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1. 发明授权

US08617093B2 Method and device for monitoring a fluid system of an extracorporeal blood treatment device 有权
标题翻译：用于监测体外血液处理装置的流体系统的方法和装置
公开(公告)号：US08617093B2
公开(公告)日：2013-12-31
申请号：US13376650
申请日：2010-06-01
申请人： Pascal Kopperschmidt , Thomas Nuernberger
发明人： Pascal Kopperschmidt , Thomas Nuernberger
IPC分类号： A61M37/00
CPC分类号： A61M1/3627 , A61M1/3624 , A61M1/3639 , A61M1/3641 , A61M2205/18 , A61M2205/707
摘要： The present invention relates to a method and a device for monitoring a fluid system of an extracorporeal blood treatment device. In the method according to the present invention and the device according to the present invention, the pressure in a ventilation line branching off the venous drip chamber in the venous blood line is measured, a hydrophobic filter being disposed in the ventilation line. A fault in the fluid system is determined in the absence of pressure variations in the segment of the ventilation line remote from the venous drip chamber. The pressure variations in the ventilation line can be generated downstream of the hydrophobic filter by alternately ventilating the ventilation line that is closed downstream of the hydrophobic filter during blood treatment.
摘要翻译：本发明涉及用于监测体外血液处理装置的流体系统的方法和装置。在根据本发明的方法和根据本发明的装置中，测量在静脉血液管线中分流出静脉滴注室的通气管路中的压力，在通气管线中设置疏水性过滤器。在远离静脉滴注腔的通气管段的压力变化不存在的情况下，确定流体系统中的故障。在血液处理期间，通过在疏水性过滤器下游关闭的通气管交替通风，可以在疏水性过滤器的下游产生通气管路的压力变化。

2. 发明授权

US08315654B2 Extracorporeal blood treatment device and method for preparing blood treatment using an extracorporeal blood treatment device 有权
标题翻译：体外血液处理装置及使用体外血液处理装置进行血液处理的方法
公开(公告)号：US08315654B2
公开(公告)日：2012-11-20
申请号：US12438775
申请日：2007-08-22
申请人： Klaus Balschat , Pascal Kopperschmidt , Reiner Spickermann
发明人： Klaus Balschat , Pascal Kopperschmidt , Reiner Spickermann
IPC分类号： H04W4/12
CPC分类号： A61M1/14 , A61M1/16 , A61M1/168 , A61M1/1682 , A61M1/34 , A61M1/3643 , A61M1/3644 , A61M2205/3553 , A61M2205/3584 , A61M2205/50 , A61M2205/502 , A61M2205/60 , A61M2205/70
摘要： The present invention relates to an extracorporeal blood treatment device comprising a treatment unit and a device for controlling the treatment unit for preparing and carrying out the blood treatment. The blood treatment device also comprises an internal communication unit for communicating with an external communication unit. In order to the prepare the device blood treatment, the patient sends an initiation code by means of an external communication unit to the internal communication device. Routines required for preparing the blood treatment are then started. One main advantage is that the patient, for example during home dialysis, does not need to be present when the device is preparing for dialysis and the dialysis preparation can be started when the patient thinks of returning home in time for the beginning of the preparation phase.
摘要翻译：本发明涉及一种体外血液处理装置，其包括处理单元和用于控制用于制备和进行血液处理的处理单元的装置。血液处理装置还包括用于与外部通信单元通信的内部通信单元。为了准备用于血液处理的装置，患者通过外部通信单元向内部通信装置发送启动代码。然后开始准备血液处理所需的程序。一个主要的优点是，例如在家庭透析期间，当设备准备透析时，患者不需要存在患者，并且当患者认为在准备阶段开始时及时回家时可以开始透析准备。

3. 发明授权

US08177736B2 Device and method for monitoring access to a patient, in particular access to vessels during extracorporeal blood treatment 有权
标题翻译：用于监测对患者的访问的装置和方法，特别是在体外血液处理期间进入血管的装置和方法
公开(公告)号：US08177736B2
公开(公告)日：2012-05-15
申请号：US12282568
申请日：2006-12-08
申请人： Pascal Kopperschmidt
发明人： Pascal Kopperschmidt
IPC分类号： A61M37/00 , A61M1/00 , A41F1/00 , A41F1/08 , A44B1/04 , A44B1/18 , A44B11/25 , A44B17/00 , B42F1/00 , F16D1/08 , F16D3/80 , F16L17/00
CPC分类号： A61M1/3653 , A61M1/3655 , A61M1/3656 , A61M1/3659 , A61M5/1418 , A61M2205/18 , Y10T24/3439 , Y10T24/44 , Y10T24/44538 , Y10T403/22
摘要： The invention relates to a device and to a method for monitoring access to vessels during extracorporeal blood treatment. The invention forms a loop in the arterial and/or venous line and provides device for fixing a section of the line in a loop. When the line is stressed under tension, the loop contracts and the line finally kinks. The modification of the diameter of the line and the formation of a kink in the line leads to a rise of pressure in the line, which is monitored by a pressure monitoring device. If the pressure exceeds a predetermined threshold value, the aspirating cannula is in danger of slipping out of the vessel access or has partially or completely slipped out, thus allowing the threshold value to be determined for alarms.
摘要翻译：本发明涉及在体外血液处理期间监测血管通路的装置和方法。本发明在动脉和/或静脉线中形成环，并提供用于将线的一部分固定在环中的装置。当线路受到紧张的压力时，环路收缩，线路终于扭结。线的直径的改变和线中的扭结的形成导致管线中的压力升高，这由压力监测装置监测。如果压力超过预定的阈值，则抽吸插管有可能从容器进入或从部分或全部滑出，从而允许为报警确定阈值。

