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21. 发明授权

US09012477B2 Method of treating neuropathic pain 有权
标题翻译：治疗神经性疼痛的方法
公开(公告)号：US09012477B2
公开(公告)日：2015-04-21
申请号：US12652502
申请日：2010-01-05
申请人： Jie Zhang , Robert Lippert
发明人： Jie Zhang , Robert Lippert
IPC分类号： A61K31/445 , A61K31/245 , A61P23/02 , A61K31/24 , A61K9/70 , A61K31/167 , A61K47/32
CPC分类号： A61K31/24 , A61K9/7015 , A61K31/167 , A61K47/32 , A61K2300/00
摘要： A method for treating subjects experiencing neuropathic pain is provided. The method involves the application of a solid-forming local anesthetic formulation to a skin surface of the subject experiencing the neuropathic pain and then maintaining the formulation on the skin surface for a period of time sufficient to allow itself to transdermally deliver the local anesthetic to the subject thereby providing relief from the neuropathic pain within about 45 minutes.
摘要翻译：提供了治疗经历神经性疼痛的受试者的方法。该方法涉及将固体形成局部麻醉剂制剂施用于经历神经性疼痛的受试者的皮肤表面，然后将制剂保持在皮肤表面上足以允许其自身将局部麻醉剂递送至从而在约45分钟内提供神经性疼痛的缓解。

22. 发明授权

US08836448B2 Magnetic interface circuit 有权
标题翻译：磁接口电路
公开(公告)号：US08836448B2
公开(公告)日：2014-09-16
申请号：US13157375
申请日：2011-06-10
申请人： Jie Zhang , Yueh-Shan Shih
发明人： Jie Zhang , Yueh-Shan Shih
IPC分类号： H03H7/09 , H01R12/50
CPC分类号： H03H7/09 , H01R23/688
摘要： A noise filtering magnetic interface circuit used for an electrical connector is provided. The magnetic interface circuit includes a number of signal channels and a capacitor (40). Each channel has a transformer (10) and a 3-wire common mode choke (20). The transformer has a first winding (100) connected and a second winding (110), the first winding having two opposite outputs, the second winding having two outputs and a center tap (111). The 3-wire common mode choke has a center winding (220) and two outer windings (210, 230), the center winding having a first output connected to the center tap of the second winding and a second output opposite to the first output, the two outer windings being respectively connected to the two outputs of the second winding. The capacitor has a first pole connected to the second outputs of the center windings of the channels and an opposite second pole connected to a ground.
摘要翻译：提供了一种用于电连接器的噪声滤波磁接口电路。磁接口电路包括多个信号通道和电容器（40）。每个通道都有一个变压器（10）和一个3线共模扼流圈（20）。变压器具有连接的第一绕组（100）和第二绕组（110），第一绕组具有两个相对的输出端，第二绕组具有两个输出端和中心抽头（111）。 3线共模扼流圈具有中心绕组（220）和两个外部绕组（210,230），中心绕组具有连接到第二绕组的中心抽头的第一输出端和与第一输出端相反的第二输出端，两个外绕组分别连接到第二绕组的两个输出端。电容器具有连接到通道的中心绕组的第二输出的第一极和连接到地的相对的第二极。

23. 发明授权

US08735422B2 Cationic pharmaceutically active ingredient containing composition, and methods for manufacturing and using 有权
标题翻译：含阳离子药物活性成分的组合物，以及制造和使用方法
公开(公告)号：US08735422B2
公开(公告)日：2014-05-27
申请号：US12701367
申请日：2010-02-05
申请人： James A. Roszell , Jie Zhang
发明人： James A. Roszell , Jie Zhang
IPC分类号： A61K31/44
CPC分类号： A61K47/32 , A61K9/0014 , A61K31/437
摘要： A cationic pharmaceutically active ingredient containing composition is provided. The composition includes a cationic pharmaceutically active ingredient, a hydrophobic polymer/hydrophilic polymer adduct comprising a poly(vinylpyrrolidone/alkylene) polymer and a polymer comprising carboxylic acid groups, hydroxyl groups, or a mixture of carboxylic acid groups and hydroxyl groups, a compatibilizing amount of a long chain organic acid having a carbon chain of at least 8 carbon atoms, and at least about 50 wt. % water.
摘要翻译：提供了含有阳离子药物活性成分的组合物。该组合物包括阳离子药物活性成分，包含聚（乙烯基吡咯烷酮/亚烷基）聚合物的疏水聚合物/亲水性聚合物加合物和包含羧酸基团，羟基或羧酸基团和羟基的混合物的聚合物，相容量具有至少8个碳原子的碳链的长链有机酸和至少约50重量％％水。

