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21. 发明授权

US06841674B2 N-heterocyclic derivatives as NOS inhibitors 失效
标题翻译： N-杂环衍生物作为NOS抑制剂
公开(公告)号：US06841674B2
公开(公告)日：2005-01-11
申请号：US10122072
申请日：2002-04-12
申请人： Damian O. Arnaiz , John J. Baldwin , David D. Davey , James J. Devlin , Roland Ellwood Dolle, III , Shawn David Erickson , Kirk McMillan , Michael M. Morrissey , Michael H. J. Ohlmeyer , Gonghua Pan , Vidyadhar Madhav Paradkar , John Parkinson , Gary B. Phillips , Bin Ye , Zuchun Zhao
发明人： Damian O. Arnaiz , John J. Baldwin , David D. Davey , James J. Devlin , Roland Ellwood Dolle, III , Shawn David Erickson , Kirk McMillan , Michael M. Morrissey , Michael H. J. Ohlmeyer , Gonghua Pan , Vidyadhar Madhav Paradkar , John Parkinson , Gary B. Phillips , Bin Ye , Zuchun Zhao
IPC分类号： C07D403/14 , A61K31/506 , A61K31/5377 , A61K31/547 , A61P1/04 , A61P3/10 , A61P9/00 , A61P9/02 , A61P9/04 , A61P9/08 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/02 , A61P21/00 , A61P25/00 , A61P25/16 , A61P25/28 , A61P29/00 , A61P35/00 , A61P37/00 , A61P37/02 , A61P37/06 , A61P43/00 , C07D213/00 , C07D233/00 , C07D239/00 , C07D241/02 , C07D265/00 , C07D279/00 , C07D317/44 , C07D319/00 , C07D333/02 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D521/00
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08
摘要： N-Heterocyclic derivatives of the formula (I): are described herein, as well as other N-heterocycles, as inhibitors of nitric oxide synthase. Pharmaceutical compositions containing these compounds, methods of using these compounds as inhibitors of nitric oxide synthase and processes for synthesizing these compounds are also described herein.
摘要翻译：式（I）的N-杂环衍生物：本文描述以及其它N-杂环作为一氧化氮合酶的抑制剂。含有这些化合物的药物组合物，使用这些化合物作为一氧化氮合酶抑制剂的方法以及合成这些化合物的方法也在本文中描述。

22. 发明授权

US09008269B2 Method and apparatus for adjusting a field of view for exposure of an X-ray system, and an X-ray system 有权
标题翻译：用于调整用于X射线系统的曝光的视野的方法和装置以及X射线系统
公开(公告)号：US09008269B2
公开(公告)日：2015-04-14
申请号：US13598643
申请日：2012-08-30
申请人： Jian Wang , Bin Ye , Yannan Huang , Yonghui Han
发明人： Jian Wang , Bin Ye , Yannan Huang , Yonghui Han
IPC分类号： A61B6/08 , A61B6/00 , A61B6/06
CPC分类号： A61B6/52 , A61B6/06 , A61B6/08 , A61B6/4021 , A61B6/469 , A61B6/548
摘要： A method for adjusting a field of view for exposure of an X-ray system is provided. The method comprises: capturing an image of a patient on an examining table of the system by an image sensor, wherein the image sensor is placed at a predetermined position in the system; displaying the captured image on a display for selection of a region of interest or a point of interest by a user on the image; automatically determining a target position of an X-ray source in response to the selection of the region of interest or the point of interest on the image, wherein a desired field of view for exposure covering the region of interest or the point of interest is obtained when the X-ray source is located at the target position; and automatically locating the X-ray source at the target position in response to the determination of the target position.
摘要翻译：提供了一种用于调整用于X射线系统的曝光的视场的方法。该方法包括：通过图像传感器在系统的检查表上捕获患者的图像，其中图像传感器被放置在系统中的预定位置; 在显示器上显示所捕获的图像，以便在图像上选择用户感兴趣的区域或兴趣点; 响应于对图像上的感兴趣区域或兴趣点的选择，自动确定X射线源的目标位置，其中获得覆盖感兴趣区域或感兴趣点的曝光的期望视场当X射线源位于目标位置时; 并且响应于目标位置的确定，将X射线源自动定位在目标位置。

