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    • 22. 发明授权
    • Disazo photoreceptors for electrophotography
    • 用于电子照相术的二重唑光感受器
    • US4537847A
    • 1985-08-27
    • US640205
    • 1984-08-10
    • Jiro TakahashiKiyoshi SawadaAkira KinoshitaTawara KomamuraSatoshi GotoOsamu Sasaki
    • Jiro TakahashiKiyoshi SawadaAkira KinoshitaTawara KomamuraSatoshi GotoOsamu Sasaki
    • C09B35/02C09B56/04G03G5/06
    • C09B35/02C09B56/04G03G5/0677G03G5/0683G03G5/0685
    • Photoreceptor for electrophotography comprising a conductive support and an overlaying photosensitive layer thereon, said photosensitive layer containing at least one azo compound of Formula I or II ##STR1## wherein Ar.sub.1, Ar.sub.2, Ar.sub.3 and Ar.sub.4 each is an aromatic hydrocarbon ring radical or an aromatic heterocyclic ring radical; R.sub.1, R.sub.2, R.sub.3 and R.sub.4 each is an electron attractive group or hydrogen provided that at least one of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 is an electron attractive group; and A is ##STR2## wherein X is a hydroxy group or a group represented by the formula: ##STR3## wherein R.sub.6 and R.sub.7 each is hydrogen or an alkyl group, and R.sub.8 is an alkyl or aryl group; Y is halogen, an alkyl or alkoxy group, a carboxy group, a sulfo group, a carbamoyl or sulfamoyl group; Z is an atomic group necessary for making an aromatic hydrocarbon ring or an aromatic heterocyclic ring; R.sub.5 is hydrogen, an amino or carbamoyl group, a carboxy group or an ester group thereof; Ar.sub.5 is an aryl group; n is an integer of 1, 2 or 3; and m is an integer of 0, 1 or 2.
    • 用于电子照相的感光体包括导电支撑体和其上的覆盖感光层,所述感光层含有至少一种式I或II式II的偶氮化合物,其中Ar1,Ar2,Ar3和Ar4各自为芳族 烃环基或芳族杂环基; R 1,R 2,R 3和R 4各自是吸电子基团或氢,条件是R 1,R 2,R 3和R 4中的至少一个是吸电子基团; 其中X为羟基或由下式表示的基团:其中R 6和R 7各自为氢或烷基,R 8为烷基或芳基 组; Y是卤素,烷基或烷氧基,羧基,磺基,氨基甲酰基或氨磺酰基; Z是制备芳族烃环或芳族杂环所必需的原子团; R5是氢,氨基或氨基甲酰基,羧基或其酯基; Ar5是芳基; n为1,2或3的整数; m为0,1或2的整数。
    • 23. 发明授权
    • Electrophotographic substituted p,p'-bisazo diphenyl acrylonitrile
compounds for photoreceptors
    • 用于光感受器的电子照相取代的p,p'-双偶氮二苯基丙烯腈化合物
    • US4495261A
    • 1985-01-22
    • US453281
    • 1982-12-27
    • Jiro TakahashiTawara KomamuraKiyoshi SawadaSsamu SasakiSatoshi GotoAkira Kinoshita
    • Jiro TakahashiTawara KomamuraKiyoshi SawadaSsamu SasakiSatoshi GotoAkira Kinoshita
    • G03G5/06
    • G03G5/0683
    • An electrophotograhic photoreceptor that has great ability to generate carriers and which has high sensitivity but low residual potential is disclosed. This photoreceptor is characterized by having formed on an electrically conductive support a light-sensitive layer containing a bisazo compound of the following formula: ##STR1## (wherein R.sub.1 is a cyano group, a chlorine atom or a bromine atom; X.sub.1 is a halogen atom, an alkyl group, an alkoxy group or a cyano group; X.sub.2 is a hydrogen atom, a halogen atom, an alkyl atom or an alkoxy group; A is ##STR2## wherein Y is a substituted or unsubstituted carbamoyl group or a substituted or unsubstituted sulfamoyl group; Z is an atomic group necessary for forming a substituted or unsubstituted aromatic hydrocarbon ring or a substituted or unsubstituted heteroaromatic ring; R.sub.2 is a hydrogen atom, a substituted or unsubstituted amino group, a substituted or unsubstituted carbamoyl group, a carboxy group or an ester group thereof; and A' is a substituted or unsubstituted aryl group).