24. 发明授权

US08658260B2 Laser-induced backside annealing using fluid absorber 有权
标题翻译：使用流体吸收器的激光诱导背面退火
公开(公告)号：US08658260B2
公开(公告)日：2014-02-25
申请号：US13453518
申请日：2012-04-23
申请人： Jie Zhang
发明人： Jie Zhang
IPC分类号： B05D3/02 , B05D3/00
CPC分类号： H05K3/02 , H01L31/022466 , H01L31/1884 , H05K3/1283 , H05K2201/0108 , H05K2201/0326 , H05K2203/0776 , H05K2203/107 , H05K2203/1581 , Y02E10/50
摘要： A coating material containing metal oxide is applied to one side of a substrate, both coating and substrate being transparent to visible light. An absorber material is placed in heat transfer proximity to the coating and a laser beam is transmitted through the substrate and through the coating to strike the absorber material at the interface between coating and absorber. The absorber material absorbs optical energy from the laser beam causing the material to heat. Heat from the absorber propagates to the coating to heat a localized region, causing the coating material to anneal. If desired, the coating material can include a doping material that fuses into the coating during annealing.
摘要翻译：将含有金属氧化物的涂料施加到基材的一侧，涂层和基材对可见光都是透明的。将吸收材料置于热传递附近的涂层上，并且激光束透射穿过基底并穿过涂层以在涂层和吸收体之间的界面处撞击吸收体材料。吸收材料从激光束吸收光能使材料发热。来自吸收器的热量传播到涂层以加热局部区域，导致涂层材料退火。如果需要，涂层材料可以包括在退火期间熔化到涂层中的掺杂材料。

25. 发明授权

US08488704B2 Method for selecting subchannel mode and MIMO communication system using the same 失效
标题翻译：用于选择子信道模式的方法和使用其的MIMO通信系统
公开(公告)号：US08488704B2
公开(公告)日：2013-07-16
申请号：US12370428
申请日：2009-02-12
申请人： Jie Zhang , Hua Zhou , Jinyin Xue
发明人： Jie Zhang , Hua Zhou , Jinyin Xue
IPC分类号： H04L1/02 , H04B7/02
CPC分类号： H04L1/0001
摘要： The invention relates to Method for Selecting Subchannel Mode and MIMO Communication System Using the Same. A method for self-adaptively selecting a code modulation sub-channel mode is suitably used in a MIMO communication system that comprises a base station and mobile terminals, wherein the method comprises the steps of: the mobile terminal estimating channel state information thereof, and determining a sub-channel structure most suitable for data transmission thereto, based on the channel state information; the mobile terminal feeding back information on the determined sub-channel structure most suitable for data transmission thereto to the base station; and the base station determining a sub-channel structure used for a down link, based on the information on the sub-channel structure fed back by the mobile terminal. According to the present invention, the subchannel structure in the communication system can be self-adaptively changed according to the actual communication environment, so as to improve the entire communication quality and efficiency.
摘要翻译：本发明涉及用于选择子信道模式的方法和使用该信道模式的MIMO通信系统。一种用于自适应地选择码调制子信道模式的方法适用于包括基站和移动终端的MIMO通信系统，其中该方法包括以下步骤：移动终端估计其信道状态信息，并确定基于信道状态信息最适合于数据传输的子信道结构; 所述移动终端将关于所述确定的最适合于向所述基站的数据传输的子信道结构的信息反馈给所述基站; 并且基于由移动终端反馈的子信道结构的信息，基站确定用于下行链路的子信道结构。根据本发明，通信系统中的子信道结构可以根据实际的通信环境自适应地改变，从而提高整个通信质量和效率。

26. 发明授权

US08470825B2 Diazabenzo[de] anthracen-3-one compounds and methods for inhibiting PARP 失效
标题翻译：二氮杂苯并[de]蒽-3-酮化合物和抑制PARP的方法
公开(公告)号：US08470825B2
公开(公告)日：2013-06-25
申请号：US13246169
申请日：2011-09-27
申请人： Weizheng Xu , Greg Delahanty , Jie Zhang
发明人： Weizheng Xu , Greg Delahanty , Jie Zhang
IPC分类号： A61K31/5025
CPC分类号： C07D491/06 , A61K31/495 , A61K31/5025
摘要： The present invention relates to diazabenzo[de]anthracen-3-one compounds which inhibit poly(ADP-ribose) polymerase (“PARP”), compositions containing these compounds and methods for using these PARP inhibitors to treat, prevent and/or ameliorate the effects of the conditions described herein.
摘要翻译：本发明涉及抑制聚（ADP-核糖）聚合酶（“PARP”）的二氮杂苯并[de]蒽-3-酮化合物，含有这些化合物的组合物和使用这些PARP抑制剂治疗，预防和/或改善本文所述条件的效果。

