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21. 发明申请

US20090292125A1 PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES 有权
标题翻译：制备四氢喹啉衍生物的方法
公开(公告)号：US20090292125A1
公开(公告)日：2009-11-26
申请号：US12295618
申请日：2007-03-29
申请人： Masaki Okamoto , Akira Sakuragi , Yoshikazu Mori , Takeshi Hamada , Hitoshi Kubota , Yoshinori Nakamura , Takanori Higashijima , Norimitsu Hayashi
发明人： Masaki Okamoto , Akira Sakuragi , Yoshikazu Mori , Takeshi Hamada , Hitoshi Kubota , Yoshinori Nakamura , Takanori Higashijima , Norimitsu Hayashi
IPC分类号： C07D215/38
CPC分类号： C07D215/42 , C07D215/233
摘要： The present invention is to provide a process for preparing optically active tetrahydroquinoline derivatives which can be used for the treatment and/or prevention of diseases such as arteriosclerotic diseases, dyslipidemia and the like, and a process for preparing synthetic intermediates thereof.Specifically, (2R,4S)-2-ethyl-6-trifluoromethyl-1,2,3,4-tetrahydroquinolin-4-ylamine or a salt thereof is prepared with fewer steps without using an optical resolution, and the optically active tetrahydroquinoline derivatives are obtained from the amine compound.
摘要翻译：本发明提供一种可用于治疗和/或预防动脉硬化疾病，血脂异常等疾病的光学活性四氢喹啉衍生物的方法及其合成中间体的制备方法。具体地说，（2R，4S）-2-乙基-6-三氟甲基-1,2,3,4-四氢喹啉-4-基胺或其盐在不使用光学拆分的情况下以较少的步骤制备，并且光学活性的四氢喹啉衍生物由胺化合物得到。

22. 发明授权

US5944601A Coin processing device with adaptive storage 有权
标题翻译：具有自适应存储的硬币处理设备
公开(公告)号：US5944601A
公开(公告)日：1999-08-31
申请号：US227268
申请日：1999-01-08
申请人： Takahiro Hayashi , Yoshikazu Mori , Mitsugu Mikami
发明人： Takahiro Hayashi , Yoshikazu Mori , Mitsugu Mikami
IPC分类号： G07D1/00 , G07D9/06 , B65G57/03
CPC分类号： G07D1/00
摘要： In a coin processing device in accordance with the first aspect of the present invention, coin storage means (4) comprises a plurality of coin tubes (10, 11, 12, 13) which are separately formed, and linking means (30) which is formed for each one of the coin tubes (10, 11, 12, 13) and inter-links adjacent coin tubes. In a coin processing device in accordance with the second aspect of the present invention, coin storage means (64) comprises integrated type coin tubes (74) where a plurality of coin tubes are integrated into one unit, and adapter tubes (80, 81, 82) which are inserted in each one of the plurality of coin tubes (71, 72, 73) for changing the internal diameters thereof.
摘要翻译：在根据本发明的第一方面的硬币处理装置中，硬币存储装置（4）包括分开形成的多个硬币管（10,11,12,13）和连接装置（30）为每个硬币管（10,11,12,13）形成并且相互连接相邻的硬币管。在根据本发明第二方面的硬币处理装置中，硬币存储装置（64）包括集成式硬币管（74），其中多个硬币管集成在一个单元中，并且适配器管（80,81， 82）插入到多个硬币管（71,72,73）中的每一个中，用于改变其内径。