    • 公开了具有很高的灵敏度但低残留电位的产生载体的能力的电子照相感光体。 该感光体的特征在于在导电载体上形成含有下式的双偶氮化合物的光敏层:其中R1是氰基,氯原子或溴原子; X1是卤素原子 ,烷基,烷氧基或氰基; X 2为氢原子,卤素原子,烷基或烷氧基; A为取代或未取代的氨基甲酰基或取代或未取代的氨基甲酰基 氨磺酰基; Z是形成取代或未取代的芳族烃环或取代或未取代的杂芳环所需的原子团; R 2是氢原子,取代或未取代的氨基,取代或未取代的氨基甲酰基,羧基或 其酯基; A'为取代或未取代的芳基)。
    • 24. 发明授权
    • Light-sensitive photographic element comprising a magenta image
dye-providing compound
    • US4256831A
    • 1981-03-17
    • US68508
    • 1979-08-22
    • Masaru KanbeKazumasa WatanabeMorito UemuraJiro TakahashiRyuichiro KobayashiTatsuhiko Kobayashi
    • Masaru KanbeKazumasa WatanabeMorito UemuraJiro TakahashiRyuichiro KobayashiTatsuhiko Kobayashi
    • G03C7/00C09B29/01C09B29/28G03C8/10G03C1/10G03C1/40G03C5/54
    • G03C8/10C09B29/0003C09B29/28
    • A light-sensitive photographic element comprising a support and at least one light-sensitive silver halide emulsion layer coated thereon having associated therewith a magenta image dye-providing compound which releases a magenta dye or a precursor thereof corresponding to the imagewise exposure of said emulsion layer, said magenta dye-providing compound being a compound represented by formula [I]: ##STR1## wherein Car represents a carrier moiety which can be oxidized under alkaline conditions to release a diffusible dye or a precursor thereof from said compound;R.sup.1 and R.sup.2, which may be the same or different, independently represent a hydrogen atom or an alkyl group having 1 to 3 carbon atoms (provided that the total sum of carbon atoms in R.sup.1 and R.sup.2 does not exceed 5), or R.sup.1 and R.sup.2 may form, together with the nitrogen atom, ##STR2## X represents a hydroxyl group, a salt thereof or a group, which can be converted into a hydroxyl group by hydrolysis, having the following formula: ##STR3## in which R.sup.3 represents an alkyl or haloalkyl group having 1 to 18 carbon atoms or a phenyl group which may be substituted; Y represents a ##STR4## group in which R.sup.4 and R.sup.5, which may be the same or different, independently represent a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or a cycloalkyl group (provided that the total sum of carbon atoms in R.sup.4 and R.sup.5 does not exceed 6);Z represents a hydrogen atom, a chlorine atom, a methyl group or a methoxy group;l is 1 or 2 provided that when l is 2 each Z may be the same or different;m is 0 or 1;andJ represents a bivalent linking group having the formula --R.sup.6 --(O).sub.n --R.sub.p.sup.7 -- in which R.sup.6 and R.sup.7, which may be the same or different, independently represent an alkylene group having 1 to 8 carbon atoms, a phenylene group which may be substituted; n represents 0 or 1; p represents 0 or 1 provided that p is 1 when n is 1 and 1 or 0 when n is 0 (provided that, when p is 1, the total sum of carbon atoms in R.sup.6 and R.sup.7 does not exceed 13).