23. 发明申请

US20140242612A1 SYSTEM AND METHOD FOR INTEGRATION OF MOBILE DEVICE IMAGING WITH MICROCHIP ELISA 审中-公开
标题翻译：用MICROCHIP ELISA整合移动设备成像的系统和方法
公开(公告)号：US20140242612A1
公开(公告)日：2014-08-28
申请号：US14131853
申请日：2012-07-16
申请人： Shuqi Wang , Utkan Demirci , Bin Ye , Ragip Akbas
发明人： Shuqi Wang , Utkan Demirci , Bin Ye , Ragip Akbas
IPC分类号： G01N33/543 , G01N33/569 , G01N33/574
CPC分类号： G01N33/54386 , C12Q1/00 , G01N21/253 , G01N21/274 , G01N21/29 , G01N21/6452 , G01N21/78 , G01N33/53 , G01N33/56916 , G01N33/56972 , G01N33/57449 , G01N35/00
摘要： A system and method for analyzing a biomarker in a biological sample is provided. A biological sample is loaded onto a microchip and an enzyme-linked immunosorbent assay specific to the biomarker is performed on the microchip. A color image of the microchip is generated using a mobile device and a color intensity of a selected portion of the color image is determined. The color intensity is correlated with a biomarker concentration using a baseline curve calculation and the concentration of the biomarker is then reported.
摘要翻译：提供了用于分析生物样品中生物标志物的系统和方法。将生物样品加载到微芯片上，并在微芯片上进行对生物标志物特异性的酶联免疫吸附测定。使用移动设备生成微芯片的彩色图像，并且确定彩色图像的选定部分的颜色强度。使用基线曲线计算，颜色强度与生物标志物浓度相关，然后报告生物标志物的浓度。

24. 发明授权

US07549799B2 Radiograhic system 失效
标题翻译：无线电广播系统
公开(公告)号：US07549799B2
公开(公告)日：2009-06-23
申请号：US11966579
申请日：2007-12-28
申请人： Bin Ye
发明人： Bin Ye
IPC分类号： H01J31/49
CPC分类号： G03B42/04
摘要： A radiographic system (100) is provided wherein a single X-ray detector can be handled freely using a cable and which can prevent an operator or a patient from being troubled by the cable. The radiographic system (100) comprises a radiographic panel (5) configured to radiograph in two dimensions a radiation exposed to a subject and output radiation image data, a cable (6) for the supply of electric power to the radiographic panel and transfer of the radiation image data, a conveyance unit (8) for conveying the cable in a predetermined direction, a cable length adjusting unit (7) provided in the conveyance unit to adjust the length of the cable, and a movement control unit (72) configured to move the conveyance unit in accordance with a tilting direction of the cable from the cable length adjusting unit to the radiographic panel.
摘要翻译：提供了一种放射线照相系统（100），其中可以使用电缆自由地处理单个X射线检测器，并且可以防止操作者或患者受到电缆的困扰。射线照相系统（100）包括放射线照相面板（5），其配置成二维放射照射暴露于对象的辐射并输出放射线图像数据;电缆（6），用于向射线照相面板供应电力并传送辐射图像数据，用于沿预定方向传送电缆的传送单元（8），设置在传送单元中以调节电缆长度的电缆长度调节单元（7），以及移动控制单元（72）将输送单元按照电缆从电缆长度调节单元的倾斜方向移动到射线照相面板。