27. 发明授权

US08459343B2 Thermal module assembly and heat sink assembly having at least two engageable heat sinks 有权
标题翻译：热模块组件和散热器组件具有至少两个可接合的散热器
公开(公告)号：US08459343B2
公开(公告)日：2013-06-11
申请号：US12099171
申请日：2008-04-08
申请人： Jui-Wen Hung , Ching-Bai Hwang , Jie Zhang
发明人： Jui-Wen Hung , Ching-Bai Hwang , Jie Zhang
IPC分类号： F28F7/00
CPC分类号： H01L23/427 , F28D15/0233 , F28D15/0275 , F28F2275/14 , G06F1/20 , H01L23/3672 , H01L23/467 , H01L2924/0002 , Y10T29/4935 , H01L2924/00
摘要： A thermal module assembly includes a first thermal module (10) and a second thermal module (20). The first thermal module (10) has a fan (300) with an air outlet, a first heat sink (120) positioned at the air outlet and a first clamp portion (122) formed on the first heat sink (120). The second thermal module (20) has a second heat sink (220) and a second clamp portion (222) formed on the second heat sink (220). The second heat sink (220) is juxtaposed with the first heat sink (120). The first heat sink (120) and the second heat sink (220) are combined together via engagement of the first clamp portion (122) and the second clamp portion (222) so that airflow produced by the fan (300) flows past the first heat sink (120) and the second heat sink (220) in order.
摘要翻译：热模块组件包括第一热模块（10）和第二热模块（20）。第一热模块（10）具有带空气出口的风扇（300），位于空气出口处的第一散热器（120）和形成在第一散热器（120）上的第一夹紧部分（122）。第二热模块（20）具有形成在第二散热器（220）上的第二散热器（220）和第二夹紧部分（222）。第二散热器（220）与第一散热器（120）并置。第一散热器（120）和第二散热器（220）通过第一夹紧部分（122）和第二夹紧部分（222）的接合而组合在一起，使得由风扇（300）产生的气流经过第一散热器（120）和第二散热器（220）。

28. 发明申请

US20130140359A1 Method and System of Sending Information Based on a User Card 审中-公开
标题翻译：基于用户卡发送信息的方法和系统
公开(公告)号：US20130140359A1
公开(公告)日：2013-06-06
申请号：US13320720
申请日：2011-08-12
申请人： Rongsheng Xie , Jie Zhang , Zhenyu Qian , Chengxian Fan
发明人： Rongsheng Xie , Jie Zhang , Zhenyu Qian , Chengxian Fan
IPC分类号： G06F17/30
CPC分类号： G06F16/23 , G06Q20/4014 , G06Q20/405 , G06Q30/02 , G06Q30/0241
摘要： Sending information based on a user card includes obtaining, by a card terminal, identification information of the user card and sending identification information of the user card and identification information of the card terminal to a device, such as a data analysis and recommendation device. The data analysis and recommendation device determines whether recommendation information corresponding to the identification information of the user card and the identification information of the card terminal exists according to the identification information of the user card and the identification information of the card terminal, and if yes, sends the recommendation information to the card terminal. The data analysis and recommendation device can send the recommendation information to the card terminal and the card terminal can display the information to the user. As the recommendation information may be in different forms, personalized multimedia information can be provided to the user.
摘要翻译：基于用户卡的发送信息包括通过卡终端获取用户卡的识别信息，并将用户卡的识别信息和卡终端的识别信息发送到诸如数据分析和推荐设备的设备。数据分析和推荐装置根据用户卡的识别信息和卡终端的识别信息确定是否存在与用户卡的识别信息相对应的推荐信息和卡终端的识别信息，如果是，将推荐信息发送到卡终端。数据分析推荐装置可以向卡终端发送推荐信息，卡终端可以向用户显示信息。由于推荐信息可以是不同的形式，因此可以向用户提供个性化多媒体信息。

