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21. 发明申请

US20090053083A1 METHOD AND DEVICE FOR OPERATING AN ELECTRIC PERISTALTIC HOSE PUMP 有权
标题翻译：用于操作电气软管泵的方法和装置
公开(公告)号：US20090053083A1
公开(公告)日：2009-02-26
申请号：US12282544
申请日：2007-03-01
申请人： Pascal Kopperschmidt
发明人： Pascal Kopperschmidt
IPC分类号： F04B43/12
CPC分类号： A61M1/16 , F04B43/0081 , F04B43/12 , F04B51/00 , F04B2201/1203 , F04B2207/70
摘要： The invention relates to a method and to a device for operating an electric peristaltic hose pump, in particular a hose pump for transporting fluids in medical-technical devices, in particular extracorporeal blood treatment devices. In order to monitor the regular operation of a hose pump, the power consumption of the pump or a physical variable in correlation with the power consumption, in particular the pump flow, is monitored. The pump flow includes a periodically non-altering direct component which is superimposed on a periodically altering alternating component. In order to monitor the regular operation of the hose pump, the alternating component of the power consumption in relation to the direct component of the power consumption is monitored as whether it increases and/or decreases during blood treatment.
摘要翻译：本发明涉及一种用于操作电动蠕动软管泵的方法和装置，特别是用于在医疗技术装置中输送流体的软管泵，特别是体外血液处理装置。为了监测软管泵的常规操作，监测泵的功率消耗或与功率消耗特别是泵流量相关的物理变量。泵流包括周期性地不改变的直接分量，其被叠加在周期性变化的交替分量上。为了监视软管泵的常规操作，监测与功耗的直接分量相关的功率消耗的交替分量，以及在血液处理期间是否增加和/或减少。

22. 发明授权

US10744466B2 Method for blowing free a wetted hydrophobic filter, and device for carrying out the method 有权
公开(公告)号：US10744466B2
公开(公告)日：2020-08-18
申请号：US12085680
申请日：2006-07-14
申请人： Pascal Kopperschmidt
发明人： Pascal Kopperschmidt
IPC分类号： B01D35/14 , B01D35/143 , B01D65/10 , A61M1/36 , B01D65/02
摘要： A method for clearing a wetted hydrophobic filter includes a first step in which the air permeability of the hydrophobic filter is monitored, and a second step in which the hydrophobic filter is cleared by means of a connected air pump, if it is detected that the hydrophobic filter is clogged. An apparatus for performing this method includes a pressure sensor and an air pump connected to an air separation chamber via a conduit, and a control and monitoring unit configured to actuate the air pump in order to clear the hydrophobic filter.

23. 发明授权

US08715214B2 Method and device for filling a supply device of a therapy appliance 有权
标题翻译：用于填充治疗器具的供应装置的方法和装置
公开(公告)号：US08715214B2
公开(公告)日：2014-05-06
申请号：US12310137
申请日：2007-08-23
申请人： Pascal Kopperschmidt
发明人： Pascal Kopperschmidt
IPC分类号： A61M37/00
CPC分类号： A61M5/1452 , A61M1/3649 , A61M1/3672
摘要： A method is provided for the filling of a metering apparatus of a therapy device having an extracorporeal circuit with which the metering apparatus is in communication such that an agent can be infused into the extracorporeal circuit during the operation of the therapy device by means of the metering device. The method includes a step of diluting a concentrate located in the metering apparatus by taking up a diluting agent from the extracorporeal circuit.
摘要翻译：提供了一种用于填充具有体外回路的治疗装置的计量装置的方法，所述计量装置与计量装置连通，使得在治疗装置的操作期间可以通过计量将药剂输入到体外回路中设备。该方法包括通过从体外回路吸收稀释剂来稀释位于计量装置中的浓缩物的步骤。

