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21. 发明申请

US20080234588A1 Method and Apparatus for Determining Cardiac Performance in a Patient with a Conductance Catheter 有权
标题翻译：用于确定电导导管患者心脏性能的方法和装置
公开(公告)号：US20080234588A1
公开(公告)日：2008-09-25
申请号：US10568912
申请日：2004-09-03
申请人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce , Chia-Ling Wei
发明人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce , Chia-Ling Wei
IPC分类号： A61B5/0215 , A61B5/04
CPC分类号： A61B5/0538 , A61B5/02007 , A61B5/0215 , A61B5/029 , A61B5/053
摘要： An apparatus for determining cardiac performance in the patient involving a conductance catheter (12) for measuring conductance and blood volume in a heart chamber of the patient. The apparatus includes a processor (14) for determining instantaneous volume of the ventricle by applying a non-linear relationship between the measured conductance and the volume of blood in the heart chamber to identify mechanical strength of the chamber. The processor (14) is in communication with the conductance catheter (12).
摘要翻译：一种用于确定患者心脏性能的装置，涉及用于测量患者心室中的电导和血容量的导电导管（12）。该装置包括处理器（14），用于通过在测量的心室中的测量的电导和血液体积之间施加非线性关系来确定心室的瞬时体积，以识别腔室的机械强度。处理器（14）与导电导管（12）连通。

22. 发明授权

US10368776B2 Method and apparatus for determining cardiac performance in a patient with a conductance catheter 有权
公开(公告)号：US10368776B2
公开(公告)日：2019-08-06
申请号：US15816048
申请日：2017-11-17
申请人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce , Chia-Ling Wei
发明人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce , Chia-Ling Wei
IPC分类号： A61B5/053 , A61B5/02 , A61B5/0215 , A61B5/029
摘要： An apparatus for determining cardiac performance in the patient includes a plurality of electrodes adapted to be placed in the patient and in communication with a heart chamber of the patient for measuring conductance and blood volume in the heart chamber of the patient; and a processor for determining instantaneous volume of the ventricle based on measurement of complex admittance at a plurality of frequencies to identify mechanical strength of the chamber, the processor in communication with the electrodes. A method for determining cardiac performance in a patient.

23. 发明授权

US09820674B2 Method and apparatus for determining cardiac performance in a patient with a conductance catheter 有权
公开(公告)号：US09820674B2
公开(公告)日：2017-11-21
申请号：US15193931
申请日：2016-06-27
申请人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce , Chia-Ling Wei
发明人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce , Chia-Ling Wei
IPC分类号： A61B5/053 , A61B5/0215 , A61B5/029 , A61B5/02
CPC分类号： A61B5/0538 , A61B5/02007 , A61B5/0215 , A61B5/029 , A61B5/053
摘要： An apparatus for determining cardiac performance in the patient includes a plurality of electrodes adapted to be placed in the patient and in communication with a heart chamber of the patient for measuring conductance and blood volume in the heart chamber of the patient; and a processor for determining instantaneous volume of the ventricle based on measurement of complex admittance at a plurality of frequencies to identify mechanical strength of the chamber, the processor in communication with the electrodes. A method for determining cardiac performance in a patient.

24. 发明授权

US09380946B2 Method and apparatus for determining cardiac performance in a patient with a conductance catheter 有权
公开(公告)号：US09380946B2
公开(公告)日：2016-07-05
申请号：US14589603
申请日：2015-01-05
申请人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce , Chia-Ling Wei
发明人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce , Chia-Ling Wei
IPC分类号： A61N5/04 , A61B5/029 , A61B5/053 , A61B5/02 , A61B5/0215
CPC分类号： A61B5/0538 , A61B5/02007 , A61B5/0215 , A61B5/029 , A61B5/053
摘要： An apparatus for determining cardiac performance in the patient. The apparatus includes a conductance catheter for measuring conductance and blood volume in a heart chamber of the patient. The apparatus includes a processor for determining instantaneous volume of the ventricle by applying a non-linear relationship between the measured conductance and the volume of blood in the heart chamber to identify mechanical strength of the chamber. The processor is in communication with the conductance catheter. Methods for determining cardiac performance in a patient. Apparatuses for determining cardiac performance in a patient.

25. 发明授权

US08929976B2 Method and apparatus for determining cardiac performance in a patient with a conductance catheter 有权
标题翻译：用电导导管确定患者心脏性能的方法和装置
公开(公告)号：US08929976B2
公开(公告)日：2015-01-06
申请号：US13066201
申请日：2011-04-08
申请人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce , Chia-Ling Wei
发明人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce , Chia-Ling Wei
IPC分类号： A61N5/04 , A61B5/029 , A61B5/053
CPC分类号： A61B5/0538 , A61B5/02007 , A61B5/0215 , A61B5/029 , A61B5/053
摘要： An apparatus for determining cardiac performance in the patient. The apparatus includes a conductance catheter for measuring conductance and blood volume in a heart chamber of the patient. The apparatus includes a processor for determining instantaneous volume of the ventricle by applying a non-linear relationship between the measured conductance and the volume of blood in the heart chamber to identify mechanical strength of the chamber. The processor is in communication with the conductance catheter. Methods for determining cardiac performance in a patient. Apparatuses for determining cardiac performance in a patient.
摘要翻译：一种用于确定患者心脏性能的装置。该装置包括用于测量患者心室中的电导和血容量的导电导管。该装置包括一个处理器，用于通过在测量的心室中的测量的电导和血液体积之间施加非线性关系来确定心室的瞬时体积，以识别腔室的机械强度。处理器与导电导管连通。用于确定患者心脏性能的方法。用于确定患者心脏性能的装置。

