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    • 26. 发明授权
    • Process for manufacture of polytrimethylene ether glycol
    • 聚三亚甲基醚二醇的制备方法
    • US07161045B1
    • 2007-01-09
    • US11204731
    • 2005-08-16
    • Hari Babu SunkaraHoward C. NgWei Zheng
    • Hari Babu SunkaraHoward C. NgWei Zheng
    • C07C43/11C08J3/26
    • C08G65/48C08G65/34
    • A process of manufacture of polytrimethylene ether glycol comprising:(a) polycondensing reactant comprising diol selected from the group consisting of 1,3-propanediol, 1,3-propanediol dimer and 1,3-propanediol trimer or mixtures thereof in the presence of acid polycondensation catalyst to form polytrimethylene ether glycol;(b) adding water to the polytrimethylene ether glycol and hydrolyzing the acid esters formed during the polycondensation to form a hydrolyzed mixture containing the polytrimethylene ether glycol and the hydrolyzed acid esters;(c) adding organic solvent that is miscible with water to the hydrolyzed mixture to form an aqueous-organic mixture comprising (i) organic phase containing polytrimethylene ether glycol and residual acid polycondensation catalyst from the polycondensing and (ii) water phase;(d) separating the water phase and the organic phase;(e) adding base to the separated organic phase to neutralize the residual acid polycondensation catalyst by forming salts of the residual acid polycondensation catalyst;(f) separating the organic phase into (i) liquid phase comprising the polytrimethylene ether glycol, the organic solvent and any residual water, and (ii) solid phase comprising the salts of the residual acid polycondensation catalyst and the base which is unreacted; and(g) removing the organic solvent and the residual water from the organic phase to obtain polytrimethylene ether glycol.
    • 一种制备聚三亚甲基醚二醇的方法,包括:(a)在酸存在下,包含选自1,3-丙二醇,1,3-丙二醇二聚物和1,3-丙二醇三聚物或其混合物的二醇的缩聚反应物 缩聚催化剂形成聚三亚甲基醚二醇; (b)向聚三亚甲基醚二醇中加水并水解缩聚过程中形成的酸酯,形成含有聚三亚甲基醚二醇和水解酸酯的水解混合物; (c)将与水混溶的有机溶剂加入到水解混合物中以形成水 - 有机混合物,其包含(i)聚缩聚和(ii)水相中含有聚三亚甲基醚二醇和残余酸缩聚催化剂的有机相; (d)分离水相和有机相; (e)通过形成残余酸缩聚催化剂的盐,将分离的有机相加入碱中和残留的酸缩聚催化剂; (f)将有机相分离成(i)包含聚三亚甲基醚二醇,有机溶剂和任何残留水的液相,和(ii)包含残余酸缩聚催化剂的盐和未反应的碱的固相; 和(g)从有机相中除去有机溶剂和残余水,得到聚三亚甲基醚二醇。