24. 发明授权

US08617093B2 Method and device for monitoring a fluid system of an extracorporeal blood treatment device 有权
标题翻译：用于监测体外血液处理装置的流体系统的方法和装置
公开(公告)号：US08617093B2
公开(公告)日：2013-12-31
申请号：US13376650
申请日：2010-06-01
申请人： Pascal Kopperschmidt , Thomas Nuernberger
发明人： Pascal Kopperschmidt , Thomas Nuernberger
IPC分类号： A61M37/00
CPC分类号： A61M1/3627 , A61M1/3624 , A61M1/3639 , A61M1/3641 , A61M2205/18 , A61M2205/707
摘要： The present invention relates to a method and a device for monitoring a fluid system of an extracorporeal blood treatment device. In the method according to the present invention and the device according to the present invention, the pressure in a ventilation line branching off the venous drip chamber in the venous blood line is measured, a hydrophobic filter being disposed in the ventilation line. A fault in the fluid system is determined in the absence of pressure variations in the segment of the ventilation line remote from the venous drip chamber. The pressure variations in the ventilation line can be generated downstream of the hydrophobic filter by alternately ventilating the ventilation line that is closed downstream of the hydrophobic filter during blood treatment.
摘要翻译：本发明涉及用于监测体外血液处理装置的流体系统的方法和装置。在根据本发明的方法和根据本发明的装置中，测量在静脉血液管线中分流出静脉滴注室的通气管路中的压力，在通气管线中设置疏水性过滤器。在远离静脉滴注腔的通气管段的压力变化不存在的情况下，确定流体系统中的故障。在血液处理期间，通过在疏水性过滤器下游关闭的通气管交替通风，可以在疏水性过滤器的下游产生通气管路的压力变化。

25. 发明申请

US20120083726A1 METHOD AND DEVICE FOR MONITORING A FLUID SYSTEM OF AN EXTRACORPOREAL BLOOD TREATMENT DEVICE 有权
标题翻译：用于监测超临界血液治疗装置的流体系统的方法和装置
公开(公告)号：US20120083726A1
公开(公告)日：2012-04-05
申请号：US13376650
申请日：2010-06-01
申请人： Pascal Kopperschmidt , Thomas Nüenberger
发明人： Pascal Kopperschmidt , Thomas Nüenberger
IPC分类号： A61M1/34
CPC分类号： A61M1/3627 , A61M1/3624 , A61M1/3639 , A61M1/3641 , A61M2205/18 , A61M2205/707
摘要： The present invention relates to a method and a device for monitoring a fluid system of an extracorporeal blood treatment device. In the method according to the present invention and the device according to the present invention, the pressure in a ventilation line branching off the venous drip chamber in the venous blood line is measured, a hydrophobic filter being disposed in the ventilation line. A fault in the fluid system is determined in the absence of pressure variations in the segment of the ventilation line remote from the venous drip chamber. The pressure variations in the ventilation line can be generated downstream of the hydrophobic filter by alternately ventilating the ventilation line that is closed downstream of the hydrophobic filter during blood treatment.
摘要翻译：本发明涉及用于监测体外血液处理装置的流体系统的方法和装置。在根据本发明的方法和根据本发明的装置中，测量在静脉血液管线中分流出静脉滴注室的通气管路中的压力，在通气管线中设置疏水性过滤器。在远离静脉滴注腔的通气管段的压力变化不存在的情况下，确定流体系统中的故障。在血液处理期间，通过在疏水性过滤器下游关闭的通气管交替通风，可以在疏水性过滤器的下游产生通气管路的压力变化。