29. 发明申请

US20130022564A1 COMPOSITIONS AND METHODS FOR DERMALLY TREATING INFECTIONS 审中-公开
标题翻译：用于真皮治疗感染的组合物和方法
公开(公告)号：US20130022564A1
公开(公告)日：2013-01-24
申请号：US13556089
申请日：2012-07-23
申请人： Jie Zhang , Kevin S. Warner , Sanjay Sharma
发明人： Jie Zhang , Kevin S. Warner , Sanjay Sharma
IPC分类号： A61K31/522 , A61P31/12 , A61P31/10 , A61K31/4174
CPC分类号： A61K31/74 , A61K9/0014 , A61K9/7015 , A61K31/4174 , A61K31/522 , A61K47/12 , A61K47/18 , A61K47/32 , A61K47/38
摘要： The present invention is drawn to solidifying adhesive formulations, methods of drug delivery, and solidified layers for dermal delivery of a drug for treating various skin infections, such as fungal, bacterial, and/or viral skin infections. The formulation can include anti-infective drug, solvent vehicle, and solidifying agent. The solvent vehicle can include a volatile solvent system including at least one volatile solvent, and a non-volatile solvent system including at least one non-volatile solvent. The non-volatile solvent system can facilitate the delivery of the drug at therapeutically effective rates for sustained periods of time. The non-volatile solvent system can also act to plasticize the solidifying agent. The formulation can have a viscosity suitable for application to a skin surface prior to evaporation of the volatile solvents system. When applied to the skin, the formulation can form a solidified layer after at least a portion of the volatile solvent system is evaporated.
摘要翻译：本发明涉及固化粘合剂制剂，药物递送方法和用于皮肤递送用于治疗各种皮肤感染例如真菌，细菌和/或病毒性皮肤感染的药物的固化层。制剂可以包括抗感染药物，溶剂载体和固化剂。溶剂载体可以包括包含至少一种挥发性溶剂的挥发性溶剂体系和包含至少一种非挥发性溶剂的非挥发性溶剂体系。非挥发性溶剂体系可以有助于以治疗有效率持续持续时间的药物递送。非挥发性溶剂体系也可以起到塑化固化剂的作用。在挥发性溶剂体系蒸发之前，配方可以具有适用于皮肤表面的粘度。当施用于皮肤时，在挥发性溶剂体系的至少一部分蒸发后，制剂可以形成固化层。

30. 发明申请

US20130011365A1 PARP INHIBITOR COMPOUNDS, COMPOSITIONS AND METHODS OF USE 有权
标题翻译： PARP抑制剂化合物，组合物和使用方法
公开(公告)号：US20130011365A1
公开(公告)日：2013-01-10
申请号：US13527158
申请日：2012-06-19
申请人： Weizheng XU , Greg Delahanty , Ling Wei , Jie Zhang
发明人： Weizheng XU , Greg Delahanty , Ling Wei , Jie Zhang
IPC分类号： A61K31/519 , A61K33/24 , A61K31/7008 , A61K38/21 , A61K31/7036 , A61K31/7048 , A61K31/664 , A61P35/00 , A61P35/02 , A61K38/14 , A61K31/704 , A61K38/20
CPC分类号： A61K31/519 , A61K31/53 , C07D487/06 , C07D519/00
摘要： The present invention relates to tetraaza phenalen-3-one compounds which inhibit poly (ADP-ribose) polymerase (PARP) and are useful in the chemosensitization of cancer therapeutics. The induction of peripheral neuropathy is a common side-effect of many of the conventional and newer chemotherapies. The present invention further provides means to reliably prevent or cure chemotherapy-induced neuropathy. The invention also relates to the use of the disclosed PARP inhibitor compounds in enhancing the efficacy of chemotherapeutic agents such as temozolomide. The invention also relates to the use of the disclosed PARP inhibitor compounds to radio sensitize tumor cells to ionizing radiation. The invention also relates to the use of the disclosed PARP inhibitor compounds for treatment of cancers with DNA repair defects.
摘要翻译：本发明涉及抑制聚（ADP-核糖）聚合酶（PARP）并可用于癌症治疗剂的化学敏化的四氮芥苯并三氮唑-3-酮化合物。周围神经病变的诱导是许多常规和较新的化学疗法的常见副作用。本发明还提供了可靠地预防或治愈化疗诱发的神经病变的方法。本发明还涉及所公开的PARP抑制剂化合物在增强化疗剂如替莫唑胺的功效中的用途。本发明还涉及所公开的PARP抑制剂化合物对肿瘤细胞对电离辐射的敏感性的应用。本发明还涉及所公开的PARP抑制剂化合物用于治疗具有DNA修复缺陷的癌症的用途。

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