23. 发明授权

US5780677A Process for producing glutamine derivative 失效
标题翻译：谷氨酰胺衍生物的制备方法
公开(公告)号：US5780677A
公开(公告)日：1998-07-14
申请号：US833001
申请日：1997-04-04
申请人： Kazumi Amatsu , Yoshiyuki Yamada , Yoshikazu Mori , Shoichi Mizutaki , Masaji Kasai , Shinji Tomioka
发明人： Kazumi Amatsu , Yoshiyuki Yamada , Yoshikazu Mori , Shoichi Mizutaki , Masaji Kasai , Shinji Tomioka
IPC分类号： C07C231/14 , C07C231/02 , C07C231/10 , C07C237/22 , C07C229/00
CPC分类号： C07C231/02 , C07C231/10 , C07C237/22
摘要： N-chloroacetylglutamine is produced by reacting chloroacetyl chloride with an alkaline aqueous solution of glutamine the presence of a water-immiscible organic solvent, separating an aqueous layer by liquid-liquid separation, and crystallizing N-chloroacetyl-glutamine from the aqueous layer under acidic conditions. N-Chloroacetyl-glutamine useful as an intermediate for producing glycyl-L-glutamine which has higher stability than L-glutamine and is used as a component of an infusion solution can be obtained with high efficiency at low cost.
摘要翻译：通过氯乙酰氯与谷氨酰胺的碱性水溶液反应制备N-氯乙酰谷氨酰胺，与水不混溶的有机溶剂的存在，通过液 - 液分离分离水层，并在酸性条件下从水层中结晶N-氯乙酰基 - 谷氨酰胺。可以以低成本高效率地获得用作生产甘氨酰-L-谷氨酰胺的中间体的N-氯乙酰谷氨酰胺，其具有比L-谷氨酰胺更高的稳定性并用作输液的组分。

24. 发明申请

US20140142866A1 EVALUATING METHOD FOR PATTERN, EVALUATING METHOD FOR MULTICOMPONENT MATERIAL, EVALUATING PROGRAM, AND EVALUATING APPARATUS 审中-公开
标题翻译：模式评估方法，多组分材料评估方法，评估方案和评估装置
公开(公告)号：US20140142866A1
公开(公告)日：2014-05-22
申请号：US13806712
申请日：2012-05-31
申请人： Yoshikazu Mori , Keiichi Noda
发明人： Yoshikazu Mori , Keiichi Noda
IPC分类号： G01N33/15
CPC分类号： G01N33/15 , G01N30/8624 , G01N30/8665 , G01N30/8675 , G01N30/8679 , G01N30/8686 , G06K9/00543 , G16C20/20 , G16C20/70
摘要： Provided are a target FP preparing step, a target FP peak assigning step 149, a target FP peak feature value preparing step, a target FP type-2 preparing step, a target FP area segmentation feature value preparing step, a target FP feature value integrating step, and an evaluating step, to prepare target FP integrated feature values by integrating target FP peak feature values and target FP area segmentation feature values, and to compare and evaluate the target FP integrated feature values and reference FP integrated feature values that correspond to the target FP integrated feature values and are based on a plurality of reference FPs of multicomponent materials as evaluation criteria.
摘要翻译：提供了目标FP准备步骤，目标FP峰值分配步骤149，目标FP峰值特征值准备步骤，目标FP类型2准备步骤，目标FP区域分割特征值准备步骤，目标FP特征值积分步骤和评估步骤，通过集成目标FP峰值特征值和目标FP区域分割特征值来准备目标FP集成特征值，并比较和评估对应于FP的FP集成特征值和参考FP集成特征值目标FP集成特征值，并且基于作为评估标准的多组分材料的多个参考FP。

25. 发明申请

US20130237708A1 Optically Active Cyclic Alcohol Compound And Method For Preparing The Same 有权
标题翻译：光学活性环醇化合物及其制备方法
公开(公告)号：US20130237708A1
公开(公告)日：2013-09-12
申请号：US13747376
申请日：2013-01-22
申请人： Masaki Okamoto , Akira Sakuragi , Yoshikazu Mori , Muneki Kishida , Takanori Higashijima
发明人： Masaki Okamoto , Akira Sakuragi , Yoshikazu Mori , Muneki Kishida , Takanori Higashijima
IPC分类号： C07D215/233 , C07D401/04
CPC分类号： C07D215/233 , B01J31/0252 , B01J31/146 , B01J31/1805 , B01J31/2295 , B01J2231/64 , B01J2231/643 , B01J2531/821 , C07B53/00 , C07D215/22 , C07D401/04 , Y02P20/55
摘要： The present invention relates to a method for preparing an optically active cyclic alcohol compound represented by general formula [I]: [wherein R represents a hydrogen atom or a protecting group for amino group, and * represents an asymmetric carbon atom.] which comprises a step of subjecting a cyclic ketone compound represented by general formula [II]: [wherein R has the same meaning as defined above.] to asymmetric reduction (A) in the presence of an optically active oxazaborolidine compound and a boron hydride compound, or (B) in the presence of an asymmetric transition metal complex obtained from a transition metal compound and an asymmetric ligand and a hydrogen donor, and relates to said compound.
摘要翻译：本发明涉及一种由通式[I]表示的光学活性环状醇化合物的制备方法：[其中R表示氢原子或氨基保护基，*表示不对称碳原子]，其包含在光学活性的恶唑硼烷化合物和硼氢化合物的存在下，将不饱和还原（A）进行不饱和还原（A）的步骤：（其中R具有与上述定义相同的含义） B）在由过渡金属化合物和不对称配体和氢供体获得的不对称过渡金属络合物的存在下，涉及所述化合物。