4. 发明授权

US07985196B2 Method for at least partially draining an extracorporeal blood flow and haemodialysis device for use with said method 有权
标题翻译：用于至少部分排出体外血流的方法和用于所述方法的血液透析装置
公开(公告)号：US07985196B2
公开(公告)日：2011-07-26
申请号：US12086593
申请日：2007-03-06
申请人： Pascal Kopperschmidt , Joachim Noack
发明人： Pascal Kopperschmidt , Joachim Noack
IPC分类号： A61M37/00 , C02F1/44
CPC分类号： A61M1/3643 , A61M1/1682 , A61M1/3644 , A61M1/3646 , A61M1/365 , A61M1/3652
摘要： A method and a hemodialysis machine provide for at least partial emptying of an extracorporeal blood circulation after patient blood in the circulation has been returned to the patient via an infusion liquid which displaces the blood. The method includes emptying at least a blood chamber of a hemodialyzer subdivided by a semipermeable membrane into the blood chamber and a dialysis fluid chamber without additionally connecting an arterial blood line and a venous blood line of the circulation to one another. The arterial blood line is actively or passively aerated at a first point and the venous blood line is actively or passively aerated at a second point. The infusion liquid is emptied through the membrane into the dialysis fluid chamber and then via a dialysis fluid discharge line. The method is operable by a control program that runs automatically without requiring any manual input after activation of the program.
摘要翻译：一种方法和血液透析机在循环中的患者血液已经通过置换血液的输注液体返回给患者之后，至少部分排空体外血液循环。所述方法包括将至少由半透膜细分的血液透析器的血液室排空到血液室中，以及透析液室，而不将动脉血管和循环的静脉血液线彼此连接。动脉血液线在第一点被主动地或被动地通气，并且静脉血液线在第二点被主动或被动地充气。将输液通过膜排空到透析液室中，然后通过透析液排出管。该方法可通过自动运行的控制程序进行操作，而不需要在激活程序之后进行任何手动输入。

5. 发明申请

US20100204633A1 METHOD FOR VERIFYING AND/OR MONITORING THE CORRECT FUNCTION OF A SUPPLY DEVICE 有权
标题翻译：用于验证和/或监控供应设备的正确功能的方法
公开(公告)号：US20100204633A1
公开(公告)日：2010-08-12
申请号：US12733702
申请日：2008-08-26
申请人： Pascal Kopperschmidt
发明人： Pascal Kopperschmidt
IPC分类号： A61M1/14 , G06F15/00 , G08B21/00
CPC分类号： A61M1/342 , A61M1/3639 , A61M1/3672 , A61M5/1452 , A61M5/16859 , A61M2205/14 , A61M2205/3331
摘要： The present invention relates to a method for checking and/or monitoring the correct operation of an adding device of a medical apparatus, wherein the medical apparatus includes an extracorporeal circuit with which the adding device is connected such that an agent can be introduced into the extracorporeal circuit by means of the adding device, the pressure loss in the extracorporeal circuit being measured and evaluated for checking and/or monitoring the correct operation of the adding device. In accordance with the invention, the adding device for this purpose generates an oscillating pressure course.
摘要翻译：本发明涉及一种用于检查和/或监视医疗装置的添加装置的正确操作的方法，其中所述医疗装置包括与所述添加装置连接的体外电路，使得可以将药剂引入体外通过加法装置对体外循环中的压力损失进行测量和评估，以检查和/或监视加法装置的正确操作。根据本发明，用于该目的的添加装置产生振荡压力进程。

