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21. 发明授权

US5769796A Super-elastic composite guidewire 失效
标题翻译：超弹性复合导丝
公开(公告)号：US5769796A
公开(公告)日：1998-06-23
申请号：US789607
申请日：1997-01-22
申请人： Thomas J. Palermo , Gene Samson , Gregory E. Mirigian , U. Hiram Chee , Erik T. Engelson , Edward Snyder
发明人： Thomas J. Palermo , Gene Samson , Gregory E. Mirigian , U. Hiram Chee , Erik T. Engelson , Edward Snyder
IPC分类号： A61B5/00
CPC分类号： A61M25/09 , A61M2025/09091 , A61M2025/09175
摘要： This is a composite guidewire for use in a catheter and is used for accessing a targeted site in a lumen system of a patient's body. The guidewire core or guidewire section may be of a stainless steel or a high elasticity metal alloy, preferably a Ni--Ti alloy, also preferably having specified physical parameters. The composite guidewire assembly is especially useful for accessing peripheral or soft tissue targets. Variations include multi-section guidewire assemblies having (at least) super-elastic distal portions and super-elastic braided reinforcements along the mid or distal sections. A variation of the inventive guidewire includes the coating of the wire with a tie layer and then with a one or more lubricious polymers to enhance its suitability for use within catheters and with the interior of vascular lumen.
摘要翻译：这是用于导管的复合导丝，并用于进入患者体内的管腔系统中的目标部位。导丝芯或导丝部分可以是不锈钢或高弹性金属合金，优选Ni-Ti合金，也优选具有特定的物理参数。复合导丝组件对于接近外周或软组织靶是特别有用的。变型包括具有（至少）超弹性远端部分的多段导丝组件和沿着中部或远端部分的超弹性编织加强件。本发明的导丝的变体包括用连接层涂覆线材，然后使用一种或多种润滑聚合物来增强其在导管内和血管腔内部使用的适用性。

22. 发明授权

US5749837A Enhanced lubricity guidewire 失效
标题翻译：增强润滑性导丝
公开(公告)号：US5749837A
公开(公告)日：1998-05-12
申请号：US695185
申请日：1996-08-01
申请人： Thomas J. Palermo , Gene Samson , Gregory E. Mirigian , U. Hiram Chee
发明人： Thomas J. Palermo , Gene Samson , Gregory E. Mirigian , U. Hiram Chee
IPC分类号： A61M25/00 , A61B5/00
CPC分类号： A61M25/09 , A61M2025/0046 , A61M2025/09091 , A61M2025/09133 , A61M2025/09175
摘要： This invention is a surgical device. It is a guidewire for use in a catheter and is used for accessing a targeted site in a lumen system of a patient's body. The guidewire or guidewire section may be of a stainless steel or a high elasticity metal alloy, preferably a Ni--Ti alloy, having specified physical parameters. The guidewire is especially useful for accessing peripheral or soft tissue targets. A special variation of the inventive guidewire includes the coating of the wire with a tie layer and then with a one or more lubricious polymers to enhance its suitability for use within catheters and with the interior of vascular lumen.
摘要翻译：本发明是一种手术装置。它是用于导管的导丝，用于进入患者身体的管腔系统中的目标部位。导线或导丝部分可以是具有特定物理参数的不锈钢或高弹性金属合金，优选Ni-Ti合金。导丝对于访问外周或软组织靶是特别有用的。本发明的导丝的特殊变型包括用连接层涂覆线材，然后用一种或多种润滑聚合物涂覆，以增强其在导管内和血管腔内部使用的适用性。

23. 发明授权

US5578074A Implant delivery method and assembly 失效
标题翻译：植入物交付方式和装配
公开(公告)号：US5578074A
公开(公告)日：1996-11-26
申请号：US363232
申请日：1994-12-22
申请人： Gregory E. Mirigian
发明人： Gregory E. Mirigian
IPC分类号： A61F2/82 , A61B17/00 , A61B17/12 , A61F2/00 , A61F2/06
CPC分类号： A61B17/1214 , A61B17/12022 , A61B2017/12063 , A61B2017/12068 , A61B2017/12077 , A61F2002/30095 , A61F2210/0023
摘要： A thermally activated occlusive implant delivery assembly is provided. The assembly includes an occlusive implant device and a pusher. The pusher has a distal section and a proximal section. The distal section includes a coupling portion which is shape memory material and exhibits different configurations depending on the coupling portion's temperature. The coupling portion interlockingly engages the implant when it is in one of the configurations and releases the implant from interlocking engagement therewith when in another one of the configurations. In operation, the assembly is introduced into the body of a mammal via a guide catheter suited for the particular lumen being navigated. When the implant is positioned at the desired site, the coupling portion of the pusher is thermally activated to effect the return of its original, pre-set configuration, which is originally formed to release the implant from interlocking engagement therewith. The pusher can then be readily removed from the mammal without imparting any significant force on the implant during retraction.
摘要翻译：提供热活化闭塞植入物递送组件。组件包括闭塞植入装置和推动器。推动器具有远端部分和近端部分。远侧部分包括耦合部分，其是形状记忆材料，并且根据耦合部分的温度呈现不同的构型。当处于其中一个构造时，联接部分与植入物互锁地接合，并且当处于另一种构造时，将植入物与其互锁接合释放。在操作中，组件通过适合于正在导航的特定管腔的导管引入哺乳动物体内。当植入物定位在期望的位置时，推动器的联接部分被热活化，以实现其原始形成的初始构造的返回，其原始形成为将植入物与其互锁接合释放。然后可以从哺乳动物容易地移除推动器，而不会在收缩期间对植入物施加任何显着的力。

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