26. 发明授权

US07972836B2 Method of enzymatic optical resolution of racemic 4-hydroxy-1,2,3,4-tetrahydroquinoline 有权
标题翻译：外消旋4-羟基-1,2,3,4-四氢喹啉的酶学光学拆分方法
公开(公告)号：US07972836B2
公开(公告)日：2011-07-05
申请号：US12083014
申请日：2006-10-04
申请人： Masaki Okamoto , Akira Sakuragi , Muneki Kishida , Yoshikazu Mori
发明人： Masaki Okamoto , Akira Sakuragi , Muneki Kishida , Yoshikazu Mori
IPC分类号： C12P41/00 , C12P17/18
CPC分类号： C07D215/233 , C07B51/00 , C07B53/00 , C07D215/06 , C07D215/08 , C07D401/04 , C12P17/12 , C12P41/005 , Y02P20/55
摘要： The present invention relates to a method for preparing an optically active 4-hydroxy-1,2,3,4-tetrahydroquinoline compound [I], which comprises the steps of: treating a racemic 4-hydroxy-1,2,3,4-tetrahydroquinoline compound represented by general formula [I]: [wherein R1 represents a hydrogen atom or a protecting group for amino group.] with an enzyme having an ability of selectively or preferentially acylating one enantiomer of the racemic compound [I] in the presence of an acyl donor; and if necessary, subjecting the reaction product to solvolysis.
摘要翻译：本发明涉及一种制备光学活性4-羟基-1,2,3,4-四氢喹啉化合物[I]的方法，其包括以下步骤：将外消旋的4-羟基-1,2,3,4 通式[I]表示的四氢喹啉化合物：[其中R1表示氢原子或氨基保护基]与具有选择性或优先酰化外消旋化合物[I]的一种对映异构体的能力的酶在存在下的酰基供体; 并且如果需要，使反应产物溶解。

27. 发明申请

US20090269821A1 Method for Preparing Optically Active 4-Hydroxy-1,2,3,4-Tetrahydroquinoline Compound 有权
标题翻译：光学活性4-羟基-1,2,3,4-四氢喹啉化合物的制备方法
公开(公告)号：US20090269821A1
公开(公告)日：2009-10-29
申请号：US12083014
申请日：2006-10-04
申请人： Masaki Okamoto , Akira Sakuragi , Muneki Kishida , Yoshikazu Mori
发明人： Masaki Okamoto , Akira Sakuragi , Muneki Kishida , Yoshikazu Mori
IPC分类号： C12P17/16 , C12P17/12
CPC分类号： C07D215/233 , C07B51/00 , C07B53/00 , C07D215/06 , C07D215/08 , C07D401/04 , C12P17/12 , C12P41/005 , Y02P20/55
摘要： The present invention relates to a method for preparing an optically active 4-hydroxy-1,2,3,4-tetrahydroquinoline compound [I], which comprises the steps of:treating a racemic 4-hydroxy-1,2,3,4-tetrahydroquinoline compound represented by general formula [I]: [wherein R1 represents a hydrogen atom or a protecting group for amino group.] with an enzyme having an ability of selectively or preferentially acylating one enantiomer of the racemic compound [I] in the presence of an acyl donor; and if necessary, subjecting the reaction product to solvolysis.
摘要翻译：本发明涉及一种制备光学活性4-羟基-1,2,3,4-四氢喹啉化合物[I]的方法，其包括以下步骤：将外消旋的4-羟基-1,2,3,4 通式[I]表示的四氢喹啉化合物：[其中R1表示氢原子或氨基保护基]与具有选择性或优先酰化外消旋化合物[I]的一种对映异构体的能力的酶在存在下的酰基供体; 并且如果需要，使反应产物溶解。