25. 发明申请

US20090099102A1 Ginkgolides in the Treatment and Prevention of Ovarian Cancer 审中-公开
标题翻译：银杏内酯治疗和预防卵巢癌
公开(公告)号：US20090099102A1
公开(公告)日：2009-04-16
申请号：US12084122
申请日：2006-10-24
申请人： Bin Ye , Daniel Cramer
发明人： Bin Ye , Daniel Cramer
IPC分类号： A61K31/7028 , A61K31/343 , A61P35/00
CPC分类号： A61K36/16 , A61K31/366
摘要： The present invention is directed to pharmaceutical compositions and nutritional supplements that contain large amount of ginkgolides, particularly ginkgolide A or B, and for which, the other components normally found in Ginkgo biloba extracts have been removed. The compositions may be administered to women to prevent or treat ovarian cancer, particularly non-mucinous ovarian cancer.
摘要翻译：本发明涉及含有大量银杏内酯，特别是银杏内酯A或B的药物组合物和营养补充剂，并且其中通常存在于银杏叶提取物中的其它组分已被除去。可以将组合物施用于妇女以预防或治疗卵巢癌，特别是非粘液性卵巢癌。

26. 发明申请

US20090086929A1 MEDICAL TABLE AND X-RAY IMAGING APPARATUS 有权
标题翻译：医疗表和X射线成像装置
公开(公告)号：US20090086929A1
公开(公告)日：2009-04-02
申请号：US12238093
申请日：2008-09-25
申请人： Bin Ye , Jiake Xu , Shaobo Gu , Feng Wang
发明人： Bin Ye , Jiake Xu , Shaobo Gu , Feng Wang
IPC分类号： G01C21/02 , A61B6/04 , A47C20/00 , G01J5/00
CPC分类号： A61B6/4283 , A61B6/0457 , A61B6/105 , G03B42/025
摘要： A medical table wherein a top board on which a patient is placed is supported by a base having an internal instrument so as to be movable parallel to the board surface, the medical table includes a detecting device that detects the possibility that a hand or fingers, which grip the top board, come in contact with the internal instrument during the movement of the top board or internal instrument, and a preventing device that prevents the movement of the top board or the internal instrument on the basis of a detection signal of the detecting device
摘要翻译：一种医用台，其中放置有患者的顶板由具有内部器具的基座支撑以平行于所述板表面移动，所述医用台包括检测装置，其检测手或手指的可能性，在顶板或内部仪器的运动过程中抓住顶板与内部仪器接触，防止装置根据检测的检测信号防止顶板或内部仪器的移动设备

27. 发明授权

US07288383B2 Eosinophil-derived neurotoxin as a marker for ovarian cancer 失效
标题翻译：嗜酸性粒细胞衍生的神经毒素作为卵巢癌的标志物
公开(公告)号：US07288383B2
公开(公告)日：2007-10-30
申请号：US10755854
申请日：2004-01-13
申请人： Bin Ye , Daniel W. Cramer , Samuel C. Mok
发明人： Bin Ye , Daniel W. Cramer , Samuel C. Mok
IPC分类号： G01N33/53 , C12Q1/00
CPC分类号： G01N33/57449 , C12Q1/6886 , C12Q2600/158 , G01N2333/922
摘要： The present invention is directed to methods of identifying women at increased risk of having ovarian cancer. Identification is based upon the extent to which biological samples derived from the women exhibit elevated levels of eosinophil-derived neurotoxin (EDN).
摘要翻译：本发明涉及确定具有卵巢癌风险增加的妇女的方法。识别是基于来自女性的生物样品的程度显示嗜酸性粒细胞衍生的神经毒素（EDN）水平升高。