6. 发明授权

US09724455B2 Dialysate flow control 有权
公开(公告)号：US09724455B2
公开(公告)日：2017-08-08
申请号：US13599028
申请日：2012-08-30
申请人： Pascal Kopperschmidt , Alfred Gagel
发明人： Pascal Kopperschmidt , Alfred Gagel
IPC分类号： A61M1/14 , A61M1/16 , A61M1/36
CPC分类号： A61M1/16 , A61M1/1605 , A61M1/1615 , A61M1/36 , A61M1/3609 , A61M2205/3317 , A61M2205/3324 , A61M2205/3368 , A61M2205/50
摘要： Method and apparatus for controlling the dialysate flow in a dialysis device. A change of the value of a control factor, caused by a variation of a property of the dialysate or of the blood or by a change of the dialysate flow, is determined in order to control the dialysate flow. The control factor is a measure for the exchange of substances via the dialyzer and thus the effectiveness of the dialyzer. If the change of the value of the control factor exceeds a limit, the dialysate flow is increased. On the other hand, the dialysate flow is reduced if the change of the value of the control factor falls short of the limit range.

7. 发明申请

US20110230812A1 METHOD AND DEVICE FOR RECOGNITION OF PARAVASAL BLEEDING 有权
标题翻译：用于识别PARAVASAL BLEEDING的方法和装置
公开(公告)号：US20110230812A1
公开(公告)日：2011-09-22
申请号：US13130116
申请日：2009-11-14
申请人： Pascal Kopperschmidt , Gross Malte , Spickermann Reiner
发明人： Pascal Kopperschmidt , Gross Malte , Spickermann Reiner
IPC分类号： A61M37/00 , A61B5/02
CPC分类号： A61B5/02042 , A61M1/3639 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M2205/18 , A61M2205/3331
摘要： A method and a device for recognition of paravasal bleeding upon a supplying of blood to a vascular access via a line and/or upon the removal of blood from a vascular access via a line, particularly paravasal bleeding during extra-corporeal blood treatment, such as for hemodialysis, hemofiltration or hemodiafiltration is provided. A device for extra-corporeal blood treatment, particularly for hemodialysis, hemofiltration or hemodiafiltration, comprising a device for recognition of paravasal bleeding is also provided. The method and the device are based on the change of arterial pressure in the arterial branch or the venous pressure in the venous branch of the extra-corporeal circuit being registered during the extra-corporeal blood treatment. If paravasal bleeding occurs during the blood treatment, the positive dynamic pressure on the line leading to the vascular access rises on the venous cannula during the extra-corporeal blood treatment, or the suction pressure on the line leaving the vascular access, such as the arterial cannula during extra-corporeal blood treatment, rises; that is, the suction pressure becomes more negative. The pressure rise begins moderately at first and then becomes increasingly greater. Decisive for the method and the device, therefore, is that pressure changes that come from a pressure level exhibiting a large difference from the reference value find stronger consideration than those that come from a pressure level that exhibits only a minor difference from the reference value.
摘要翻译：一种方法和装置，用于在通过管线向血管通路供血时和/或通过管线从血管通路中取出血液，特别是在体外血液处理期间特别是paravasal出血，例如用于血液透析，提供血液滤过或血液透析滤过。还提供了一种用于体外血液处理的装置，特别是用于血液透析，血液滤过或血液透析滤过的装置，其包括用于识别旁路出血的装置。该方法和装置基于在体外血液处理期间记录的动脉分支中的动脉压的变化或在体外循环的静脉分支中的静脉压。如果在血液治疗期间发生paravasal渗血，则导致血管通路的线上的积极动态压力在体外血液处理期间在静脉插管上升，或者离开血管通路的线路上的吸入压力，例如动脉套管在体外血液治疗中升高; 也就是说，吸入压力变得更负。首先压力上升开始适度，然后变得越来越大。因此，对于该方法和装置来说，与来自与参考值显示较大差异的压力水平的压力变化比从与参考值仅显示微小差异的压力水平的压力变化相比更强烈地考虑。

8. 发明申请

US20100323724A1 EXTRACORPOREAL BLOOD TREATMENT DEVICE AND METHOD FOR PREPARING BLOOD TREATMENT USING AN EXTRACORPOREAL BLOOD TREATMENT DEVICE 有权
标题翻译：超临界血液治疗装置及使用超临界血液治疗装置制备血液治疗的方法
公开(公告)号：US20100323724A1
公开(公告)日：2010-12-23
申请号：US12438775
申请日：2007-08-22
申请人： Klaus Balschat , Pascal Kopperschmidt , Reiner Spickermann
发明人： Klaus Balschat , Pascal Kopperschmidt , Reiner Spickermann
IPC分类号： H04W4/12 , H04B7/00
CPC分类号： A61M1/14 , A61M1/16 , A61M1/168 , A61M1/1682 , A61M1/34 , A61M1/3643 , A61M1/3644 , A61M2205/3553 , A61M2205/3584 , A61M2205/50 , A61M2205/502 , A61M2205/60 , A61M2205/70
摘要： The present invention relates to an extracorporeal blood treatment device comprising a treatment unit and a device for controlling the treatment unit for preparing and carrying out the blood treatment. The blood treatment device also comprises an internal communication unit for communicating with an external communication unit. In order to the prepare the device blood treatment, the patient sends an initiation code by means of an external communication unit to the internal communication device. Routines required for preparing the blood treatment are then started. One main advantage is that the patient, for example during home dialysis, does not need to be present when the device is preparing for dialysis and the dialysis preparation can be started when the patient thinks of returning home in time for the beginning of the preparation phase.
摘要翻译：本发明涉及一种体外血液处理装置，其包括处理单元和用于控制用于制备和进行血液处理的处理单元的装置。血液处理装置还包括用于与外部通信单元通信的内部通信单元。为了准备用于血液处理的装置，患者通过外部通信单元向内部通信装置发送启动代码。然后开始准备血液处理所需的程序。一个主要的优点是，例如在家庭透析期间，当设备正在进行透析时，患者不需要存在患者，并且当患者认为在准备阶段开始时及时回家时可以开始透析准备。