    • 28. 发明申请
    • Agent for Alleviating Vascular Failure
    • 缓解血管功能衰竭的药物
    • US20090099255A1
    • 2009-04-16
    • US11887329
    • 2006-03-31
    • Naoki HigashiJiro Takahashi
    • Naoki HigashiJiro Takahashi
    • A61K31/352A61K31/122A61P9/00
    • A61K31/355A23G1/32A23G3/36A23G4/06A23K20/174A23K20/179A23L2/52A23L13/40A23L17/00A23L33/105A23L33/15A23V2002/00A61K31/122A61K2300/00A23V2250/032A23V2250/708A23V2250/712A23V2200/326A23V2250/202
    • [Object] In recent years, life style-related diseases, particularly circulatory system diseases caused by the tendency toward high caloric diet, the change in life style, lack of exercise, stress and so on increased and have became a serious social problem. These diseases are caused mainly by injures in blood vessels. To prevent injures in blood vessels, there has been required a vascular endothelial cell-protecting agent and a food having an effect of protecting vascular endothelial cells.[Means to solve] It is possible to provide an agent for alleviating, treating and preventing vascular failure and a vascular endothelial cell-protecting agent characterized by containing, as an effective ingredient, at least one active oxygen scavenger such as astaxanthin and tocotrienols; and a food, a drink and an animal feed each having an effect of alleviating, treating and preventing vascular failure and an effect of protecting vascular endothelial cells characterized by containing, as the effective ingredient, at least one active oxygen scavenger such as astaxanthin and tocotrienols.
    • 近年来,生活方式相关疾病,特别是高热量饮食倾向引起的循环系统疾病,生活方式的变化,运动缺乏,压力等增加,已成为严重的社会问题。 这些疾病主要是由血管损伤引起的。 为了防止血管受伤,需要血管内皮细胞保护剂和具有保护血管内皮细胞作用的食物。 [解决方案]可以提供减轻,治疗和预防血管破坏的药剂和特征在于含有至少一种活性氧清除剂如虾青素和生育三烯酚作为有效成分的血管内皮细胞保护剂; 以及各自具有减轻,治疗和预防血管破坏的作用的食物,饮料和动物饲料以及保护血管内皮细胞的作用,其特征在于含有至少一种活性氧清除剂,例如虾青素和生育三烯酚 。
    • 30. 发明申请
    • Gene expression regulating agent
    • 基因表达调控剂
    • US20080269349A1
    • 2008-10-30
    • US12155914
    • 2008-06-11
    • Yuji NaitoJiro TakahashiWataru Aoi
    • Yuji NaitoJiro TakahashiWataru Aoi
    • A61K31/122A61P3/10
    • A61K31/122A23L2/52A23L33/10A23L33/105A23V2002/00A61K31/21
    • An object of the invention is to provide a gene expression regulating agent which includes astaxanthin and/or its ester as an effective ingredient; and a food and drink having an effect of regulating gene expression which includes astaxanthin and/or its ester. Abnormal gene expression due to, for example, oxidative stress can be treated, improved, and/or prevented, and diseases caused by the abnormal gene expression can be treated, improved, and/or prevented. A gene expression regulating agent which includes astaxanthin and/or its ester as an effective ingredient; and a food and drink having an effect of regulating gene expression which includes astaxanthin and/or its ester are provided and are useful for treating, improving, and/or preventing the symptom caused by the abnormal gene expression, that is, excessive expression or suppression of expression.
    • 本发明的目的是提供一种包含虾青素和/或其酯作为有效成分的基因表达调节剂; 以及具有调节基因表达的作用的食品和饮料,其包括虾青素和/或其酯。 可以治疗,改善和/或预防由于例如氧化应激引起的异常基因表达,并且可以治疗,改善和/或预防由异常基因表达引起的疾病。 包含虾青素和/或其酯作为有效成分的基因表达调节剂; 并且提供具有调节基因表达的作用的食物和饮料,其包括虾青素和/或其酯,并且可用于治疗,改善和/或预防由异常基因表达引起的症状,即过度表达或抑制 的表达。