：US5482032A
公开(公告)日：1996-01-09
申请号：US273898
申请日：1994-07-12
申请人： David K. Smith , Peter D. Hodson , Anthony C. L. Wass
发明人： David K. Smith , Peter D. Hodson , Anthony C. L. Wass
IPC分类号： A61M15/00
CPC分类号： A61M15/0045 , A61M15/0026 , A61M15/0051 , A61M15/0055 , A61M2202/064
摘要： The present invention relates to a device for dislodging powder carried on the surface of a flexible sheet material. The device incorporates a resettable impactor including a head for striking the sheet material, wherein the head comprises an elongate striking surface which is curved in both planes orthoganol to the plan of the sheet material.
摘要翻译：本发明涉及一种用于移动在柔性片材表面上承载的粉末的装置。该装置包括可复位冲击器，其包括用于冲击片材的头部，其中头部包括细长的打击表面，该突出表面在与平板材料的平面的正交面的两个平面中弯曲。

30. 发明授权

US5408994A Inhalation device 失效
标题翻译：吸入装置
公开(公告)号：US5408994A
公开(公告)日：1995-04-25
申请号：US50440
申请日：1993-05-11
申请人： Anthony C. L. Wass , Brian R. Law , Eric A. Baum , Peter D. Hodson
发明人： Anthony C. L. Wass , Brian R. Law , Eric A. Baum , Peter D. Hodson
IPC分类号： A61M11/00 , A61M15/00
CPC分类号： A61M15/0091 , A61M15/009
摘要： An inhalation device for administration of aerosolized medicament to the respiratory system of a patient comprising a housing defining a patient port and an air inlet, the housing containing means for dispensing a dose of aerosolized medicament, an inhalation-activatable triggering mechanism for initiating the dispensing means, and reset means. The triggering mechanism comprises a vane mounted for pivotable movement between closed and open positions, the vane being positioned within the patient port such that inhalation through the patient port generates an airflow from the air inlet to the patient port causing pivotable movement of the vane. The device further includes an activator component moveable between a restrained position and a dispensing position which movement causes dispensing of medicament from the dispensing means, the activator component being biased towards its dispensing position.
摘要翻译： PCT No.PCT / GB91 / 01983 Sec。 371日期：1993年5月11日 102（e）日期1993年5月11日PCT 1991年11月12日PCT PCT。公开号WO92 / 08509 日期：1992年5月29日。一种用于向患者的呼吸系统施用雾化药物的吸入装置，包括限定患者口和空气入口的壳体，所述壳体容纳装置用于分配雾化药剂的剂量，可吸入激活的触发用于启动分配装置的机构和复位装置。触发机构包括安装成用于在闭合位置和打开位置之间可枢转运动的叶片，叶片定位在患者端口内，使得通过患者端口的吸入产生从空气入口到患者端口的气流，引起叶片的可枢转运动。该装置还包括可在限制位置和分配位置之间移动的活化剂组件，该运动导致药物从分配装置分配，活化剂组分被偏向其分配位置。

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