28. 发明授权

US07056219B2 Constant velocity joint boot 有权
标题翻译：恒速联轴器启动
公开(公告)号：US07056219B2
公开(公告)日：2006-06-06
申请号：US10682888
申请日：2003-10-14
申请人： Mayuki Toriumi , Yuji Furuta , Yoshikazu Mori
发明人： Mayuki Toriumi , Yuji Furuta , Yoshikazu Mori
IPC分类号： F16C1/26 , F16D3/84 , F16J3/04
CPC分类号： F16J3/042 , F16D3/845
摘要： In a boot including a larger cylindrical portion having a thick-walled portion and a thin-walled portion continuing smoothly in the circumferential direction on the inner peripheral surface, a ring groove coming full circle on the outer peripheral surface of the larger cylindrical portion is formed.Since shrinkage at the thick-walled portion can be prevented by the ring groove, and the ring groove is formed smoothly over the entire thick-walled portion and the thin-walled portion, there exists no varying point at which a stress generated when fastening with a fastening member suddenly changes.
摘要翻译：在具有厚壁部的较大的圆筒部和在内周面的圆周方向上平滑地延伸的薄壁部的靴子中，形成在大圆筒部的外周面上成为圆的环槽。由于可以通过环槽来防止厚壁部的收缩，并且在整个厚壁部分和薄壁部分上平滑地形成环形槽，所以不存在当紧固时产生的应力的变化点紧固件突然变化。

29. 发明授权

US06868955B2 Coin processing device 失效
标题翻译：硬币处理装置
公开(公告)号：US06868955B2
公开(公告)日：2005-03-22
申请号：US10001370
申请日：2001-10-25
申请人： Mitsugu Mikami , Yoshikazu Mori
发明人： Mitsugu Mikami , Yoshikazu Mori
IPC分类号： B42D15/10 , G06K17/00 , G06K19/00 , G07D9/00 , G07F1/06 , G07F5/24 , G07F7/02 , G07F7/08 , G07F9/10
CPC分类号： G07F5/24 , G07F1/06
摘要： A coin processing device, which ascertains genuine or counterfeit nature and denomination of inserted coins, accommodates coins that have been ascertained to be genuine according to denomination and pays out the accommodated coins via a coin pay-out slot according to amount of change, includes a coin-type IC card processor for ascertaining genuine or counterfeit nature of inserted coin-type IC cards, performing input and output of information into and from coin-type IC card that have been ascertained to be genuine and discharging the coin-type IC cards from the coin pay-out slot, whereby the coin processing device processes both the coins and coin-type IC cards.
摘要翻译：确定插入的硬币的正品或假冒性质和面额的硬币处理装置容纳根据面额被确定为真实的硬币，并且根据变化量经由硬币支付槽支付所容纳的硬币，包括硬币型IC卡处理器，用于确定插入的硬币型IC卡的正品或假冒性质，对已经确定为正品的硬币型IC卡进行信息的输入和输出，并将硬币型IC卡从硬币支付槽，由此硬币处理装置处理硬币和硬币型IC卡两者。

30. 发明授权

US06412619B1 Apparatus for processing paper money 有权
标题翻译：纸币处理设备
公开(公告)号：US06412619B1
公开(公告)日：2002-07-02
申请号：US09463335
申请日：2000-01-21
申请人： Yukio Ito , Yasuyuki Kodama , Mitsugu Mikami , Yoshikazu Mori
发明人： Yukio Ito , Yasuyuki Kodama , Mitsugu Mikami , Yoshikazu Mori
IPC分类号： G07F704
CPC分类号： G07F7/04 , G07D7/04 , G07F1/045
摘要： A bill identification device (20) is disposed in the vertical portion (6b) of a bill transporting route (6) that comprises a horizontal portion (6a) connected to a bill slot (3) and a vertical portion (6b) rising up substantially in a vertical direction from the downstream end of the horizontal portion (6a) whereby the drop in genuineness identification capability for an inserted bill can be prevented as much as possible even if a liquid such as salt water is poured into the bill slot (3).
摘要翻译：纸币识别装置（20）设置在纸币传送路径（6）的垂直部分（6b）中，包括连接到纸币槽（3）的水平部分（6a）和基本上升起的竖直部分（6b）在水平部分6a的下游端的垂直方向上，即使将诸如盐水的液体注入到纸币槽（3）中也能够尽可能地防止插入纸币的真实性识别能力下降，。

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