26. 发明申请

US20160302691A1 Method and Apparatus for Determining Cardiac Performance in a Patient With a Conductance Catheter 审中-公开
标题翻译：用电导导管确定患者心脏性能的方法和装置
公开(公告)号：US20160302691A1
公开(公告)日：2016-10-20
申请号：US15193931
申请日：2016-06-27
申请人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce , Chia-Ling Wei
发明人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce , Chia-Ling Wei
IPC分类号： A61B5/053 , A61B5/0215 , A61B5/029
CPC分类号： A61B5/0538 , A61B5/02007 , A61B5/0215 , A61B5/029 , A61B5/053
摘要： An apparatus for determining cardiac performance in the patient includes a plurality of electrodes adapted to be placed in the patient and in communication with a heart chamber of the patient for measuring conductance and blood volume in the heart chamber of the patient; and a processor for determining instantaneous volume of the ventricle based on measurement of complex admittance at a plurality of frequencies to identify mechanical strength of the chamber, the processor in communication with the electrodes. A method for determining cardiac performance in a patient.
摘要翻译：用于确定患者心脏性能的装置包括多个电极，其适于放置在患者体内并与患者的心室连通，用于测量患者心室中的电导和血容量; 以及处理器，用于基于多个频率处的复合导纳的测量来确定心室的瞬时体积，以识别腔室的机械强度，处理器与电极连通。一种用于确定患者心脏性能的方法。

27. 发明申请

US20090210020A1 Method and Apparatus for Determining Cardiac Performance in a Patient 审中-公开
标题翻译：用于确定患者心脏性能的方法和装置
公开(公告)号：US20090210020A1
公开(公告)日：2009-08-20
申请号：US12086040
申请日：2006-12-14
申请人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce
发明人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce
IPC分类号： A61N1/368 , A61B5/02 , A61B5/0215 , A61N1/39
CPC分类号： A61N1/36514 , A61B5/0215 , A61B5/053 , A61B5/413 , A61N1/3627 , A61N1/36585 , A61N1/368 , A61N1/3684 , A61N1/3702 , A61N1/3962 , A61N1/3968
摘要： An apparatus for determining heart transplant rejection of a heart in a patient includes at least two electrodes adapted to be sewn into the heart that span the left ventricle. The apparatus includes a voltage generator adapted to be inserted in the patient which generates a voltage to the two electrodes and senses the resulting voltage from the two electrodes. A method for determining heart transplant rejection of a heart in a patient. A pacemaker for a patient (including bi-ventricular pacing and AICDs). The pacemaker includes an RV lead having four electrodes adapted to be inserted into the RV apex. The pacemaker includes a voltage generator which generates a voltage signal to the electrodes and senses the instantaneous voltage along the length of the RV and determines the real and imaginary components to remove the myocardial components of the septum and RV free wall to determine absolute RV blood volume. The pacemaker includes a battery connected to the voltage generator. The pacemaker includes a defibrillator connected to the battery. The pacemaker can also be a bi-ventricular pacemaker to restore RV and LV synchrony during contraction. A method for assisting a heart of a patient.
摘要翻译：用于确定患者心脏移植排斥反应的装置包括至少两个适于被缝合到穿过左心室的心脏中的电极。该装置包括适于插入到患者体内的电压发生器，该电压产生对两个电极的电压并感测来自两个电极的所得到的电压。用于确定患者心脏心脏移植排斥反应的方法。患者的起搏器（包括双心室起搏和AICD）。起搏器包括RV引线，其具有适于插入RV顶点的四个电极。起搏器包括电压发生器，其向电极产生电压信号并且感测沿着RV长度的瞬时电压，并且确定实部和虚部分量以去除隔膜和RV游离壁的心肌分量以确定绝对RV血容量。起搏器包括连接到电压发生器的电池。起搏器包括连接到电池的除颤器。起搏器也可以是一个双心室起搏器，用于在收缩期间恢复RV和LV同步。一种辅助患者心脏的方法。

28. 发明申请

US20180070851A1 Method and Apparatus for Determining Cardiac Performance in a Patient With a Conductance Catheter 审中-公开
公开(公告)号：US20180070851A1
公开(公告)日：2018-03-15
申请号：US15816048
申请日：2017-11-17
申请人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce , Chia-Ling Wei
发明人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce , Chia-Ling Wei
IPC分类号： A61B5/053 , A61B5/02 , A61B5/0215 , A61B5/029
CPC分类号： A61B5/0538 , A61B5/02007 , A61B5/0215 , A61B5/029 , A61B5/053
摘要： An apparatus for determining cardiac performance in the patient includes a plurality of electrodes adapted to be placed in the patient and in communication with a heart chamber of the patient for measuring conductance and blood volume in the heart chamber of the patient; and a processor for determining instantaneous volume of the ventricle based on measurement of complex admittance at a plurality of frequencies to identify mechanical strength of the chamber, the processor in communication with the electrodes. A method for determining cardiac performance in a patient.