26. 发明申请

US20110178452A1 DEVICE FOR EXTRACORPOREAL BLOOD TREATMENT IN SINGLE-NEEDLE OPERATION MODE 有权
标题翻译：用于单针操作模式下提取血液治疗的装置
公开(公告)号：US20110178452A1
公开(公告)日：2011-07-21
申请号：US13122220
申请日：2009-09-29
申请人： Pascal Kopperschmidt
发明人： Pascal Kopperschmidt
IPC分类号： A61M1/00
CPC分类号： A61M1/30 , A61M1/1006 , A61M1/1039 , A61M1/1086 , A61M1/302 , A61M1/308 , A61M1/3603 , A61M2205/3334
摘要： A device for the extracorporal blood treatment in a single-needle operating mode includes means for delivering blood into, and means for delivering blood out of means for collecting blood, and a controller for setting the respective delivery rates of the means for the delivery of blood. The operating mode of the means for delivering blood is continually switched between an arterial and a venous phase by the controller, wherein during the arterial phase the delivery rate Qb of the means for delivering blood is greater than the delivery rate Qsn of the means for delivering blood such that blood may be withdrawn from the patient during the arterial phase, and during the venous phase the delivery rate Qb is smaller than the delivery rate Qsn such that blood may be administered to the patient during the venous phase.
摘要翻译：用于以单针操作模式进行体外血液处理的装置包括用于将血液输送到用于收集血液的装置中的装置和用于输送血液的装置，以及用于设定用于输送血液的装置的各自输送速率的控制器。用于输送血液的装置的操作模式由控制器在动脉和静脉期之间连续切换，其中在动脉期期间，用于输送血液的装置的输送速率Qb大于用于输送的装置的输送速率Qsn 血液，使得血液可以在动脉期期间从患者中取出，并且在静脉期期间，输送速率Qb小于输送速率Qsn，使得可以在静脉期期间向患者施用血液。

27. 发明申请

US20100004579A1 METHOD AND DEVICE FOR FILLING A SUPPLY DEVICE OF A THERAPY APPLIANCE 有权
标题翻译：用于填充治疗装置的供应装置的方法和装置
公开(公告)号：US20100004579A1
公开(公告)日：2010-01-07
申请号：US12310137
申请日：2007-08-23
申请人： Pascal Kopperschmidt
发明人： Pascal Kopperschmidt
IPC分类号： A61M1/14
CPC分类号： A61M5/1452 , A61M1/3649 , A61M1/3672
摘要： The invention relates to a method for the filling of a metering apparatus of a therapy device having an extracorporeal circuit with which the metering apparatus is in communication such that an agent can be infused into the extracorporeal circuit during the operation of the therapy device by means of the metering device, with the method comprising the step of the dilution of a concentrate located in the metering apparatus, wherein the dilution of the concentrate located in the metering apparatus takes place in that the metering apparatus takes up the diluting agent from the extracorporeal circuit in the condition connected to the extracorporeal circuit.
摘要翻译：本发明涉及一种用于填充具有体外回路的治疗装置的计量装置的方法，所述计量装置与所述计量装置连通，使得在治疗装置的操作期间可以通过以下方式将试剂注入体外回路中：计量装置，其方法包括稀释位于计量装置中的浓缩物的步骤，其中位于计量装置中的浓缩物的稀释发生在于计量装置从体外循环中吸收稀释剂条件连接到体外电路。

28. 发明授权

US11376353B2 Method for regulating the supply of substituate during extracorporeal blood treatment and extracorporeal blood treatment device comprising a unit for regulating the supply of substituate 有权
公开(公告)号：US11376353B2
公开(公告)日：2022-07-05
申请号：US13512133
申请日：2010-11-16
申请人： Pascal Kopperschmidt , Alfred Gagel
发明人： Pascal Kopperschmidt , Alfred Gagel
IPC分类号： B01D61/32 , B01D61/28 , B01D61/24 , A61M1/16 , A61M1/36 , A61M1/34
摘要： The present invention relates to a method for regulating supply of substituate in an extracorporeal blood treatment with an extracorporeal blood treatment apparatus comprising a dialyzer divided by a semipermeable membrane into a blood chamber and a dialyzing fluid chamber and a device for supplying substituate. Moreover, the present invention relates to an extracorporeal blood treatment apparatus having a device for regulating supply of substituate. Regulation of supply of substituate in the extracorporeal blood treatment takes place as a function of the rheological loading of the dialyzer. To regulate supply of substituate during extracorporeal blood treatment, rheological loading of the dialyzer is determined from transmembrane pressure on the dialyzer and flow resistance of the dialyzer and substituate rate is increased or reduced according to the loading. The selection of dialyzer parameters or blood parameters is therefore no longer necessary and the distinction between pre-dilution and post-dilution is also made obsolete.