28. 发明授权

US06849739B2 N-heterocyclic derivatives as NOS inhibitors 失效
公开(公告)号：US06849739B2
公开(公告)日：2005-02-01
申请号：US10121212
申请日：2002-04-12
申请人： Damian O. Arnaiz , John J. Baldwin , David D. Davey , James J. Devlin , Roland Ellwood Dolle, III , Shawn David Erickson , Kirk McMillan , Michael M. Morrissey , Michael H. J. Ohlmeyer , Gonghua Pan , Vidyadhar Madhav Paradkar , John Parkinson , Gary B. Phillips , Bin Ye , Zuchun Zhao
发明人： Damian O. Arnaiz , John J. Baldwin , David D. Davey , James J. Devlin , Roland Ellwood Dolle, III , Shawn David Erickson , Kirk McMillan , Michael M. Morrissey , Michael H. J. Ohlmeyer , Gonghua Pan , Vidyadhar Madhav Paradkar , John Parkinson , Gary B. Phillips , Bin Ye , Zuchun Zhao
IPC分类号： C07D403/14 , A61K31/506 , A61K31/5377 , A61K31/547 , A61P1/04 , A61P3/10 , A61P9/00 , A61P9/02 , A61P9/04 , A61P9/08 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/02 , A61P21/00 , A61P25/00 , A61P25/16 , A61P25/28 , A61P29/00 , A61P35/00 , A61P37/00 , A61P37/02 , A61P37/06 , A61P43/00 , C07D213/00 , C07D233/00 , C07D239/00 , C07D241/02 , C07D265/00 , C07D279/00 , C07D317/44 , C07D319/00 , C07D333/02 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D521/00 , C07D239/26 , C07D239/34 , C07D239/38
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08
摘要： N-Heterocyclic derivatives of the formula (I): are described herein, as well as other N-heterocycles, as inhibitors of nitric oxide synthase. Pharmaceutical compositions containing these compounds, methods of using these compounds as inhibitors of nitric oxide synthase and processes for synthesizing these compounds are also described herein.

29. 发明申请

US20140206679A1 HETEROCYCLIC PYRIDONE COMPOUND, AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF 有权
标题翻译：杂环吡啶类化合物及其中间体，制备方法及其用途
公开(公告)号：US20140206679A1
公开(公告)日：2014-07-24
申请号：US14124628
申请日：2012-05-28
申请人： Jianjun Cheng , Jihong Qin , Bin Ye
发明人： Jianjun Cheng , Jihong Qin , Bin Ye
IPC分类号： C07D513/04 , C07D498/04 , C07D471/04
CPC分类号： C07D513/04 , C07D471/04 , C07D498/04
摘要： The present invention relates to a heterocyclic pyridone compound represented by General Formula (I), where the heterocyclic pyridone compound is used as a tyrosine kinase inhibitor, and particularly a c-Met inhibitor. The present invention also relates to intermediates for preparing heterocyclic pyridone compound and a preparation method. The present invention further relates to a pharmaceutical composition containing the heterocyclic pyridone compound as an active ingredient, and a use of the pharmaceutical composition in treatment of diseases associated with tyrosine kinase c-Met, especially cancer associated with c-Met, as a medicament.
摘要翻译：本发明涉及由通式（I）表示的杂环吡啶酮化合物，其中杂环吡啶酮化合物用作酪氨酸激酶抑制剂，特别是c-Met抑制剂。本发明还涉及制备杂环吡啶酮化合物的中间体及其制备方法。本发明还涉及含有杂环吡啶酮化合物作为活性成分的药物组合物，以及该药物组合物用于治疗与酪氨酸激酶c-Met相关疾病，特别是与c-Met相关的癌症作为药物的用途。

30. 发明申请

US20100275219A1 SCSI PERSISTENT RESERVE MANAGEMENT 审中-公开
标题翻译： SCSI持续储备管理
公开(公告)号：US20100275219A1
公开(公告)日：2010-10-28
申请号：US12428831
申请日：2009-04-23
申请人： William G. Carlson , Ian MacQuarrie , Eric Wieder , Bin Ye
发明人： William G. Carlson , Ian MacQuarrie , Eric Wieder , Bin Ye
IPC分类号： G06F9/44 , G06F15/173
CPC分类号： H04L41/069 , G06F3/0605 , G06F3/0653 , G06F3/067
摘要： A network storage monitor system includes a device driver running on each of at least one first computer and a monitor application running on a second computer in communication with the each first computer. Each first computer also is in communication with a network storage switch and the network storage switch is in communication with at least one storage device. Each device driver sends to the second computer data regarding a storage event when the storage event is initiated by the respective first computer.
摘要翻译：网络存储监视器系统包括在至少一个第一计算机中的每一个上运行的设备驱动器和在与每个第一计算机通信的第二计算机上运行的监视应用程序。每个第一计算机还与网络存储交换机通信，网络存储交换机与至少一个存储设备通信。当存储事件由相应的第一计算机启动时，每个设备驱动程序向第二计算机发送关于存储事件的数据。

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