9. 发明申请

US20090306574A1 DEVICE AND METHOD FOR MONITORING ACCESS TO A PATIENT, IN PARTICULAR ACCESS TO VESSELS DURING EXTRACORPOREAL BLOOD TREATMENT 有权
标题翻译：用于监测患者在特发性血液治疗期间特异性获取血管的装置和方法
公开(公告)号：US20090306574A1
公开(公告)日：2009-12-10
申请号：US12282568
申请日：2006-12-08
申请人： Pascal Kopperschmidt
发明人： Pascal Kopperschmidt
IPC分类号： A61M39/12
CPC分类号： A61M1/3653 , A61M1/3655 , A61M1/3656 , A61M1/3659 , A61M5/1418 , A61M2205/18 , Y10T24/3439 , Y10T24/44 , Y10T24/44538 , Y10T403/22
摘要： The invention relates to a device and to a method for monitoring access to vessels during extracorporeal blood treatment. The invention forms a loop in the arterial and/or venous line and provides device for fixing a section of the line in a loop. When the line is stressed under tension, the loop contracts and the line finally kinks. The modification of the diameter of the line and the formation of a kink in the line leads to a rise of pressure in the line, which is monitored by a pressure monitoring device. If the pressure exceeds a predetermined threshold value, the aspirating cannula is in danger of slipping out of the vessel access or has partially or completely slipped out, thus allowing the threshold value to be determined for alarms.
摘要翻译：本发明涉及在体外血液处理期间监测血管通路的装置和方法。本发明在动脉和/或静脉线中形成环，并提供用于将线的一部分固定在环中的装置。当线路受到紧张的压力时，环路收缩，线路终于扭结。线的直径的改变和线中的扭结的形成导致管线中的压力升高，这由压力监测装置监测。如果压力超过预定的阈值，则抽吸插管有可能从容器进入或从部分或全部滑出，从而允许为报警确定阈值。

10. 发明申请

US20070108128A1 Method and device for the detection of disruptions of the blood flow in an extracorporeal blood circuit 有权
标题翻译：用于检测体外血液回路中血流中断的方法和装置
公开(公告)号：US20070108128A1
公开(公告)日：2007-05-17
申请号：US10580869
申请日：2004-09-11
申请人： Pascal Kopperschmidt , Malte Gross
发明人： Pascal Kopperschmidt , Malte Gross
IPC分类号： B01D61/32
CPC分类号： A61M1/3441 , A61M1/3434 , A61M1/3437 , A61M1/3609 , A61M1/3639 , A61M2230/207
摘要： A method and device that identify impairments of the blood flow in an extra-corporeal blood circuit during extracorporeal treatment of the blood using an extracorporeal haemodialysis device, where the phase angle of at least one harmonic oscillation of an oscillating pressure signal that propagates in the extracorporeal blood circuit is determined. Impairments of the blood flow are detected in the extracorporeal blood circuit based on a characteristic modification of the phase angle of at least one harmonic oscillation of the pressure signal. A temporal modification of the phase angle may be compared with a predefined threshold value and an impairment is detected if the value of the modification of the phase angle is greater than the predefined threshold value. The method and device permit an early identification of a coagulation of the blood that flows through the haemodialysis unit, so that countermeasures can be initiated promptly.
摘要翻译：一种方法和装置，其使用体外血液透析装置来识别血液体外处理期间体外血液回路中的血流的损伤，其中振荡压力信号的至少一次谐波振荡在体外传播的相位角确定血液回路。基于对压力信号的至少一次谐波振荡的相位角的特征修改，在体外血液回路中检测出血流的损伤。可以将相位角的时间修改与预定义的阈值进行比较，并且如果相位角的修改值大于预定阈值，则检测损伤。该方法和装置允许早期鉴定血液透析装置中血液的凝结，从而可以及时启动对策。

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