29. 发明授权

US09233341B2 Device and method for inspecting a filter for an extracorporeal blood treatment device 有权
标题翻译：用于检查体外血液处理装置的过滤器的装置和方法
公开(公告)号：US09233341B2
公开(公告)日：2016-01-12
申请号：US13500930
申请日：2010-10-01
申请人： Pascal Kopperschmidt , Christoph Bocklet
发明人： Pascal Kopperschmidt , Christoph Bocklet
IPC分类号： B01D61/00 , B01D35/00 , G01N15/08 , B01D65/10 , A61M1/16 , B01D61/22
CPC分类号： B01D65/102 , A61M1/1656 , A61M1/1672 , A61M2205/3317 , A61M2205/705 , B01D61/22 , B01D65/10 , B01D65/104 , B01D2311/243
摘要： The present invention relates to devices and methods for inspecting filters for extracorporeal blood treatment devices, e.g., filters for filtering dialysis fluid. The inspection of the filter according to the present invention is based on the measurement of the flow potential before and after changing the fluid flow of an electrolytic fluid between a transversal flow through the semi-permeable membrane of the filter and a longitudinal flow along the semi-permeable membrane of the filter, or vice versa. Changing the flow direction of the electrolytic fluid results in a change to the conductivity proceeding from a base value P to a higher value P2 or a lower value P1, wherein the conductivity readjusts to the base value P after a certain time interval T1, T2. An improper state of the filter is determined on the basis of the change in conductivity after changing the flow direction of the electrolytic fluid.
摘要翻译：本发明涉及用于检查用于体外血液处理装置的过滤器的装置和方法，例如用于过滤透析液的过滤器。根据本发明的过滤器的检查是基于在通过过滤器的半透膜的横向流动和沿半过滤器的纵向流动改变电解液的流体流动之前和之后的流量的测量过滤器的不透水膜，反之亦然。改变电解液的流动方向导致从基值P向较高值P2或较低值P1开始的电导率的变化，其中在一定时间间隔T1，T2之后，电导率重新调整到基值P. 基于改变电解液流动方向后的电导率变化来确定过滤器的不正确状态。

30. 发明授权

US09132224B2 Device and method for detecting the direction of the flow of liquid through a dialyzer 有权
标题翻译：用于检测通过透析器的液体流动方向的装置和方法
公开(公告)号：US09132224B2
公开(公告)日：2015-09-15
申请号：US13813490
申请日：2011-07-29
申请人： Pascal Kopperschmidt
发明人： Pascal Kopperschmidt
IPC分类号： A61M1/16 , A61M1/36 , G01P13/02
CPC分类号： A61M1/3663 , A61M1/16 , A61M1/1617 , A61M1/367 , A61M2205/18 , A61M2205/3317 , A61M2205/3324 , A61M2205/3368 , A61M2205/50 , A61M2205/702 , G01P13/02
摘要： The present invention relates to a device and a method for detecting the direction of the fluid flow through a dialyzer, as well as an extracorporeal blood treatment apparatus which comprises a device for detecting the direction of the fluid flow through the dialyzer. The devices and methods according to the present invention are based on the change in a physical and/or chemical property, for example the substance concentration or the temperature, of a fluid flowing into the one chamber of the dialyzer and the measurement of the change in the physical and/or chemical property of the fluid flowing out of the one chamber of the dialyzer.
摘要翻译：本发明涉及一种用于检测通过透析器的流体流动的方向的装置和方法，以及包括用于检测通过透析器的流体流动的方向的装置的体外血液处理装置。根据本发明的装置和方法基于物理和/或化学特性的变化，例如流入透析器的一个室的流体的物质浓度或温度的变化，以及从透析器的一个腔室流出的流体的物理和/或化学性质。

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