29. 发明授权

US06494832B1 Multifrequency conductance catheter-based system and method to determine LV function in a patient 有权
标题翻译：多通道电导导管系统及方法确定患者的LV功能
公开(公告)号：US06494832B1
公开(公告)日：2002-12-17
申请号：US09649727
申请日：2000-08-28
申请人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce
发明人： Marc D. Feldman , Jonathan W. Valvano , John A. Pearce
IPC分类号： A61B500
CPC分类号： A61B5/0422 , A61B5/0215 , A61B5/0535 , A61B5/0538
摘要： An apparatus and method for determining cardiac performance in a patient. The apparatus includes a multifrequency conductance catheter for measuring instantaneous volume of a heart chamber with multifrequencies. The apparatus includes a mechanism for measuring instantaneous pressure of the heart chamber. The apparatus includes a mechanism for separating the multifrequencies. The apparatus includes a mechanism for signal processing the instantaneous volume and the pressure of the heart chamber to identify mechanical strength of the chamber and for automatically producing a plurality of desired waveforms at desired frequencies for the conductance catheter. The processing mechanism is connected to the pressure measuring mechanism, the separating mechanism and the volume measuring mechanism.
摘要翻译：一种用于确定患者心脏性能的装置和方法。该装置包括用于测量具有多个频率的心室的瞬时体积的多频电导导管。该装置包括用于测量心室的瞬时压力的机构。该装置包括用于分离多个频率的机构。该装置包括用于信号处理心室的瞬时体积和压力的机构，以识别腔室的机械强度，并用于自动产生用于导电导管的期望频率的多个期望波形。处理机构连接到压力测量机构，分离机构和体积测量机构。

30. 发明申请

US20110152661A1 Method and apparatus for identifying the viability of ischemic myocardium of a patient 审中-公开
标题翻译：用于鉴定患者缺血心肌的存活力的方法和装置
公开(公告)号：US20110152661A1
公开(公告)日：2011-06-23
申请号：US12924195
申请日：2010-09-22
申请人： Marc D. Feldman , Anil Tharian George Kottam , John Pearce , Jonathan Valvano , John Porterfield
发明人： Marc D. Feldman , Anil Tharian George Kottam , John Pearce , Jonathan Valvano , John Porterfield
IPC分类号： A61B5/0408 , A61B5/0402
CPC分类号： A61B5/0538 , A61B5/02 , A61B5/416 , A61B5/6883
摘要： A method for identifying the viability of ischemic myocardium of a patient. The method includes the steps of measuring in real-time the ischemic myocardium of a beating or non-beating heart. There is the step of determining in real-time whether the ischemic myocardium of the beating or non-beating heart is stunned or is nonviable. An apparatus for identifying the viability of ischemic myocardium of a patient's heart. The apparatus includes an electrode array having at least four electrodes for electrical communication with the heart which produces an array signal. The apparatus includes a processor portion in communication with the array which receives the array signal and determines in real-time whether the ischemic myocardium of the heart is stunned or is nonviable. An apparatus for analyzing living tissue. The apparatus includes an electrode array having at least four electrodes for electrical communication with the tissue which produces an array signal. The apparatus includes an admittance magnitude and phase detection circuit in communication with the array which receives the array signal from the array and produces a detection circuit signal corresponding to phase angle and magnitude of the array and signal. The apparatus includes a processor in communication with the detection circuit which receives the detection circuit signal and determines permittivity and conductivity of the tissue in real-time. A method for analyzing living tissue.
摘要翻译：用于鉴定患者缺血心肌的存活力的方法。该方法包括实时测量跳动或不跳动心脏的缺血心肌的步骤。实时确定殴打或非跳动心脏的缺血性心肌是否震惊或不可行的步骤。用于鉴定患者心脏缺血心肌的存活力的装置。该装置包括具有至少四个用于与心脏电连通的电极的电极阵列，其产生阵列信号。该装置包括与阵列通信的处理器部分，其接收阵列信号并实时确定心脏的缺血心肌是否震惊或不可行。一种用于分析活体组织的装置。该装置包括具有至少四个电极的电极阵列，用于与组织电连通，产生阵列信号。该装置包括与阵列通信的导纳幅度和相位检测电路，其接收来自阵列的阵列信号，并产生对应于阵列和信号的相位角和幅度的检测电路信号。该装置包括与检测电路通信的处理器，其接收检测电路信号并实时确定组织的介电常数和电导率。一种分析活体组织的方法。

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